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Page 1
Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways.
Khurana V, Peng J, Chung CY, Auluck PK, Fanning S, Tardiff DF, Bartels T, Koeva M, Eichhorn SW, Benyamini H, Lou Y, Nutter-Upham A, Baru V, Freyzon Y, Tuncbag N, Costanzo M, San Luis BJ, Schöndorf DC, Barrasa MI, Ehsani S, Sanjana N, Zhong Q, Gasser T, Bartel DP, Vidal M, Deleidi M, Boone C, Fraenkel E, Berger B, Lindquist S. Khurana V, et al. Among authors: benyamini h. Cell Syst. 2017 Feb 22;4(2):157-170.e14. doi: 10.1016/j.cels.2016.12.011. Epub 2017 Jan 25. Cell Syst. 2017. PMID: 28131822 Free PMC article.
Prediction of multimolecular assemblies by multiple docking.
Inbar Y, Benyamini H, Nussinov R, Wolfson HJ. Inbar Y, et al. Among authors: benyamini h. J Mol Biol. 2005 Jun 3;349(2):435-47. doi: 10.1016/j.jmb.2005.03.039. Epub 2005 Apr 13. J Mol Biol. 2005. PMID: 15890207
Single-cell transcriptomics reveals a senescence-associated IL-6/CCR6 axis driving radiodermatitis.
Paldor M, Levkovitch-Siany O, Eidelshtein D, Adar R, Enk CD, Marmary Y, Elgavish S, Nevo Y, Benyamini H, Plaschkes I, Klein S, Mali A, Rose-John S, Peled A, Galun E, Axelrod JH. Paldor M, et al. Among authors: benyamini h. EMBO Mol Med. 2022 Aug 8;14(8):e15653. doi: 10.15252/emmm.202115653. Epub 2022 Jul 4. EMBO Mol Med. 2022. PMID: 35785521 Free PMC article.
P450 oxidoreductase regulates barrier maturation by mediating retinoic acid metabolism in a model of the human BBB.
Zlotnik D, Rabinski T, Halfon A, Anzi S, Plaschkes I, Benyamini H, Nevo Y, Gershoni OY, Rosental B, Hershkovitz E, Ben-Zvi A, Vatine GD. Zlotnik D, et al. Among authors: benyamini h. Stem Cell Reports. 2022 Sep 13;17(9):2050-2063. doi: 10.1016/j.stemcr.2022.07.010. Epub 2022 Aug 11. Stem Cell Reports. 2022. PMID: 35961311 Free PMC article.
Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles Modulate Apoptosis, TNF Alpha and Interferon Gamma Response Gene mRNA Expression in T Lymphocytes.
Fracchia A, Khare D, Da'na S, Or R, Buxboim A, Nachmias B, Barkatz C, Golan-Gerstl R, Tiwari S, Stepensky P, Nevo Y, Benyamini H, Elgavish S, Almogi-Hazan O, Avni B. Fracchia A, et al. Among authors: benyamini h. Int J Mol Sci. 2023 Sep 5;24(18):13689. doi: 10.3390/ijms241813689. Int J Mol Sci. 2023. PMID: 37761990 Free PMC article.
Triangular correlation (TrC) between cancer aggressiveness, cell uptake capability, and cell deformability.
Brill-Karniely Y, Dror D, Duanis-Assaf T, Goldstein Y, Schwob O, Millo T, Orehov N, Stern T, Jaber M, Loyfer N, Vosk-Artzi M, Benyamini H, Bielenberg D, Kaplan T, Buganim Y, Reches M, Benny O. Brill-Karniely Y, et al. Among authors: benyamini h. Sci Adv. 2020 Jan 15;6(3):eaax2861. doi: 10.1126/sciadv.aax2861. eCollection 2020 Jan. Sci Adv. 2020. PMID: 31998832 Free PMC article.
Senolytic elimination of Cox2-expressing senescent cells inhibits the growth of premalignant pancreatic lesions.
Kolodkin-Gal D, Roitman L, Ovadya Y, Azazmeh N, Assouline B, Schlesinger Y, Kalifa R, Horwitz S, Khalatnik Y, Hochner-Ger A, Imam A, Demma JA, Winter E, Benyamini H, Elgavish S, Khatib AA, Meir K, Atlan K, Pikarsky E, Parnas O, Dor Y, Zamir G, Ben-Porath I, Krizhanovsky V. Kolodkin-Gal D, et al. Among authors: benyamini h. Gut. 2022 Feb;71(2):345-355. doi: 10.1136/gutjnl-2020-321112. Epub 2021 Mar 1. Gut. 2022. PMID: 33649045 Free PMC article.
Combined hepatocellular-cholangiocarcinoma derives from liver progenitor cells and depends on senescence and IL-6 trans-signaling.
Rosenberg N, Van Haele M, Lanton T, Brashi N, Bromberg Z, Adler H, Giladi H, Peled A, Goldenberg DS, Axelrod JH, Simerzin A, Chai C, Paldor M, Markezana A, Yaish D, Shemulian Z, Gross D, Barnoy S, Gefen M, Amran O, Claerhout S, Fernández-Vaquero M, García-Beccaria M, Heide D, Shoshkes-Carmel M, Schmidt Arras D, Elgavish S, Nevo Y, Benyamini H, Tirnitz-Parker JEE, Sanchez A, Herrera B, Safadi R, Kaestner KH, Rose-John S, Roskams T, Heikenwalder M, Galun E. Rosenberg N, et al. Among authors: benyamini h. J Hepatol. 2022 Dec;77(6):1631-1641. doi: 10.1016/j.jhep.2022.07.029. Epub 2022 Aug 18. J Hepatol. 2022. PMID: 35988690
The structure and interactions of the proline-rich domain of ASPP2.
Rotem S, Katz C, Benyamini H, Lebendiker M, Veprintsev D, Rüdiger S, Danieli T, Friedler A. Rotem S, et al. Among authors: benyamini h. J Biol Chem. 2008 Jul 4;283(27):18990-9. doi: 10.1074/jbc.M708717200. Epub 2008 Apr 30. J Biol Chem. 2008. PMID: 18448430 Free article.
Molecular basis of the interaction between the antiapoptotic Bcl-2 family proteins and the proapoptotic protein ASPP2.
Katz C, Benyamini H, Rotem S, Lebendiker M, Danieli T, Iosub A, Refaely H, Dines M, Bronner V, Bravman T, Shalev DE, Rüdiger S, Friedler A. Katz C, et al. Among authors: benyamini h. Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12277-82. doi: 10.1073/pnas.0711269105. Epub 2008 Aug 21. Proc Natl Acad Sci U S A. 2008. PMID: 18719108 Free PMC article.
Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies.
Nazeen S, Wang X, Zielinski D, Lam I, Hallacli E, Xu P, Ethier E, Strom R, Zanella CA, Nithianandam V, Ritter D, Henderson A, Saurat N, Afroz J, Nutter-Upham A, Benyamini H, Copty J, Ravishankar S, Morrow A, Mitchel J, Neavin D, Gupta R, Farbehi N, Grundman J, Myers RH, Scherzer CR, Trojanowski JQ, Van Deerlin VM, Cooper AA, Lee EB, Erlich Y, Lindquist S, Peng J, Geschwind DH, Powell J, Studer L, Feany MB, Sunyaev SR, Khurana V. Nazeen S, et al. Among authors: benyamini h. bioRxiv [Preprint]. 2024 Mar 7:2024.03.03.583145. doi: 10.1101/2024.03.03.583145. bioRxiv. 2024. PMID: 38496508 Free PMC article. Preprint.
AN1284 attenuates steatosis, lipogenesis, and fibrosis in mice with pre-existing non-alcoholic steatohepatitis and directly affects aryl hydrocarbon receptor in a hepatic cell line.
Yehezkel AS, Abudi N, Nevo Y, Benyamini H, Elgavish S, Weinstock M, Abramovitch R. Yehezkel AS, et al. Among authors: benyamini h. Front Endocrinol (Lausanne). 2023 Aug 16;14:1226808. doi: 10.3389/fendo.2023.1226808. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37664863 Free PMC article.
Amyloidogenic light chains impair plasma cell survival.
Pick M, Lebel E, Elgavish S, Benyamini H, Nevo Y, Hertz R, Bar-Tana J, Rognoni P, Merlini G, Gatt ME. Pick M, et al. Among authors: benyamini h. Haematologica. 2023 Dec 1;108(12):3359-3371. doi: 10.3324/haematol.2022.282484. Haematologica. 2023. PMID: 37381778 Free PMC article.
Taking geometry to its edge: fast unbound rigid (and hinge-bent) docking.
Schneidman-Duhovny D, Inbar Y, Polak V, Shatsky M, Halperin I, Benyamini H, Barzilai A, Dror O, Haspel N, Nussinov R, Wolfson HJ. Schneidman-Duhovny D, et al. Among authors: benyamini h. Proteins. 2003 Jul 1;52(1):107-12. doi: 10.1002/prot.10397. Proteins. 2003. PMID: 12784375