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Page 1
The oncogene c-Jun impedes somatic cell reprogramming.
Liu J, Han Q, Peng T, Peng M, Wei B, Li D, Wang X, Yu S, Yang J, Cao S, Huang K, Hutchins AP, Liu H, Kuang J, Zhou Z, Chen J, Wu H, Guo L, Chen Y, Chen Y, Li X, Wu H, Liao B, He W, Song H, Yao H, Pan G, Chen J, Pei D. Liu J, et al. Among authors: pei d. Nat Cell Biol. 2015 Jul;17(7):856-67. doi: 10.1038/ncb3193. Epub 2015 Jun 22. Nat Cell Biol. 2015. PMID: 26098572
Shedding of membrane type matrix metalloproteinase 5 by a furin-type convertase: a potential mechanism for down-regulation.
Wang X, Pei D. Wang X, et al. Among authors: pei d. J Biol Chem. 2001 Sep 21;276(38):35953-60. doi: 10.1074/jbc.M103680200. Epub 2001 Jul 26. J Biol Chem. 2001. PMID: 11470782 Free article.
We have reported previously that the ectoenzyme of membrane type matrix metalloproteinase 5 (MT5-MMP) is shed into extracellular milieu (Pei, D. (1999) J. Biol. Chem. 274, 8925-8932). Here we present evidence that MT5-MMP is shed by a furin-type convertase activity …
We have reported previously that the ectoenzyme of membrane type matrix metalloproteinase 5 (MT5-MMP) is shed into extracellular milieu ( …
Regulation of the pluripotency marker Rex-1 by Nanog and Sox2.
Shi W, Wang H, Pan G, Geng Y, Guo Y, Pei D. Shi W, et al. Among authors: pei d. J Biol Chem. 2006 Aug 18;281(33):23319-25. doi: 10.1074/jbc.M601811200. Epub 2006 May 21. J Biol Chem. 2006. PMID: 16714766 Free article.
The magic continues for the iPS strategy.
Pei D. Pei D. Cell Res. 2008 Feb;18(2):221-3. doi: 10.1038/cr.2008.21. Cell Res. 2008. PMID: 18246087 Review. No abstract available.
Generation of induced pluripotent stem cell lines from Tibetan miniature pig.
Esteban MA, Xu J, Yang J, Peng M, Qin D, Li W, Jiang Z, Chen J, Deng K, Zhong M, Cai J, Lai L, Pei D. Esteban MA, et al. Among authors: pei d. J Biol Chem. 2009 Jun 26;284(26):17634-40. doi: 10.1074/jbc.M109.008938. Epub 2009 Apr 17. J Biol Chem. 2009. PMID: 19376775 Free PMC article.
Vitamin C enhances the generation of mouse and human induced pluripotent stem cells.
Esteban MA, Wang T, Qin B, Yang J, Qin D, Cai J, Li W, Weng Z, Chen J, Ni S, Chen K, Li Y, Liu X, Xu J, Zhang S, Li F, He W, Labuda K, Song Y, Peterbauer A, Wolbank S, Redl H, Zhong M, Cai D, Zeng L, Pei D. Esteban MA, et al. Among authors: pei d. Cell Stem Cell. 2010 Jan 8;6(1):71-9. doi: 10.1016/j.stem.2009.12.001. Epub 2009 Dec 31. Cell Stem Cell. 2010. PMID: 20036631 Free article.
A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts.
Li R, Liang J, Ni S, Zhou T, Qing X, Li H, He W, Chen J, Li F, Zhuang Q, Qin B, Xu J, Li W, Yang J, Gan Y, Qin D, Feng S, Song H, Yang D, Zhang B, Zeng L, Lai L, Esteban MA, Pei D. Li R, et al. Among authors: pei d. Cell Stem Cell. 2010 Jul 2;7(1):51-63. doi: 10.1016/j.stem.2010.04.014. Epub 2010 Jun 17. Cell Stem Cell. 2010. PMID: 20621050 Free article.
Generation of induced pluripotent stem cells from urine.
Zhou T, Benda C, Duzinger S, Huang Y, Li X, Li Y, Guo X, Cao G, Chen S, Hao L, Chan YC, Ng KM, Ho JC, Wieser M, Wu J, Redl H, Tse HF, Grillari J, Grillari-Voglauer R, Pei D, Esteban MA. Zhou T, et al. Among authors: pei d. J Am Soc Nephrol. 2011 Jul;22(7):1221-8. doi: 10.1681/ASN.2011010106. Epub 2011 Jun 2. J Am Soc Nephrol. 2011. PMID: 21636641 Free PMC article.
Modeling abnormal early development with induced pluripotent stem cells from aneuploid syndromes.
Li W, Wang X, Fan W, Zhao P, Chan YC, Chen S, Zhang S, Guo X, Zhang Y, Li Y, Cai J, Qin D, Li X, Yang J, Peng T, Zychlinski D, Hoffmann D, Zhang R, Deng K, Ng KM, Menten B, Zhong M, Wu J, Li Z, Chen Y, Schambach A, Tse HF, Pei D, Esteban MA. Li W, et al. Among authors: pei d. Hum Mol Genet. 2012 Jan 1;21(1):32-45. doi: 10.1093/hmg/ddr435. Epub 2011 Sep 23. Hum Mol Genet. 2012. PMID: 21949351
EMT and MET as paradigms for cell fate switching.
Chen J, Han Q, Pei D. Chen J, et al. Among authors: pei d. J Mol Cell Biol. 2012 Apr;4(2):66-9. doi: 10.1093/jmcb/mjr045. Epub 2011 Dec 2. J Mol Cell Biol. 2012. PMID: 22140271
Reprogramming in suspension.
Chen J, Pei D. Chen J, et al. Among authors: pei d. Nat Methods. 2012 Apr 27;9(5):449-51. doi: 10.1038/nmeth.1989. Nat Methods. 2012. PMID: 22543375 No abstract available.
Generation of human induced pluripotent stem cells from urine samples.
Zhou T, Benda C, Dunzinger S, Huang Y, Ho JC, Yang J, Wang Y, Zhang Y, Zhuang Q, Li Y, Bao X, Tse HF, Grillari J, Grillari-Voglauer R, Pei D, Esteban MA. Zhou T, et al. Among authors: pei d. Nat Protoc. 2012 Dec;7(12):2080-9. doi: 10.1038/nprot.2012.115. Epub 2012 Nov 8. Nat Protoc. 2012. PMID: 23138349
H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs.
Chen J, Liu H, Liu J, Qi J, Wei B, Yang J, Liang H, Chen Y, Chen J, Wu Y, Guo L, Zhu J, Zhao X, Peng T, Zhang Y, Chen S, Li X, Li D, Wang T, Pei D. Chen J, et al. Among authors: pei d. Nat Genet. 2013 Jan;45(1):34-42. doi: 10.1038/ng.2491. Epub 2012 Dec 2. Nat Genet. 2013. PMID: 23202127
MicroRNAs in somatic cell reprogramming.
Bao X, Zhu X, Liao B, Benda C, Zhuang Q, Pei D, Qin B, Esteban MA. Bao X, et al. Among authors: pei d. Curr Opin Cell Biol. 2013 Apr;25(2):208-14. doi: 10.1016/j.ceb.2012.12.004. Epub 2013 Jan 16. Curr Opin Cell Biol. 2013. PMID: 23332905 Review.
Roles of small molecules in somatic cell reprogramming.
Su JB, Pei DQ, Qin BM. Su JB, et al. Acta Pharmacol Sin. 2013 Jun;34(6):719-24. doi: 10.1038/aps.2013.73. Epub 2013 Jun 3. Acta Pharmacol Sin. 2013. PMID: 23728722 Free PMC article. Review.
Vitamin C modulates TET1 function during somatic cell reprogramming.
Chen J, Guo L, Zhang L, Wu H, Yang J, Liu H, Wang X, Hu X, Gu T, Zhou Z, Liu J, Liu J, Wu H, Mao SQ, Mo K, Li Y, Lai K, Qi J, Yao H, Pan G, Xu GL, Pei D. Chen J, et al. Among authors: pei d. Nat Genet. 2013 Dec;45(12):1504-9. doi: 10.1038/ng.2807. Epub 2013 Oct 27. Nat Genet. 2013. PMID: 24162740
Where cell fate conversions meet Chinese philosophy.
Zheng H, Hutchins AP, Pan G, Li Y, Pei D, Pei G. Zheng H, et al. Among authors: pei d, pei g. Cell Res. 2014 Oct;24(10):1162-3. doi: 10.1038/cr.2014.93. Epub 2014 Jul 15. Cell Res. 2014. PMID: 25022900 Free PMC article.
Cancer: pathological nuclear reprogramming?
Goding CR, Pei D, Lu X. Goding CR, et al. Among authors: pei d. Nat Rev Cancer. 2014 Aug;14(8):568-73. doi: 10.1038/nrc3781. Epub 2014 Jul 17. Nat Rev Cancer. 2014. PMID: 25030952 Review.
Transcriptional pause release is a rate-limiting step for somatic cell reprogramming.
Liu L, Xu Y, He M, Zhang M, Cui F, Lu L, Yao M, Tian W, Benda C, Zhuang Q, Huang Z, Li W, Li X, Zhao P, Fan W, Luo Z, Li Y, Wu Y, Hutchins AP, Wang D, Tse HF, Schambach A, Frampton J, Qin B, Bao X, Yao H, Zhang B, Sun H, Pei D, Wang H, Wang J, Esteban MA. Liu L, et al. Among authors: pei d. Cell Stem Cell. 2014 Nov 6;15(5):574-88. doi: 10.1016/j.stem.2014.09.018. Epub 2014 Oct 9. Cell Stem Cell. 2014. PMID: 25312495 Free article.
The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters.
Bao X, Wu H, Zhu X, Guo X, Hutchins AP, Luo Z, Song H, Chen Y, Lai K, Yin M, Xu L, Zhou L, Chen J, Wang D, Qin B, Frampton J, Tse HF, Pei D, Wang H, Zhang B, Esteban MA. Bao X, et al. Among authors: pei d. Cell Res. 2015 Jan;25(1):80-92. doi: 10.1038/cr.2014.165. Epub 2014 Dec 16. Cell Res. 2015. PMID: 25512341 Free PMC article.
Autophagy and mTORC1 regulate the stochastic phase of somatic cell reprogramming.
Wu Y, Li Y, Zhang H, Huang Y, Zhao P, Tang Y, Qiu X, Ying Y, Li W, Ni S, Zhang M, Liu L, Xu Y, Zhuang Q, Luo Z, Benda C, Song H, Liu B, Lai L, Liu X, Tse HF, Bao X, Chan WY, Esteban MA, Qin B, Pei D. Wu Y, et al. Among authors: pei d. Nat Cell Biol. 2015 Jun;17(6):715-25. doi: 10.1038/ncb3172. Epub 2015 May 18. Nat Cell Biol. 2015. PMID: 25985393
Loss of ATOH8 Increases Stem Cell Features of Hepatocellular Carcinoma Cells.
Song Y, Pan G, Chen L, Ma S, Zeng T, Man Chan TH, Li L, Lian Q, Chow R, Cai X, Li Y, Li Y, Liu M, Li Y, Zhu Y, Wong N, Yuan YF, Pei D, Guan XY. Song Y, et al. Among authors: pei d. Gastroenterology. 2015 Oct;149(4):1068-81.e5. doi: 10.1053/j.gastro.2015.06.010. Epub 2015 Jun 20. Gastroenterology. 2015. PMID: 26099525
GATA2(-/-) human ESCs undergo attenuated endothelial to hematopoietic transition and thereafter granulocyte commitment.
Huang K, Du J, Ma N, Liu J, Wu P, Dong X, Meng M, Wang W, Chen X, Shi X, Chen Q, Yang Z, Chen S, Zhang J, Li Y, Li W, Zheng Y, Cai J, Li P, Sun X, Wang J, Pei D, Pan G. Huang K, et al. Among authors: pei d. Cell Regen. 2015 Aug 5;4(1):4. doi: 10.1186/s13619-015-0018-7. eCollection 2015. Cell Regen. 2015. PMID: 26246892 Free PMC article.
Corrigendum: The oncogene c-Jun impedes somatic cell reprogramming.
Liu J, Han Q, Peng T, Peng M, Wei B, Li D, Wang X, Yu S, Yang J, Cao S, Huang K, Hutchins AP, Liu H, Kuang J, Zhou Z, Chen J, Wu H, Guo L, Chen Y, Chen Y, Li X, Wu H, Liao B, He W, Song H, Yao H, Pan G, Chen J, Pei D. Liu J, et al. Among authors: pei d. Nat Cell Biol. 2015 Sep;17(9):1228. doi: 10.1038/ncb3235. Nat Cell Biol. 2015. PMID: 26316456 No abstract available.
Hallmarks of pluripotency.
De Los Angeles A, Ferrari F, Xi R, Fujiwara Y, Benvenisty N, Deng H, Hochedlinger K, Jaenisch R, Lee S, Leitch HG, Lensch MW, Lujan E, Pei D, Rossant J, Wernig M, Park PJ, Daley GQ. De Los Angeles A, et al. Among authors: pei d. Nature. 2015 Sep 24;525(7570):469-78. doi: 10.1038/nature15515. Nature. 2015. PMID: 26399828 Review.
Failure to replicate the STAP cell phenomenon.
De Los Angeles A, Ferrari F, Fujiwara Y, Mathieu R, Lee S, Lee S, Tu HC, Ross S, Chou S, Nguyen M, Wu Z, Theunissen TW, Powell BE, Imsoonthornruksa S, Chen J, Borkent M, Krupalnik V, Lujan E, Wernig M, Hanna JH, Hochedlinger K, Pei D, Jaenisch R, Deng H, Orkin SH, Park PJ, Daley GQ. De Los Angeles A, et al. Among authors: pei d. Nature. 2015 Sep 24;525(7570):E6-9. doi: 10.1038/nature15513. Nature. 2015. PMID: 26399835 No abstract available.
Pluripotency without Proliferation.
Shu X, Pei D. Shu X, et al. Among authors: pei d. Cell. 2016 Feb 11;164(4):595-7. doi: 10.1016/j.cell.2016.01.050. Cell. 2016. PMID: 26871623 Free article.
Gadd45a is a heterochromatin relaxer that enhances iPS cell generation.
Chen K, Long Q, Wang T, Zhao D, Zhou Y, Qi J, Wu Y, Li S, Chen C, Zeng X, Yang J, Zhou Z, Qin W, Liu X, Li Y, Li Y, Huang X, Qin D, Chen J, Pan G, Schöler HR, Xu G, Liu X, Pei D. Chen K, et al. Among authors: pei d. EMBO Rep. 2016 Nov;17(11):1641-1656. doi: 10.15252/embr.201642402. Epub 2016 Oct 4. EMBO Rep. 2016. PMID: 27702986 Free PMC article.
Epigenetic Landmarks During Somatic Reprogramming.
Chen J, Pei D. Chen J, et al. Among authors: pei d. IUBMB Life. 2016 Nov;68(11):854-857. doi: 10.1002/iub.1577. IUBMB Life. 2016. PMID: 27785904 Free article. Review.
RNA Helicase DDX5 Inhibits Reprogramming to Pluripotency by miRNA-Based Repression of RYBP and its PRC1-Dependent and -Independent Functions.
Li H, Lai P, Jia J, Song Y, Xia Q, Huang K, He N, Ping W, Chen J, Yang Z, Li J, Yao M, Dong X, Zhao J, Hou C, Esteban MA, Gao S, Pei D, Hutchins AP, Yao H. Li H, et al. Among authors: pei d. Cell Stem Cell. 2017 Apr 6;20(4):462-477.e6. doi: 10.1016/j.stem.2016.12.002. Epub 2017 Jan 19. Cell Stem Cell. 2017. PMID: 28111200 Free article.
RNA Helicase DDX5 Inhibits Reprogramming to Pluripotency by miRNA-Based Repression of RYBP and its PRC1-Dependent and -Independent Functions.
Li H, Lai P, Jia J, Song Y, Xia Q, Huang K, He N, Ping W, Chen J, Yang Z, Li J, Yao M, Dong X, Zhao J, Hou C, Esteban MA, Gao S, Pei D, Hutchins AP, Yao H. Li H, et al. Among authors: pei d. Cell Stem Cell. 2017 Apr 6;20(4):571. doi: 10.1016/j.stem.2017.03.014. Cell Stem Cell. 2017. PMID: 28388433 Free article. No abstract available.
Chemical reprogramming of mouse embryonic and adult fibroblast into endoderm lineage.
Cao S, Yu S, Chen Y, Wang X, Zhou C, Liu Y, Kuang J, Liu H, Li D, Ye J, Qin Y, Chu S, Wu L, Guo L, Li Y, Shu X, Chen J, Liu J, Pei D. Cao S, et al. Among authors: pei d. J Biol Chem. 2017 Nov 17;292(46):19122-19132. doi: 10.1074/jbc.M117.812537. Epub 2017 Sep 21. J Biol Chem. 2017. PMID: 28935668 Free PMC article.
PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs.
Shan Y, Liang Z, Xing Q, Zhang T, Wang B, Tian S, Huang W, Zhang Y, Yao J, Zhu Y, Huang K, Liu Y, Wang X, Chen Q, Zhang J, Shang B, Li S, Shi X, Liao B, Zhang C, Lai K, Zhong X, Shu X, Wang J, Yao H, Chen J, Pei D, Pan G. Shan Y, et al. Among authors: pei d. Nat Commun. 2017 Sep 22;8(1):672. doi: 10.1038/s41467-017-00668-4. Nat Commun. 2017. PMID: 28939884 Free PMC article.
Kdm2b Regulates Somatic Reprogramming through Variant PRC1 Complex-Dependent Function.
Zhou Z, Yang X, He J, Liu J, Wu F, Yu S, Liu Y, Lin R, Liu H, Cui Y, Zhou C, Wang X, Wu J, Cao S, Guo L, Lin L, Wang T, Peng X, Qiang B, Hutchins AP, Pei D, Chen J. Zhou Z, et al. Among authors: pei d. Cell Rep. 2017 Nov 21;21(8):2160-2170. doi: 10.1016/j.celrep.2017.10.091. Cell Rep. 2017. PMID: 29166607 Free article.
Chromatin Accessibility Dynamics during iPSC Reprogramming.
Li D, Liu J, Yang X, Zhou C, Guo J, Wu C, Qin Y, Guo L, He J, Yu S, Liu H, Wang X, Wu F, Kuang J, Hutchins AP, Chen J, Pei D. Li D, et al. Among authors: pei d. Cell Stem Cell. 2017 Dec 7;21(6):819-833.e6. doi: 10.1016/j.stem.2017.10.012. Cell Stem Cell. 2017. PMID: 29220666 Free article.
Chromatin Accessibility Dynamics during Chemical Induction of Pluripotency.
Cao S, Yu S, Li D, Ye J, Yang X, Li C, Wang X, Mai Y, Qin Y, Wu J, He J, Zhou C, Liu H, Zhao B, Shu X, Wu C, Chen R, Chan W, Pan G, Chen J, Liu J, Pei D. Cao S, et al. Among authors: pei d. Cell Stem Cell. 2018 Apr 5;22(4):529-542.e5. doi: 10.1016/j.stem.2018.03.005. Cell Stem Cell. 2018. PMID: 29625068 Free article.
Short-Term Mitochondrial Permeability Transition Pore Opening Modulates Histone Lysine Methylation at the Early Phase of Somatic Cell Reprogramming.
Ying Z, Xiang G, Zheng L, Tang H, Duan L, Lin X, Zhao Q, Chen K, Wu Y, Xing G, Lv Y, Li L, Yang L, Bao F, Long Q, Zhou Y, He X, Wang Y, Gao M, Pei D, Chan WY, Liu X. Ying Z, et al. Among authors: pei d. Cell Metab. 2018 Dec 4;28(6):935-945.e5. doi: 10.1016/j.cmet.2018.08.001. Epub 2018 Aug 30. Cell Metab. 2018. PMID: 30174306 Free article.
1,561 results