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Depletion of Fibrinogen Suppresses Growth of Primary Tumors and Metastasis of Pancreatic Ductal Adenocarcinoma.
Chowdhury NN, Mitchell DK, Kangro K, Eldridge K, Abrahams S, Ferraresso F, Juang LJ, Gampala S, Brewster K, Revenko A, Kastrup C, Territo PR, Clapp DW, Wang J, Belgodere JA, Saeed O, Choi SR, Han B, Wolberg AS, Cao S, Zhang C, Flick MJ, Fishel ML. Chowdhury NN, et al. Gastroenterology. 2026 Apr;170(4):753-768. doi: 10.1053/j.gastro.2025.09.024. Epub 2025 Dec 23. Gastroenterology. 2026. PMID: 41432649 Free PMC article.
Medication Adherence in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE).
Gonzalez JS, Wen H, Butera NM, Uschner D, Krause-Steinrauf H, Gramzinski MR, Wexler DJ, Petrovitch H, Hoogendoorn CJ, Crespo-Ramos G, Presley C, Fattaleh B, Lagari V, Walker EA, Cherrington AL; GRADE Research Group*. Gonzalez JS, et al. Diabetes Care. 2026 Feb 1;49(2):335-343. doi: 10.2337/dc25-2008. Diabetes Care. 2026. PMID: 41557987 Free PMC article. Clinical Trial.
Dual CDK4/6-PI3K/mTOR inhibition reinforces cytostatic programs and tumor control in preclinical models of primary and metastatic osteosarcoma.
Barghi F, Saadatzadeh MR, Dobrota EA, Shannon HE, Bailey BJ, Young C, Malko R, Justice R, Riyahi N, Davis C, Bijangi-Vishehsaraei K, Kreklau K, Stevens LK, Koenig J, Sulayman S, Liu S, Wan J, Trowbridge MA, Coy K, Kennedy FM, Sinn AL, Just M, Jackson KW, Sandusky G, Wurtz LD, Collier CD, Mitchell D, Seiden EE, Greenfield EM, Doud E, Mosley A, Angus SP, Ferguson MJ, Pandya PH, Pollok KE. Barghi F, et al. Neoplasia. 2026 Feb;72:101266. doi: 10.1016/j.neo.2025.101266. Epub 2026 Jan 15. Neoplasia. 2026. PMID: 41544376 Free PMC article.
The Secretome of Human Trophoblast Stem Cells Attenuates Senescence-Associated Traits.
Abdelmohsen K, Martindale JL, Rossi M, Shin CH, Pal A, Munk R, Salamini-Montemurri M, Baranzini M, Arends EM, Mustapic M, Lee Y, Lee JN, Popma SH, Hu J, Duda N, Nogueras-Ortiz CJ, Kapogiannis D, Cui CY, Gorospe M. Abdelmohsen K, et al. Aging Cell. 2026 Feb;25(2):e70368. doi: 10.1111/acel.70368. Aging Cell. 2026. PMID: 41521531 Free PMC article.
Differential Longitudinal Effects of Glucose-Lowering Medications on Glucagon and C-peptide Responses in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE).
Kahn SE, Tripputi M, Lachin JM, Balasubramanyam A, Banerji MA, Barzilay J, Cohen RM, Garvey WT, Gramzinski MR, Rasouli N, Rhee M, Seegmiller JC, Singh V, Sivitz WI, Steffes MW, Utzschneider K, DeFronzo RA; GRADE Research Group*. Kahn SE, et al. Diabetes Care. 2026 Feb 1;49(2):325-334. doi: 10.2337/dc25-2186. Diabetes Care. 2026. PMID: 41432725 Free PMC article. Clinical Trial.
EXOSC3 G191 Variants Trigger System-Wide Recalibration of RNA Processing Machinery.
Wijeratne HRS, Runnebohm AM, Barron MP, Hampton AJ, Li R, Peck Justice SA, Lenceski SH, Rooney JD, Smith-Kinnaman WR, Chang GS, Doud EH, Kim J, Pelletier S, Liu Y, Vilseck JZ, Mosley AL. Wijeratne HRS, et al. bioRxiv [Preprint]. 2026 Jan 28:2026.01.26.701775. doi: 10.64898/2026.01.26.701775. bioRxiv. 2026. PMID: 41659589 Free PMC article. Preprint.
International norms for adult handgrip strength: A systematic review of data on 2.4 million adults aged 20 to 100+ years from 69 countries and regions.
Tomkinson GR, Lang JJ, Rubín L, McGrath R, Gower B, Boyle T, Klug MG, Mayhew AJ, Blake HT, Ortega FB, Cadenas-Sanchez C, Magnussen CG, Fraser BJ, Kidokoro T, Liu Y, Christensen K, Leong DP; iGRIPS (international handGRIP Strength) Group. Tomkinson GR, et al. J Sport Health Sci. 2025 Dec;14:101014. doi: 10.1016/j.jshs.2024.101014. Epub 2024 Dec 6. J Sport Health Sci. 2025. PMID: 39647778 Free PMC article.
Differences in Prevalence and Incidence of Electrocardiogram Abnormalities and Cardiovascular Autonomic Neuropathy Among Randomized Glucose-Lowering Treatments in Early Type 2 Diabetes: The Glycemia Reduction Approaches in Diabetes (GRADE) Cohort.
Pop-Busui R, Rosin SP, Butera NM, Krause-Steinrauf H, Abou Assi H, Garg RK, Inzucchi SE, Katona A, McGill JB, Mudaliar S, Schade DS, Seaquist ER, Tiktin M, Soliman EZ, Green JB; GRADE Research Group. Pop-Busui R, et al. Diabetes Care. 2025 Nov 1;48(11):1960-1970. doi: 10.2337/dc25-1087. Diabetes Care. 2025. PMID: 40986645 Free PMC article. Clinical Trial.
Common genetic variants near SLC2A2 and glycemic response to glimepiride in the GRADE comparative effectiveness clinical trial.
Li JH, Szczerbinski L, Tripputi M, Liu H, Nam S, Mujica E, Emmanouilidou A, Wangden TY, Citko-Rojewska A, Konopka P, Czajkowski M, Huerta-Chagoya A, Vora M, Leong A, Meigs JB, Ng MY, Loos RJF, Pigeyre M, Gerstein HC, Moura FA, Lai YP, Bhatt DL, Marston NA, Ruff CT, Sabatine MS, Dawed AY, Pearson ER, Satin LS, den Hoed M, Kretowski A, Kahn SE, Younes N, Mercader JM, Florez JC. Li JH, et al. medRxiv [Preprint]. 2025 Oct 8:2025.10.07.25336827. doi: 10.1101/2025.10.07.25336827. medRxiv. 2025. PMID: 41282760 Free PMC article. Preprint.
Germline Variants Influence Chronic Liver Disease Progression through Distinct Pathways.
Vujkovic M, Kaplan DE, Ghouse J, Loza BL, Brancale J, Lewis A, Zhang DY, Levin MG, Veatch OJ, Johnson JP, Schneider CV, Verma A, Wangensteen KJ, Scorletti E, Gill D, Konkwo C, Garófalo AM, Guare LA, Schwantes-An TW, Abreu MV, Gellert-Kristensen H, Pedersen OB, Erikstrup C, Bundgaard JS, Sørensen E, Ostrowski SR, Bundgaard H, Lee KM, Shaked A, Olthoff KM, Hoteit MA, Speliotes EK, Chen Y, Oliveri A, Yin L, Valenti LV, Malvestiti F, Marchelli D, Miano L, Anstee QM, Daly AK, Cordell HJ, Darlay R, Verweij N, Hindy G, Locke A, Matsuura K, Asrani SK, Testa G, Lotta LA, Jones MB, Dochtermann DR, Norden-Krichmar TM, Teerlink CC, Devineni P, Pyarajan S, Rader DJ, Tanaka Y, Voight BF, Vilarinho S, Bastarache LA, Stender S, Tsao PS; Penn Medicine Biobank; DBDS Genomic Consortium; BioVU Biobank; Michigan Genomics Initiative; Regeneron Genetics Center; Indiana Biobank; All Of Us Research Program; Milano Biobank; LITMUS Consortium; VA Million Veteran Program; Morgan TR, Lynch JA, Chang KM. Vujkovic M, et al. medRxiv [Preprint]. 2025 Sep 18:2025.09.16.25335186. doi: 10.1101/2025.09.16.25335186. medRxiv. 2025. PMID: 41001506 Free PMC article. Preprint.
Impact Induces Phagocytic Defect in Reactive Microglia.
Yu R, Rogers EA, Manchanda P, Beveridge CH, Randolph CE, Beauclair TB, Jethava KP, Shi R, Chopra G. Yu R, et al. bioRxiv [Preprint]. 2025 Sep 17:2025.09.14.676171. doi: 10.1101/2025.09.14.676171. bioRxiv. 2025. PMID: 41000981 Free PMC article. Preprint.
Effect of Paxlovid treatment during acute COVID-19 on Long COVID onset: An EHR-based target trial emulation from the N3C and RECOVER consortia.
Preiss A, Bhatia A, Aragon LV, Baratta JM, Baskaran M, Blancero F, Brannock MD, Chew RF, Díaz I, Fitzgerald M, Kelly EP, Zhou AG, Carton TW, Chute CG, Haendel M, Moffitt R, Pfaff E; N3C Consortium and the RECOVER Cohort. Preiss A, et al. PLoS Med. 2025 Sep 15;22(9):e1004711. doi: 10.1371/journal.pmed.1004711. eCollection 2025 Sep. PLoS Med. 2025. PMID: 40953059 Free PMC article.
Re-engineering a machine learning phenotype to adapt to the changing COVID-19 landscape: a machine learning modelling study from the N3C and RECOVER consortia.
Crosskey M, McIntee T, Preiss S, Brannock D, Baratta JM, Yoo YJ, Hadley E, Blanceró F, Chew R, Loomba J, Bhatia A, Chute CG, Haendel M, Moffitt R, Pfaff ER; N3C Consortium and the RECOVER EHR cohort. Crosskey M, et al. Lancet Digit Health. 2025 Aug;7(8):100887. doi: 10.1016/j.landig.2025.100887. Epub 2025 Aug 25. Lancet Digit Health. 2025. PMID: 40858480 Free PMC article.
Lack of Association of Emotional Distress With Insulin Initiation in the GRADE Randomized Diabetes Comparative Effectiveness Trial.
Presley CA, Butera NM, Krause-Steinrauf H, Desouza CV, Hollander PA, Hoogendoorn CJ, Lagari VS, Legowski EA, Martin CL, Rasouli N, Gonzalez JS, Cherrington AL. Presley CA, et al. Sci Diabetes Self Manag Care. 2025 Aug;51(4):382-393. doi: 10.1177/26350106251361363. Epub 2025 Aug 1. Sci Diabetes Self Manag Care. 2025. PMID: 40751289 Clinical Trial.
Identifying People Living With or Those at Risk for HIV in a Nationally Sampled Electronic Health Record Repository Called the National Clinical Cohort Collaborative: Computational Phenotyping Study.
Hurwitz E, Varley CD, Anzolone AJ, Madhira V, Olex AL, Sun J, Vaidya D, Fadul N, Islam JY, Jackson LE, Wilkins KJ, Butzin-Dozier Z, Li D, Safo SE, McMurry JA, Maheria P, Williams T, Hassan SA, Haendel MA, Patel RC; National Clinical Cohort Collaborative (N3C) Consortium. Hurwitz E, et al. JMIR Med Inform. 2025 Jul 11;13:e68143. doi: 10.2196/68143. JMIR Med Inform. 2025. PMID: 40644699 Free PMC article.
Association of Hospitalizations With Randomized Glycemia-Lowering Treatment in GRADE.
Hsia DS, Younes N, Ghosh A, Kazemi EJ, Krause-Steinrauf H, Buse JB, Baker C, Brown-Friday J, Diaz E, Diner J, Groessl EJ, Legowski EA, Mariash CN, Waltje AH, Wexler DJ, Martin CL; GRADE Research Group. Hsia DS, et al. Diabetes Care. 2025 Jul 1;48(7):1288-1294. doi: 10.2337/dc24-2839. Diabetes Care. 2025. PMID: 40424051 Free PMC article. Clinical Trial.
VDAC1 is a target for pharmacologically induced insulin hypersecretion in β cells.
Roy G, Ordóñez A, Binns DD, Rodrigues-Dos-Santos K, Kwakye MB, King GC, Kuntz RL, Mukherjee N, Templin AT, Tan Z, Richardson TI, Doud EH, Mosley AL, Schueler KL, Emfinger CH, Attie AD, Keller MP, Johnson TS, Kalwat MA. Roy G, et al. Cell Rep. 2025 Jun 24;44(6):115834. doi: 10.1016/j.celrep.2025.115834. Epub 2025 Jun 11. Cell Rep. 2025. PMID: 40512624 Free PMC article.
Alternative splicing of uromodulin enhances mitochondrial metabolism for adaptation to stress in kidney epithelial cells.
Nanamatsu A, Rhodes GJ, LaFavers KA, Micanovic R, Lazar V, Khan S, Barwinska D, Makino S, Zollman A, Cheng YH, Doud EH, Mosley AL, Repass MJ, Kamocka MM, Baride A, Phillips CL, Kelly KJ, Eadon MT, Himmelfarb J, Kretzler M, Bacallao RL, Dagher PC, Hato T, El-Achkar TM. Nanamatsu A, et al. J Clin Invest. 2025 Apr 8;135(12):e183343. doi: 10.1172/JCI183343. eCollection 2025 Jun 16. J Clin Invest. 2025. PMID: 40198127 Free PMC article.
Amyloid-β induces lipid droplet-mediated microglial dysfunction via the enzyme DGAT2 in Alzheimer's disease.
Prakash P, Manchanda P, Paouri E, Bisht K, Sharma K, Rajpoot J, Wendt V, Hossain A, Wijewardhane PR, Randolph CE, Chen Y, Stanko S, Gasmi N, Gjojdeshi A, Card S, Fine J, Jethava KP, Clark MG, Dong B, Ma S, Crockett A, Thayer EA, Nicolas M, Davis R, Hardikar D, Allende D, Prayson RA, Zhang C, Davalos D, Chopra G. Prakash P, et al. Immunity. 2025 Jun 10;58(6):1536-1552.e8. doi: 10.1016/j.immuni.2025.04.029. Epub 2025 May 19. Immunity. 2025. PMID: 40393454 Free PMC article.
Gene therapies alleviate absence epilepsy associated with Scn2a deficiency in DBA/2J mice.
Zhang Z, Zhang J, Chen X, Deming BA, Kant S, Mandal P, Kothandaraman H, SanMiguel PJ, Halurkar MS, Abeyaratna AD, Robinson MJ, Zhao Y, Vitko Y, Gaykema RP, Yuan C, Lanman NA, Tegtmeyer MT, Wang D, Gao G, Shi R, Perez-Reyes E, Yang Y. Zhang Z, et al. bioRxiv [Preprint]. 2025 Jun 6:2025.06.03.657652. doi: 10.1101/2025.06.03.657652. bioRxiv. 2025. PMID: 40501831 Free PMC article. Preprint.
EXOSC3 S1-domain variants implicated in PCH1b alter RNA exosome cap subunit abundance and thermal stability disrupting rRNA processing and targeting of AU-rich mRNA.
Runnebohm AM, Wijeratne HRS, Barron MP, Smith-Kinnaman WR, Rooney JD, Peck Justice SA, Cureton LA, Holland A, Ghalei H, Pelletier S, Doud EH, Vilseck JZ, Mosley AL. Runnebohm AM, et al. bioRxiv [Preprint]. 2025 Jun 1:2025.05.31.657176. doi: 10.1101/2025.05.31.657176. bioRxiv. 2025. PMID: 40501579 Free PMC article. Preprint.
Weight Gain Was Associated With Worsening Glycemia and Cardiovascular and Kidney Outcomes in Patients With Type 2 Diabetes Independent of Diabetes Medication in the GRADE Randomized Controlled Trial.
Wexler DJ, Garvey WT, Ghosh A, Kazemi EJ, Krause-Steinrauf H, Ahmann AJ, Brown-Friday J, Casula S, Cherrington AL, Elasy TA, Fortmann SP, Krakoff JA, Mudaliar S, Tiktin M, Younes N; GRADE Study Research Group. Wexler DJ, et al. Diabetes Care. 2025 Jun 1;48(6):935-944. doi: 10.2337/dc24-2825. Diabetes Care. 2025. PMID: 40267365 Free PMC article. Clinical Trial.
Association of COVID-19 With Risk of Posttransplant Diabetes Mellitus.
Vinson AJ, Anzalone AJ, Schissel M, Dai R, Olex AL, Mannon RB; on behalf of the National COVID Cohort Collaborative. Vinson AJ, et al. Transplantation. 2025 May 1;109(5):e253-e261. doi: 10.1097/TP.0000000000005227. Epub 2024 Nov 6. Transplantation. 2025. PMID: 39531312 Free PMC article.
EFFECT OF PAXLOVID TREATMENT DURING ACUTE COVID-19 ON LONG COVID ONSET: AN EHR-BASED TARGET TRIAL EMULATION FROM THE N3C AND RECOVER CONSORTIA.
Preiss A, Bhatia A, Aragon LV, Baratta JM, Baskaran M, Blancero F, Brannock MD, Chew RF, Díaz I, Fitzgerald M, Kelly EP, Zhou A, Carton TW, Chute CG, Haendel M, Moffitt R, Pfaff E. Preiss A, et al. medRxiv [Preprint]. 2025 Apr 7:2024.01.20.24301525. doi: 10.1101/2024.01.20.24301525. medRxiv. 2025. Update in: PLoS Med. 2025 Sep 15;22(9):e1004711. doi: 10.1371/journal.pmed.1004711. PMID: 38343863 Free PMC article. Updated. Preprint.
Long COVID after SARS-CoV-2 during pregnancy in the United States.
Zang C, Guth D, Bruno AM, Xu Z, Li H, Ammar N, Chew R, Guthe N, Hadley E, Kaushal R, Love T, McGrath BM, Patel RC, Seibert EC, Senathirajah Y, Singh SK, Wang F, Weiner MG, Wilkins KJ, Zhang Y, Metz TD, Hill E, Carton TW; RECOVER PCORnet EHR Consortia; RECOVER N3C EHR Consortia; RECOVER Pregnancy Consortia. Zang C, et al. Nat Commun. 2025 Apr 1;16(1):3005. doi: 10.1038/s41467-025-57849-9. Nat Commun. 2025. PMID: 40169569 Free PMC article.
Differential Treatment Effects on β-Cell Function Using Model-Based Parameters in Type 2 Diabetes: Results From the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE).
Utzschneider KM, Tripputi M, Butera NM, Mari A, Rosin SP, Banerji MA, Bergenstal RM, Brown N, Carlson AL, DeFronzo RA, Gramzinski MR, Harindhanavudhi T, Kozedub A, Sivitz WI, Steffes MW, Balasubramanyam A, Rasouli N; GRADE Research Group. Utzschneider KM, et al. Diabetes Care. 2025 Apr 1;48(4):623-631. doi: 10.2337/dc24-2419. Diabetes Care. 2025. PMID: 39998948 Free PMC article. Clinical Trial.
Feasibility and acceptability of a telephone-based ACT intervention for caregivers (TACTICs) of adults with Alzheimer's disease and related dementias (ADRD): a randomized pilot during the COVID-19 pandemic.
Hockemeyer NG, Johns SA, Judge KS, Baucco C, Gowan T, Slaven JE, Fowler NR. Hockemeyer NG, et al. Aging Ment Health. 2025 Apr;29(4):639-650. doi: 10.1080/13607863.2025.2453823. Epub 2025 Jan 21. Aging Ment Health. 2025. PMID: 39838852 Free PMC article. Clinical Trial.
Restoration of excitation/inhibition balance enhances neuronal signal-to-noise ratio and rescues social deficits in autism-associated Scn2a-deficiency.
Zhang J, Eaton M, Chen X, Zhao Y, Kant S, Deming BA, Harish K, Nguyen HP, Shu Y, Lai S, Wu J, Que Z, Wettschurack KW, Zhang Z, Xiao T, Halurkar MS, Olivero-Acosta MI, Yoo YE, Lanman NA, Koss WA, Skarnes WC, Yang Y. Zhang J, et al. bioRxiv [Preprint]. 2025 Mar 5:2025.03.04.641498. doi: 10.1101/2025.03.04.641498. bioRxiv. 2025. PMID: 40093153 Free PMC article. Preprint.
Lipids: Emerging Players of Microglial Biology.
Prakash P, Randolph CE, Walker KA, Chopra G. Prakash P, et al. Glia. 2025 Mar;73(3):657-677. doi: 10.1002/glia.24654. Epub 2024 Dec 17. Glia. 2025. PMID: 39688320 Free PMC article. Review.
Effect of nirmatrelvir/ritonavir (Paxlovid) on hospitalization among adults with COVID-19: An electronic health record-based target trial emulation from N3C.
Bhatia A, Preiss AJ, Xiao X, Brannock MD, Alexander GC, Chew RF, Davis H, Fitzgerald M, Hill E, Kelly EP, Mehta HB, Madlock-Brown C, Wilkins KJ, Chute CG, Haendel M, Moffitt R, Pfaff ER; N3C Consortium. Bhatia A, et al. PLoS Med. 2025 Jan 17;22(1):e1004493. doi: 10.1371/journal.pmed.1004493. eCollection 2025 Jan. PLoS Med. 2025. PMID: 39823513 Free PMC article.
Utilization of Cannabidiol in Post-Organ-Transplant Care.
Koyama S, Etkins J, Jun J, Miller M, So GC, Gisch DL, Eadon MT. Koyama S, et al. Int J Mol Sci. 2025 Jan 15;26(2):699. doi: 10.3390/ijms26020699. Int J Mol Sci. 2025. PMID: 39859413 Free PMC article. Review.
Human IPSC-Derived Microglia Sense and Dampen Hyperexcitability of Cortical Neurons Carrying the Epilepsy-Associated SCN2A-L1342P Mutation.
Que Z, Olivero-Acosta MI, Robinson M, Chen I, Zhang J, Wettschurack K, Wu J, Xiao T, Otterbacher CM, Shankar V, Harlow H, Hong S, Zirkle B, Wang M, Cui N, Mandal P, Chen X, Deming B, Halurkar M, Zhao Y, Rochet JC, Xu R, Brewster AL, Wu LJ, Yuan C, Skarnes WC, Yang Y. Que Z, et al. J Neurosci. 2025 Jan 15;45(3):e2027232024. doi: 10.1523/JNEUROSCI.2027-23.2024. J Neurosci. 2025. PMID: 39557580 Free PMC article.
miRNA and mRNA Signatures in Human Acute Kidney Injury Tissue.
Janosevic D, De Luca T, Melo Ferreira R, Gisch DL, Cheng YH, Hato T, Luo J, Yang Y, Hodgin JB, Phillips CL, Dagher PC; Kidney Precision Medicine Project; Eadon MT. Janosevic D, et al. Am J Pathol. 2025 Jan;195(1):102-114. doi: 10.1016/j.ajpath.2024.08.013. Epub 2024 Sep 25. Am J Pathol. 2025. PMID: 39332675 Free PMC article.
Long-Term Mortality Following SARS-CoV-2 Infection in Rural Versus Urban Dwellers With Autoimmune or Inflammatory Rheumatic Disease: A Retrospective Cohort Analysis From the National COVID Cohort Collaborative.
Anzalone AJ, Jackson LE, Singh N, Danila MI, Reisher E, Patel RC, Singh JA; National COVID Cohort Collaborative Consortium. Anzalone AJ, et al. Arthritis Care Res (Hoboken). 2025 Jan;77(1):143-155. doi: 10.1002/acr.25421. Epub 2024 Oct 16. Arthritis Care Res (Hoboken). 2025. PMID: 39158165 Free PMC article.
Amyloid β Induces Lipid Droplet-Mediated Microglial Dysfunction in Alzheimer's Disease.
Prakash P, Manchanda P, Paouri E, Bisht K, Sharma K, Rajpoot J, Wendt V, Hossain A, Wijewardhane PR, Randolph CE, Chen Y, Stanko S, Gasmi N, Gjojdeshi A, Card S, Fine J, Jethava KP, Clark MG, Dong B, Ma S, Crockett A, Thayer EA, Nicolas M, Davis R, Hardikar D, Allende D, Prayson RA, Zhang C, Davalos D, Chopra G. Prakash P, et al. bioRxiv [Preprint]. 2024 Dec 4:2023.06.04.543525. doi: 10.1101/2023.06.04.543525. bioRxiv. 2024. Update in: Immunity. 2025 Jun 10;58(6):1536-1552.e8. doi: 10.1016/j.immuni.2025.04.029. PMID: 37333071 Free PMC article. Updated. Preprint.
Relationship Between Average Glucose Levels and HbA1c Differs Across Racial Groups: A Substudy of the GRADE Randomized Trial.
Nathan DM, Herman WH, Larkin ME, Krause-Steinrauf H, Abou Assi H, Ahmann AJ, Brown-Friday J, Hsia DS, Harindhanavudhi T, Johnson M, Arends VL, Butera NM, Rosin SP, Lachin JM, Younes N; GRADE Study Research Group. Nathan DM, et al. Diabetes Care. 2024 Dec 1;47(12):2155-2163. doi: 10.2337/dc24-1362. Diabetes Care. 2024. PMID: 39312277 Free PMC article. Clinical Trial.
Glycemia reduction in type 2 diabetes-Hypoglycemia outcomes: A randomized clinical trial.
Seaquist ER, Phillips LS, Ghosh A, Baker C, Bergenstal RM, Crandall JP, Goland RS, Gramzinski MR, Hox SH, Hsia DS, Johnson ML, Lachin JM, Raskin P, Valencia WM, Waltje AH, Younes N; GRADE Research Group. Seaquist ER, et al. PLoS One. 2024 Nov 15;19(11):e0309907. doi: 10.1371/journal.pone.0309907. eCollection 2024. PLoS One. 2024. PMID: 39546502 Free PMC article. Clinical Trial.
Finding Long-COVID: temporal topic modeling of electronic health records from the N3C and RECOVER programs.
O'Neil ST, Madlock-Brown C, Wilkins KJ, McGrath BM, Davis HE, Assaf GS, Wei H, Zareie P, French ET, Loomba J, McMurry JA, Zhou A, Chute CG, Moffitt RA, Pfaff ER, Yoo YJ, Leese P, Chew RF, Lieberman M, Haendel MA; N3C and RECOVER Consortia. O'Neil ST, et al. NPJ Digit Med. 2024 Oct 21;7(1):296. doi: 10.1038/s41746-024-01286-3. NPJ Digit Med. 2024. PMID: 39433942 Free PMC article.
Acquisition of neurodegenerative features in isogenic OPTN(E50K) human stem cell-derived retinal ganglion cells associated with autophagy disruption and mTORC1 signaling reduction.
Huang KC, Gomes C, Shiga Y, Belforte N, VanderWall KB, Lavekar SS, Fligor CM, Harkin J, Hetzer SM, Patil SV, Di Polo A, Meyer JS. Huang KC, et al. Acta Neuropathol Commun. 2024 Oct 18;12(1):164. doi: 10.1186/s40478-024-01872-2. Acta Neuropathol Commun. 2024. PMID: 39425218 Free PMC article.
SSRI use during acute COVID-19 and risk of long COVID among patients with depression.
Butzin-Dozier Z, Ji Y, Deshpande S, Hurwitz E, Anzalone AJ, Coyle J, Shi J, Mertens A, van der Laan MJ, Colford JM Jr, Patel RC, Hubbard AE; National COVID Cohort Collaborative (N3C) Consortium. Butzin-Dozier Z, et al. BMC Med. 2024 Oct 8;22(1):445. doi: 10.1186/s12916-024-03655-x. BMC Med. 2024. PMID: 39380062 Free PMC article.
Cardiovascular disease in thymic cancer patients.
Khemka A, Clasen SC, Loehrer PJ, Roberts AR, Golzarri-Arroyo L, Badve SS, Raman SV, Hui SL, Schleyer TKL. Khemka A, et al. Front Cardiovasc Med. 2024 Sep 10;11:1393631. doi: 10.3389/fcvm.2024.1393631. eCollection 2024. Front Cardiovasc Med. 2024. PMID: 39346095 Free PMC article.
Agonist antibody to guanylate cyclase receptor NPR1 regulates vascular tone.
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