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15,723 results

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The Pseudomonas aeruginosa protease LasB directly activates IL-1β.
Sun J, LaRock DL, Skowronski EA, Kimmey JM, Olson J, Jiang Z, O'Donoghue AJ, Nizet V, LaRock CN. Sun J, et al. Among authors: jiang z. EBioMedicine. 2020 Oct;60:102984. doi: 10.1016/j.ebiom.2020.102984. Epub 2020 Sep 23. EBioMedicine. 2020. PMID: 32979835 Free PMC article.
Targeting proteasomes in infectious organisms to combat disease.
Bibo-Verdugo B, Jiang Z, Caffrey CR, O'Donoghue AJ. Bibo-Verdugo B, et al. Among authors: jiang z. FEBS J. 2017 May;284(10):1503-1517. doi: 10.1111/febs.14029. Epub 2017 Feb 16. FEBS J. 2017. PMID: 28122162 Free article. Review.
SmSP2: A serine protease secreted by the blood fluke pathogen Schistosoma mansoni with anti-hemostatic properties.
Leontovyč A, Ulrychová L, O'Donoghue AJ, Vondrášek J, Marešová L, Hubálek M, Fajtová P, Chanová M, Jiang Z, Craik CS, Caffrey CR, Mareš M, Dvořák J, Horn M. Leontovyč A, et al. Among authors: jiang z. PLoS Negl Trop Dis. 2018 Apr 20;12(4):e0006446. doi: 10.1371/journal.pntd.0006446. eCollection 2018 Apr. PLoS Negl Trop Dis. 2018. PMID: 29677188 Free PMC article.
Quantitative Multiplex Substrate Profiling of Peptidases by Mass Spectrometry.
Lapek JD Jr, Jiang Z, Wozniak JM, Arutyunova E, Wang SC, Lemieux MJ, Gonzalez DJ, O'Donoghue AJ. Lapek JD Jr, et al. Among authors: jiang z. Mol Cell Proteomics. 2019 May;18(5):968-981. doi: 10.1074/mcp.TIR118.001099. Epub 2019 Jan 31. Mol Cell Proteomics. 2019. PMID: 30705125 Free PMC article.
The Proteasome as a Drug Target in the Metazoan Pathogen, Schistosoma mansoni.
Bibo-Verdugo B, Wang SC, Almaliti J, Ta AP, Jiang Z, Wong DA, Lietz CB, Suzuki BM, El-Sakkary N, Hook V, Salvesen GS, Gerwick WH, Caffrey CR, O'Donoghue AJ. Bibo-Verdugo B, et al. Among authors: jiang z. ACS Infect Dis. 2019 Oct 11;5(10):1802-1812. doi: 10.1021/acsinfecdis.9b00237. Epub 2019 Aug 12. ACS Infect Dis. 2019. PMID: 31355632 Free PMC article.
20S Proteasome as a Drug Target in Trichomonas vaginalis.
O'Donoghue AJ, Bibo-Verdugo B, Miyamoto Y, Wang SC, Yang JZ, Zuill DE, Matsuka S, Jiang Z, Almaliti J, Caffrey CR, Gerwick WH, Eckmann L. O'Donoghue AJ, et al. Among authors: jiang z. Antimicrob Agents Chemother. 2019 Oct 22;63(11):e00448-19. doi: 10.1128/AAC.00448-19. Print 2019 Nov. Antimicrob Agents Chemother. 2019. PMID: 31451503 Free PMC article.
Dysregulation of Exosome Cargo by Mutant Tau Expressed in Human-induced Pluripotent Stem Cell (iPSC) Neurons Revealed by Proteomics Analyses.
Podvin S, Jones A, Liu Q, Aulston B, Ransom L, Ames J, Shen G, Lietz CB, Jiang Z, O'Donoghue AJ, Winston C, Ikezu T, Rissman RA, Yuan S, Hook V. Podvin S, et al. Among authors: jiang z. Mol Cell Proteomics. 2020 Jun;19(6):1017-1034. doi: 10.1074/mcp.RA120.002079. Epub 2020 Apr 15. Mol Cell Proteomics. 2020. PMID: 32295833 Free PMC article.
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[No authors listed] [No authors listed] PMID: 33451707
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[No authors listed] [No authors listed] PMID: 33451794
Insights into the catalytic properties of the mitochondrial rhomboid protease PARL.
Lysyk L, Brassard R, Arutyunova E, Siebert V, Jiang Z, Takyi E, Morrison M, Young HS, Lemberg MK, O'Donoghue AJ, Lemieux MJ. Lysyk L, et al. Among authors: jiang z. J Biol Chem. 2021 Jan-Jun;296:100383. doi: 10.1016/j.jbc.2021.100383. Epub 2021 Feb 6. J Biol Chem. 2021. PMID: 33556373 Free PMC article.
Characterization of glutamate carboxypeptidase 2 orthologs in trematodes.
Jedlickova L, Peterkova K, Boateng EM, Ulrychova L, Vacek V, Kutil Z, Jiang Z, Novakova Z, Snajdr I, Kim J, O'Donoghue AJ, Barinka C, Dvorak J. Jedlickova L, et al. Among authors: jiang z. Parasit Vectors. 2022 Dec 20;15(1):480. doi: 10.1186/s13071-022-05556-5. Parasit Vectors. 2022. PMID: 36539882 Free PMC article.
Multiplex substrate profiling by mass spectrometry for proteases.
Rohweder PJ, Jiang Z, Hurysz BM, O'Donoghue AJ, Craik CS. Rohweder PJ, et al. Among authors: jiang z. Methods Enzymol. 2023;682:375-411. doi: 10.1016/bs.mie.2022.09.009. Epub 2022 Dec 21. Methods Enzymol. 2023. PMID: 36948708 Free PMC article.
Analysis of Mitochondrial Transfer RNA Mutations in Breast Cancer.
Ding HJ, Zhao YP, Jiang ZC, Zhou DT, Zhu R. Ding HJ, et al. Among authors: jiang zc. Balkan J Med Genet. 2023 May 2;25(2):15-22. doi: 10.2478/bjmg-2022-0020. eCollection 2023 May. Balkan J Med Genet. 2023. PMID: 37265965 Free PMC article.
Association of nonmalignant portal vein thrombosis and clinical outcomes in patients with cirrhosis and acute variceal bleeding: a multicenter observational study.
Lv Y, Bai W, Zhu X, Xue H, Zhao J, Zhuge Y, Sun J, Zhang C, Ding P, Jiang Z, Zhu X, Ren W, LiZhang YK, Zhang W, Li K, Wang Z, Luo B, Li X, Yuan J, Yang Z, Guo W, Xia D, Xie H, Yang C, Pan Y, Yin Z, Fan D, Han G. Lv Y, et al. Among authors: jiang z. Hepatol Int. 2023 May 31. doi: 10.1007/s12072-023-10493-1. Online ahead of print. Hepatol Int. 2023. PMID: 37258989
Safety and immunogenicity of a bivalent HPV16/18 vaccine in Chinese females.
Shi LW, Li J, Yu BW, Huang LR, Li K, Ji M, Zhou LY, Yuan L, Yang SY, Chen JJ, Wang L, Jiang ZW, Li RC, Li YP, Xia JL, Mo ZJ, Li CG. Shi LW, et al. Hum Vaccin Immunother. 2023 May 30:2209001. doi: 10.1080/21645515.2023.2209001. Online ahead of print. Hum Vaccin Immunother. 2023. PMID: 37249310
ATB0,+-targeted nanoparticles initiate autophagy suppression to overcome chemoresistance for enhanced colorectal cancer therapy.
Chen Z, Chen H, Huang L, Duan B, Dai S, Cai W, Sun M, Jiang Z, Lu R, Jiang Y, Jiang X, Zheng H, Yao Q, Kim K, Lin G, Xie C, Chu M, Chen R, Kou L. Chen Z, et al. Among authors: jiang x, jiang z, jiang y. Int J Pharm. 2023 May 25;641:123082. doi: 10.1016/j.ijpharm.2023.123082. Online ahead of print. Int J Pharm. 2023. PMID: 37244464
MiR-3960 inhibits bladder cancer progression via targeting of DEXI.
Li W, Wang Z, Jiang Z, Yan Y, Yao X, Pan Z, Chen L, Wang F, Wang M, Qin Z. Li W, et al. Among authors: jiang z. Biochem Biophys Res Commun. 2023 May 18;668:8-18. doi: 10.1016/j.bbrc.2023.05.055. Online ahead of print. Biochem Biophys Res Commun. 2023. PMID: 37230046
Homeostatic control of an iron repressor in a GI tract resident.
Wang Y, Mao Y, Chen X, Huang X, Jiang Z, Yang K, Tian L, Jiang T, Zou Y, Ma X, Xu C, Zhou Z, Wu X, Pan L, Liang H, Zhong L, Chen C. Wang Y, et al. Among authors: jiang t, jiang z. Elife. 2023 May 25;12:e86075. doi: 10.7554/eLife.86075. Online ahead of print. Elife. 2023. PMID: 37227051 Free article.
Saxagliptin promotes random skin flap survival.
Meng Z, Wang K, Lan Q, Zhou T, Lin Y, Jiang Z, Chen J, Lin Y, Liu X, Lin H, Lin D. Meng Z, et al. Among authors: jiang z. Int Immunopharmacol. 2023 May 22;120:110364. doi: 10.1016/j.intimp.2023.110364. Online ahead of print. Int Immunopharmacol. 2023. PMID: 37224651
Spectroscopic signature of obstructed surface states in SrIn2P2.
Liu XR, Deng H, Liu Y, Yin Z, Chen C, Zhu YP, Yang Y, Jiang Z, Liu Z, Ye M, Shen D, Yin JX, Wang K, Liu Q, Zhao Y, Liu C. Liu XR, et al. Among authors: jiang z. Nat Commun. 2023 May 22;14(1):2905. doi: 10.1038/s41467-023-38589-0. Nat Commun. 2023. PMID: 37217499 Free PMC article.
A revamped rat reference genome improves the discovery of genetic diversity in laboratory rats.
de Jong TV, Pan Y, Rastas P, Munro D, Tutaj M, Akil H, Benner C, Chitre AS, Chow W, Colonna V, Dalgard CL, Demos WM, Doris PA, Garrison E, Geurts A, Gunturkun HM, Guryev V, Hourlier T, Howe K, Huang J, Kalbfleisch T, Kim P, Li L, Mahaffey S, Martin FJ, Mohammadi P, Ozel AB, Polesskaya O, Pravenec M, Prins P, Sebat J, Smith JR, Woods LCS, Tabakoff B, Tracey A, Uliano-Silva M, Villani F, Wang H, Sharp BM, Telese F, Jiang Z, Saba L, Wang X, Murphy TD, Palmer AA, Kwitek AE, Dwinell MMR, Williams RW, Li JZ, Chen H. de Jong TV, et al. Among authors: jiang z. bioRxiv. 2023 Apr 14:2023.04.13.536694. doi: 10.1101/2023.04.13.536694. Preprint. bioRxiv. 2023. PMID: 37214860 Free PMC article.
Lipid-anchored Proteasomes Control Membrane Protein Homeostasis.
Zhang R, Pan S, Zheng S, Liao Q, Jiang Z, Wang D, Li X, Hu A, Li X, Zhu Y, Shen X, Lei J, Zhong S, Zhang X, Huang L, Wang X, Huang L, Shen L, Song BL, Zhao J, Wang Z, Yang B, Guo X. Zhang R, et al. Among authors: jiang z. bioRxiv. 2023 May 12:2023.05.12.540509. doi: 10.1101/2023.05.12.540509. Preprint. bioRxiv. 2023. PMID: 37214852 Free PMC article.
Comparing Recombinant Human Rabies Monoclonal Antibody (Ormutivimab) with Human Rabies Immunoglobulin (HRIG) for Postexposure Prophylaxis: A Phase 3, Randomized, Double-Blind, Non-inferiority Trial.
Liu X, Li Y, Li J, Zhou J, Guo J, Pu Y, Jiang Y, Zhou Y, Jiang Z, Shu Q, Wang C, Wang J, Zhao Y, Zhao W, Wang H, Wei J, Yu H, Gao J, Li X. Liu X, et al. Among authors: jiang z, jiang y. Int J Infect Dis. 2023 May 19:S1201-9712(23)00569-6. doi: 10.1016/j.ijid.2023.05.017. Online ahead of print. Int J Infect Dis. 2023. PMID: 37211270 Free article.
Surface Electronic Structure Engineering of Manganese Bismuth Tellurides Guided by Micro-Focused Angle-Resolved Photoemission.
Volckaert K, Majchrzak P, Biswas D, Jones AJH, Bianchi M, Jiang Z, Dubourg R, Stenshøj RØ, Jensen ML, Jones NC, Hoffmann SV, Mi JL, Bremholm M, Pan XC, Chen YP, Hofmann P, Miwa JA, Ulstrup S. Volckaert K, et al. Among authors: jiang z. Adv Mater. 2023 May 19:e2301907. doi: 10.1002/adma.202301907. Online ahead of print. Adv Mater. 2023. PMID: 37204117
Insight into the roles of soluble, loosely bound and tightly bound extracellular polymeric substances produced by Enterobacter sp. in the Cd2+ and Pb2+ biosorption process: Characterization and mechanism.
Shi X, Ling Q, Jiang Z, Pei F, Xin M, Tan W, Chen X, Liu K, Ma J, Yu F, Li Y. Shi X, et al. Among authors: jiang z. Colloids Surf B Biointerfaces. 2023 May 13;227:113348. doi: 10.1016/j.colsurfb.2023.113348. Online ahead of print. Colloids Surf B Biointerfaces. 2023. PMID: 37201449
Designing strong, fast, high-performance hydrogel actuators.
Bin Asghar Abbasi B, Gigliotti M, Aloko S, Jolfaei MA, Spinks GM, Jiang Z. Bin Asghar Abbasi B, et al. Among authors: jiang z. Chem Commun (Camb). 2023 May 17. doi: 10.1039/d3cc01545a. Online ahead of print. Chem Commun (Camb). 2023. PMID: 37194593 Review.
Changes in microstates of first-episode untreated nonsuicidal self-injury adolescents exposed to negative emotional stimuli and after receiving rTMS intervention.
Zhao L, Zhou D, Hu J, He X, Peng X, Ma L, Liu X, Tao W, Chen R, Jiang Z, Zhang C, Liao J, Xiang J, Zeng Q, Dai L, Zhang Q, Hong S, Wang W, Kuang L. Zhao L, et al. Among authors: jiang z. Front Psychiatry. 2023 Apr 27;14:1151114. doi: 10.3389/fpsyt.2023.1151114. eCollection 2023. Front Psychiatry. 2023. PMID: 37181884 Free PMC article.
Pan-Asian adapted ESMO Clinical Practice Guidelines for the diagnosis, staging and treatment of patients with metastatic breast cancer.
Im SA, Gennari A, Park YH, Kim JH, Jiang ZF, Gupta S, Fadjari TH, Tamura K, Mastura MY, Abesamis-Tiambeng MLT, Lim EH, Lin CH, Sookprasert A, Parinyanitikul N, Tseng LM, Lee SC, Caguioa P, Singh M, Naito Y, Hukom RA, Smruti BK, Wang SS, Kim SB, Lee KH, Ahn HK, Peters S, Kim TW, Yoshino T, Pentheroudakis G, Curigliano G, Harbeck N. Im SA, et al. Among authors: jiang zf. ESMO Open. 2023 May 11;8(3):101541. doi: 10.1016/j.esmoop.2023.101541. Online ahead of print. ESMO Open. 2023. PMID: 37178669 Free PMC article.
Development of stem cell therapy for atherosclerosis.
Ma Y, Gu T, He S, He S, Jiang Z. Ma Y, et al. Among authors: jiang z. Mol Cell Biochem. 2023 May 13. doi: 10.1007/s11010-023-04762-8. Online ahead of print. Mol Cell Biochem. 2023. PMID: 37178375 Review.
Lateral septum as a melanocortin downstream site in obesity development.
Xu Y, Jiang Z, Li H, Cai J, Jiang Y, Otiz-Guzman J, Xu Y, Arenkiel BR, Tong Q. Xu Y, et al. Among authors: jiang z, jiang y. Cell Rep. 2023 May 30;42(5):112502. doi: 10.1016/j.celrep.2023.112502. Epub 2023 May 11. Cell Rep. 2023. PMID: 37171957 Free article.
GSDME-dependent pyroptosis signaling pathway in diabetic nephropathy.
Li S, Feng L, Li G, Liu R, Ma C, Wang L, Gao A, Liu C, Cui Y, Jiang Z, Xie Y, Wu Q, Wang X, Yang L, Qi Z, Shen Y. Li S, et al. Among authors: jiang z. Cell Death Discov. 2023 May 11;9(1):156. doi: 10.1038/s41420-023-01452-8. Cell Death Discov. 2023. PMID: 37169767 Free PMC article.
Risk factors of amyotrophic lateral sclerosis: a global meta-summary.
Duan QQ, Jiang Z, Su WM, Gu XJ, Wang H, Cheng YF, Cao B, Gao X, Wang Y, Chen YP. Duan QQ, et al. Among authors: jiang z. Front Neurosci. 2023 Apr 24;17:1177431. doi: 10.3389/fnins.2023.1177431. eCollection 2023. Front Neurosci. 2023. PMID: 37168926 Free PMC article.
A phase 3, multicenter, double-blind, randomized, placebo-controlled clinical trial to verify the efficacy and safety of ansofaxine (LY03005) for major depressive disorder.
Mi W, Di X, Wang Y, Li H, Xu X, Li L, Wang H, Wang G, Zhang K, Tian F, Luo J, Yang C, Zhou Y, Xie S, Zhong H, Wu B, Yang D, Chen Z, Li Y, Chen J, Lv S, Yi Q, Jiang Z, Tian J, Zhang H. Mi W, et al. Among authors: jiang z. Transl Psychiatry. 2023 May 10;13(1):163. doi: 10.1038/s41398-023-02435-0. Transl Psychiatry. 2023. PMID: 37164957 Free PMC article. Clinical Trial.
Discovery of a highly potent pan-RAF inhibitor IHMT-RAF-128 for cancer treatment.
Wang A, Liu J, Li X, Zou F, Qi Z, Qi S, Liu Q, Wang Z, Cao J, Jiang Z, Wang B, Ge J, Wang L, Wang W, Liu J, Liu Q. Wang A, et al. Among authors: jiang z. Eur J Pharmacol. 2023 May 8;952:175752. doi: 10.1016/j.ejphar.2023.175752. Online ahead of print. Eur J Pharmacol. 2023. PMID: 37164118
Single-cell transcriptome analysis of xenotransplanted human retinal organoids defines two migratory cell populations of nonretinal origin.
Liu YV, Santiago CP, Sogunro A, Konar GJ, Hu MW, McNally MM, Lu YC, Flores-Bellver M, Aparicio-Domingo S, Li KV, Li ZL, Agakishiev D, Hadyniak SE, Hussey KA, Creamer TJ, Orzolek LD, Teng D, Canto-Soler MV, Qian J, Jiang Z, Johnston RJ Jr, Blackshaw S, Singh MS. Liu YV, et al. Among authors: jiang z. Stem Cell Reports. 2023 May 9;18(5):1138-1154. doi: 10.1016/j.stemcr.2023.04.004. Stem Cell Reports. 2023. PMID: 37163980 Free PMC article.
Transmission of Alzheimer's Disease-Associated Microbiota Dysbiosis and its Impact on Cognitive Function: Evidence from Mouse Models and Human Patients.
Zhang Y, Shen Y, Liufu N, Liu L, Li W, Shi Z, Zheng H, Mei X, Chen CY, Jiang Z, Abtahi S, Dong Y, Liang F, Shi Y, Cheng L, Yang G, Kang JX, Wilkinson J, Xie Z. Zhang Y, et al. Among authors: jiang z. Res Sq. 2023 Apr 28:rs.3.rs-2790988. doi: 10.21203/rs.3.rs-2790988/v1. Preprint. Res Sq. 2023. PMID: 37162940 Free PMC article.
Identification of potential resistance mechanisms and therapeutic targets for the relapse of BCMA CAR-T therapy in relapsed/refractory multiple myeloma through single-cell sequencing.
Li W, Zhang B, Cao W, Zhang W, Li T, Liu L, Xu L, Gao F, Wang Y, Wang F, Xing H, Jiang Z, Shi J, Bian Z, Song Y. Li W, et al. Among authors: jiang z. Exp Hematol Oncol. 2023 May 8;12(1):44. doi: 10.1186/s40164-023-00402-5. Exp Hematol Oncol. 2023. PMID: 37158921 Free PMC article.
Combinational study with network pharmacology, molecular docking and preliminary experiments on exploring common mechanisms underlying the effects of weijing decoction on various pulmonary diseases.
Li JX, Han ZX, Cheng X, Zhang FL, Zhang JY, Su ZJ, Li BP, Jiang ZR, Li RZ, Xie Y, Yan PY, Tang L, Yang JS. Li JX, et al. Heliyon. 2023 Apr 20;9(5):e15631. doi: 10.1016/j.heliyon.2023.e15631. eCollection 2023 May. Heliyon. 2023. PMID: 37153415 Free PMC article.
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