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Page 1
Outcomes of stage I/II follicular lymphoma in the PET era: an international study from the Australian Lymphoma Alliance.
Tobin JWD, Rule G, Colvin K, Calvente L, Hodgson D, Bell S, Dunduru C, Gallo J, Tsang ES, Tan X, Wong J, Pearce J, Campbell R, Tneh S, Shorten S, Ng M, Cochrane T, Tam CS, Abro E, Hawkes E, Hodges G, Kansara R, Talaulikar D, Gilbertson M, Johnston AM, Savage KJ, Villa D, Morris K, Ratnasingam S, Janowski W, Kridel R, Cheah CY, MacManus M, Matigian N, Mollee P, Gandhi MK, Hapgood G. Tobin JWD, et al. Among authors: gandhi mk. Blood Adv. 2019 Oct 8;3(19):2804-2811. doi: 10.1182/bloodadvances.2019000458. Blood Adv. 2019. PMID: 31570492 Free PMC article.
Follicular lymphoma: time for a re-think?
Gandhi MK, Marcus RE. Gandhi MK, et al. Blood Rev. 2005 May;19(3):165-78. doi: 10.1016/j.blre.2004.09.001. Blood Rev. 2005. PMID: 15748964 Review.
Noninvasive monitoring of diffuse large B-cell lymphoma by immunoglobulin high-throughput sequencing.
Kurtz DM, Green MR, Bratman SV, Scherer F, Liu CL, Kunder CA, Takahashi K, Glover C, Keane C, Kihira S, Visser B, Callahan J, Kong KA, Faham M, Corbelli KS, Miklos D, Advani RH, Levy R, Hicks RJ, Hertzberg M, Ohgami RS, Gandhi MK, Diehn M, Alizadeh AA. Kurtz DM, et al. Among authors: gandhi mk. Blood. 2015 Jun 11;125(24):3679-87. doi: 10.1182/blood-2015-03-635169. Epub 2015 Apr 17. Blood. 2015. PMID: 25887775 Free PMC article.
Ratios of T-cell immune effectors and checkpoint molecules as prognostic biomarkers in diffuse large B-cell lymphoma: a population-based study.
Keane C, Vari F, Hertzberg M, Cao KA, Green MR, Han E, Seymour JF, Hicks RJ, Gill D, Crooks P, Gould C, Jones K, Griffiths LR, Talaulikar D, Jain S, Tobin J, Gandhi MK. Keane C, et al. Among authors: gandhi mk. Lancet Haematol. 2015 Oct;2(10):e445-55. doi: 10.1016/S2352-3026(15)00150-7. Epub 2015 Oct 1. Lancet Haematol. 2015. PMID: 26686046 Clinical Trial.
The T-cell Receptor Repertoire Influences the Tumor Microenvironment and Is Associated with Survival in Aggressive B-cell Lymphoma.
Keane C, Gould C, Jones K, Hamm D, Talaulikar D, Ellis J, Vari F, Birch S, Han E, Wood P, Le-Cao KA, Green MR, Crooks P, Jain S, Tobin J, Steptoe RJ, Gandhi MK. Keane C, et al. Among authors: gandhi mk. Clin Cancer Res. 2017 Apr 1;23(7):1820-1828. doi: 10.1158/1078-0432.CCR-16-1576. Epub 2016 Sep 20. Clin Cancer Res. 2017. PMID: 27649554
Early treatment intensification with R-ICE and 90Y-ibritumomab tiuxetan (Zevalin)-BEAM stem cell transplantation in patients with high-risk diffuse large B-cell lymphoma patients and positive interim PET after 4 cycles of R-CHOP-14.
Hertzberg M, Gandhi MK, Trotman J, Butcher B, Taper J, Johnston A, Gill D, Ho SJ, Cull G, Fay K, Chong G, Grigg A, Lewis ID, Milliken S, Renwick W, Hahn U, Filshie R, Kannourakis G, Watson AM, Warburton P, Wirth A, Seymour JF, Hofman MS, Hicks RJ; Australasian Leukaemia Lymphoma Group (ALLG). Hertzberg M, et al. Among authors: gandhi mk. Haematologica. 2017 Feb;102(2):356-363. doi: 10.3324/haematol.2016.154039. Epub 2016 Nov 10. Haematologica. 2017. PMID: 28143954 Free PMC article. Clinical Trial.
Circulating cell-free miR-494 and miR-21 are disease response biomarkers associated with interim-positron emission tomography response in patients with diffuse large B-cell lymphoma.
Cui Q, Vari F, Cristino AS, Salomon C, Rice GE, Sabdia MB, Guanzon D, Palma C, Mathew M, Talaulikar D, Jain S, Han E, Hertzberg MS, Gould C, Crooks P, Thillaiyampalam G, Keane C, Gandhi MK. Cui Q, et al. Among authors: gandhi mk. Oncotarget. 2018 Oct 5;9(78):34644-34657. doi: 10.18632/oncotarget.26141. eCollection 2018 Oct 5. Oncotarget. 2018. PMID: 30410665 Free PMC article.
The tumour microenvironment is immuno-tolerogenic and a principal determinant of patient outcome in EBV-positive diffuse large B-cell lymphoma.
Keane C, Tobin J, Gunawardana J, Francis S, Gifford G, Gabrielli S, Gill A, Stevenson W, Talaulikar D, Gould C, Jain S, Birch S, Hertzberg M, Gandhi MK. Keane C, et al. Among authors: gandhi mk. Eur J Haematol. 2019 Sep;103(3):200-207. doi: 10.1111/ejh.13274. Epub 2019 Jul 24. Eur J Haematol. 2019. PMID: 31211907 Free PMC article.
COO and MYC/BCL2 status do not predict outcome among patients with stage I/II DLBCL: a retrospective multicenter study.
Barraclough A, Alzahrani M, Ettrup MS, Bishton M, van Vliet C, Farinha P, Gould C, Birch S, Sehn LH, Sovani V, Ward MS, Augustson B, Biccler J, Connors JM, Scott DW, Gandhi MK, Savage KJ, El-Galaly T, Villa D, Cheah CY. Barraclough A, et al. Among authors: gandhi mk. Blood Adv. 2019 Jul 9;3(13):2013-2021. doi: 10.1182/bloodadvances.2019000251. Blood Adv. 2019. PMID: 31285189 Free PMC article.
Progression of Disease Within 24 Months in Follicular Lymphoma Is Associated With Reduced Intratumoral Immune Infiltration.
Tobin JWD, Keane C, Gunawardana J, Mollee P, Birch S, Hoang T, Lee J, Li L, Huang L, Murigneux V, Fink JL, Matigian N, Vari F, Francis S, Kridel R, Weigert O, Haebe S, Jurinovic V, Klapper W, Steidl C, Sehn LH, Law SC, Wykes MN, Gandhi MK. Tobin JWD, et al. Among authors: gandhi mk. J Clin Oncol. 2019 Dec 1;37(34):3300-3309. doi: 10.1200/JCO.18.02365. Epub 2019 Aug 28. J Clin Oncol. 2019. PMID: 31461379 Free PMC article.
Reply to M. Sorigue.
Tobin JWD, Keane C, Gunawardana J, Gandhi MK. Tobin JWD, et al. Among authors: gandhi mk. J Clin Oncol. 2020 Feb 20;38(6):648-649. doi: 10.1200/JCO.19.02935. Epub 2019 Dec 9. J Clin Oncol. 2020. PMID: 31815583 No abstract available.
LAG3: a novel immune checkpoint expressed by multiple lymphocyte subsets in diffuse large B-cell lymphoma.
Keane C, Law SC, Gould C, Birch S, Sabdia MB, Merida de Long L, Thillaiyampalam G, Abro E, Tobin JW, Tan X, Xu-Monette ZY, Young KH, Gifford G, Gabreilli S, Stevenson WS, Gill A, Talaulikar D, Jain S, Hernandez A, Halliday SJ, Bird R, Cross D, Hertzberg M, Gandhi MK. Keane C, et al. Among authors: gandhi mk. Blood Adv. 2020 Apr 14;4(7):1367-1377. doi: 10.1182/bloodadvances.2019001390. Blood Adv. 2020. PMID: 32267932 Free PMC article.
Cathepsin S Alterations Induce a Tumor-Promoting Immune Microenvironment in Follicular Lymphoma.
Bararia D, Hildebrand JA, Stolz S, Haebe S, Alig S, Trevisani CP, Osorio-Barrios F, Bartoschek MD, Mentz M, Pastore A, Gaitzsch E, Heide M, Jurinovic V, Rautter K, Gunawardana J, Sabdia MB, Szczepanowski M, Richter J, Klapper W, Louissaint A Jr, Ludwig C, Bultmann S, Leonhardt H, Eustermann S, Hopfner KP, Hiddemann W, von Bergwelt-Baildon M, Steidl C, Kridel R, Tobin JWD, Gandhi MK, Weinstock DM, Schmidt-Supprian M, Sárosi MB, Rudelius M, Passerini V, Mautner J, Weigert O. Bararia D, et al. Among authors: gandhi mk. Cell Rep. 2020 May 5;31(5):107522. doi: 10.1016/j.celrep.2020.107522. Epub 2020 Apr 23. Cell Rep. 2020. PMID: 32330423 Free article.
EBV-associated primary CNS lymphoma occurring after immunosuppression is a distinct immunobiological entity.
Gandhi MK, Hoang T, Law SC, Brosda S, O'Rourke K, Tobin JWD, Vari F, Murigneux V, Fink L, Gunawardana J, Gould C, Oey H, Bednarska K, Delecluse S, Trappe RU, Merida de Long L, Sabdia MB, Bhagat G, Hapgood G, Blyth E, Clancy L, Wight J, Hawkes E, Rimsza LM, Maguire A, Bojarczuk K, Chapuy B, Keane C. Gandhi MK, et al. Blood. 2021 Mar 18;137(11):1468-1477. doi: 10.1182/blood.2020008520. Blood. 2021. PMID: 33202420 Free PMC article.
Successful treatment of Epstein-Barr virus-associated primary central nervous system lymphoma due to post-transplantation lymphoproliferative disorder, with ibrutinib and third-party Epstein-Barr virus-specific T cells.
Law SC, Hoang T, O'Rourke K, Tobin JWD, Gunawardana J, Loo-Oey D, Bednarska K, Merida de Long L, Sabdia MB, Hapgood G, Blyth E, Clancy L, Hennig S, Keane C, Gandhi MK. Law SC, et al. Among authors: gandhi mk. Am J Transplant. 2021 Oct;21(10):3465-3471. doi: 10.1111/ajt.16628. Epub 2021 Jun 11. Am J Transplant. 2021. PMID: 33942495 Free article.
Discordant solutions to discordant problems.
Tobin JWD, Gandhi MK. Tobin JWD, et al. Among authors: gandhi mk. Blood. 2021 May 27;137(21):2857-2858. doi: 10.1182/blood.2021011362. Blood. 2021. PMID: 34042983 Free article. No abstract available.
Intratumoral T cells have a differential impact on FDG-PET parameters in follicular lymphoma.
Nath K, Law SC, Sabdia MB, Gunawardana J, de Long LM, Sester D, Shanavas M, Tsang H, Tobin JWD, Halliday SJ, Hernandez A, Cross D, Bird RJ, Jain S, Keane C, Talaulikar D, Trotman J, Law P, Gandhi MK. Nath K, et al. Among authors: gandhi mk. Blood Adv. 2021 Jun 22;5(12):2644-2649. doi: 10.1182/bloodadvances.2020004051. Blood Adv. 2021. PMID: 34156439 Free PMC article.
Characterisation of immune checkpoints in Richter syndrome identifies LAG3 as a potential therapeutic target.
Gould C, Lickiss J, Kankanige Y, Yerneni S, Lade S, Gandhi MK, Chin C, Yannakou CK, Villa D, Slack GW, Markham JF, Tam CS, Nelson N, Seymour JF, Dickinson M, Neeson PJ, Westerman D, Blombery P. Gould C, et al. Among authors: gandhi mk. Br J Haematol. 2021 Oct;195(1):113-118. doi: 10.1111/bjh.17789. Epub 2021 Aug 23. Br J Haematol. 2021. PMID: 34426978
The PO4-tential for Less Toxic CAR T-cell Therapies.
Tobin JWD, Green MR, Gandhi MK. Tobin JWD, et al. Among authors: gandhi mk. Cancer Immunol Res. 2022 Dec 2;10(12):1422. doi: 10.1158/2326-6066.CIR-22-0793. Cancer Immunol Res. 2022. PMID: 36327248
Epstein-Barr virus-associated lymphomas decoded.
Bednarska K, Chowdhury R, Tobin JWD, Swain F, Keane C, Boyle S, Khanna R, Gandhi MK. Bednarska K, et al. Among authors: gandhi mk. Br J Haematol. 2024 Feb;204(2):415-433. doi: 10.1111/bjh.19255. Epub 2023 Dec 28. Br J Haematol. 2024. PMID: 38155519 Review.
Single gene mutations and prognosis in limited-stage follicular lymphoma treated with radiation therapy.
Hershenfeld SA, Tobin JWD, Shelton V, Calvente L, Lajkosz K, Liu T, Brodtkorb M, d'Amore FA, Ludvigsen M, Baetz T, LeBrun D, Johnson N, Crump M, Hong M, Kuruvilla J, Tremblay-LeMay R, MacManus M, Tsang R, Hodgson DC, Gandhi MK, Kridel R. Hershenfeld SA, et al. Among authors: gandhi mk. Br J Haematol. 2024 Nov;205(5):1810-1814. doi: 10.1111/bjh.19698. Epub 2024 Aug 7. Br J Haematol. 2024. PMID: 39112220
Identification of genetic subtypes in follicular lymphoma.
Shelton V, Detroja R, Liu T, Isaev K, Silva A, Passerini V, Bakhtiari M, Calvente L, Hong M, He MY, Modi S, Hershenfeld SA, Ludvigsen M, Madsen C, Hamilton-Dutoit S, d'Amore FA, Brodtkorb M, Johnson NA, Baetz T, LeBrun D, Tobin JWD, Gandhi MK, Mungall AJ, Xu W, Ben-Neriah S, Steidl C, Delabie J, Tremblay-LeMay R, Jegede O, Weigert O, Kahl B, Evens AM, Kridel R. Shelton V, et al. Among authors: gandhi mk. Blood Cancer J. 2024 Aug 7;14(1):128. doi: 10.1038/s41408-024-01111-w. Blood Cancer J. 2024. PMID: 39112453 Free PMC article.
Intra-tumoral and peripheral blood TIGIT and PD-1 as immune biomarkers in nodular lymphocyte predominant Hodgkin lymphoma.
Gunawardana J, Law SC, Sabdia MB, Fennell É, Hennessy A, Leahy CI, Murray PG, Bednarska K, Brosda S, Trotman J, Berkahn L, Zaharia A, Birch S, Burgess M, Talaulikar D, Lee JN, Jude E, Hawkes EA, Jain S, Nath K, Snell C, Swain F, Tobin JWD, Keane C, Shanavas M, Blyth E, Steidl C, Savage K, Farinha P, Boyle M, Meissner B, Green MR, Vega F, Gandhi MK. Gunawardana J, et al. Among authors: gandhi mk. Am J Hematol. 2024 Nov;99(11):2096-2107. doi: 10.1002/ajh.27459. Epub 2024 Aug 17. Am J Hematol. 2024. PMID: 39152767
Ibrutinib plus rituximab and mini-CHOP in older patients with newly diagnosed DLBCL: a phase 2 ALLG study.
Verner E, Johnston A, Pati N, Hawkes EA, Lee HP, Cochrane T, Cheah CY, Filshie R, Purtill D, Sia H, Enjeti AK, Brown C, Murphy N, Curnow J, Lee K, Gandhi MK, Walia M, Butcher BE, Trotman J. Verner E, et al. Among authors: gandhi mk. Blood Adv. 2024 Nov 12;8(21):5674-5682. doi: 10.1182/bloodadvances.2024014035. Blood Adv. 2024. PMID: 39226464 Free PMC article. Clinical Trial.
Adjuvant rituximab and elevated intratumoural CD8 expression are associated with sustained disease control after radiotherapy in a randomised trial of systemic therapy in early-stage follicular lymphoma.
MacManus MP, Seymour JF, Tsang H, Fisher R, Keane C, Sabdia MB, Law SC, Gunawardana J, Nath K, Kazakoff SH, Marques-Piubelli ML, Duenas DE, Green MR, Roos D, O'Brien P, McCann A, Tsang R, Davis S, Christie D, Cheah C, Amanuel B, Cochrane T, Butler J, Johnston A, Shanavas M, Li L, Vajdic C, Kridel R, Shelton V, Hershenfield S, Baetz T, Lebrun D, Johnson N, Brodtkorb M, Ludvigsen M, d'Amore F, Thompson ER, Blombery P, Gandhi MK, Tobin JWD. MacManus MP, et al. Among authors: gandhi mk. EBioMedicine. 2024 Dec;110:105468. doi: 10.1016/j.ebiom.2024.105468. Epub 2024 Dec 3. EBioMedicine. 2024. PMID: 39631145 Free PMC article. Clinical Trial.
Epstein-Barr virus T-cell immunity despite rituximab.
Nehring AK, Dua U, Mollee P, Gill D, Grimmett K, Khanna R, Moss D, Gandhi MK. Nehring AK, et al. Among authors: gandhi mk. Br J Haematol. 2007 Feb;136(4):628-32. doi: 10.1111/j.1365-2141.2006.06482.x. Br J Haematol. 2007. PMID: 17223914 Free article. Clinical Trial.
Targeted Treatment of Follicular Lymphoma.
Nath K, Gandhi MK. Nath K, et al. Among authors: gandhi mk. J Pers Med. 2021 Feb 22;11(2):152. doi: 10.3390/jpm11020152. J Pers Med. 2021. PMID: 33671658 Free PMC article. Review.
Genetic susceptibility to EBV-related disease.
Gandhi MK. Gandhi MK. Blood. 2023 Mar 30;141(13):1499-1500. doi: 10.1182/blood.2022019180. Blood. 2023. PMID: 36995704 Free article. No abstract available.
EBV-infected hematopoietic stem cells drive CAEBV.
Khanna R, Gandhi MK. Khanna R, et al. Among authors: gandhi mk. Blood. 2024 Jan 4;143(1):2-4. doi: 10.1182/blood.2023022739. Blood. 2024. PMID: 38175680 Free article. No abstract available.
Immunodeficiency-associated lymphomas.
Tran H, Nourse J, Hall S, Green M, Griffiths L, Gandhi MK. Tran H, et al. Among authors: gandhi mk. Blood Rev. 2008 Sep;22(5):261-81. doi: 10.1016/j.blre.2008.03.009. Epub 2008 May 5. Blood Rev. 2008. PMID: 18456377 Review.
Subtype-specific and co-occurring genetic alterations in B-cell non-Hodgkin lymphoma.
Ma MCJ, Tadros S, Bouska A, Heavican T, Yang H, Deng Q, Moore D, Akhter A, Hartert K, Jain N, Showell J, Ghosh S, Street L, Davidson M, Carey C, Tobin J, Perumal D, Vose JM, Lunning MA, Sohani AR, Chen BJ, Buckley S, Nastoupil LJ, Davis RE, Westin JR, Fowler NH, Parekh S, Gandhi M, Neelapu S, Stewart D, Bhalla K, Iqbal J, Greiner T, Rodig SJ, Mansoor A, Green MR. Ma MCJ, et al. Haematologica. 2022 Mar 1;107(3):690-701. doi: 10.3324/haematol.2020.274258. Haematologica. 2022. PMID: 33792219 Free PMC article.
Intratumoral T-cell receptor repertoire is predictive of interim PET scan results in patients with diffuse large B-cell lymphoma treated with rituximab/cyclophosphamide/doxorubicin/prednisolone/vincristine (R-CHOP) chemoimmunotherapy.
Shanavas M, Law SC, Hertzberg M, Hicks RJ, Seymour JF, Li Z, Merida de Long L, Nath K, Sabdia MB, Gunawardana J, Gandhi MK, Keane C. Shanavas M, et al. Among authors: gandhi mk. Clin Transl Immunology. 2021 Oct 27;10(11):e1351. doi: 10.1002/cti2.1351. eCollection 2021. Clin Transl Immunology. 2021. PMID: 34745610 Free PMC article.
Genome-wide transcription factor-binding maps reveal cell-specific changes in the regulatory architecture of human HSPCs.
Subramanian S, Thoms JAI, Huang Y, Cornejo-Páramo P, Koch FC, Jacquelin S, Shen S, Song E, Joshi S, Brownlee C, Woll PS, Chacon-Fajardo D, Beck D, Curtis DJ, Yehson K, Antonenas V, O'Brien T, Trickett A, Powell JA, Lewis ID, Pitson SM, Gandhi MK, Lane SW, Vafaee F, Wong ES, Göttgens B, Alinejad-Rokny H, Wong JWH, Pimanda JE. Subramanian S, et al. Among authors: gandhi mk. Blood. 2023 Oct 26;142(17):1448-1462. doi: 10.1182/blood.2023021120. Blood. 2023. PMID: 37595278 Free PMC article.
High-resolution loss of heterozygosity screening implicates PTPRJ as a potential tumor suppressor gene that affects susceptibility to Non-Hodgkin's lymphoma.
Aya-Bonilla C, Green MR, Camilleri E, Benton M, Keane C, Marlton P, Lea R, Gandhi MK, Griffiths LR. Aya-Bonilla C, et al. Among authors: gandhi mk. Genes Chromosomes Cancer. 2013 May;52(5):467-79. doi: 10.1002/gcc.22044. Epub 2013 Jan 23. Genes Chromosomes Cancer. 2013. PMID: 23341091 Free article.
Viruses and lymphoma.
Gandhi MK, Khanna R. Gandhi MK, et al. Pathology. 2005 Dec;37(6):420-33. doi: 10.1080/003130200500368303. Pathology. 2005. PMID: 16373225 Review.
A multi-centre, single-arm, open-label study evaluating the safety and efficacy of fixed dose rituximab in patients with refractory, relapsed or chronic idiopathic thrombocytopenic purpura (R-ITP1000 study).
Tran H, Brighton T, Grigg A, McRae S, Dixon J, Thurley D, Gandhi MK, Truman M, Marlton P, Catalano J. Tran H, et al. Among authors: gandhi mk. Br J Haematol. 2014 Oct;167(2):243-51. doi: 10.1111/bjh.13029. Epub 2014 Jul 11. Br J Haematol. 2014. PMID: 25041261 Free article. Clinical Trial.
Allogeneic cytotoxic T-cell therapy for EBV-positive posttransplantation lymphoproliferative disease: results of a phase 2 multicenter clinical trial.
Haque T, Wilkie GM, Jones MM, Higgins CD, Urquhart G, Wingate P, Burns D, McAulay K, Turner M, Bellamy C, Amlot PL, Kelly D, MacGilchrist A, Gandhi MK, Swerdlow AJ, Crawford DH. Haque T, et al. Among authors: gandhi mk. Blood. 2007 Aug 15;110(4):1123-31. doi: 10.1182/blood-2006-12-063008. Epub 2007 Apr 27. Blood. 2007. PMID: 17468341 Free article. Clinical Trial.
The impact of HLA class I and EBV latency-II antigen-specific CD8(+) T cells on the pathogenesis of EBV(+) Hodgkin lymphoma.
Jones K, Wockner L, Brennan RM, Keane C, Chattopadhyay PK, Roederer M, Price DA, Cole DK, Hassan B, Beck K, Gottlieb D, Ritchie DS, Seymour JF, Vari F, Crooks P, Burrows SR, Gandhi MK. Jones K, et al. Among authors: gandhi mk. Clin Exp Immunol. 2016 Feb;183(2):206-20. doi: 10.1111/cei.12716. Epub 2015 Nov 13. Clin Exp Immunol. 2016. PMID: 26422112 Free PMC article.
Epstein-Barr virus-associated Hodgkin's lymphoma.
Gandhi MK, Tellam JT, Khanna R. Gandhi MK, et al. Br J Haematol. 2004 May;125(3):267-81. doi: 10.1111/j.1365-2141.2004.04902.x. Br J Haematol. 2004. PMID: 15086409 Free article. Review.
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