Tan NS - Search Results

1

Angptl4 integrates dietary and microbial signals to disrupt gut barrier function in MASH.

Chua D, Low ZS, Kim JHS, Lee YH, Kiatbumrung R, Somnark P, Xu M, Shi Y, Kaushal G, Vos MIG, Mahadevan A, Hooi N, Raj M, Sviriaeva E, Cui B, Tan S, Kasahara K, Ho CL, Wahli W, Yew KC, Wong SH, Cheung C, Pal M, Zhang R, Chuaypen N, Tangkijvanich P, Cheng HS, Li L, Tan NS. Chua D, et al. Among authors: tan ns. Nat Commun. 2026 May 22. doi: 10.1038/s41467-026-72575-6. Online ahead of print. Nat Commun. 2026. PMID: 42173835 Free article.

2

Single-bacterial cell insights into mechanisms of ceftriaxone resistance in Neisseria subflava.

Zhang X, Cheng HS, Zhan X, Li X, Huang J, Liu H, Chua D, Wang G, Li X, Shi Y, Wang F, Xu Z, Qu J, Pethe K, Li G, Tan NS, Mac Aogáin M, Chotirmall SH, Li L. Zhang X, et al. Among authors: tan ns. Nat Commun. 2026 Mar 27;17(1):4532. doi: 10.1038/s41467-026-68621-y. Nat Commun. 2026. PMID: 41896210 Free PMC article.

3

Exploiting vulnerabilities of cancer by targeting nuclear receptors of stromal cells in tumor microenvironment.

Cheng HS, Lee JXT, Wahli W, Tan NS. Cheng HS, et al. Among authors: tan ns. Mol Cancer. 2019 Mar 30;18(1):51. doi: 10.1186/s12943-019-0971-9. Mol Cancer. 2019. PMID: 30925918 Free PMC article. Review.

4

Deficiency in fibroblast PPARβ/δ reduces nonmelanoma skin cancers in mice.

Tan MWY, Sng MK, Cheng HS, Low ZS, Leong BJJ, Chua D, Tan EHP, Chan JSK, Yip YS, Lee YH, Pal M, Wang X, Wahli W, Tan NS. Tan MWY, et al. Among authors: tan ehp, tan ns. Cell Death Differ. 2020 Sep;27(9):2668-2680. doi: 10.1038/s41418-020-0535-y. Epub 2020 Apr 20. Cell Death Differ. 2020. PMID: 32313198 Free PMC article.

5

PPARs and Tumor Microenvironment: The Emerging Roles of the Metabolic Master Regulators in Tumor Stromal-Epithelial Crosstalk and Carcinogenesis.

Cheng HS, Yip YS, Lim EKY, Wahli W, Tan NS. Cheng HS, et al. Among authors: tan ns. Cancers (Basel). 2021 Apr 29;13(9):2153. doi: 10.3390/cancers13092153. Cancers (Basel). 2021. PMID: 33946986 Free PMC article. Review.

6

Single-cell analysis of skin immune cells reveals an Angptl4-ifi20b axis that regulates monocyte differentiation during wound healing.

Wee WKJ, Low ZS, Ooi CK, Henategala BP, Lim ZGR, Yip YS, Vos MIG, Tan WWR, Cheng HS, Tan NS. Wee WKJ, et al. Among authors: tan wwr, tan ns. Cell Death Dis. 2022 Feb 24;13(2):180. doi: 10.1038/s41419-022-04638-7. Cell Death Dis. 2022. PMID: 35210411 Free PMC article.

7

Utility of Human Relevant Preclinical Animal Models in Navigating NAFLD to MAFLD Paradigm.

Chua D, Low ZS, Cheam GX, Ng AS, Tan NS. Chua D, et al. Among authors: tan ns. Int J Mol Sci. 2022 Nov 25;23(23):14762. doi: 10.3390/ijms232314762. Int J Mol Sci. 2022. PMID: 36499091 Free PMC article. Review.

8

YWHAG Deficiency Disrupts the EMT-Associated Network to Induce Oxidative Cell Death and Prevent Metastasis.

Lee JXT, Tan WR, Low ZS, Lee JQ, Chua D, Yeo WDC, See B, Vos MIG, Yasuda T, Nomura S, Cheng HS, Tan NS. Lee JXT, et al. Among authors: tan wr, tan ns. Adv Sci (Weinh). 2023 Nov;10(31):e2301714. doi: 10.1002/advs.202301714. Epub 2023 Sep 27. Adv Sci (Weinh). 2023. PMID: 37759388 Free PMC article.

9

The LIDPAD Mouse Model Captures the Multisystem Interactions and Extrahepatic Complications in MASLD.

Low ZS, Chua D, Cheng HS, Tee R, Tan WR, Ball C, Sahib NBE, Ng SS, Qu J, Liu Y, Hong H, Cai C, Rao NCL, Wee A, Muthiah MD, Bichler Z, Mickelson B, Kong MS, Tay VS, Yan Z, Chen J, Ng AS, Yip YS, Vos MIG, Tan NA, Lim DL, Lim DXE, Chittezhath M, Yaligar J, Verma SK, Poptani H, Guan XL, Velan SS, Ali Y, Li L, Tan NS, Wahli W. Low ZS, et al. Among authors: tan wr, tan na, tan ns. Adv Sci (Weinh). 2024 Sep;11(35):e2404326. doi: 10.1002/advs.202404326. Epub 2024 Jul 1. Adv Sci (Weinh). 2024. PMID: 38952069 Free PMC article.

10

Author Correction: Hydrogel dressings with intrinsic antibiofilm and antioxidative dual functionalities accelerate infected diabetic wound healing.

Pranantyo D, Yeo CK, Wu Y, Fan C, Xu X, Yip YS, Vos MIG, Mahadevegowda SH, Lim PLK, Yang L, Hammond PT, Leavesley DI, Tan NS, Chan-Park MB. Pranantyo D, et al. Among authors: tan ns. Nat Commun. 2025 Oct 10;16(1):9047. doi: 10.1038/s41467-025-64329-7. Nat Commun. 2025. PMID: 41073442 Free PMC article. No abstract available.

11

Insights into the Role of PPARβ/δ in NAFLD.

Chen J, Montagner A, Tan NS, Wahli W. Chen J, et al. Among authors: tan ns. Int J Mol Sci. 2018 Jun 27;19(7):1893. doi: 10.3390/ijms19071893. Int J Mol Sci. 2018. PMID: 29954129 Free PMC article. Review.

12

Exploration and Development of PPAR Modulators in Health and Disease: An Update of Clinical Evidence.

Cheng HS, Tan WR, Low ZS, Marvalim C, Lee JYH, Tan NS. Cheng HS, et al. Among authors: tan wr, tan ns. Int J Mol Sci. 2019 Oct 11;20(20):5055. doi: 10.3390/ijms20205055. Int J Mol Sci. 2019. PMID: 31614690 Free PMC article. Review.

13

Hydrogel dressings with intrinsic antibiofilm and antioxidative dual functionalities accelerate infected diabetic wound healing.

Pranantyo D, Yeo CK, Wu Y, Fan C, Xu X, Yip YS, Vos MIG, Mahadevegowda SH, Lim PLK, Yang L, Hammond PT, Leavesley DI, Tan NS, Chan-Park MB. Pranantyo D, et al. Among authors: tan ns. Nat Commun. 2024 Feb 1;15(1):954. doi: 10.1038/s41467-024-44968-y. Nat Commun. 2024. PMID: 38296937 Free PMC article.

14

Advancements and Challenges in Modeling Mechanobiology in Intestinal Host-Microbiota Interaction.

Cheng HS, Tey YH, Hu SY, Yeo AYN, Ngo ZH, Kim JHS, Tan NS. Cheng HS, et al. Among authors: tan ns. ACS Appl Mater Interfaces. 2025 Jun 4;17(22):31698-31713. doi: 10.1021/acsami.4c20961. Epub 2025 May 18. ACS Appl Mater Interfaces. 2025. PMID: 40382722 Free PMC article. Review.

15

Reactive oxygen species: a volatile driver of field cancerization and metastasis.

Liao Z, Chua D, Tan NS. Liao Z, et al. Among authors: tan ns. Mol Cancer. 2019 Mar 30;18(1):65. doi: 10.1186/s12943-019-0961-y. Mol Cancer. 2019. PMID: 30927919 Free PMC article. Review.

16

The Potential of the FSP1cre-Pparb/d^-^/^- Mouse Model for Studying Juvenile NAFLD.

Chen J, Zhuang Y, Sng MK, Tan NS, Wahli W. Chen J, et al. Among authors: tan ns. Int J Mol Sci. 2019 Oct 15;20(20):5115. doi: 10.3390/ijms20205115. Int J Mol Sci. 2019. PMID: 31618976 Free PMC article.

17

Endothelial-immune crosstalk contributes to vasculopathy in nonalcoholic fatty liver disease.

Ng CY, Lee KL, Muthiah MD, Wu KX, Chioh FWJ, Tan K, Soon GST, Shabbir A, Loo WM, Low ZS, Chen Q, Tan NS, Ng HH, Dan YY, Cheung C. Ng CY, et al. Among authors: tan k, tan ns. EMBO Rep. 2022 Jun 7;23(6):e54271. doi: 10.15252/embr.202154271. Epub 2022 Apr 11. EMBO Rep. 2022. PMID: 35403791 Free PMC article.

18

Lessons on Drug Development: A Literature Review of Challenges Faced in Nonalcoholic Fatty Liver Disease (NAFLD) Clinical Trials.

Chen JYS, Chua D, Lim CO, Ho WX, Tan NS. Chen JYS, et al. Among authors: tan ns. Int J Mol Sci. 2022 Dec 21;24(1):158. doi: 10.3390/ijms24010158. Int J Mol Sci. 2022. PMID: 36613602 Free PMC article. Review.

19

The Blood Microbiome and Health: Current Evidence, Controversies, and Challenges.

Cheng HS, Tan SP, Wong DMK, Koo WLY, Wong SH, Tan NS. Cheng HS, et al. Among authors: tan sp, tan ns. Int J Mol Sci. 2023 Mar 15;24(6):5633. doi: 10.3390/ijms24065633. Int J Mol Sci. 2023. PMID: 36982702 Free PMC article. Review.

20

Attenuating Epithelial-to-Mesenchymal Transition in Cancer through Angiopoietin-Like 4 Inhibition in a 3D Tumor Microenvironment Model.

Liao Z, Lim JJH, Lee JXT, Chua D, Vos MIG, Yip YS, Too CB, Cao H, Wang JK, Shou Y, Tay A, Lehti K, Cheng HS, Tay CY, Tan NS. Liao Z, et al. Among authors: tan ns. Adv Healthc Mater. 2024 Apr;13(10):e2303481. doi: 10.1002/adhm.202303481. Epub 2023 Nov 29. Adv Healthc Mater. 2024. PMID: 37987244

21

A 3D physio-mimetic interpenetrating network-based platform to decode the pro and anti-tumorigenic properties of cancer-associated fibroblasts.

Cao H, Cheng HS, Wang JK, Tan NS, Tay CY. Cao H, et al. Among authors: tan ns. Acta Biomater. 2021 Sep 15;132:448-460. doi: 10.1016/j.actbio.2021.03.037. Epub 2021 Mar 22. Acta Biomater. 2021. PMID: 33766799

22

Depletion of Gram-Positive Bacteria Impacts Hepatic Biological Functions During the Light Phase.

Oh HYP, Ellero-Simatos S, Manickam R, Tan NS, Guillou H, Wahli W. Oh HYP, et al. Among authors: tan ns. Int J Mol Sci. 2019 Feb 14;20(4):812. doi: 10.3390/ijms20040812. Int J Mol Sci. 2019. PMID: 30769793 Free PMC article.

23

PPARβ/δ Agonism Upregulates Forkhead Box A2 to Reduce Inflammation in C2C12 Myoblasts and in Skeletal Muscle.

Phua WWT, Tan WR, Yip YS, Hew ID, Wee JWK, Cheng HS, Leow MKS, Wahli W, Tan NS. Phua WWT, et al. Among authors: tan wr, tan ns. Int J Mol Sci. 2020 Mar 4;21(5):1747. doi: 10.3390/ijms21051747. Int J Mol Sci. 2020. PMID: 32143325 Free PMC article.

24

Angiopoietin-like 4 regulates epidermal differentiation.

Pal M, Tan MJ, Huang RL, Goh YY, Wang XL, Tang MB, Tan NS. Pal M, et al. Among authors: tan mj, tan ns. PLoS One. 2011;6(9):e25377. doi: 10.1371/journal.pone.0025377. Epub 2011 Sep 22. PLoS One. 2011. PMID: 21966511 Free PMC article.

25

The establishment of COPD organoids to study host-pathogen interaction reveals enhanced viral fitness of SARS-CoV-2 in bronchi.

Chan LLY, Anderson DE, Cheng HS, Ivan FX, Chen S, Kang AEZ, Foo R, Gamage AM, Tiew PY, Koh MS, Lee KCH, Nichol K, Pathinayake PS, Chan YL, Yeo TW, Oliver BG, Wark PAB, Liu L, Tan NS, Wang LF, Chotirmall SH. Chan LLY, et al. Among authors: tan ns. Nat Commun. 2022 Dec 10;13(1):7635. doi: 10.1038/s41467-022-35253-x. Nat Commun. 2022. PMID: 36496442 Free PMC article.

26

Peroxisome proliferator-activated receptor-beta as a target for wound healing drugs.

Tan NS, Michalik L, Desvergne B, Wahli W. Tan NS, et al. Expert Opin Ther Targets. 2004 Feb;8(1):39-48. doi: 10.1517/14728222.8.1.39. Expert Opin Ther Targets. 2004. PMID: 14996617 Review.

27

Genetic- or transforming growth factor-beta 1-induced changes in epidermal peroxisome proliferator-activated receptor beta/delta expression dictate wound repair kinetics.

Tan NS, Michalik L, Desvergne B, Wahli W. Tan NS, et al. J Biol Chem. 2005 May 6;280(18):18163-70. doi: 10.1074/jbc.M412829200. Epub 2005 Feb 11. J Biol Chem. 2005. PMID: 15708854 Free article.

28

Targeting vascular leakage in lung inflammation.

Li L, Chow VT, Tan NS. Li L, et al. Among authors: tan ns. Oncotarget. 2015 Aug 14;6(23):19338-9. doi: 10.18632/oncotarget.4907. Oncotarget. 2015. PMID: 26305720 Free PMC article. No abstract available.

29

Peroxisome proliferator-activated receptor (PPAR)-beta as a target for wound healing drugs: what is possible?

Tan NS, Michalik L, Desvergne B, Wahli W. Tan NS, et al. Am J Clin Dermatol. 2003;4(8):523-30. doi: 10.2165/00128071-200304080-00001. Am J Clin Dermatol. 2003. PMID: 12862494 Review.

30

Scar prevention through topical delivery of gelatin-tyramine-siSPARC nanoplex loaded in dissolvable hyaluronic acid microneedle patch across skin barrier.

Chun YY, Tan WWR, Vos MIG, Chan WK, Tey HL, Tan NS, Tan TTY. Chun YY, et al. Among authors: tan wwr, tan tty, tan ns. Biomater Sci. 2022 Jul 12;10(14):3963-3971. doi: 10.1039/d2bm00572g. Biomater Sci. 2022. PMID: 35708018

31

Smad3 deficiency in mice protects against insulin resistance and obesity induced by a high-fat diet.

Tan CK, Leuenberger N, Tan MJ, Yan YW, Chen Y, Kambadur R, Wahli W, Tan NS. Tan CK, et al. Among authors: tan mj, tan ns. Diabetes. 2011 Feb;60(2):464-76. doi: 10.2337/db10-0801. Diabetes. 2011. PMID: 21270259 Free PMC article.

32

Epithelial-mesenchymal transition of cancer cells using bioengineered hybrid scaffold composed of hydrogel/3D-fibrous framework.

Pal M, Chen H, Lee BH, Lee JYH, Yip YS, Tan NS, Tan LP. Pal M, et al. Among authors: tan lp, tan ns. Sci Rep. 2019 Jun 20;9(1):8997. doi: 10.1038/s41598-019-45384-9. Sci Rep. 2019. PMID: 31222037 Free PMC article.

33

Roles of Estrogens in the Healthy and Diseased Oviparous Vertebrate Liver.

Tramunt B, Montagner A, Tan NS, Gourdy P, Rémignon H, Wahli W. Tramunt B, et al. Among authors: tan ns. Metabolites. 2021 Jul 30;11(8):502. doi: 10.3390/metabo11080502. Metabolites. 2021. PMID: 34436443 Free PMC article. Review.

34

Squid Suckerin-Spider Silk Fusion Protein Hydrogel for Delivery of Mesenchymal Stem Cell Secretome to Chronic Wounds.

Koh K, Wang JK, Chen JXY, Hiew SH, Cheng HS, Gabryelczyk B, Vos MIG, Yip YS, Chen L, Sobota RM, Chua DKK, Tan NS, Tay CY, Miserez A. Koh K, et al. Among authors: tan ns. Adv Healthc Mater. 2023 Jan;12(1):e2201900. doi: 10.1002/adhm.202201900. Epub 2022 Oct 17. Adv Healthc Mater. 2023. PMID: 36177679

35

Controlled-release nanoencapsulating microcapsules to combat inflammatory diseases.

Baek JS, Yeo EW, Lee YH, Tan NS, Loo SCJ. Baek JS, et al. Among authors: tan ns. Drug Des Devel Ther. 2017 Jun 8;11:1707-1717. doi: 10.2147/DDDT.S133344. eCollection 2017. Drug Des Devel Ther. 2017. PMID: 28652708 Free PMC article.

36

Multiple expression control mechanisms of peroxisome proliferator-activated receptors and their target genes.

Tan NS, Michalik L, Desvergne B, Wahli W. Tan NS, et al. J Steroid Biochem Mol Biol. 2005 Feb;93(2-5):99-105. doi: 10.1016/j.jsbmb.2004.12.025. J Steroid Biochem Mol Biol. 2005. PMID: 15860251 Review.

37

Targeting metabolic flexibility via angiopoietin-like 4 protein sensitizes metastatic cancer cells to chemotherapy drugs.

Lim MMK, Wee JWK, Soong JC, Chua D, Tan WR, Lizwan M, Li Y, Teo Z, Goh WWB, Zhu P, Tan NS. Lim MMK, et al. Among authors: tan wr, tan ns. Mol Cancer. 2018 Oct 20;17(1):152. doi: 10.1186/s12943-018-0904-z. Mol Cancer. 2018. PMID: 30342537 Free PMC article.

38

ROS release by PPARβ/δ-null fibroblasts reduces tumor load through epithelial antioxidant response.

Tan EHP, Sng MK, How ISB, Chan JSK, Chen J, Tan CK, Wahli W, Tan NS. Tan EHP, et al. Among authors: tan ck, tan ns. Oncogene. 2018 Apr;37(15):2067-2078. doi: 10.1038/s41388-017-0109-8. Epub 2018 Jan 25. Oncogene. 2018. PMID: 29367760 Free PMC article.

39

Transcriptional control of physiological and pathological processes by the nuclear receptor PPARβ/δ.

Tan NS, Vázquez-Carrera M, Montagner A, Sng MK, Guillou H, Wahli W. Tan NS, et al. Prog Lipid Res. 2016 Oct;64:98-122. doi: 10.1016/j.plipres.2016.09.001. Epub 2016 Sep 22. Prog Lipid Res. 2016. PMID: 27665713 Review. No abstract available.

40

TLR7 promotes smoke-induced experimental lung damage through the activity of mast cell tryptase.

Liu G, Haw TJ, Starkey MR, Philp AM, Pavlidis S, Nalkurthi C, Nair PM, Gomez HM, Hanish I, Hsu AC, Hortle E, Pickles S, Rojas-Quintero J, Estepar RSJ, Marshall JE, Kim RY, Collison AM, Mattes J, Idrees S, Faiz A, Hansbro NG, Fukui R, Murakami Y, Cheng HS, Tan NS, Chotirmall SH, Horvat JC, Foster PS, Oliver BG, Polverino F, Ieni A, Monaco F, Caramori G, Sohal SS, Bracke KR, Wark PA, Adcock IM, Miyake K, Sin DD, Hansbro PM. Liu G, et al. Among authors: tan ns. Nat Commun. 2023 Nov 14;14(1):7349. doi: 10.1038/s41467-023-42913-z. Nat Commun. 2023. PMID: 37963864 Free PMC article.

41

Essential role of Smad3 in the inhibition of inflammation-induced PPARbeta/delta expression.

Tan NS, Michalik L, Di-Poï N, Ng CY, Mermod N, Roberts AB, Desvergne B, Wahli W. Tan NS, et al. EMBO J. 2004 Oct 27;23(21):4211-21. doi: 10.1038/sj.emboj.7600437. Epub 2004 Oct 7. EMBO J. 2004. PMID: 15470497 Free PMC article.

42

Kinomic profile in patient-derived glioma cells during hypoxia reveals c-MET-PI3K dependency for adaptation.

Cheng HS, Marvalim C, Zhu P, Law CLD, Low ZYJ, Chong YK, Ang BT, Tang C, Tan NS. Cheng HS, et al. Among authors: tan ns. Theranostics. 2021 Mar 5;11(11):5127-5142. doi: 10.7150/thno.54741. eCollection 2021. Theranostics. 2021. PMID: 33859738 Free PMC article.

43

High Glucose Restraint of Acetylcholine-Induced Keratinocyte Epithelial-Mesenchymal Transition Is Mitigated by p38 Inhibition.

Tan MWY, Tan WR, Kong ZQ, Toh JH, Wee WKJ, Teo EML, Cheng HS, Wang X, Tan NS. Tan MWY, et al. Among authors: tan wr, tan ns. J Invest Dermatol. 2021 Jun;141(6):1438-1449.e9. doi: 10.1016/j.jid.2020.10.026. Epub 2020 Dec 15. J Invest Dermatol. 2021. PMID: 33333125 Free article.

44

Antiapoptotic role of PPARbeta in keratinocytes via transcriptional control of the Akt1 signaling pathway.

Di-Poï N, Tan NS, Michalik L, Wahli W, Desvergne B. Di-Poï N, et al. Among authors: tan ns. Mol Cell. 2002 Oct;10(4):721-33. doi: 10.1016/s1097-2765(02)00646-9. Mol Cell. 2002. PMID: 12419217 Free article.

45

Promoter rearrangements cause species-specific hepatic regulation of the glyoxylate reductase/hydroxypyruvate reductase gene by the peroxisome proliferator-activated receptor alpha.

Genolet R, Kersten S, Braissant O, Mandard S, Tan NS, Bucher P, Desvergne B, Michalik L, Wahli W. Genolet R, et al. Among authors: tan ns. J Biol Chem. 2005 Jun 24;280(25):24143-52. doi: 10.1074/jbc.M502649200. Epub 2005 Apr 19. J Biol Chem. 2005. PMID: 15840574 Free article.

46

The nuclear hormone receptor peroxisome proliferator-activated receptor beta/delta potentiates cell chemotactism, polarization, and migration.

Tan NS, Icre G, Montagner A, Bordier-ten-Heggeler B, Wahli W, Michalik L. Tan NS, et al. Mol Cell Biol. 2007 Oct;27(20):7161-75. doi: 10.1128/MCB.00436-07. Epub 2007 Aug 6. Mol Cell Biol. 2007. PMID: 17682064 Free PMC article.

47

Regulation of epithelial-mesenchymal IL-1 signaling by PPARbeta/delta is essential for skin homeostasis and wound healing.

Chong HC, Tan MJ, Philippe V, Tan SH, Tan CK, Ku CW, Goh YY, Wahli W, Michalik L, Tan NS. Chong HC, et al. Among authors: tan mj, tan ck, tan sh, tan ns. J Cell Biol. 2009 Mar 23;184(6):817-31. doi: 10.1083/jcb.200809028. J Cell Biol. 2009. PMID: 19307598 Free PMC article.

48

Micropatterned matrix directs differentiation of human mesenchymal stem cells towards myocardial lineage.

Tay CY, Yu H, Pal M, Leong WS, Tan NS, Ng KW, Leong DT, Tan LP. Tay CY, et al. Among authors: tan lp, tan ns. Exp Cell Res. 2010 Apr 15;316(7):1159-68. doi: 10.1016/j.yexcr.2010.02.010. Epub 2010 Feb 13. Exp Cell Res. 2010. PMID: 20156435

49

Angiopoietin-like 4 protein elevates the prosurvival intracellular O2(-):H2O2 ratio and confers anoikis resistance to tumors.

Zhu P, Tan MJ, Huang RL, Tan CK, Chong HC, Pal M, Lam CR, Boukamp P, Pan JY, Tan SH, Kersten S, Li HY, Ding JL, Tan NS. Zhu P, et al. Among authors: tan mj, tan ck, tan sh, tan ns. Cancer Cell. 2011 Mar 8;19(3):401-15. doi: 10.1016/j.ccr.2011.01.018. Cancer Cell. 2011. PMID: 21397862 Free article.

50

Impact of Mixture Effects between Emerging Organic Contaminants on Cytotoxicity: A Systems Biological Understanding of Synergism between Tris(1,3-dichloro-2-propyl)phosphate and Triphenyl Phosphate.

Zhang Y, Liu M, Peng B, Jia S, Koh D, Wang Y, Cheng HS, Tan NS, Warth B, Chen D, Fang M. Zhang Y, et al. Among authors: tan ns. Environ Sci Technol. 2020 Sep 1;54(17):10722-10734. doi: 10.1021/acs.est.0c02188. Epub 2020 Aug 18. Environ Sci Technol. 2020. PMID: 32786581

51

Dual p38MAPK and MEK inhibition disrupts adaptive chemoresistance in mesenchymal glioblastoma to temozolomide.

Cheng HS, Chong YK, Lim EKY, Lee XY, Pang QY, Novera W, Marvalim C, Lee JXT, Ang BT, Tang C, Tan NS. Cheng HS, et al. Among authors: tan ns. Neuro Oncol. 2024 Jul 5;26(7):1247-1261. doi: 10.1093/neuonc/noae028. Neuro Oncol. 2024. PMID: 38366847 Free PMC article.

52

Building a Foundation SERS Model for Lipids through Fatty Acid Pretraining for Annotation across Chemical Spaces.

Han R, Tan EX, Xie Y, Cheng HS, Tan NS, Lv Y, Phang IY, Ling XY. Han R, et al. Among authors: tan ns. ACS Appl Mater Interfaces. 2026 Mar 25;18(11):17168-17179. doi: 10.1021/acsami.6c00759. Epub 2026 Mar 12. ACS Appl Mater Interfaces. 2026. PMID: 41817099

53

Epithelium-mesenchyme interactions control the activity of peroxisome proliferator-activated receptor beta/delta during hair follicle development.

Di-Poï N, Ng CY, Tan NS, Yang Z, Hemmings BA, Desvergne B, Michalik L, Wahli W. Di-Poï N, et al. Among authors: tan ns. Mol Cell Biol. 2005 Mar;25(5):1696-712. doi: 10.1128/MCB.25.5.1696-1712.2005. Mol Cell Biol. 2005. PMID: 15713628 Free PMC article.

54

Investigating the Role of PPARβ/δ in Retinal Vascular Remodeling Using Pparβ/δ-Deficient Mice.

Ho SY, Kwan YP, Qiu B, Tan A, Murray HL, Barathi VA, Tan NS, Cheung CMG, Wong TY, Wahli W, Wang X. Ho SY, et al. Among authors: tan a, tan ns. Int J Mol Sci. 2020 Jun 20;21(12):4403. doi: 10.3390/ijms21124403. Int J Mol Sci. 2020. PMID: 32575793 Free PMC article.

55

Angiopoietin-like 4 interacts with integrins beta1 and beta5 to modulate keratinocyte migration.

Goh YY, Pal M, Chong HC, Zhu P, Tan MJ, Punugu L, Lam CR, Yau YH, Tan CK, Huang RL, Tan SM, Tang MB, Ding JL, Kersten S, Tan NS. Goh YY, et al. Among authors: tan sm, tan mj, tan ck, tan ns. Am J Pathol. 2010 Dec;177(6):2791-803. doi: 10.2353/ajpath.2010.100129. Epub 2010 Oct 15. Am J Pathol. 2010. PMID: 20952587 Free PMC article.

56

The anti-apoptotic role of PPARbeta contributes to efficient skin wound healing.

Di-Poï N, Michalik L, Tan NS, Desvergne B, Wahli W. Di-Poï N, et al. Among authors: tan ns. J Steroid Biochem Mol Biol. 2003 Jun;85(2-5):257-65. doi: 10.1016/s0960-0760(03)00215-2. J Steroid Biochem Mol Biol. 2003. PMID: 12943711

57

Angiopoietin-like 4 interacts with matrix proteins to modulate wound healing.

Goh YY, Pal M, Chong HC, Zhu P, Tan MJ, Punugu L, Tan CK, Huang RL, Sze SK, Tang MBY, Ding JL, Kersten S, Tan NS. Goh YY, et al. Among authors: tan mj, tan ck, tan ns. J Biol Chem. 2010 Oct 22;285(43):32999-33009. doi: 10.1074/jbc.M110.108175. Epub 2010 Aug 21. J Biol Chem. 2010. PMID: 20729546 Free PMC article.

58

TAK1 regulates SCF expression to modulate PKBα activity that protects keratinocytes from ROS-induced apoptosis.

Lam CR, Tan MJ, Tan SH, Tang MB, Cheung PC, Tan NS. Lam CR, et al. Among authors: tan mj, tan sh, tan ns. Cell Death Differ. 2011 Jul;18(7):1120-9. doi: 10.1038/cdd.2010.182. Epub 2011 Jan 14. Cell Death Differ. 2011. PMID: 21233843 Free PMC article.

59

Bio-inspired micropatterned platform to steer stem cell differentiation.

Tay CY, Pal M, Yu H, Leong WS, Tan NS, Ng KW, Venkatraman S, Boey F, Leong DT, Tan LP. Tay CY, et al. Among authors: tan lp, tan ns. Small. 2011 May 23;7(10):1416-21. doi: 10.1002/smll.201002298. Epub 2011 Apr 15. Small. 2011. PMID: 21495185 No abstract available.

60

Smad3 signaling is required for satellite cell function and myogenic differentiation of myoblasts.

Ge X, McFarlane C, Vajjala A, Lokireddy S, Ng ZH, Tan CK, Tan NS, Wahli W, Sharma M, Kambadur R. Ge X, et al. Among authors: tan ck, tan ns. Cell Res. 2011 Nov;21(11):1591-604. doi: 10.1038/cr.2011.72. Epub 2011 Apr 19. Cell Res. 2011. PMID: 21502976 Free PMC article.

61

Novel method to improve vascularization of tissue engineered constructs with biodegradable fibers.

Wong HK, Ivan Lam CR, Wen F, Mark Chong SK, Tan NS, Jerry C, Pal M, Tan LP. Wong HK, et al. Among authors: tan lp, tan ns. Biofabrication. 2016 Jan 7;8(1):015004. doi: 10.1088/1758-5090/8/1/015004. Biofabrication. 2016. PMID: 26741237

62

Selective deletion of PPARβ/δ in fibroblasts causes dermal fibrosis by attenuated LRG1 expression.

Sng MK, Chan JSK, Teo Z, Phua T, Tan EHP, Wee JWK, Koh NJN, Tan CK, Chen JP, Pal M, Tong BMK, Tnay YL, Ng XR, Zhu P, Chiba S, Wang X, Wahli W, Tan NS. Sng MK, et al. Among authors: tan ehp, tan ck, tan ns. Cell Discov. 2018 Apr 3;4:15. doi: 10.1038/s41421-018-0014-5. eCollection 2018. Cell Discov. 2018. PMID: 29619245 Free PMC article.

63

Collaborative Regulation of LRG1 by TGF-β1 and PPAR-β/δ Modulates Chronic Pressure Overload-Induced Cardiac Fibrosis.

Liu C, Lim ST, Teo MHY, Tan MSY, Kulkarni MD, Qiu B, Li A, Lal S, Dos Remedios CG, Tan NS, Wahli W, Ferenczi MA, Song W, Hong W, Wang X. Liu C, et al. Among authors: tan msy, tan ns. Circ Heart Fail. 2019 Dec;12(12):e005962. doi: 10.1161/CIRCHEARTFAILURE.119.005962. Epub 2019 Dec 13. Circ Heart Fail. 2019. PMID: 31830829

64

Bioinspired short peptide hydrogel for versatile encapsulation and controlled release of growth factor therapeutics.

Hiew SH, Wang JK, Koh K, Yang H, Bacha A, Lin J, Yip YS, Vos MIG, Chen L, Sobota RM, Tan NS, Tay CY, Miserez A. Hiew SH, et al. Among authors: tan ns. Acta Biomater. 2021 Dec;136:111-123. doi: 10.1016/j.actbio.2021.09.023. Epub 2021 Sep 20. Acta Biomater. 2021. PMID: 34551327

65

Neisseria species as pathobionts in bronchiectasis.

Li L, Mac Aogáin M, Xu T, Jaggi TK, Chan LLY, Qu J, Wei L, Liao S, Cheng HS, Keir HR, Dicker AJ, Tan KS, De Yun W, Koh MS, Ong TH, Lim AYH, Abisheganaden JA, Low TB, Hassan TM, Long X, Wark PAB, Oliver B, Drautz-Moses DI, Schuster SC, Tan NS, Fang M, Chalmers JD, Chotirmall SH. Li L, et al. Among authors: tan ks, tan ns. Cell Host Microbe. 2022 Sep 14;30(9):1311-1327.e8. doi: 10.1016/j.chom.2022.08.005. Cell Host Microbe. 2022. PMID: 36108613 Free article.

66

Mechano-Activated Cell Therapy for Accelerated Diabetic Wound Healing.

Shou Y, Le Z, Cheng HS, Liu Q, Ng YZ, Becker DL, Li X, Liu L, Xue C, Yeo NJY, Tan R, Low J, Kumar ARK, Wu KZ, Li H, Cheung C, Lim CT, Tan NS, Chen Y, Liu Z, Tay A. Shou Y, et al. Among authors: tan r, tan ns. Adv Mater. 2023 Nov;35(47):e2304638. doi: 10.1002/adma.202304638. Epub 2023 Oct 19. Adv Mater. 2023. PMID: 37681325

67

Label-Free Leukocyte Biophysical Profiling Using Impedance-Deformability Cytometry for Rapid Cardiovascular Risk Stratification.

He L, Tay HM, Chen F, Cheng HS, Wang L, Nam Q, Thannirmalai A, Gong L, Chung AJ, Tan NS, Li KHH, Dalan R, Wong SL, Hou HW. He L, et al. Among authors: tan ns. Adv Sci (Weinh). 2026 Feb;13(9):e16021. doi: 10.1002/advs.202516021. Epub 2025 Nov 28. Adv Sci (Weinh). 2026. PMID: 41313750 Free PMC article.

68

Differentiation of trophoblast giant cells and their metabolic functions are dependent on peroxisome proliferator-activated receptor beta/delta.

Nadra K, Anghel SI, Joye E, Tan NS, Basu-Modak S, Trono D, Wahli W, Desvergne B. Nadra K, et al. Among authors: tan ns. Mol Cell Biol. 2006 Apr;26(8):3266-81. doi: 10.1128/MCB.26.8.3266-3281.2006. Mol Cell Biol. 2006. PMID: 16581799 Free PMC article.

69

Nuclear receptor peroxisome proliferator activated receptor (PPAR) β/δ in skin wound healing and cancer.

Montagner A, Wahli W, Tan NS. Montagner A, et al. Among authors: tan ns. Eur J Dermatol. 2015 Apr;25 Suppl 1:4-11. doi: 10.1684/ejd.2014.2505. Eur J Dermatol. 2015. PMID: 26287030 Review.

70

A missing jigsaw within the hygiene hypothesis: Low-dose bisphenol A exposure attenuates lipopolysaccharide-induced asthma protection.

Wang M, Qu J, Yang J, Zhang T, Tan WR, Liao S, Chen X, Liu Y, Long X, Li X, Xia Y, Tan NS, Li L, Fang M. Wang M, et al. Among authors: tan wr, tan ns. PNAS Nexus. 2023 Nov 7;2(11):pgad312. doi: 10.1093/pnasnexus/pgad312. eCollection 2023 Nov. PNAS Nexus. 2023. PMID: 37954159 Free PMC article.

71

Titanium dioxide nanomaterials cause endothelial cell leakiness by disrupting the homophilic interaction of VE-cadherin.

Setyawati MI, Tay CY, Chia SL, Goh SL, Fang W, Neo MJ, Chong HC, Tan SM, Loo SC, Ng KW, Xie JP, Ong CN, Tan NS, Leong DT. Setyawati MI, et al. Among authors: tan sm, tan ns. Nat Commun. 2013;4:1673. doi: 10.1038/ncomms2655. Nat Commun. 2013. PMID: 23575677 Free article.

72

Critical roles of PPAR beta/delta in keratinocyte response to inflammation.

Tan NS, Michalik L, Noy N, Yasmin R, Pacot C, Heim M, Flühmann B, Desvergne B, Wahli W. Tan NS, et al. Genes Dev. 2001 Dec 15;15(24):3263-77. doi: 10.1101/gad.207501. Genes Dev. 2001. PMID: 11751632 Free PMC article.

73

Regulation of cell proliferation and migration by TAK1 via transcriptional control of von Hippel-Lindau tumor suppressor.

Tan SH, Pal M, Tan MJ, Wong MH, Tam FU, Teo JW, Chong HC, Tan CK, Goh YY, Tang MB, Cheung PC, Tan NS. Tan SH, et al. Among authors: tan mj, tan ck, tan ns. J Biol Chem. 2009 Jul 3;284(27):18047-58. doi: 10.1074/jbc.M109.002691. Epub 2009 May 6. J Biol Chem. 2009. PMID: 19419968 Free PMC article.

74

Nuclear hormone receptors and mouse skin homeostasis: implication of PPARbeta.

Michalik L, Desvergne B, Basu-Modak S, Tan NS, Wahli W. Michalik L, et al. Among authors: tan ns. Horm Res. 2000;54(5-6):263-8. doi: 10.1159/000053269. Horm Res. 2000. PMID: 11595815

75

Critical roles of the nuclear receptor PPARbeta (peroxisome-proliferator-activated receptor beta) in skin wound healing.

Tan NS, Michalik L, Di-Poï N, Desvergne B, Wahli W. Tan NS, et al. Biochem Soc Trans. 2004 Feb;32(Pt 1):97-102. doi: 10.1042/bst0320097. Biochem Soc Trans. 2004. PMID: 14748722 Review.

76

Elevation of adenylate energy charge by angiopoietin-like 4 enhances epithelial-mesenchymal transition by inducing 14-3-3γ expression.

Teo Z, Sng MK, Chan JSK, Lim MMK, Li Y, Li L, Phua T, Lee JYH, Tan ZW, Zhu P, Tan NS. Teo Z, et al. Among authors: tan zw, tan ns. Oncogene. 2017 Nov 16;36(46):6408-6419. doi: 10.1038/onc.2017.244. Epub 2017 Jul 24. Oncogene. 2017. PMID: 28745316 Free PMC article.

77

PAX4 loss of function increases diabetes risk by altering human pancreatic endocrine cell development.

Lau HH, Krentz NAJ, Abaitua F, Perez-Alcantara M, Chan JW, Ajeian J, Ghosh S, Lee Y, Yang J, Thaman S, Champon B, Sun H, Jha A, Hoon S, Tan NS, Gardner DS, Kao SL, Tai ES, Gloyn AL, Teo AKK. Lau HH, et al. Among authors: tan ns. Nat Commun. 2023 Sep 30;14(1):6119. doi: 10.1038/s41467-023-41860-z. Nat Commun. 2023. PMID: 37777536 Free PMC article.

78

Endothelial-immune crosstalk contributes to vasculopathy in nonalcoholic fatty liver disease.

Ng CY, Lee KL, Muthiah MD, Wu KX, Chioh FWJ, Tan K, Soon GST, Shabbir A, Loo WM, Low ZS, Chen Q, Wahli W, Tan NS, Ng HH, Dan YY, Cheung C. Ng CY, et al. Among authors: tan k, tan ns. EMBO Rep. 2022 Oct 6;23(10):e55871. doi: 10.15252/embr.202255871. EMBO Rep. 2022. PMID: 36200589 Free PMC article.

79

Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene.

Kersten S, Mandard S, Tan NS, Escher P, Metzger D, Chambon P, Gonzalez FJ, Desvergne B, Wahli W. Kersten S, et al. Among authors: tan ns. J Biol Chem. 2000 Sep 15;275(37):28488-93. doi: 10.1074/jbc.M004029200. J Biol Chem. 2000. PMID: 10862772 Free article.

80

In vivo activation of PPAR target genes by RXR homodimers.

IJpenberg A, Tan NS, Gelman L, Kersten S, Seydoux J, Xu J, Metzger D, Canaple L, Chambon P, Wahli W, Desvergne B. IJpenberg A, et al. Among authors: tan ns. EMBO J. 2004 May 19;23(10):2083-91. doi: 10.1038/sj.emboj.7600209. Epub 2004 Apr 22. EMBO J. 2004. PMID: 15103326 Free PMC article.

81

A STAT3-based gene signature stratifies glioma patients for targeted therapy.

Tan MSY, Sandanaraj E, Chong YK, Lim SW, Koh LWH, Ng WH, Tan NS, Tan P, Ang BT, Tang C. Tan MSY, et al. Among authors: tan p, tan ns. Nat Commun. 2019 Aug 9;10(1):3601. doi: 10.1038/s41467-019-11614-x. Nat Commun. 2019. PMID: 31399589 Free PMC article.

82

Bioactive sucralfate-based microneedles promote wound healing through reprogramming macrophages and protecting endogenous growth factors.

Le Z, Ramos MC, Shou Y, Li RR, Cheng HS, Jang CJ, Liu L, Xue C, Li X, Liu H, Lim CT, Tan NS, White AD, Charles CJ, Chen Y, Liu Z, Tay A. Le Z, et al. Among authors: tan ns. Biomaterials. 2024 Dec;311:122700. doi: 10.1016/j.biomaterials.2024.122700. Epub 2024 Jul 4. Biomaterials. 2024. PMID: 38996671

83

Forward-predictive SERS-based chemical taxonomy for untargeted structural elucidation of epimeric cerebrosides.

Tan EX, Leong SX, Liew WA, Phang IY, Ng JY, Tan NS, Lee YH, Ling XY. Tan EX, et al. Among authors: tan ns. Nat Commun. 2024 Mar 22;15(1):2582. doi: 10.1038/s41467-024-46838-z. Nat Commun. 2024. PMID: 38519477 Free PMC article.

84

Cancer-associated fibroblasts enact field cancerization by promoting extratumoral oxidative stress.

Chan JS, Tan MJ, Sng MK, Teo Z, Phua T, Choo CC, Li L, Zhu P, Tan NS. Chan JS, et al. Among authors: tan mj, tan ns. Cell Death Dis. 2017 Jan 19;8(1):e2562. doi: 10.1038/cddis.2016.492. Cell Death Dis. 2017. PMID: 28102840 Free PMC article.

85

The Interleukin-1 receptor antagonist is a direct target gene of PPARalpha in liver.

Stienstra R, Mandard S, Tan NS, Wahli W, Trautwein C, Richardson TA, Lichtenauer-Kaligis E, Kersten S, Müller M. Stienstra R, et al. Among authors: tan ns. J Hepatol. 2007 May;46(5):869-77. doi: 10.1016/j.jhep.2006.11.019. Epub 2006 Dec 26. J Hepatol. 2007. PMID: 17321000 Free article.

86

The direct peroxisome proliferator-activated receptor target fasting-induced adipose factor (FIAF/PGAR/ANGPTL4) is present in blood plasma as a truncated protein that is increased by fenofibrate treatment.

Mandard S, Zandbergen F, Tan NS, Escher P, Patsouris D, Koenig W, Kleemann R, Bakker A, Veenman F, Wahli W, Müller M, Kersten S. Mandard S, et al. Among authors: tan ns. J Biol Chem. 2004 Aug 13;279(33):34411-20. doi: 10.1074/jbc.M403058200. Epub 2004 Jun 9. J Biol Chem. 2004. PMID: 15190076 Free article.

87

Supercritical carbon dioxide extracted extracellular matrix material from adipose tissue.

Wang JK, Luo B, Guneta V, Li L, Foo SEM, Dai Y, Tan TTY, Tan NS, Choong C, Wong MTC. Wang JK, et al. Among authors: tan tty, tan ns. Mater Sci Eng C Mater Biol Appl. 2017 Jun 1;75:349-358. doi: 10.1016/j.msec.2017.02.002. Epub 2017 Feb 5. Mater Sci Eng C Mater Biol Appl. 2017. PMID: 28415472

88

Angiopoietin-like 4 Increases Pulmonary Tissue Leakiness and Damage during Influenza Pneumonia.

Li L, Chong HC, Ng SY, Kwok KW, Teo Z, Tan EHP, Choo CC, Seet JE, Choi HW, Buist ML, Chow VTK, Tan NS. Li L, et al. Among authors: tan ehp, tan ns. Cell Rep. 2015 Feb 10;10(5):654-663. doi: 10.1016/j.celrep.2015.01.011. Epub 2015 Feb 5. Cell Rep. 2015. PMID: 25660016 Free PMC article.

89

ANGPTL4 T266M variant is associated with reduced cancer invasiveness.

Tan ZW, Teo Z, Tan C, Choo CC, Loo WS, Song Y, Tam ZY, Ng SP, Koh HZ, Ng YS, Shochat SG, Yau YH, Zhu P, Tan NS. Tan ZW, et al. Among authors: tan c, tan ns. Biochim Biophys Acta Mol Cell Res. 2017 Oct;1864(10):1525-1536. doi: 10.1016/j.bbamcr.2017.06.010. Epub 2017 Jun 19. Biochim Biophys Acta Mol Cell Res. 2017. PMID: 28641978 Free article.

90

ANGPTL4 exacerbates pancreatitis by augmenting acinar cell injury through upregulation of C5a.

Jung KH, Son MK, Yan HH, Fang Z, Kim J, Kim SJ, Park JH, Lee JE, Yoon YC, Seo MS, Han BS, Ko S, Suh YJ, Lim JH, Lee DH, Teo Z, Wee JWK, Tan NS, Hong SS. Jung KH, et al. Among authors: tan ns. EMBO Mol Med. 2020 Aug 7;12(8):e11222. doi: 10.15252/emmm.201911222. Epub 2020 Jul 7. EMBO Mol Med. 2020. PMID: 32638512 Free PMC article.

91

The G0/G1 switch gene 2 is a novel PPAR target gene.

Zandbergen F, Mandard S, Escher P, Tan NS, Patsouris D, Jatkoe T, Rojas-Caro S, Madore S, Wahli W, Tafuri S, Müller M, Kersten S. Zandbergen F, et al. Among authors: tan ns. Biochem J. 2005 Dec 1;392(Pt 2):313-24. doi: 10.1042/BJ20050636. Biochem J. 2005. PMID: 16086669 Free PMC article.

92

PPARalpha governs glycerol metabolism.

Patsouris D, Mandard S, Voshol PJ, Escher P, Tan NS, Havekes LM, Koenig W, März W, Tafuri S, Wahli W, Müller M, Kersten S. Patsouris D, et al. Among authors: tan ns. J Clin Invest. 2004 Jul;114(1):94-103. doi: 10.1172/JCI20468. J Clin Invest. 2004. PMID: 15232616 Free PMC article.

93

Destabilization of β Cell FIT2 by saturated fatty acids alter lipid droplet numbers and contribute to ER stress and diabetes.

Zheng X, Ho QWC, Chua M, Stelmashenko O, Yeo XY, Muralidharan S, Torta F, Chew EGY, Lian MM, Foo JN, Jung S, Wong SH, Tan NS, Tong N, Rutter GA, Wenk MR, Silver DL, Berggren PO, Ali Y. Zheng X, et al. Among authors: tan ns. Proc Natl Acad Sci U S A. 2022 Mar 15;119(11):e2113074119. doi: 10.1073/pnas.2113074119. Epub 2022 Mar 7. Proc Natl Acad Sci U S A. 2022. PMID: 35254894 Free PMC article.

94

Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant mice.

Michalik L, Desvergne B, Tan NS, Basu-Modak S, Escher P, Rieusset J, Peters JM, Kaya G, Gonzalez FJ, Zakany J, Metzger D, Chambon P, Duboule D, Wahli W. Michalik L, et al. Among authors: tan ns. J Cell Biol. 2001 Aug 20;154(4):799-814. doi: 10.1083/jcb.200011148. J Cell Biol. 2001. PMID: 11514592 Free PMC article.

95

Selective cooperation between fatty acid binding proteins and peroxisome proliferator-activated receptors in regulating transcription.

Tan NS, Shaw NS, Vinckenbosch N, Liu P, Yasmin R, Desvergne B, Wahli W, Noy N. Tan NS, et al. Mol Cell Biol. 2002 Jul;22(14):5114-27. doi: 10.1128/MCB.22.14.5114-5127.2002. Mol Cell Biol. 2002. PMID: 12077340 Free PMC article.

96

Respiratory protein-generated reactive oxygen species as an antimicrobial strategy.

Jiang N, Tan NS, Ho B, Ding JL. Jiang N, et al. Among authors: tan ns. Nat Immunol. 2007 Oct;8(10):1114-22. doi: 10.1038/ni1501. Epub 2007 Aug 26. Nat Immunol. 2007. PMID: 17721536

97

ANGPTL4 modulates vascular junction integrity by integrin signaling and disruption of intercellular VE-cadherin and claudin-5 clusters.

Huang RL, Teo Z, Chong HC, Zhu P, Tan MJ, Tan CK, Lam CR, Sng MK, Leong DT, Tan SM, Kersten S, Ding JL, Li HY, Tan NS. Huang RL, et al. Among authors: tan sm, tan mj, tan ck, tan ns. Blood. 2011 Oct 6;118(14):3990-4002. doi: 10.1182/blood-2011-01-328716. Epub 2011 Aug 12. Blood. 2011. PMID: 21841165 Free article.

98

Angiopoietin-like 4 induces a β-catenin-mediated upregulation of ID3 in fibroblasts to reduce scar collagen expression.

Teo Z, Chan JSK, Chong HC, Sng MK, Choo CC, Phua GZM, Teo DJR, Zhu P, Choong C, Wong MTC, Tan NS. Teo Z, et al. Among authors: tan ns. Sci Rep. 2017 Jul 24;7(1):6303. doi: 10.1038/s41598-017-05869-x. Sci Rep. 2017. PMID: 28740178 Free PMC article.

99

Antibody Treatment against Angiopoietin-Like 4 Reduces Pulmonary Edema and Injury in Secondary Pneumococcal Pneumonia.

Li L, Foo BJW, Kwok KW, Sakamoto N, Mukae H, Izumikawa K, Mandard S, Quenot JP, Lagrost L, Teh WK, Singh Kohli G, Zhu P, Choi H, Buist ML, Seet JE, Yang L, He F, Kwong Chow VT, Tan NS. Li L, et al. Among authors: tan ns. mBio. 2019 Jun 4;10(3):e02469-18. doi: 10.1128/mBio.02469-18. mBio. 2019. PMID: 31164474 Free PMC article.

100

Glycogen synthase 2 is a novel target gene of peroxisome proliferator-activated receptors.

Mandard S, Stienstra R, Escher P, Tan NS, Kim I, Gonzalez FJ, Wahli W, Desvergne B, Müller M, Kersten S. Mandard S, et al. Among authors: tan ns. Cell Mol Life Sci. 2007 May;64(9):1145-57. doi: 10.1007/s00018-007-7006-1. Cell Mol Life Sci. 2007. PMID: 17437057 Free PMC article.

101

Elevated Plasma Angiopoietin-like 4 Protein Levels in Adult Patients with Dengue.

Khaing W, Lau SH, Thein TL, Tan NS, Alonso S, Vasoo S, Chia PY, Lye DCB, Leo YS, Chow VTK. Khaing W, et al. Among authors: tan ns. Viruses. 2025 Feb 6;17(2):226. doi: 10.3390/v17020226. Viruses. 2025. PMID: 40006981 Free PMC article.

102

Angiopoietin-like 4 Mediates Colonic Inflammation by Regulating Chemokine Transcript Stability via Tristetraprolin.

Phua T, Sng MK, Tan EH, Chee DS, Li Y, Wee JW, Teo Z, Chan JS, Lim MM, Tan CK, Zhu P, Arulampalam V, Tan NS. Phua T, et al. Among authors: tan eh, tan ck, tan ns. Sci Rep. 2017 Mar 13;7:44351. doi: 10.1038/srep44351. Sci Rep. 2017. PMID: 28287161 Free PMC article.

103

Reciprocal regulation of brain and muscle Arnt-like protein 1 and peroxisome proliferator-activated receptor alpha defines a novel positive feedback loop in the rodent liver circadian clock.

Canaple L, Rambaud J, Dkhissi-Benyahya O, Rayet B, Tan NS, Michalik L, Delaunay F, Wahli W, Laudet V. Canaple L, et al. Among authors: tan ns. Mol Endocrinol. 2006 Aug;20(8):1715-27. doi: 10.1210/me.2006-0052. Epub 2006 Mar 23. Mol Endocrinol. 2006. PMID: 16556735

104

Angiopoietin-like 4: a decade of research.

Zhu P, Goh YY, Chin HF, Kersten S, Tan NS. Zhu P, et al. Among authors: tan ns. Biosci Rep. 2012 Jun;32(3):211-9. doi: 10.1042/BSR20110102. Biosci Rep. 2012. PMID: 22458843 Free article. Review.

105

Feeding Angptl4^-/- mice trans fat promotes foam cell formation in mesenteric lymph nodes without leading to ascites.

Oteng AB, Bhattacharya A, Brodesser S, Qi L, Tan NS, Kersten S. Oteng AB, et al. Among authors: tan ns. J Lipid Res. 2017 Jun;58(6):1100-1113. doi: 10.1194/jlr.M074278. Epub 2017 Apr 15. J Lipid Res. 2017. PMID: 28412693 Free PMC article.

106

The Proinflammatory Secretome of Senescent Cells Can Be Controlled by a HIF2A-Dependent Upregulation and a FURIN-Dependent Cleavage of the ANGPTL4 Secreted Factor.

Makulyte G, Safwan-Zaiter H, Goehrig D, Huna A, Mangelinck A, Mikawa T, Palazzo A, Moudombi L, Medard JJ, Chanal M, Lecot P, Michallet MC, Gavard J, Adnot S, Dubus P, Kondoh H, Mann C, Tan NS, Bertolino P, Flaman JM, Bernard D. Makulyte G, et al. Among authors: tan ns. Aging Cell. 2026 Jan;25(1):e70307. doi: 10.1111/acel.70307. Epub 2025 Dec 5. Aging Cell. 2026. PMID: 41347893 Free PMC article.

107

Mobilization efficiency is critically regulated by fat via marrow PPARδ.

Suzuki T, Ishii S, Shinohara M, Kawano Y, Wakahashi K, Kawano H, Sada A, Minagawa K, Hamada M, Takahashi S, Furuyashiki T, Tan NS, Matsui T, Katayama Y. Suzuki T, et al. Among authors: tan ns. Haematologica. 2021 Jun 1;106(6):1671-1683. doi: 10.3324/haematol.2020.265751. Haematologica. 2021. PMID: 33538151 Free PMC article.

108

Matricellular proteins: a sticky affair with cancers.

Chong HC, Tan CK, Huang RL, Tan NS. Chong HC, et al. Among authors: tan ck, tan ns. J Oncol. 2012;2012:351089. doi: 10.1155/2012/351089. Epub 2012 Feb 9. J Oncol. 2012. PMID: 22481923 Free PMC article.

109

Emerging roles of angiopoietin-like 4 in human cancer.

Tan MJ, Teo Z, Sng MK, Zhu P, Tan NS. Tan MJ, et al. Among authors: tan ns. Mol Cancer Res. 2012 Jun;10(6):677-88. doi: 10.1158/1541-7786.MCR-11-0519. Epub 2012 Jun 1. Mol Cancer Res. 2012. PMID: 22661548 Free article. Review.

110

Angiopoietin-like 4 stimulates STAT3-mediated iNOS expression and enhances angiogenesis to accelerate wound healing in diabetic mice.

Chong HC, Chan JS, Goh CQ, Gounko NV, Luo B, Wang X, Foo S, Wong MT, Choong C, Kersten S, Tan NS. Chong HC, et al. Among authors: tan ns. Mol Ther. 2014 Sep;22(9):1593-604. doi: 10.1038/mt.2014.102. Epub 2014 Jun 6. Mol Ther. 2014. PMID: 24903577 Free PMC article.

111

Targeting nuclear receptors in cancer-associated fibroblasts as concurrent therapy to inhibit development of chemoresistant tumors.

Chan JSK, Sng MK, Teo ZQ, Chong HC, Twang JS, Tan NS. Chan JSK, et al. Among authors: tan ns. Oncogene. 2018 Jan 11;37(2):160-173. doi: 10.1038/onc.2017.319. Epub 2017 Sep 11. Oncogene. 2018. PMID: 28892046 Free PMC article.

112

Interpenetrating Network of Alginate-Human Adipose Extracellular Matrix Hydrogel for Islet Cells Encapsulation.

Wang JK, Cheam NMJ, Irvine SA, Tan NS, Venkatraman S, Tay CY. Wang JK, et al. Among authors: tan ns. Macromol Rapid Commun. 2020 Nov;41(21):e2000275. doi: 10.1002/marc.202000275. Epub 2020 Aug 19. Macromol Rapid Commun. 2020. PMID: 32815257

113

Loss of TAK1 increases cell traction force in a ROS-dependent manner to drive epithelial-mesenchymal transition of cancer cells.

Lam CR, Tan C, Teo Z, Tay CY, Phua T, Wu YL, Cai PQ, Tan LP, Chen X, Zhu P, Tan NS. Lam CR, et al. Among authors: tan c, tan lp, tan ns. Cell Death Dis. 2013 Oct 10;4(10):e848. doi: 10.1038/cddis.2013.339. Cell Death Dis. 2013. PMID: 24113182 Free PMC article.

114

Getting 'Smad' about obesity and diabetes.

Tan CK, Chong HC, Tan EH, Tan NS. Tan CK, et al. Among authors: tan eh, tan ns. Nutr Diabetes. 2012 Mar 5;2(3):e29. doi: 10.1038/nutd.2012.1. Nutr Diabetes. 2012. PMID: 23449528 Free PMC article.

115

Cancer-associated fibroblasts in tumor microenvironment - Accomplices in tumor malignancy.

Liao Z, Tan ZW, Zhu P, Tan NS. Liao Z, et al. Among authors: tan zw, tan ns. Cell Immunol. 2019 Sep;343:103729. doi: 10.1016/j.cellimm.2017.12.003. Epub 2018 Feb 13. Cell Immunol. 2019. PMID: 29397066 Review.

116

Fatty acid-inducible ANGPTL4 governs lipid metabolic response to exercise.

Catoire M, Alex S, Paraskevopulos N, Mattijssen F, Evers-van Gogh I, Schaart G, Jeppesen J, Kneppers A, Mensink M, Voshol PJ, Olivecrona G, Tan NS, Hesselink MK, Berbée JF, Rensen PC, Kalkhoven E, Schrauwen P, Kersten S. Catoire M, et al. Among authors: tan ns. Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):E1043-52. doi: 10.1073/pnas.1400889111. Epub 2014 Mar 3. Proc Natl Acad Sci U S A. 2014. PMID: 24591600 Free PMC article.

117

Migration and Phenotype Control of Human Dermal Fibroblasts by Electrospun Fibrous Substrates.

Chen H, Lui YS, Tan ZW, Lee JYH, Tan NS, Tan LP. Chen H, et al. Among authors: tan zw, tan lp, tan ns. Adv Healthc Mater. 2019 May;8(9):e1801378. doi: 10.1002/adhm.201801378. Epub 2019 Mar 22. Adv Healthc Mater. 2019. PMID: 30901162

118

Conditional knock out of N-WASP in keratinocytes causes skin barrier defects and atopic dermatitis-like inflammation.

Kalailingam P, Tan HB, Jain N, Sng MK, Chan JSK, Tan NS, Thanabalu T. Kalailingam P, et al. Among authors: tan hb, tan ns. Sci Rep. 2017 Aug 4;7(1):7311. doi: 10.1038/s41598-017-07125-8. Sci Rep. 2017. PMID: 28779153 Free PMC article.

119

An aPPARent Functional Consequence in Skeletal Muscle Physiology via Peroxisome Proliferator-Activated Receptors.

Phua WWT, Wong MXY, Liao Z, Tan NS. Phua WWT, et al. Among authors: tan ns. Int J Mol Sci. 2018 May 10;19(5):1425. doi: 10.3390/ijms19051425. Int J Mol Sci. 2018. PMID: 29747466 Free PMC article. Review.

120

Obesity-associated inflammation promotes angiogenesis and breast cancer via angiopoietin-like 4.

Kolb R, Kluz P, Tan ZW, Borcherding N, Bormann N, Vishwakarma A, Balcziak L, Zhu P, Davies BS, Gourronc F, Liu LZ, Ge X, Jiang BH, Gibson-Corley K, Klingelhutz A, Tan NS, Zhu Y, Sutterwala FS, Shen X, Zhang W. Kolb R, et al. Among authors: tan zw, tan ns. Oncogene. 2019 Mar;38(13):2351-2363. doi: 10.1038/s41388-018-0592-6. Epub 2018 Dec 5. Oncogene. 2019. PMID: 30518876 Free PMC article.

121

Transcription regulatory signals in the 5' and 3' regions of Oreochromis aureus ER gene.

Tan NS, Lam TJ, Ding JL. Tan NS, et al. Mol Cell Endocrinol. 1996 Oct 30;123(2):149-61. doi: 10.1016/s0303-7207(96)03911-1. Mol Cell Endocrinol. 1996. PMID: 8961252

122

Cutting Edge: Synchronization of IRF1, JunB, and C/EBPβ Activities during TLR3-TLR7 Cross-Talk Orchestrates Timely Cytokine Synergy in the Proinflammatory Response.

Liu Q, Zhu Y, Yong WK, Sze NS, Tan NS, Ding JL. Liu Q, et al. Among authors: tan ns. J Immunol. 2015 Aug 1;195(3):801-5. doi: 10.4049/jimmunol.1402358. Epub 2015 Jun 24. J Immunol. 2015. PMID: 26109639 Free PMC article.

123

Glioportal: a comprehensive transcriptomic resource unveiling ligand-mediated mesenchymal transition in glioblastoma.

Pang QY, Novera W, Koh LWH, Chong YK, Lim SW, Sim NL, Rizzetto S, Liu J, Lin X, Ang SYL, Ker JR, Wan KR, Low DCY, Cvijovic M, Goh WWB, Shao H, Tan NS, Yip S, Skanderup AMJ, Tang C, Tan P, Ang BT. Pang QY, et al. Among authors: tan p, tan ns. Neuro Oncol. 2025 Nov 1;27(11):2909-2926. doi: 10.1093/neuonc/noaf145. Neuro Oncol. 2025. PMID: 40518441 Free PMC article.

124

Materials Stiffness-Dependent Redox Metabolic Reprogramming of Mesenchymal Stem Cells for Secretome-Based Therapeutic Angiogenesis.

Yang H, Cheam NMJ, Cao H, Lee MKH, Sze SK, Tan NS, Tay CY. Yang H, et al. Among authors: tan ns. Adv Healthc Mater. 2019 Oct;8(20):e1900929. doi: 10.1002/adhm.201900929. Epub 2019 Sep 18. Adv Healthc Mater. 2019. PMID: 31532923

125

ANGPTL4 is produced by entero-endocrine cells in the human intestinal tract.

Alex S, Lichtenstein L, Dijk W, Mensink RP, Tan NS, Kersten S. Alex S, et al. Among authors: tan ns. Histochem Cell Biol. 2014 Apr;141(4):383-91. doi: 10.1007/s00418-013-1157-y. Epub 2013 Oct 19. Histochem Cell Biol. 2014. PMID: 24141811

126

A PDZ Protein GIPC3 Positively Modulates Hedgehog Signaling and Melanoma Growth.

Patmanathan SN, Tong BT, Teo JHJ, Ting YZJ, Tan NS, Sim SHK, Ta YC, Woo WM. Patmanathan SN, et al. Among authors: tan ns. J Invest Dermatol. 2022 Jan;142(1):179-188.e4. doi: 10.1016/j.jid.2021.04.033. Epub 2021 Jul 2. J Invest Dermatol. 2022. PMID: 34224745 Free article.

127

Emerging nanosensor platforms and machine learning strategies toward rapid, point-of-need small-molecule metabolite detection and monitoring.

Leong SX, Leong YX, Koh CSL, Tan EX, Nguyen LBT, Chen JRT, Chong C, Pang DWC, Sim HYF, Liang X, Tan NS, Ling XY. Leong SX, et al. Among authors: tan ex, tan ns. Chem Sci. 2022 Sep 13;13(37):11009-11029. doi: 10.1039/d2sc02981b. eCollection 2022 Sep 28. Chem Sci. 2022. PMID: 36320477 Free PMC article. Review.

128

Sustained-releasing hollow microparticles with dual-anticancer drugs elicit greater shrinkage of tumor spheroids.

Baek JS, Choo CC, Tan NS, Loo SCJ. Baek JS, et al. Among authors: tan ns. Oncotarget. 2017 Aug 24;8(46):80841-80852. doi: 10.18632/oncotarget.20591. eCollection 2017 Oct 6. Oncotarget. 2017. PMID: 29113348 Free PMC article.

129

Nox4-dependent ROS modulation by amino endoperoxides to induce apoptosis in cancer cells.

Zhu P, Tong BM, Wang R, Chen JP, Foo S, Chong HC, Wang XL, Ang GY, Chiba S, Tan NS. Zhu P, et al. Among authors: tan ns. Cell Death Dis. 2013 Mar 21;4(3):e552. doi: 10.1038/cddis.2013.68. Cell Death Dis. 2013. PMID: 23519121 Free PMC article.

130

CD163 and IgG codefend against cytotoxic hemoglobin via autocrine and paracrine mechanisms.

Subramanian K, Du R, Tan NS, Ho B, Ding JL. Subramanian K, et al. Among authors: tan ns. J Immunol. 2013 May 15;190(10):5267-78. doi: 10.4049/jimmunol.1202648. Epub 2013 Apr 15. J Immunol. 2013. PMID: 23589619 Free article.

131

SMAD3 deficiency promotes inflammatory aortic aneurysms in angiotensin II-infused mice via activation of iNOS.

Tan CK, Tan EH, Luo B, Huang CL, Loo JS, Choong C, Tan NS. Tan CK, et al. Among authors: tan eh, tan ns. J Am Heart Assoc. 2013 Jun 19;2(3):e000269. doi: 10.1161/JAHA.113.000269. J Am Heart Assoc. 2013. PMID: 23782924 Free PMC article.

132

Chelating Phosphine-N-Heterocyclic Carbene Platinum Complexes via Catalytic Asymmetric Hydrophosphination and Their Cytotoxicity Toward MKN74 and MCF7 Cancer Cell Lines.

Seah JWK, Lee JXT, Li Y, Pullarkat SA, Tan NS, Leung PH. Seah JWK, et al. Among authors: tan ns. Inorg Chem. 2021 Nov 15;60(22):17276-17287. doi: 10.1021/acs.inorgchem.1c02625. Epub 2021 Oct 28. Inorg Chem. 2021. PMID: 34709031

133

Characterisation of serum progesterone and progesterone-induced blocking factor (PIBF) levels across trimesters in healthy pregnant women.

Lim MK, Ku CW, Tan TC, Lee YHJ, Allen JC, Tan NS. Lim MK, et al. Among authors: tan tc, tan ns. Sci Rep. 2020 Mar 2;10(1):3840. doi: 10.1038/s41598-020-59452-y. Sci Rep. 2020. PMID: 32123187 Free PMC article.

134

Myostatin-null mice exhibit delayed skin wound healing through the blockade of transforming growth factor-β signaling by decorin.

Zhang C, Tan CK, McFarlane C, Sharma M, Tan NS, Kambadur R. Zhang C, et al. Among authors: tan ck, tan ns. Am J Physiol Cell Physiol. 2012 Apr 15;302(8):C1213-25. doi: 10.1152/ajpcell.00179.2011. Epub 2012 Jan 25. Am J Physiol Cell Physiol. 2012. PMID: 22277753 Free article.

135

Glucagon-like peptide-1 receptor agonists (GLP-1RAs) in dermatology: cutaneous adverse events and emerging efficacy in inflammatory skin diseases.

Ho MJ, Liew CF, Tan NS, Morita A, Oon HH. Ho MJ, et al. Among authors: tan ns. Expert Rev Clin Immunol. 2026 Apr 30:1-18. doi: 10.1080/1744666X.2026.2665732. Online ahead of print. Expert Rev Clin Immunol. 2026. PMID: 42043978 Review.

136

PARP4 interacts with hnRNPM to regulate splicing during lung cancer progression.

Lee YF, Phua CZJ, Yuan J, Zhang B, Lee MY, Kannan S, Chiu YHJ, Koh CWQ, Yap CK, Lim EKH, Chen J, Lim Y, Lee JJH, Skanderup AJ, Wang Z, Zhai W, Tan NS, Verma CS, Tay Y, Tan DSW, Tam WL. Lee YF, et al. Among authors: tan dsw, tan ns. Genome Med. 2024 Jul 22;16(1):91. doi: 10.1186/s13073-024-01328-1. Genome Med. 2024. PMID: 39034402 Free PMC article.

137

Culturing fibroblasts in 3D human hair keratin hydrogels.

Wang S, Wang Z, Foo SE, Tan NS, Yuan Y, Lin W, Zhang Z, Ng KW. Wang S, et al. Among authors: tan ns. ACS Appl Mater Interfaces. 2015 Mar 11;7(9):5187-98. doi: 10.1021/acsami.5b00854. Epub 2015 Feb 25. ACS Appl Mater Interfaces. 2015. PMID: 25690726

138

Mechanoregulation of Cancer-Associated Fibroblast Phenotype in Three-Dimensional Interpenetrating Hydrogel Networks.

Cao H, Lee MKH, Yang H, Sze SK, Tan NS, Tay CY. Cao H, et al. Among authors: tan ns. Langmuir. 2019 Jun 11;35(23):7487-7495. doi: 10.1021/acs.langmuir.8b02649. Epub 2018 Dec 7. Langmuir. 2019. PMID: 30480453

139

Noninvasive and Point-of-Care Surface-Enhanced Raman Scattering (SERS)-Based Breathalyzer for Mass Screening of Coronavirus Disease 2019 (COVID-19) under 5 min.

Leong SX, Leong YX, Tan EX, Sim HYF, Koh CSL, Lee YH, Chong C, Ng LS, Chen JRT, Pang DWC, Nguyen LBT, Boong SK, Han X, Kao YC, Chua YH, Phan-Quang GC, Phang IY, Lee HK, Abdad MY, Tan NS, Ling XY. Leong SX, et al. Among authors: tan ex, tan ns. ACS Nano. 2022 Feb 22;16(2):2629-2639. doi: 10.1021/acsnano.1c09371. Epub 2022 Jan 18. ACS Nano. 2022. PMID: 35040314

140

Probing for protein-protein interactions during cell migration: limitations and challenges.

Chan JS, Teo Z, Sng MK, Tan NS. Chan JS, et al. Among authors: tan ns. Histol Histopathol. 2014 Aug;29(8):965-76. doi: 10.14670/HH-29.965. Epub 2014 Feb 19. Histol Histopathol. 2014. PMID: 24549517 Review.

141

Spontaneous miscarriage in first trimester pregnancy is associated with altered urinary metabolite profile.

Ku CW, Tan ZW, Lim MK, Tam ZY, Lin CH, Ng SP, Allen JC, Lek SM, Tan TC, Tan NS. Ku CW, et al. Among authors: tan tc, tan zw, tan ns. BBA Clin. 2017 Aug 19;8:48-55. doi: 10.1016/j.bbacli.2017.07.003. eCollection 2017 Dec. BBA Clin. 2017. PMID: 28879096 Free PMC article.

142

EZH2 functional dichotomy in reactive oxygen species-stratified glioblastoma.

Koh LWH, Pang QY, Novera W, Lim SW, Chong YK, Liu J, Ang SYL, Loh RWY, Shao H, Ching J, Wang Y, Yip S, Tan P, Li S, Low DCY, Phelan A, Rosser G, Tan NS, Tang C, Ang BT. Koh LWH, et al. Among authors: tan p, tan ns. Neuro Oncol. 2025 Feb 10;27(2):398-414. doi: 10.1093/neuonc/noae206. Neuro Oncol. 2025. PMID: 39373211 Free PMC article.

143

Calcium release from hydroxyapatite particles influences breast cancer cell osteomimicry and osteolytic behaviors in bone metastases.

Castro NM, Wang JK, Tergaonkar V, Tan NS, Tanner KE, Tay CY. Castro NM, et al. Among authors: tan ns. Biofabrication. 2025 Nov 25;18(1). doi: 10.1088/1758-5090/ae1878. Biofabrication. 2025. PMID: 41151157

144

Recellularization of decellularized adipose tissue-derived stem cells: role of the cell-secreted extracellular matrix in cellular differentiation.

Guneta V, Zhou Z, Tan NS, Sugii S, Wong MTC, Choong C. Guneta V, et al. Among authors: tan ns. Biomater Sci. 2017 Dec 19;6(1):168-178. doi: 10.1039/c7bm00695k. Biomater Sci. 2017. PMID: 29167844

145

Engineering a novel secretion signal for cross-host recombinant protein expression.

Tan NS, Ho B, Ding JL. Tan NS, et al. Protein Eng. 2002 Apr;15(4):337-45. doi: 10.1093/protein/15.4.337. Protein Eng. 2002. PMID: 11983935

146

Secreted M-ficolin anchors onto monocyte transmembrane G protein-coupled receptor 43 and cross talks with plasma C-reactive protein to mediate immune signaling and regulate host defense.

Zhang J, Yang L, Ang Z, Yoong SL, Tran TT, Anand GS, Tan NS, Ho B, Ding JL. Zhang J, et al. Among authors: tan ns. J Immunol. 2010 Dec 1;185(11):6899-910. doi: 10.4049/jimmunol.1001225. Epub 2010 Oct 29. J Immunol. 2010. PMID: 21037097

147

Natural IgG antibodies provide innate protection against ficolin-opsonized bacteria.

Panda S, Zhang J, Tan NS, Ho B, Ding JL. Panda S, et al. Among authors: tan ns. EMBO J. 2013 Nov 13;32(22):2905-19. doi: 10.1038/emboj.2013.199. Epub 2013 Sep 3. EMBO J. 2013. PMID: 24002211 Free PMC article.

148

Definition of endotoxin binding sites in horseshoe crab factor C recombinant sushi proteins and neutralization of endotoxin by sushi peptides.

Tan NS, Ng ML, Yau YH, Chong PK, Ho B, Ding JL. Tan NS, et al. FASEB J. 2000 Sep;14(12):1801-13. doi: 10.1096/fj.99-0866com. FASEB J. 2000. PMID: 10973930

149

Fabrication and drug release study of double-layered microparticles of various sizes.

Lee WL, Seh YC, Widjaja E, Chong HC, Tan NS, Loo SC. Lee WL, et al. Among authors: tan ns. J Pharm Sci. 2012 Aug;101(8):2787-97. doi: 10.1002/jps.23191. Epub 2012 May 9. J Pharm Sci. 2012. PMID: 22573569

150

Downregulation of oncogenic RAS and c-Myc expression in MOLT-4 leukaemia cells by a salicylaldehyde semicarbazone copper(II) complex.

Goh YY, Yan YK, Tan NS, Goh SA, Li S, Teoh YC, Lee PP. Goh YY, et al. Among authors: tan ns. Sci Rep. 2016 Nov 14;6:36868. doi: 10.1038/srep36868. Sci Rep. 2016. PMID: 27841290 Free PMC article.

151

Multiplex Surface-Enhanced Raman Scattering Identification and Quantification of Urine Metabolites in Patient Samples within 30 min.

Kao YC, Han X, Lee YH, Lee HK, Phan-Quang GC, Lay CL, Sim HYF, Phua VJX, Ng LS, Ku CW, Tan TC, Phang IY, Tan NS, Ling XY. Kao YC, et al. Among authors: tan tc, tan ns. ACS Nano. 2020 Feb 25;14(2):2542-2552. doi: 10.1021/acsnano.0c00515. Epub 2020 Feb 17. ACS Nano. 2020. PMID: 32049493

152

N-WASP Attenuates Cell Proliferation and Migration through ERK2-Dependent Enhanced Expression of TXNIP.

Chung YJ, Salvi A, Kalailingam P, Alnawaz M, Tan SH, Pan JY, Tan NS, Thanabalu T. Chung YJ, et al. Among authors: tan sh, tan ns. Biology (Basel). 2022 Apr 11;11(4):582. doi: 10.3390/biology11040582. Biology (Basel). 2022. PMID: 35453780 Free PMC article.

153

Endothelial cell thrombogenicity is reduced by ATRP-mediated grafting of gelatin onto PCL surfaces.

Xiong GM , Yuan S , Tan CK , Wang JK , Liu Y , Yang Tan TT , Tan NS , Choong C . Xiong GM , et al. Among authors: tan ck, tan ns. J Mater Chem B. 2014 Feb 7;2(5):485-493. doi: 10.1039/c3tb20760a. Epub 2013 Dec 10. J Mater Chem B. 2014. PMID: 32261529

154

Hydrogel Effects Rapid Biofilm Debridement with ex situ Contact-Kill to Eliminate Multidrug Resistant Bacteria in vivo.

Yeo CK, Vikhe YS, Li P, Guo Z, Greenberg P, Duan H, Tan NS, Chan-Park MB. Yeo CK, et al. Among authors: tan ns. ACS Appl Mater Interfaces. 2018 Jun 20;10(24):20356-20367. doi: 10.1021/acsami.8b06262. Epub 2018 Jun 7. ACS Appl Mater Interfaces. 2018. PMID: 29806938 Free article.

155

Nanoparticles of Short Cationic Peptidopolysaccharide Self-Assembled by Hydrogen Bonding with Antibacterial Effect against Multidrug-Resistant Bacteria.

Hou Z, Shankar YV, Liu Y, Ding F, Subramanion JL, Ravikumar V, Zamudio-Vázquez R, Keogh D, Lim H, Tay MYF, Bhattacharjya S, Rice SA, Shi J, Duan H, Liu XW, Mu Y, Tan NS, Tam KC, Pethe K, Chan-Park MB. Hou Z, et al. Among authors: tan ns. ACS Appl Mater Interfaces. 2017 Nov 8;9(44):38288-38303. doi: 10.1021/acsami.7b12120. Epub 2017 Oct 26. ACS Appl Mater Interfaces. 2017. PMID: 29028315

156

Supramolecular nanoparticle carriers self-assembled from cyclodextrin- and adamantane-functionalized polyacrylates for tumor-targeted drug delivery.

Ang CY , Tan SY , Wang X , Zhang Q , Khan M , Bai L , Tamil Selvan S , Ma X , Zhu L , Nguyen KT , Tan NS , Zhao Y . Ang CY , et al. Among authors: tan sy, tan ns. J Mater Chem B. 2014 Apr 7;2(13):1879-1890. doi: 10.1039/c3tb21325k. Epub 2014 Feb 21. J Mater Chem B. 2014. PMID: 32261524

157

From flab to fab: transforming surgical waste into an effective bioactive coating material.

Luo B, Yuan S, Foo SE, Wong MT, Lim TC, Tan NS, Choong C. Luo B, et al. Among authors: tan ns. Adv Healthc Mater. 2015 Mar 11;4(4):613-20. doi: 10.1002/adhm.201400514. Epub 2014 Nov 26. Adv Healthc Mater. 2015. PMID: 25424903

158

Early controlled release of peroxisome proliferator-activated receptor β/δ agonist GW501516 improves diabetic wound healing through redox modulation of wound microenvironment.

Wang X, Sng MK, Foo S, Chong HC, Lee WL, Tang MB, Ng KW, Luo B, Choong C, Wong MT, Tong BM, Chiba S, Loo SC, Zhu P, Tan NS. Wang X, et al. Among authors: tan ns. J Control Release. 2015 Jan 10;197:138-47. doi: 10.1016/j.jconrel.2014.11.001. Epub 2014 Nov 7. J Control Release. 2015. PMID: 25449811

159

Highly selective anti-cancer properties of ester functionalized enantiopure dinuclear gold(I)-diphosphine.

Li BB, Jia YX, Zhu PC, Chew RJ, Li Y, Tan NS, Leung PH. Li BB, et al. Among authors: tan ns. Eur J Med Chem. 2015 Jun 15;98:250-5. doi: 10.1016/j.ejmech.2015.05.027. Epub 2015 May 19. Eur J Med Chem. 2015. PMID: 26047407

160

Modulated TRPC1 Expression Predicts Sensitivity of Breast Cancer to Doxorubicin and Magnetic Field Therapy: Segue Towards a Precision Medicine Approach.

Tai YK, Chan KKW, Fong CHH, Ramanan S, Yap JLY, Yin JN, Yip YS, Tan WR, Koh APF, Tan NS, Chan CW, Huang RYJ, Li JZ, Fröhlich J, Franco-Obregón A. Tai YK, et al. Among authors: tan wr, tan ns. Front Oncol. 2022 Jan 24;11:783803. doi: 10.3389/fonc.2021.783803. eCollection 2021. Front Oncol. 2022. PMID: 35141145 Free PMC article.

161

Therapy-Induced Senescence Contributes to the Efficacy of Abemaciclib in Patients with Dedifferentiated Liposarcoma.

Gleason CE, Dickson MA, Klein Dooley ME, Antonescu CR, Gularte-Mérida R, Benitez M, Delgado JI, Kataru RP, Tan MWY, Bradic M, Adamson TE, Seier K, Richards AL, Palafox M, Chan E, D'Angelo SP, Gounder MM, Keohan ML, Kelly CM, Chi P, Movva S, Landa J, Crago AM, Donoghue MTA, Qin LX, Serra V, Turkekul M, Barlas A, Firester DM, Manova-Todorova K, Mehrara BJ, Kovatcheva M, Tan NS, Singer S, Tap WD, Koff A. Gleason CE, et al. Among authors: tan mwy, tan ns. Clin Cancer Res. 2024 Feb 16;30(4):703-718. doi: 10.1158/1078-0432.CCR-23-2378. Clin Cancer Res. 2024. PMID: 37695642 Free PMC article.

162

Bioactivated protein-based porous microcarriers for tissue engineering applications.

Luo B , Loh QL , Chong Wong MT , Tan NS , Choong C . Luo B , et al. Among authors: tan ns. J Mater Chem B. 2014 Nov 28;2(44):7795-7803. doi: 10.1039/c4tb00846d. Epub 2014 Oct 15. J Mater Chem B. 2014. PMID: 32261917

163

Fabrication and characterization of a novel crosslinked human keratin-alginate sponge.

Hartrianti P, Nguyen LTH, Johanes J, Chou SM, Zhu P, Tan NS, Tang MBY, Ng KW. Hartrianti P, et al. Among authors: tan ns. J Tissue Eng Regen Med. 2017 Sep;11(9):2590-2602. doi: 10.1002/term.2159. Epub 2016 Apr 25. J Tissue Eng Regen Med. 2017. PMID: 27109145

164

Corrigendum: Modulated TRPC1 Expression Predicts Sensitivity of Breast Cancer to Doxorubicin and Magnetic Field Therapy: Segue Towards a Precision Medicine Approach.

Tai YK, Chan KKW, Fong CHH, Ramanan S, Yap JLY, Yin JN, Yip YS, Tan WR, Koh APF, Tan NS, Chan CW, Huang RYJ, Li JZ, Fröhlich J, Franco-Obregón A. Tai YK, et al. Among authors: tan wr, tan ns. Front Oncol. 2022 Apr 20;12:892408. doi: 10.3389/fonc.2022.892408. eCollection 2022. Front Oncol. 2022. PMID: 35515135 Free PMC article.

165

Perylene-derived single-component organic nanoparticles with tunable emission: efficient anticancer drug carriers with real-time monitoring of drug release.

Jana A, Nguyen KT, Li X, Zhu P, Tan NS, Ågren H, Zhao Y. Jana A, et al. Among authors: tan ns. ACS Nano. 2014 Jun 24;8(6):5939-52. doi: 10.1021/nn501073x. Epub 2014 May 16. ACS Nano. 2014. PMID: 24824959

166

A novel piscine vitellogenin gene: structural and functional analyses of estrogen-inducible promoter.

Teo BY, Tan NS, Lim EH, Lam TJ, Ding JL. Teo BY, et al. Among authors: tan ns. Mol Cell Endocrinol. 1998 Nov 25;146(1-2):103-20. doi: 10.1016/s0303-7207(98)00191-9. Mol Cell Endocrinol. 1998. PMID: 10022768

167

Anti-cAngptl4 Ab-conjugated N-TiO(2) /NaYF(4) :Yb,Tm nanocomposite for near infrared-triggered drug release and enhanced targeted cancer cell ablation.

Xu QC, Zhang Y, Tan MJ, Liu Y, Yuan S, Choong C, Tan NS, Tan TT. Xu QC, et al. Among authors: tan tt, tan mj, tan ns. Adv Healthc Mater. 2012 Jul;1(4):470-4. doi: 10.1002/adhm.201200055. Epub 2012 Jun 4. Adv Healthc Mater. 2012. PMID: 23184779

168

Overexpression of angiopoietin-like protein 4 protects against atherosclerosis development.

Georgiadi A, Wang Y, Stienstra R, Tjeerdema N, Janssen A, Stalenhoef A, van der Vliet JA, de Roos A, Tamsma JT, Smit JW, Tan NS, Müller M, Rensen PC, Kersten S. Georgiadi A, et al. Among authors: tan ns. Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):1529-37. doi: 10.1161/ATVBAHA.113.301698. Epub 2013 May 2. Arterioscler Thromb Vasc Biol. 2013. PMID: 23640487

169

Inhibition of 3-D tumor spheroids by timed-released hydrophilic and hydrophobic drugs from multilayered polymeric microparticles.

Lee WL, Guo WM, Ho VH, Saha A, Chong HC, Tan NS, Widjaja E, Tan EY, Loo SC. Lee WL, et al. Among authors: tan ey, tan ns. Small. 2014 Oct 15;10(19):3986-96. doi: 10.1002/smll.201400536. Epub 2014 Jun 20. Small. 2014. PMID: 24947558

170

Human and mouse monocytes display distinct signalling and cytokine profiles upon stimulation with FFAR2/FFAR3 short-chain fatty acid receptor agonists.

Ang Z, Er JZ, Tan NS, Lu J, Liou YC, Grosse J, Ding JL. Ang Z, et al. Among authors: tan ns. Sci Rep. 2016 Sep 26;6:34145. doi: 10.1038/srep34145. Sci Rep. 2016. PMID: 27667443 Free PMC article.

171

Potent-By-Design: Amino Acids Mimicking Porous Nanotherapeutics with Intrinsic Anticancer Targeting Properties.

Wu Z, Lim HK, Tan SJ, Gautam A, Hou HW, Ng KW, Tan NS, Tay CY. Wu Z, et al. Among authors: tan sj, tan ns. Small. 2020 Aug;16(34):e2003757. doi: 10.1002/smll.202003757. Epub 2020 Jul 19. Small. 2020. PMID: 32686344

172

GREB1: An evolutionarily conserved protein with a glycosyltransferase domain links ERα glycosylation and stability to cancer.

Shin EM, Huynh VT, Neja SA, Liu CY, Raju A, Tan K, Tan NS, Gunaratne J, Bi X, Iyer LM, Aravind L, Tergaonkar V. Shin EM, et al. Among authors: tan k, tan ns. Sci Adv. 2021 Mar 17;7(12):eabe2470. doi: 10.1126/sciadv.abe2470. Print 2021 Mar. Sci Adv. 2021. PMID: 33731348 Free PMC article.

173

Serum progesterone distribution in normal pregnancies compared to pregnancies complicated by threatened miscarriage from 5 to 13 weeks gestation: a prospective cohort study.

Ku CW, Allen JC Jr, Lek SM, Chia ML, Tan NS, Tan TC. Ku CW, et al. Among authors: tan tc, tan ns. BMC Pregnancy Childbirth. 2018 Sep 5;18(1):360. doi: 10.1186/s12884-018-2002-z. BMC Pregnancy Childbirth. 2018. PMID: 30185145 Free PMC article.

174

Comparative Study of Adipose-Derived Stem Cells From Abdomen and Breast.

Guneta V, Tan NS, Sugii S, Lim TC, Wong TC, Choong C. Guneta V, et al. Among authors: tan ns. Ann Plast Surg. 2016 May;76(5):569-75. doi: 10.1097/SAP.0000000000000797. Ann Plast Surg. 2016. PMID: 27070348

175

Multi-Drug-Loaded Microcapsules with Controlled Release for Management of Parkinson's Disease.

Baek JS, Choo CC, Qian C, Tan NS, Shen Z, Loo SC. Baek JS, et al. Among authors: tan ns. Small. 2016 Jul;12(27):3712-22. doi: 10.1002/smll.201600067. Epub 2016 Jun 2. Small. 2016. PMID: 27253884

176

Evidence for the ancient origin of the NF-kappaB/IkappaB cascade: its archaic role in pathogen infection and immunity.

Wang XW, Tan NS, Ho B, Ding JL. Wang XW, et al. Among authors: tan ns. Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4204-9. doi: 10.1073/pnas.0507044103. Epub 2006 Mar 6. Proc Natl Acad Sci U S A. 2006. PMID: 16537509 Free PMC article.

177

The Polyamine Putrescine Promotes Human Epidermal Melanogenesis.

Sridharan A, Shi M, Leo VI, Subramaniam N, Lim TC, Uemura T, Igarashi K, Tien Guan ST, Tan NS, Vardy LA. Sridharan A, et al. Among authors: tan ns. J Invest Dermatol. 2020 Oct;140(10):2032-2040.e1. doi: 10.1016/j.jid.2020.02.009. Epub 2020 Feb 28. J Invest Dermatol. 2020. PMID: 32119868 Free article.

178

Conditional knockout of N-WASP in mouse fibroblast caused keratinocyte hyper proliferation and enhanced wound closure.

Jain N, Kalailingam P, Tan KW, Tan HB, Sng MK, Chan JS, Tan NS, Thanabalu T. Jain N, et al. Among authors: tan kw, tan hb, tan ns. Sci Rep. 2016 Dec 2;6:38109. doi: 10.1038/srep38109. Sci Rep. 2016. PMID: 27909303 Free PMC article.

179

Modular arrangement and secretion of a multidomain serine protease. Evidence for involvement of proline-rich region and N-glycans in the secretion pathway.

Wang J, Tan NS, Ho B, Ding JL. Wang J, et al. Among authors: tan ns. J Biol Chem. 2002 Sep 27;277(39):36363-72. doi: 10.1074/jbc.M202837200. Epub 2002 Jun 27. J Biol Chem. 2002. PMID: 12089146 Free article.

180

High-affinity LPS binding domain(s) in recombinant factor C of a horseshoe crab neutralizes LPS-induced lethality.

Tan NS, Ho B, Ding JL. Tan NS, et al. FASEB J. 2000 May;14(7):859-70. doi: 10.1096/fasebj.14.7.859. FASEB J. 2000. PMID: 10783139

181

A 3D biomimetic model of tissue stiffness interface for cancer drug testing.

Lam CR, Wong HK, Nai S, Chua CK, Tan NS, Tan LP. Lam CR, et al. Among authors: tan lp, tan ns. Mol Pharm. 2014 Jul 7;11(7):2016-21. doi: 10.1021/mp500059q. Epub 2014 Apr 22. Mol Pharm. 2014. PMID: 24754837

182

Nanomechanically Visualizing Drug-Cell Interaction at the Early Stage of Chemotherapy.

Wu YL, Engl W, Hu B, Cai P, Leow WR, Tan NS, Lim CT, Chen X. Wu YL, et al. Among authors: tan ns. ACS Nano. 2017 Jul 25;11(7):6996-7005. doi: 10.1021/acsnano.7b02376. Epub 2017 May 30. ACS Nano. 2017. PMID: 28530823

183

Photocurable platelet rich plasma bioadhesives.

Singh M, Nanda HS, Lee JYH, Wang JK, Tan NS, Steele TWJ. Singh M, et al. Among authors: tan ns. Acta Biomater. 2020 Nov;117:133-141. doi: 10.1016/j.actbio.2020.09.030. Epub 2020 Sep 20. Acta Biomater. 2020. PMID: 32966923

184

Comparative study of adipose-derived stem cells and bone marrow-derived stem cells in similar microenvironmental conditions.

Guneta V, Tan NS, Chan SK, Tanavde V, Lim TC, Wong TC, Choong C. Guneta V, et al. Among authors: tan ns. Exp Cell Res. 2016 Nov 1;348(2):155-164. doi: 10.1016/j.yexcr.2016.09.012. Epub 2016 Sep 19. Exp Cell Res. 2016. PMID: 27658569

185

Delivery of doxorubicin and paclitaxel from double-layered microparticles: The effects of layer thickness and dual-drug vs. single-drug loading.

Lee WL, Guo WM, Ho VHB, Saha A, Chong HC, Tan NS, Tan EY, Loo SCJ. Lee WL, et al. Among authors: tan ey, tan ns. Acta Biomater. 2015 Nov;27:53-65. doi: 10.1016/j.actbio.2015.08.051. Epub 2015 Sep 1. Acta Biomater. 2015. PMID: 26340886

186

Novel approach using serum progesterone as a triage to guide management of patients with threatened miscarriage: a prospective cohort study.

Tan TC, Ku CW, Kwek LK, Lee KW, Zhang X, Allen JC Jr, Zhang VR, Tan NS. Tan TC, et al. Among authors: tan ns. Sci Rep. 2020 Jun 4;10(1):9153. doi: 10.1038/s41598-020-66155-x. Sci Rep. 2020. PMID: 32499581 Free PMC article.

187

Unrecognized ciliary motility disorders in neutrophilic severe asthma exacerbations.

Thawanaphong S, Gonzalez-Bravo L, Radford K, Kjarsgaard M, Venegas Garrido C, Fedosenko S, Ho T, Dyment L, Tan NS, Zhang K, Adatia A, Mukherjee M, Dolovich M, Nair P. Thawanaphong S, et al. Among authors: tan ns. Allergy Asthma Clin Immunol. 2026 May 8. doi: 10.1186/s13223-026-01041-1. Online ahead of print. Allergy Asthma Clin Immunol. 2026. PMID: 42104487 Free article.

188

Nanoparticles for autoimmune diseases: advancing diagnostics and therapeutic solutions.

Ong EXN, Ng CYJ, Cao LL, Li X, Li PP, Tan NS, Liao Z, Zhao Y. Ong EXN, et al. Among authors: tan ns. Acta Pharmacol Sin. 2026 May 4. doi: 10.1038/s41401-026-01794-w. Online ahead of print. Acta Pharmacol Sin. 2026. PMID: 42082628 Review.

189

Inhaled Angiopoietin-Like 4 Antisense Oligonucleotide Therapy for Lung Injury and Fibrosis.

Fan H, Tan Y, Zhang J, Liu X, Qu J, Chua D, Cheng HS, Kim JHS, Liu YX, Qin C, Liu Y, Li D, Qiu J, Chi M, Bi M, Zhang Q, Li Y, Motamedi Joibari M, Nilsson SK, Tan NS, Fan Y, Li L. Fan H, et al. Among authors: tan ns. Adv Sci (Weinh). 2026 Apr;13(23):e01909. doi: 10.1002/advs.202501909. Epub 2026 Mar 23. Adv Sci (Weinh). 2026. PMID: 41869866 Free PMC article.

190

Benralizumab reduces sputum ANCA in patients with eosinophilic granulomatosis with polyangiitis.

Mukherjee M, Tan NS, Huang C, Kim B, Radford K, Ju X, Venegas Garrido C, Kjarsgaard M, Rodríguez-Suárez E, Wechsler ME, Walker B, Börjesson Sjö L, Necander S, Ashkar A, Weidner J, Sehmi R, McCrae C, Khalidi N, Nair P. Mukherjee M, et al. Among authors: tan ns. ERJ Open Res. 2026 Mar 9;12(2):01134-2025. doi: 10.1183/23120541.01134-2025. eCollection 2026 Mar. ERJ Open Res. 2026. PMID: 41809856 Free PMC article.

191

Interrupting glioblastoma malignant circuitry: plasticity traps, synaptic blockade, and myeloid reprogramming.

Cheng HS, Tang C, Tan NS. Cheng HS, et al. Among authors: tan ns. Curr Opin Clin Nutr Metab Care. 2026 Jul 1;29(4):353-360. doi: 10.1097/MCO.0000000000001208. Epub 2026 Jan 8. Curr Opin Clin Nutr Metab Care. 2026. PMID: 41502293 Review.

192

A novel method to assess airway eosinophilia using sputum plugs.

Patel Z, Tan NS, Huynh A, Radford K, Calma N, Harper L, Somalwar S, Huang C, Kjarsgaard M, Ayoub A, Nair P, Mukherjee M. Patel Z, et al. Among authors: tan ns. ERJ Open Res. 2026 Jan 5;12(1):00604-2025. doi: 10.1183/23120541.00604-2025. eCollection 2026 Jan. ERJ Open Res. 2026. PMID: 41497329 Free PMC article.

193

A gut-liver lipid flux checkpoint mediates FAHFA protection from MASLD.

Xie H, Cheng HS, Ng JXJ, Zhang S, Kim JHS, Tan SH, Tan CH, Tan NS. Xie H, et al. Among authors: tan sh, tan ch, tan ns. Pharmacol Res. 2026 Feb;224:108085. doi: 10.1016/j.phrs.2025.108085. Epub 2026 Jan 2. Pharmacol Res. 2026. PMID: 41485679 Free article.

194

Relationship Between QRS Fragmentation on Electrocardiogram and Myocardial Scar Characterization on Cardiac Magnetic Resonance Imaging in Patients With Ischemic and Nonischemic Cardiomyopathy.

AlAnezi M, Barichello S, Nouraei H, Singh SM, Tan NS, Parmar VS, Dorian P, Chacko BR, Yan RT, Ge Y, Ahmad K, Shalmon T, Jimenez-Juan L, Deva DP, Yan AT. AlAnezi M, et al. Among authors: tan ns. Am J Cardiol. 2025 Dec 15;257:147-152. doi: 10.1016/j.amjcard.2025.09.053. Epub 2025 Oct 7. Am J Cardiol. 2025. PMID: 41061874

195

Transfer Learning-Assisted SERS: Predicting Molecular Identity and Concentration in Mixtures Using Pure Compound Spectra.

Tan EX, Chen JRT, Pang DWC, Tan NS, Phang IY, Ling XY. Tan EX, et al. Among authors: tan ns. Angew Chem Int Ed Engl. 2025 Sep 1;64(36):e202508717. doi: 10.1002/anie.202508717. Epub 2025 Jul 7. Angew Chem Int Ed Engl. 2025. PMID: 40601912

196

Respiratory burden in post-acute COVID-19 sequelae: a longitudinal study of airway and systemic inflammation and clinical outcomes.

Chiu MN, Chowdhury A, Zhang K, Somalwar S, Jamil R, Thakar A, Sidhom K, Sedhom N, Thanavala N, Mukherjee M, Kjarsgaard M, Venegas CG, Radadia N, Tan NS, Patel Z, Ahammed N, Isshiki T, Nolasco S, Chagla Z, Kolb M, Duong M, Gershon AS, Nair P, Satia I, Tselios K, Ho T, Balakrishnan N, Svenningsen S, Mukherjee M. Chiu MN, et al. Among authors: tan ns. ERJ Open Res. 2025 Jun 23;11(3):01331-2024. doi: 10.1183/23120541.01331-2024. eCollection 2025 May. ERJ Open Res. 2025. PMID: 40551795 Free PMC article.

197

Comprehensive analysis of multi-omics single-cell data using the single-cell analyst.

Pan L, Tang B, Zhang X, Parini P, Tremmel R, Loscalzo J, Lauschke VM, Maron BA, Paci P, Ernberg I, Tan NS, Végvári Á, Liao Z, Rengarajan S, Zubarev R, Fan Y, Zheng X, Jian X, Sheng R, Wang Z, Li X. Pan L, et al. Among authors: tan ns. Imeta. 2025 Apr 28;4(3):e70038. doi: 10.1002/imt2.70038. eCollection 2025 Jun. Imeta. 2025. PMID: 40469516 Free PMC article.

198

Sputum Cellularity and MRI Ventilation Defects in Severe Asthma.

Serajeddini H, Thakar A, Kjarsgaard M, Huang C, Ragunayakam N, Sandhu E, Venegas Garrido C, Friedlander Y, Konyer N, Zhang K, Tan NS, Radford K, Mukherjee M, Nair P, Svenningsen S. Serajeddini H, et al. Among authors: tan ns. Chest. 2025 Oct;168(4):860-873. doi: 10.1016/j.chest.2025.05.013. Epub 2025 May 20. Chest. 2025. PMID: 40404048 Free PMC article.

199

Cognitive benefits of hearing intervention vary by risk of cognitive decline: A secondary analysis of the ACHIEVE trial.

Pike JR, Huang AR, Reed NS, Arnold M, Chisolm T, Couper D, Deal JA, Glynn NW, Goman AM, Hayden KM, Mitchell CM, Pankow JS, Sanchez V, Sullivan KJ, Tan NS, Coresh J, Lin FR; ACHIEVE Collaborative Research Group. Pike JR, et al. Among authors: tan ns. Alzheimers Dement. 2025 May;21(5):e70156. doi: 10.1002/alz.70156. Alzheimers Dement. 2025. PMID: 40369891 Free PMC article. Clinical Trial.

200

Non-viral, high throughput genetic engineering of primary immune cells using nanostraw-mediated transfection.

Kumar ARK, Low J, Lim J, Myint B, Sun X, Wu L, Cheng HS, Yip S, Ming Cheng CZ, Manoharan T, Quek YJ, Shou Y, Tian JS, Ng YY, Gascoigne NRJ, Tan NS, Sugimura R, Chia G, Sze Cheung AM, Yawata M, Tay A. Kumar ARK, et al. Among authors: tan ns. Biomaterials. 2025 Jun;317:123079. doi: 10.1016/j.biomaterials.2024.123079. Epub 2025 Jan 5. Biomaterials. 2025. PMID: 39842078

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