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759 results

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Page 1
Summary of Research: Aflibercept 8 mg versus Faricimab Treat‑and‑Extend for Diabetic Macular Edema or Neovascular Age‑Related Macular Degeneration: A Bayesian Fixed‑Effect Network Meta‑analysis of Clinical Trials.
Friedman SM, Xu Y, Sherman S, Kuznik A, Mojebi A, Keeping S, Chan K, Leng T, Patel NA. Friedman SM, et al. Ophthalmol Ther. 2026 Aug;15(8):2515-2518. doi: 10.1007/s40123-026-01434-w. Epub 2026 Jun 23. Ophthalmol Ther. 2026. PMID: 42332210 Free PMC article.
A Response to: Letter to the Editor Regarding "Aflibercept 8 mg Versus Faricimab Treat-and-Extend for Diabetic Macular Edema or Neovascular Age-Related Macular Degeneration: A Bayesian Fixed-Effect Network Meta-analysis of Clinical Trials".
Friedman SM, Xu Y, Sherman S, Kuznik A, Mojebi A, Keeping S, Chan K, Leng T, Patel N. Friedman SM, et al. Ophthalmol Ther. 2026 Jul 11. doi: 10.1007/s40123-026-01439-5. Online ahead of print. Ophthalmol Ther. 2026. PMID: 42435129 No abstract available.
Tremelimumab with or without durvalumab in combination with paclitaxel in metastatic urothelial cancer: phase I/II ICRA trial.
Einerhand SMH, Ali H, Wong SQ, van Dorp J, van Maanen T, de Feijter JM, Montfoort MLV, Boellaard TN, Braaf LM, Brugman W, Vis DJ, Hollander CMJ, Daletzakis A, Schrijver HA, Snapper K, Oosting SF, Bruijnen CP, Wessels LFA, Chan KS, Suelmann BBM, van der Heijden MS. Einerhand SMH, et al. Among authors: chan ks. Nat Commun. 2026 Jun 17;17(1):7679. doi: 10.1038/s41467-026-74570-3. Nat Commun. 2026. PMID: 42310313 Free PMC article. Clinical Trial.
Early life stress induces brain-wide electrical network predisposition to migraine.
Johnson M, Eberle M, Hultman I, Zhang X, Filali Y, Hing B, Matkovich M, Jimenez A, Mitchell S, Adegboyo A, Velamuri R, Miller J, Chan KS, Srivastava S, Hultman R. Johnson M, et al. J Headache Pain. 2026 Jun 13;27(1):177. doi: 10.1186/s10194-026-02399-8. J Headache Pain. 2026. PMID: 42288719 Free PMC article.
In Reply to Cao and Wang.
Chiang CL, Chan KSK, Yeung RWL, Chiu KWH. Chiang CL, et al. Int J Radiat Oncol Biol Phys. 2026 Jul 1;125(3):982-983. doi: 10.1016/j.ijrobp.2026.02.246. Int J Radiat Oncol Biol Phys. 2026. PMID: 42259323 No abstract available.
Global genetic interaction network of a human cell maps conserved principles and informs functional interpretation of gene co-essentiality profiles.
Billmann M, Costanzo M, Zhang X, Hassan AZ, Rahman M, Brown KR, Chan KS, Tong AHY, Pons C, Ward HN, Ross C, van Leeuwen J, Aregger M, Lawson KA, Mair B, Roth AF, Sen NE, Forster DT, Tan G, Mero P, Masud SN, Lee Y, Aguilera-Uribe M, Ušaj M, Almeida SMT, Aulakh K, Bhojoo U, Birkadze S, Budijono N, Cai X, Caumanns JJ, Chalmers JJ, Chandrashekhar M, Chang D, Climie R, Dasgupta K, Drazic A, Echenique JIR, Gacesa R, Farias AG, Habsid A, Horecka I, Kantautas K, Ji F, Kim DK, Lee SY, Liang W, Lim HJ, Lin K, Lu X, Maier M, Nami B, Nixon A, Mikolajewicz N, Mokhtaridoost M, Nedyalkova L, Rohde T, Rodrigues MS, Soste M, Schultz E, Wang W, Seetharaman A, Shuteriqi E, Sizova O, Taylor DT, Tereshchenko M, Tieu D, Turowec J, Ubhi T, Varland S, Wang KE, Wang ZY, Wei J, Xiao YX, Maass PG, Reversade B, Brown GW, Cravatt BF, Dixon SJ, Wyatt HDM, Röst HL, Roth FP, Xia T, Bader GD, Loewith R, Davis NG, Andrews B, Myers CL, Moffat J, Boone C. Billmann M, et al. Cell. 2026 Jun 11;189(12):3736-3759.e58. doi: 10.1016/j.cell.2026.03.044. Epub 2026 Apr 27. Cell. 2026. PMID: 42049019 Free PMC article.
Nitric oxide-dependent stabilization of vimentin confers chemoresistance in ovarian cancer.
Melone G, Bayraktar R, Zhao H, Hynes SO, Kaar F, Freegrove A, Deng J, Baseviciene A, Uzair I, Martinez KO, Guzman-Rojas L, Chervo MF, Li M, Qian W, Zhou J, Phillips A, Zambo KDA, Nikolos F, Chan KS, Thomas C, Francis L, Chang JC. Melone G, et al. Mol Ther Nucleic Acids. 2026 Apr 4;37(2):102924. doi: 10.1016/j.omtn.2026.102924. eCollection 2026 Jun 16. Mol Ther Nucleic Acids. 2026. PMID: 42023030 Free PMC article.
Chemotherapy-induced activation of caspase-1 and IL-1α release by cancer cells remotely skews myelopoiesis to drive pro tumorigenic systemic neutrophil-dominant inflammation.
Wong SQ, Hayashi K, Subel EJ, Huang YH, Gao H, Garcia HE, Porter SJ, Karabicici M, Hoi XP, Alonzo MD, Kasabyan A, Tsouko E, Shin CS, Bouchier-Hayes L, Korentzelos D, Chen C, Brooks M, Yin Z, Titus RS, Zhou L, Gong Y, Li Y, Wong ST, El-Zaatari Z, Kaushik D, Satkunasivam R, Nikolos F, Chan KS. Wong SQ, et al. Nat Commun. 2026 Apr 20;17(1):4724. doi: 10.1038/s41467-026-71471-3. Nat Commun. 2026. PMID: 42009646 Free PMC article.
UniST: A Unified Computational Framework for 3D Spatial Transcriptomics Reconstruction.
Shui L, Liu Y, Lubo Julio IC, Clemenceau JR, Hoi XP, Dai Y, Lu W, Min J, Khan K, Roemer B, Jiang M, Waters RE, Colbert K, Maitra A, Wintermark M, Yuan Y, Chan KS, Hwang TH, Mansfield PF, Davis J, Solis Soto LM, Wang L, Li L, Li Z. Shui L, et al. bioRxiv [Preprint]. 2026 Mar 16:2026.03.12.711362. doi: 10.64898/2026.03.12.711362. bioRxiv. 2026. PMID: 41889901 Free PMC article. Preprint.
Cross-site quantitative MRI harmonization: The impact on age modeling in health and disease.
Chen X, Ocampo-Pineda M, Lu PJ, Ekerdt C, Weigel M, Jansen MG, Cagol A, Chan KS, Schädelin S, Zwiers M, Oosterman JM, Norris DG, Bayer JMM, Marquand AF, Menks WM, Kuhle J, Kappos L, Melie-Garcia L, Granziera C, Marques JP. Chen X, et al. Imaging Neurosci (Camb). 2026 Feb 24;4:IMAG.a.1140. doi: 10.1162/IMAG.a.1140. eCollection 2026. Imaging Neurosci (Camb). 2026. PMID: 41756306 Free PMC article.
Axon Diameter Mapping From Myelin Water Diffusion MRI.
Lee HH, Chan KS, Novikov DS, Fieremans E, Huang SY. Lee HH, et al. IEEE Trans Med Imaging. 2026 Jun;45(6):2883-2896. doi: 10.1109/TMI.2026.3664328. IEEE Trans Med Imaging. 2026. PMID: 41686667 Free PMC article.
Compensatory Hypertrophy and Changes of Liver Function After Sequential Transarterial Chemoembolization, Stereotactic Body Radiation Therapy, and Immunotherapy (START-FIT) in Unresectable Hepatocellular Carcinoma.
Yeung RWL, Chiu KWH, Chan KSK, Wong NSM, Chen W, Lee VWY, Lee FAS, Chan ACY, Chiang CL. Yeung RWL, et al. Int J Radiat Oncol Biol Phys. 2026 Jul 1;125(3):852-862. doi: 10.1016/j.ijrobp.2025.12.019. Epub 2025 Dec 23. Int J Radiat Oncol Biol Phys. 2026. PMID: 41448501
Cellular senescence in precancer lesions and early-stage cancers.
Hoi XP, Stangis MM, Glass SE, Kim JH, Kang SW, Brennen WN, Li Z, Grady WM, Yegnasubramanian S, Kuhn P, Lyssiotis CA, Sagara A, Shrubsole MJ, Kadara H, Yuan Y, Coffey RJ, Lau KS, De Marzo AM, Maitra A, Min J, Yu M, Chan KS; TBEL Consortium. Hoi XP, et al. Cancer Cell. 2026 Jan 12;44(1):6-11. doi: 10.1016/j.ccell.2025.10.006. Epub 2025 Nov 6. Cancer Cell. 2026. PMID: 41202812 Free PMC article. Review.
Unraveling Microstructural and Macrostructural Brain Age Dynamics in Multiple Sclerosis.
Chen X, Lu PJ, Ocampo-Pineda M, Cagol A, Schaedelin SA, Ruberte E, Weigel M, Spagnolo F, Benkert P, Lieb JM, Leppert D, Yaldizli Ö, Oechtering J, D'Souza M, Fischer-Barnicol B, Derfuss TJ, Ekerdt C, Menks WM, Chan KS, Zwiers M, Chan A, Hoepner R, Wagner F, Pot C, Du Pasquier RA, Finkener S, Diepers M, Bridel C, Lalive PH, Uginet M, Gobbi C, Zecca C, Pravatà E, Disanto G, Roth P, Vehoff J, Mueller S, Chan-Hi Kim O, Kappos L, Kuhle J, Melie-Garcia L, Marques JP, Granziera C. Chen X, et al. Neurol Neuroimmunol Neuroinflamm. 2025 Sep;12(5):e200459. doi: 10.1212/NXI.0000000000200459. Epub 2025 Aug 19. Neurol Neuroimmunol Neuroinflamm. 2025. PMID: 40829091 Free PMC article.
A global genetic interaction map of a human cell reveals conserved principles of genetic networks.
Billmann M, Costanzo M, Zhang X, Hassan AZ, Rahman M, Brown KR, Chan KS, Tong AHY, Pons C, Ward HN, Ross C, van Leeuwen J, Aregger M, Lawson KA, Mair B, Roth AF, Sen NE, Forster D, Tan G, Mero P, Masud SN, Lee Y, Aguilera-Uribe M, Usaj M, Almeida SMT, Aulakh K, Bhojoo U, Birkadze S, Budijono N, Cai X, Caumanns JJ, Chandrashekhar M, Chang D, Climie R, Dasgupta K, Drazic A, Rojas Echenique JI, Gacesa R, Granda Farias A, Habsid A, Horecka I, Kantautas K, Ji F, Kim DK, Lee SY, Liang W, Lim J, Lin K, Lu X, Nami B, Nixon A, Mikolajewicz N, Nedyalkova L, Rohde T, Sartori Rodrigues M, Soste M, Schultz E, Wang W, Seetharaman A, Shuteriqi E, Sizova O, Thomson Taylor D, Tereshchenko M, Tieu D, Turowec J, Ubhi T, Varland S, Wang KE, Wang ZY, Wei J, Xiao YX, Brown GW, Cravatt BF, Dixon SJ, Wyatt HDM, Röst HL, Roth FP, Xia T, Bader GD, Loewith R, Davis NG, Andrews B, Myers CL, Moffat J, Boone C. Billmann M, et al. bioRxiv [Preprint]. 2025 Jul 2:2025.06.30.662193. doi: 10.1101/2025.06.30.662193. bioRxiv. 2025. PMID: 40631273 Free PMC article. Preprint.
Visualizing cortical laminar architecture in the living human brain using next-generation ultra-high-gradient diffusion MRI.
Huang S, Lee H, Ma Y, Chan KS, Krijnen E, Eskandarian L, Bhatt A, Gerold J, Mahmutovic M, Puonti O, Zeng X, Binder LJD, Fischl B, Keil B, Ramos-Llordén G, Klawiter E, Lee HH. Huang S, et al. Res Sq [Preprint]. 2025 Jun 10:rs.3.rs-6724971. doi: 10.21203/rs.3.rs-6724971/v1. Res Sq. 2025. Update in: Commun Biol. 2026 Mar 23;9(1):651. doi: 10.1038/s42003-026-09887-2. PMID: 40585214 Free PMC article. Updated. Preprint.
Early Life Stress induces brain-wide electrical network predisposition to migraine.
Johnson M, Eberle M, Hultman I, Zhang X, Filali Y, Hing B, Matkovich M, Jimenez A, Mitchell S, Adegboyo A, Velamuri R, Miller J, Chan KS, Srivastava S, Hultman R. Johnson M, et al. bioRxiv [Preprint]. 2025 Sep 2:2024.11.14.622885. doi: 10.1101/2024.11.14.622885. bioRxiv. 2025. Update in: J Headache Pain. 2026 Jun 13;27(1):177. doi: 10.1186/s10194-026-02399-8. PMID: 40462923 Free PMC article. Updated. Preprint.
Acquired resistance in cancer: towards targeted therapeutic strategies.
Soragni A, Knudsen ES, O'Connor TN, Tognon CE, Tyner JW, Gini B, Kim D, Bivona TG, Zang X, Witkiewicz AK, Goodrich DW, Jiang D, Gammon ST, Willey CD, Boutros PC, Sandulache VC, Osman AA, Myers JN, Mehla K, Singh PK, Chan KS, Gao H, Marathe H; National Cancer Institute (NCI) Acquired Resistance to Therapy Network (ARTNet). Soragni A, et al. Nat Rev Cancer. 2025 Aug;25(8):613-633. doi: 10.1038/s41568-025-00824-9. Epub 2025 Jun 3. Nat Rev Cancer. 2025. PMID: 40461793 Free PMC article. Review.
Using surveillance data to evaluate the effectiveness of inactivated/mRNA COVID-19 vaccine boosters in preventing fatal outcomes among severe COVID-19 cases during the current ambit of SARS-CoV-2 XBB and JN.1 variant circulation.
Lo ESK, Wong LT, So SCY, Mohammad KN, Law KY, Chan KS, Chan CL, Lo D, Kung KH, Chuang SK. Lo ESK, et al. Front Public Health. 2025 May 14;13:1497399. doi: 10.3389/fpubh.2025.1497399. eCollection 2025. Front Public Health. 2025. PMID: 40438067 Free PMC article.
Heart rate variability in acute pancreatitis: a narrative review.
Liau MYQ, Liau JYJ, Selvakumar SV, Chan KS, Shelat VG. Liau MYQ, et al. Transl Gastroenterol Hepatol. 2024 Aug 21;9:68. doi: 10.21037/tgh-24-22. eCollection 2024. Transl Gastroenterol Hepatol. 2024. PMID: 39503030 Free PMC article. Review.
759 results