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Page 1
Idarubicin Dose Escalation During Consolidation Therapy for Adult Acute Myeloid Leukemia.
Bradstock KF, Link E, Di Iulio J, Szer J, Marlton P, Wei AH, Enno A, Schwarer A, Lewis ID, D'Rozario J, Coyle L, Cull G, Campbell P, Leahy MF, Hahn U, Cannell P, Tiley C, Lowenthal RM, Moore J, Cartwright K, Cunningham I, Taper J, Grigg A, Roberts AW, Benson W, Hertzberg M, Deveridge S, Rowlings P, Mills AK, Gill D, Bardy P, Campbell L, Seymour JF; Australasian Leukaemia & Lymphoma Group. Bradstock KF, et al. Among authors: coyle l. J Clin Oncol. 2017 May 20;35(15):1678-1685. doi: 10.1200/JCO.2016.70.6374. Epub 2017 Apr 3. J Clin Oncol. 2017. PMID: 28368672 Clinical Trial.
Consolidation therapy with low-dose thalidomide and prednisolone prolongs the survival of multiple myeloma patients undergoing a single autologous stem-cell transplantation procedure.
Spencer A, Prince HM, Roberts AW, Prosser IW, Bradstock KF, Coyle L, Gill DS, Horvath N, Reynolds J, Kennedy N. Spencer A, et al. Among authors: coyle l. J Clin Oncol. 2009 Apr 10;27(11):1788-93. doi: 10.1200/JCO.2008.18.8573. Epub 2009 Mar 9. J Clin Oncol. 2009. PMID: 19273705 Clinical Trial.
All-trans-retinoic acid, idarubicin, and IV arsenic trioxide as initial therapy in acute promyelocytic leukemia (APML4).
Iland HJ, Bradstock K, Supple SG, Catalano A, Collins M, Hertzberg M, Browett P, Grigg A, Firkin F, Hugman A, Reynolds J, Di Iulio J, Tiley C, Taylor K, Filshie R, Seldon M, Taper J, Szer J, Moore J, Bashford J, Seymour JF; Australasian Leukaemia and Lymphoma Group. Iland HJ, et al. Blood. 2012 Aug 23;120(8):1570-80; quiz 1752. doi: 10.1182/blood-2012-02-410746. Epub 2012 Jun 19. Blood. 2012. PMID: 22715121 Free article. Clinical Trial.
Prolonged administration of low-dose cytarabine and thioguanine in elderly patients with acute myeloid leukaemia (AML) achieves high complete remission rates and prolonged survival.
Arthur C, Jeffrey A, Yip E, Katsioulas V, Nalpantidis A, Kerridge I, Greenwood M, Coyle L, Mackinlay N, Fay K, Enjeti A, Shortt J, Stevenson W. Arthur C, et al. Among authors: coyle l. Leuk Lymphoma. 2020 Apr;61(4):831-839. doi: 10.1080/10428194.2019.1697876. Epub 2019 Dec 6. Leuk Lymphoma. 2020. PMID: 31809629
An MRD-stratified pediatric protocol is as deliverable in adolescents and young adults as in children with ALL.
Greenwood M, Trahair T, Sutton R, Osborn M, Kwan J, Mapp S, Howman R, Anazodo A, Wylie B, D'Rozario J, Hertzberg M, Irving I, Yeung D, Coyle L, Jager A, Engeler D, Venn N, Frampton C, Wei AH, Bradstock K, Dalla-Pozza L. Greenwood M, et al. Among authors: coyle l. Blood Adv. 2021 Dec 28;5(24):5574-5583. doi: 10.1182/bloodadvances.2021005576. Blood Adv. 2021. PMID: 34662896 Free PMC article.
Recombinant activated factor VII for the treatment of life-threatening haemorrhage.
Eikelboom JW, Bird R, Blythe D, Coyle L, Gan E, Harvey M, Isbister J, Leahy M, McIlroy D, Rahimpanah F, Ramanthan S, Strasser S, Ward C, Watts A, Towler S, Yi Q. Eikelboom JW, et al. Among authors: coyle l. Blood Coagul Fibrinolysis. 2003 Dec;14(8):713-7. doi: 10.1097/00001721-200312000-00004. Blood Coagul Fibrinolysis. 2003. PMID: 14614349
Intensive chemotherapy and up-front stem cell transplant for double hit lymphoma.
Othman J, Armytage T, Wong K, Arthur C, Fay K, Stevenson W, MacKinlay N, Ward C, Pechey V, Coyle L, Kerridge I, Greenwood M. Othman J, et al. Among authors: coyle l. Bone Marrow Transplant. 2020 Jul;55(7):1460-1463. doi: 10.1038/s41409-020-0789-5. Epub 2020 Jan 20. Bone Marrow Transplant. 2020. PMID: 31959892 No abstract available.
Unusual presentations of central nervous system myeloid sarcoma.
Chatterton S, Helou J, Drummond J, Gill AJ, Ward C, Coyle L, Kerridge I, Ng K. Chatterton S, et al. Among authors: coyle l. Intern Med J. 2022 Jun;52(6):1083-1088. doi: 10.1111/imj.15813. Intern Med J. 2022. PMID: 35718731
Pralatrexate in relapsed/refractory T-cell lymphoma: a retrospective multicenter study.
Bhurani M, Admojo L, Van Der Weyden C, Twigger R, Bazargan A, Quach H, Zimet A, Coyle L, Lindsay J, Radeski D, Hawkes E, Kennedy G, Irving I, Gutta N, Trotman J, Yeung J, Dunlop L, Hua M, Giri P, Yuen S, Panicker S, Moreton S, Khoo L, Scott A, Kipp D, McQuillan A, McCormack C, Dickinson M, Prince HM. Bhurani M, et al. Among authors: coyle l. Leuk Lymphoma. 2021 Feb;62(2):330-336. doi: 10.1080/10428194.2020.1827241. Epub 2020 Oct 7. Leuk Lymphoma. 2021. PMID: 33026266
Elevated serum FGF23 concentrations in plasma cell dyscrasias.
Stewart I, Roddie C, Gill A, Clarkson A, Mirams M, Coyle L, Ward C, Clifton-Bligh P, Robinson BG, Mason RS, Clifton-Bligh RJ. Stewart I, et al. Among authors: coyle l. Bone. 2006 Aug;39(2):369-76. doi: 10.1016/j.bone.2006.01.163. Epub 2006 Apr 27. Bone. 2006. PMID: 16644301
Axonal excitability in primary amyloidotic neuropathy.
Hafner J, Ghaoui R, Coyle L, Burke D, Ng K. Hafner J, et al. Among authors: coyle l. Muscle Nerve. 2015 Mar;51(3):443-5. doi: 10.1002/mus.24508. Epub 2015 Jan 16. Muscle Nerve. 2015. PMID: 25381694
Multicenter phase 3 study of the complement inhibitor eculizumab for the treatment of patients with paroxysmal nocturnal hemoglobinuria.
Brodsky RA, Young NS, Antonioli E, Risitano AM, Schrezenmeier H, Schubert J, Gaya A, Coyle L, de Castro C, Fu CL, Maciejewski JP, Bessler M, Kroon HA, Rother RP, Hillmen P. Brodsky RA, et al. Among authors: coyle l. Blood. 2008 Feb 15;111(4):1840-7. doi: 10.1182/blood-2007-06-094136. Epub 2007 Nov 30. Blood. 2008. PMID: 18055865 Free article. Clinical Trial.
Diuretics use in the management of bronchopulmonary dysplasia in preterm infants: A systematic review.
Ó Briain E, Byrne AO, Dowling J, Kiernan J, Lynch JCR, Alomairi L, Coyle L, Mulkerrin L, Mockler D, Fitzgerald G, Rehman LU, Semova G, Isweisi E, O'Sullivan A, O'Connor P, Mulligan K, Branagan A, Roche E, Meehan J, Molloy E. Ó Briain E, et al. Among authors: coyle l. Acta Paediatr. 2024 Mar;113(3):394-402. doi: 10.1111/apa.17093. Epub 2024 Jan 12. Acta Paediatr. 2024. PMID: 38214373 Review.
Deep learning uncertainty quantification for clinical text classification.
Peluso A, Danciu I, Yoon HJ, Yusof JM, Bhattacharya T, Spannaus A, Schaefferkoetter N, Durbin EB, Wu XC, Stroup A, Doherty J, Schwartz S, Wiggins C, Coyle L, Penberthy L, Tourassi GD, Gao S. Peluso A, et al. Among authors: coyle l. J Biomed Inform. 2024 Jan;149:104576. doi: 10.1016/j.jbi.2023.104576. Epub 2023 Dec 13. J Biomed Inform. 2024. PMID: 38101690 Free PMC article.
A dynamic model of the intestinal epithelium integrates multiple sources of preclinical data and enables clinical translation of drug-induced toxicity.
Gall L, Jardi F, Lammens L, Piñero J, Souza TM, Rodrigues D, Jennen DGJ, de Kok TM, Coyle L, Chung SW, Ferreira S, Jo H, Beattie KA, Kelly C, Duckworth CA, Pritchard DM, Pin C. Gall L, et al. Among authors: coyle l. CPT Pharmacometrics Syst Pharmacol. 2023 Oct;12(10):1511-1528. doi: 10.1002/psp4.13029. Epub 2023 Sep 11. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 37621010 Free PMC article.
Nonclinical pharmacokinetics and biodistribution of VSV-GP using methods to decouple input drug disposition and viral replication.
Dambra R, Matter A, Graca K, Akhand SS, Mehta S, Bell-Cohn A, Swenson JM, Abid S, Xin D, Lewis C, Coyle L, Wang M, Bunosso K, Maugiri M, Ruiz R, Cirillo CM, Fogal B, Grimaldi C, Vigil A, Wood C, Ashour J. Dambra R, et al. Among authors: coyle l. Mol Ther Methods Clin Dev. 2022 Dec 28;28:190-207. doi: 10.1016/j.omtm.2022.12.013. eCollection 2023 Mar 9. Mol Ther Methods Clin Dev. 2022. PMID: 36700123 Free PMC article.
Using ensembles and distillation to optimize the deployment of deep learning models for the classification of electronic cancer pathology reports.
De Angeli K, Gao S, Blanchard A, Durbin EB, Wu XC, Stroup A, Doherty J, Schwartz SM, Wiggins C, Coyle L, Penberthy L, Tourassi G, Yoon HJ. De Angeli K, et al. Among authors: coyle l. JAMIA Open. 2022 Sep 13;5(3):ooac075. doi: 10.1093/jamiaopen/ooac075. eCollection 2022 Oct. JAMIA Open. 2022. PMID: 36110150 Free PMC article.
Effect of Empagliflozin on Kidney Biochemical and Imaging Outcomes in Patients With Type 2 Diabetes, or Prediabetes, and Heart Failure with Reduced Ejection Fraction (SUGAR-DM-HF).
Lee MMY, Gillis KA, Brooksbank KJM, Allwood-Spiers S, Hall Barrientos P, Wetherall K, Roditi G, AlHummiany B, Berry C, Campbell RT, Chong V, Coyle L, Docherty KF, Dreisbach JG, Kuehn B, Labinjoh C, Lang NN, Lennie V, Mangion K, McConnachie A, Murphy CL, Petrie CJ, Petrie JR, Sharma K, Sourbron S, Speirits IA, Thompson J, Welsh P, Woodward R, Wright A, Radjenovic A, McMurray JJV, Jhund PS, Petrie MC, Sattar N, Mark PB. Lee MMY, et al. Among authors: coyle l. Circulation. 2022 Jul 26;146(4):364-367. doi: 10.1161/CIRCULATIONAHA.122.059851. Epub 2022 Jul 25. Circulation. 2022. PMID: 35877829 Free article. No abstract available.
Automatic information extraction from childhood cancer pathology reports.
Yoon HJ, Peluso A, Durbin EB, Wu XC, Stroup A, Doherty J, Schwartz S, Wiggins C, Coyle L, Penberthy L. Yoon HJ, et al. Among authors: coyle l. JAMIA Open. 2022 Jun 16;5(2):ooac049. doi: 10.1093/jamiaopen/ooac049. eCollection 2022 Jul. JAMIA Open. 2022. PMID: 35721398 Free PMC article.
A Keyword-Enhanced Approach to Handle Class Imbalance in Clinical Text Classification.
Blanchard AE, Gao S, Yoon HJ, Christian JB, Durbin EB, Wu XC, Stroup A, Doherty J, Schwartz SM, Wiggins C, Coyle L, Penberthy L, Tourassi GD. Blanchard AE, et al. Among authors: coyle l. IEEE J Biomed Health Inform. 2022 Jun;26(6):2796-2803. doi: 10.1109/JBHI.2022.3141976. Epub 2022 Jun 3. IEEE J Biomed Health Inform. 2022. PMID: 35020599 Free PMC article.
Class imbalance in out-of-distribution datasets: Improving the robustness of the TextCNN for the classification of rare cancer types.
De Angeli K, Gao S, Danciu I, Durbin EB, Wu XC, Stroup A, Doherty J, Schwartz S, Wiggins C, Damesyn M, Coyle L, Penberthy L, Tourassi GD, Yoon HJ. De Angeli K, et al. Among authors: coyle l. J Biomed Inform. 2022 Jan;125:103957. doi: 10.1016/j.jbi.2021.103957. Epub 2021 Nov 22. J Biomed Inform. 2022. PMID: 34823030 Free PMC article.
Privacy-Preserving Deep Learning NLP Models for Cancer Registries.
Alawad M, Yoon HJ, Gao S, Mumphrey B, Wu XC, Durbin EB, Jeong JC, Hands I, Rust D, Coyle L, Penberthy L, Tourassi G. Alawad M, et al. Among authors: coyle l. IEEE Trans Emerg Top Comput. 2021 Jul-Sep;9(3):1219-1230. doi: 10.1109/tetc.2020.2983404. Epub 2020 Apr 16. IEEE Trans Emerg Top Comput. 2021. PMID: 36117774 Free PMC article.
New insights into the mechanisms underlying 5-fluorouracil-induced intestinal toxicity based on transcriptomic and metabolomic responses in human intestinal organoids.
Rodrigues D, de Souza T, Coyle L, Di Piazza M, Herpers B, Ferreira S, Zhang M, Vappiani J, Sévin DC, Gabor A, Lynch A, Chung SW, Saez-Rodriguez J, Jennen DGJ, Kleinjans JCS, de Kok TM. Rodrigues D, et al. Among authors: coyle l. Arch Toxicol. 2021 Aug;95(8):2691-2718. doi: 10.1007/s00204-021-03092-2. Epub 2021 Jun 20. Arch Toxicol. 2021. PMID: 34151400 Free PMC article.
Deep active learning for classifying cancer pathology reports.
De Angeli K, Gao S, Alawad M, Yoon HJ, Schaefferkoetter N, Wu XC, Durbin EB, Doherty J, Stroup A, Coyle L, Penberthy L, Tourassi G. De Angeli K, et al. Among authors: coyle l. BMC Bioinformatics. 2021 Mar 9;22(1):113. doi: 10.1186/s12859-021-04047-1. BMC Bioinformatics. 2021. PMID: 33750288 Free PMC article.
Limitations of Transformers on Clinical Text Classification.
Gao S, Alawad M, Young MT, Gounley J, Schaefferkoetter N, Yoon HJ, Wu XC, Durbin EB, Doherty J, Stroup A, Coyle L, Tourassi G. Gao S, et al. Among authors: coyle l. IEEE J Biomed Health Inform. 2021 Sep;25(9):3596-3607. doi: 10.1109/JBHI.2021.3062322. Epub 2021 Sep 3. IEEE J Biomed Health Inform. 2021. PMID: 33635801 Free PMC article.
Effect of Empagliflozin on Left Ventricular Volumes in Patients With Type 2 Diabetes, or Prediabetes, and Heart Failure With Reduced Ejection Fraction (SUGAR-DM-HF).
Lee MMY, Brooksbank KJM, Wetherall K, Mangion K, Roditi G, Campbell RT, Berry C, Chong V, Coyle L, Docherty KF, Dreisbach JG, Labinjoh C, Lang NN, Lennie V, McConnachie A, Murphy CL, Petrie CJ, Petrie JR, Speirits IA, Sourbron S, Welsh P, Woodward R, Radjenovic A, Mark PB, McMurray JJV, Jhund PS, Petrie MC, Sattar N. Lee MMY, et al. Among authors: coyle l. Circulation. 2021 Feb 9;143(6):516-525. doi: 10.1161/CIRCULATIONAHA.120.052186. Epub 2020 Nov 13. Circulation. 2021. PMID: 33186500 Free PMC article. Clinical Trial.
Using case-level context to classify cancer pathology reports.
Gao S, Alawad M, Schaefferkoetter N, Penberthy L, Wu XC, Durbin EB, Coyle L, Ramanathan A, Tourassi G. Gao S, et al. Among authors: coyle l. PLoS One. 2020 May 12;15(5):e0232840. doi: 10.1371/journal.pone.0232840. eCollection 2020. PLoS One. 2020. PMID: 32396579 Free PMC article.
Generation and evaluation of synthetic patient data.
Goncalves A, Ray P, Soper B, Stevens J, Coyle L, Sales AP. Goncalves A, et al. Among authors: coyle l. BMC Med Res Methodol. 2020 May 7;20(1):108. doi: 10.1186/s12874-020-00977-1. BMC Med Res Methodol. 2020. PMID: 32381039 Free PMC article.
Classifying cancer pathology reports with hierarchical self-attention networks.
Gao S, Qiu JX, Alawad M, Hinkle JD, Schaefferkoetter N, Yoon HJ, Christian B, Fearn PA, Penberthy L, Wu XC, Coyle L, Tourassi G, Ramanathan A. Gao S, et al. Among authors: coyle l. Artif Intell Med. 2019 Nov;101:101726. doi: 10.1016/j.artmed.2019.101726. Epub 2019 Oct 15. Artif Intell Med. 2019. PMID: 31813492 Free article.
Validation of prostate-specific antigen laboratory values recorded in Surveillance, Epidemiology, and End Results registries.
National Cancer Institute Surveillance, Epidemiology, and End Results Prostate-Specific Antigen Working Group; Adamo MP, Boten JA, Coyle LM, Cronin KA, Lam CJ, Negoita S, Penberthy L, Stevens JL, Ward KC. National Cancer Institute Surveillance, Epidemiology, and End Results Prostate-Specific Antigen Working Group, et al. Among authors: coyle lm. Cancer. 2017 Feb 15;123(4):697-703. doi: 10.1002/cncr.30401. Epub 2016 Oct 26. Cancer. 2017. PMID: 27783399 Free PMC article.
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