Wahli W - Search Results

1

Angptl4 integrates dietary and microbial signals to disrupt gut barrier function in MASH.

Chua D, Low ZS, Kim JHS, Lee YH, Kiatbumrung R, Somnark P, Xu M, Shi Y, Kaushal G, Vos MIG, Mahadevan A, Hooi N, Raj M, Sviriaeva E, Cui B, Tan S, Kasahara K, Ho CL, Wahli W, Yew KC, Wong SH, Cheung C, Pal M, Zhang R, Chuaypen N, Tangkijvanich P, Cheng HS, Li L, Tan NS. Chua D, et al. Among authors: wahli w. Nat Commun. 2026 May 22. doi: 10.1038/s41467-026-72575-6. Online ahead of print. Nat Commun. 2026. PMID: 42173835 Free article.

2

Insights into the Role of PPARβ/δ in NAFLD.

Chen J, Montagner A, Tan NS, Wahli W. Chen J, et al. Among authors: wahli w. Int J Mol Sci. 2018 Jun 27;19(7):1893. doi: 10.3390/ijms19071893. Int J Mol Sci. 2018. PMID: 29954129 Free PMC article. Review.

3

Exploiting vulnerabilities of cancer by targeting nuclear receptors of stromal cells in tumor microenvironment.

Cheng HS, Lee JXT, Wahli W, Tan NS. Cheng HS, et al. Among authors: wahli w. Mol Cancer. 2019 Mar 30;18(1):51. doi: 10.1186/s12943-019-0971-9. Mol Cancer. 2019. PMID: 30925918 Free PMC article. Review.

4

Deficiency in fibroblast PPARβ/δ reduces nonmelanoma skin cancers in mice.

Tan MWY, Sng MK, Cheng HS, Low ZS, Leong BJJ, Chua D, Tan EHP, Chan JSK, Yip YS, Lee YH, Pal M, Wang X, Wahli W, Tan NS. Tan MWY, et al. Among authors: wahli w. Cell Death Differ. 2020 Sep;27(9):2668-2680. doi: 10.1038/s41418-020-0535-y. Epub 2020 Apr 20. Cell Death Differ. 2020. PMID: 32313198 Free PMC article.

5

PPARs and Tumor Microenvironment: The Emerging Roles of the Metabolic Master Regulators in Tumor Stromal-Epithelial Crosstalk and Carcinogenesis.

Cheng HS, Yip YS, Lim EKY, Wahli W, Tan NS. Cheng HS, et al. Among authors: wahli w. Cancers (Basel). 2021 Apr 29;13(9):2153. doi: 10.3390/cancers13092153. Cancers (Basel). 2021. PMID: 33946986 Free PMC article. Review.

6

The emerging role of Nrf2 in dermatotoxicology.

Tan NS, Wahli W. Tan NS, et al. Among authors: wahli w. EMBO Mol Med. 2014 Apr;6(4):431-3. doi: 10.1002/emmm.201303797. Epub 2014 Feb 12. EMBO Mol Med. 2014. PMID: 24521743 Free PMC article.

7

Studying Wound Repair in the Mouse.

Tan NS, Wahli W. Tan NS, et al. Among authors: wahli w. Curr Protoc Mouse Biol. 2013 Oct 18;3(3):171-85. doi: 10.1002/9780470942390.mo130135. Curr Protoc Mouse Biol. 2013. PMID: 26069050

8

Depletion of Gram-Positive Bacteria Impacts Hepatic Biological Functions During the Light Phase.

Oh HYP, Ellero-Simatos S, Manickam R, Tan NS, Guillou H, Wahli W. Oh HYP, et al. Among authors: wahli w. Int J Mol Sci. 2019 Feb 14;20(4):812. doi: 10.3390/ijms20040812. Int J Mol Sci. 2019. PMID: 30769793 Free PMC article.

9

The Potential of the FSP1cre-Pparb/d^-^/^- Mouse Model for Studying Juvenile NAFLD.

Chen J, Zhuang Y, Sng MK, Tan NS, Wahli W. Chen J, et al. Among authors: wahli w. Int J Mol Sci. 2019 Oct 15;20(20):5115. doi: 10.3390/ijms20205115. Int J Mol Sci. 2019. PMID: 31618976 Free PMC article.

10

PPARβ/δ Agonism Upregulates Forkhead Box A2 to Reduce Inflammation in C2C12 Myoblasts and in Skeletal Muscle.

Phua WWT, Tan WR, Yip YS, Hew ID, Wee JWK, Cheng HS, Leow MKS, Wahli W, Tan NS. Phua WWT, et al. Among authors: wahli w. Int J Mol Sci. 2020 Mar 4;21(5):1747. doi: 10.3390/ijms21051747. Int J Mol Sci. 2020. PMID: 32143325 Free PMC article.

11

Peroxisome proliferator-activated receptor-beta as a target for wound healing drugs.

Tan NS, Michalik L, Desvergne B, Wahli W. Tan NS, et al. Among authors: wahli w. Expert Opin Ther Targets. 2004 Feb;8(1):39-48. doi: 10.1517/14728222.8.1.39. Expert Opin Ther Targets. 2004. PMID: 14996617 Review.

12

Peroxisome proliferator-activated receptor (PPAR)-beta as a target for wound healing drugs: what is possible?

Tan NS, Michalik L, Desvergne B, Wahli W. Tan NS, et al. Among authors: wahli w. Am J Clin Dermatol. 2003;4(8):523-30. doi: 10.2165/00128071-200304080-00001. Am J Clin Dermatol. 2003. PMID: 12862494 Review.

13

Genetic- or transforming growth factor-beta 1-induced changes in epidermal peroxisome proliferator-activated receptor beta/delta expression dictate wound repair kinetics.

Tan NS, Michalik L, Desvergne B, Wahli W. Tan NS, et al. Among authors: wahli w. J Biol Chem. 2005 May 6;280(18):18163-70. doi: 10.1074/jbc.M412829200. Epub 2005 Feb 11. J Biol Chem. 2005. PMID: 15708854 Free article.

14

Multiple expression control mechanisms of peroxisome proliferator-activated receptors and their target genes.

Tan NS, Michalik L, Desvergne B, Wahli W. Tan NS, et al. Among authors: wahli w. J Steroid Biochem Mol Biol. 2005 Feb;93(2-5):99-105. doi: 10.1016/j.jsbmb.2004.12.025. J Steroid Biochem Mol Biol. 2005. PMID: 15860251 Review.

15

Smad3 deficiency in mice protects against insulin resistance and obesity induced by a high-fat diet.

Tan CK, Leuenberger N, Tan MJ, Yan YW, Chen Y, Kambadur R, Wahli W, Tan NS. Tan CK, et al. Among authors: wahli w. Diabetes. 2011 Feb;60(2):464-76. doi: 10.2337/db10-0801. Diabetes. 2011. PMID: 21270259 Free PMC article.

16

Roles of Estrogens in the Healthy and Diseased Oviparous Vertebrate Liver.

Tramunt B, Montagner A, Tan NS, Gourdy P, Rémignon H, Wahli W. Tramunt B, et al. Among authors: wahli w. Metabolites. 2021 Jul 30;11(8):502. doi: 10.3390/metabo11080502. Metabolites. 2021. PMID: 34436443 Free PMC article. Review.

17

ROS release by PPARβ/δ-null fibroblasts reduces tumor load through epithelial antioxidant response.

Tan EHP, Sng MK, How ISB, Chan JSK, Chen J, Tan CK, Wahli W, Tan NS. Tan EHP, et al. Among authors: wahli w. Oncogene. 2018 Apr;37(15):2067-2078. doi: 10.1038/s41388-017-0109-8. Epub 2018 Jan 25. Oncogene. 2018. PMID: 29367760 Free PMC article.

18

Transcriptional control of physiological and pathological processes by the nuclear receptor PPARβ/δ.

Tan NS, Vázquez-Carrera M, Montagner A, Sng MK, Guillou H, Wahli W. Tan NS, et al. Among authors: wahli w. Prog Lipid Res. 2016 Oct;64:98-122. doi: 10.1016/j.plipres.2016.09.001. Epub 2016 Sep 22. Prog Lipid Res. 2016. PMID: 27665713 Review. No abstract available.

19

Essential role of Smad3 in the inhibition of inflammation-induced PPARbeta/delta expression.

Tan NS, Michalik L, Di-Poï N, Ng CY, Mermod N, Roberts AB, Desvergne B, Wahli W. Tan NS, et al. Among authors: wahli w. EMBO J. 2004 Oct 27;23(21):4211-21. doi: 10.1038/sj.emboj.7600437. Epub 2004 Oct 7. EMBO J. 2004. PMID: 15470497 Free PMC article.

20

Antiapoptotic role of PPARbeta in keratinocytes via transcriptional control of the Akt1 signaling pathway.

Di-Poï N, Tan NS, Michalik L, Wahli W, Desvergne B. Di-Poï N, et al. Among authors: wahli w. Mol Cell. 2002 Oct;10(4):721-33. doi: 10.1016/s1097-2765(02)00646-9. Mol Cell. 2002. PMID: 12419217 Free article.

21

Epithelium-mesenchyme interactions control the activity of peroxisome proliferator-activated receptor beta/delta during hair follicle development.

Di-Poï N, Ng CY, Tan NS, Yang Z, Hemmings BA, Desvergne B, Michalik L, Wahli W. Di-Poï N, et al. Among authors: wahli w. Mol Cell Biol. 2005 Mar;25(5):1696-712. doi: 10.1128/MCB.25.5.1696-1712.2005. Mol Cell Biol. 2005. PMID: 15713628 Free PMC article.

22

The nuclear hormone receptor peroxisome proliferator-activated receptor beta/delta potentiates cell chemotactism, polarization, and migration.

Tan NS, Icre G, Montagner A, Bordier-ten-Heggeler B, Wahli W, Michalik L. Tan NS, et al. Among authors: wahli w. Mol Cell Biol. 2007 Oct;27(20):7161-75. doi: 10.1128/MCB.00436-07. Epub 2007 Aug 6. Mol Cell Biol. 2007. PMID: 17682064 Free PMC article.

23

Promoter rearrangements cause species-specific hepatic regulation of the glyoxylate reductase/hydroxypyruvate reductase gene by the peroxisome proliferator-activated receptor alpha.

Genolet R, Kersten S, Braissant O, Mandard S, Tan NS, Bucher P, Desvergne B, Michalik L, Wahli W. Genolet R, et al. Among authors: wahli w. J Biol Chem. 2005 Jun 24;280(25):24143-52. doi: 10.1074/jbc.M502649200. Epub 2005 Apr 19. J Biol Chem. 2005. PMID: 15840574 Free article.

24

Regulation of epithelial-mesenchymal IL-1 signaling by PPARbeta/delta is essential for skin homeostasis and wound healing.

Chong HC, Tan MJ, Philippe V, Tan SH, Tan CK, Ku CW, Goh YY, Wahli W, Michalik L, Tan NS. Chong HC, et al. Among authors: wahli w. J Cell Biol. 2009 Mar 23;184(6):817-31. doi: 10.1083/jcb.200809028. J Cell Biol. 2009. PMID: 19307598 Free PMC article.

25

The anti-apoptotic role of PPARbeta contributes to efficient skin wound healing.

Di-Poï N, Michalik L, Tan NS, Desvergne B, Wahli W. Di-Poï N, et al. Among authors: wahli w. J Steroid Biochem Mol Biol. 2003 Jun;85(2-5):257-65. doi: 10.1016/s0960-0760(03)00215-2. J Steroid Biochem Mol Biol. 2003. PMID: 12943711

26

Differentiation of trophoblast giant cells and their metabolic functions are dependent on peroxisome proliferator-activated receptor beta/delta.

Nadra K, Anghel SI, Joye E, Tan NS, Basu-Modak S, Trono D, Wahli W, Desvergne B. Nadra K, et al. Among authors: wahli w. Mol Cell Biol. 2006 Apr;26(8):3266-81. doi: 10.1128/MCB.26.8.3266-3281.2006. Mol Cell Biol. 2006. PMID: 16581799 Free PMC article.

27

Smad3 signaling is required for satellite cell function and myogenic differentiation of myoblasts.

Ge X, McFarlane C, Vajjala A, Lokireddy S, Ng ZH, Tan CK, Tan NS, Wahli W, Sharma M, Kambadur R. Ge X, et al. Among authors: wahli w. Cell Res. 2011 Nov;21(11):1591-604. doi: 10.1038/cr.2011.72. Epub 2011 Apr 19. Cell Res. 2011. PMID: 21502976 Free PMC article.

28

Selective deletion of PPARβ/δ in fibroblasts causes dermal fibrosis by attenuated LRG1 expression.

Sng MK, Chan JSK, Teo Z, Phua T, Tan EHP, Wee JWK, Koh NJN, Tan CK, Chen JP, Pal M, Tong BMK, Tnay YL, Ng XR, Zhu P, Chiba S, Wang X, Wahli W, Tan NS. Sng MK, et al. Among authors: wahli w. Cell Discov. 2018 Apr 3;4:15. doi: 10.1038/s41421-018-0014-5. eCollection 2018. Cell Discov. 2018. PMID: 29619245 Free PMC article.

29

Collaborative Regulation of LRG1 by TGF-β1 and PPAR-β/δ Modulates Chronic Pressure Overload-Induced Cardiac Fibrosis.

Liu C, Lim ST, Teo MHY, Tan MSY, Kulkarni MD, Qiu B, Li A, Lal S, Dos Remedios CG, Tan NS, Wahli W, Ferenczi MA, Song W, Hong W, Wang X. Liu C, et al. Among authors: wahli w. Circ Heart Fail. 2019 Dec;12(12):e005962. doi: 10.1161/CIRCHEARTFAILURE.119.005962. Epub 2019 Dec 13. Circ Heart Fail. 2019. PMID: 31830829

30

Investigating the Role of PPARβ/δ in Retinal Vascular Remodeling Using Pparβ/δ-Deficient Mice.

Ho SY, Kwan YP, Qiu B, Tan A, Murray HL, Barathi VA, Tan NS, Cheung CMG, Wong TY, Wahli W, Wang X. Ho SY, et al. Among authors: wahli w. Int J Mol Sci. 2020 Jun 20;21(12):4403. doi: 10.3390/ijms21124403. Int J Mol Sci. 2020. PMID: 32575793 Free PMC article.

31

Nuclear receptor peroxisome proliferator activated receptor (PPAR) β/δ in skin wound healing and cancer.

Montagner A, Wahli W, Tan NS. Montagner A, et al. Among authors: wahli w. Eur J Dermatol. 2015 Apr;25 Suppl 1:4-11. doi: 10.1684/ejd.2014.2505. Eur J Dermatol. 2015. PMID: 26287030 Review.

32

In vivo activation of PPAR target genes by RXR homodimers.

IJpenberg A, Tan NS, Gelman L, Kersten S, Seydoux J, Xu J, Metzger D, Canaple L, Chambon P, Wahli W, Desvergne B. IJpenberg A, et al. Among authors: wahli w. EMBO J. 2004 May 19;23(10):2083-91. doi: 10.1038/sj.emboj.7600209. Epub 2004 Apr 22. EMBO J. 2004. PMID: 15103326 Free PMC article.

33

Nuclear hormone receptors and mouse skin homeostasis: implication of PPARbeta.

Michalik L, Desvergne B, Basu-Modak S, Tan NS, Wahli W. Michalik L, et al. Among authors: wahli w. Horm Res. 2000;54(5-6):263-8. doi: 10.1159/000053269. Horm Res. 2000. PMID: 11595815

34

Endothelial-immune crosstalk contributes to vasculopathy in nonalcoholic fatty liver disease.

Ng CY, Lee KL, Muthiah MD, Wu KX, Chioh FWJ, Tan K, Soon GST, Shabbir A, Loo WM, Low ZS, Chen Q, Wahli W, Tan NS, Ng HH, Dan YY, Cheung C. Ng CY, et al. Among authors: wahli w. EMBO Rep. 2022 Oct 6;23(10):e55871. doi: 10.15252/embr.202255871. EMBO Rep. 2022. PMID: 36200589 Free PMC article.

35

The Interleukin-1 receptor antagonist is a direct target gene of PPARalpha in liver.

Stienstra R, Mandard S, Tan NS, Wahli W, Trautwein C, Richardson TA, Lichtenauer-Kaligis E, Kersten S, Müller M. Stienstra R, et al. Among authors: wahli w. J Hepatol. 2007 May;46(5):869-77. doi: 10.1016/j.jhep.2006.11.019. Epub 2006 Dec 26. J Hepatol. 2007. PMID: 17321000 Free article.

36

Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene.

Kersten S, Mandard S, Tan NS, Escher P, Metzger D, Chambon P, Gonzalez FJ, Desvergne B, Wahli W. Kersten S, et al. Among authors: wahli w. J Biol Chem. 2000 Sep 15;275(37):28488-93. doi: 10.1074/jbc.M004029200. J Biol Chem. 2000. PMID: 10862772 Free article.

37

Critical roles of the nuclear receptor PPARbeta (peroxisome-proliferator-activated receptor beta) in skin wound healing.

Tan NS, Michalik L, Di-Poï N, Desvergne B, Wahli W. Tan NS, et al. Among authors: wahli w. Biochem Soc Trans. 2004 Feb;32(Pt 1):97-102. doi: 10.1042/bst0320097. Biochem Soc Trans. 2004. PMID: 14748722 Review.

38

Critical roles of PPAR beta/delta in keratinocyte response to inflammation.

Tan NS, Michalik L, Noy N, Yasmin R, Pacot C, Heim M, Flühmann B, Desvergne B, Wahli W. Tan NS, et al. Among authors: wahli w. Genes Dev. 2001 Dec 15;15(24):3263-77. doi: 10.1101/gad.207501. Genes Dev. 2001. PMID: 11751632 Free PMC article.

39

The direct peroxisome proliferator-activated receptor target fasting-induced adipose factor (FIAF/PGAR/ANGPTL4) is present in blood plasma as a truncated protein that is increased by fenofibrate treatment.

Mandard S, Zandbergen F, Tan NS, Escher P, Patsouris D, Koenig W, Kleemann R, Bakker A, Veenman F, Wahli W, Müller M, Kersten S. Mandard S, et al. Among authors: wahli w. J Biol Chem. 2004 Aug 13;279(33):34411-20. doi: 10.1074/jbc.M403058200. Epub 2004 Jun 9. J Biol Chem. 2004. PMID: 15190076 Free article.

40

The nuclear hormone receptor PPARγ counteracts vascular calcification by inhibiting Wnt5a signalling in vascular smooth muscle cells.

Woldt E, Terrand J, Mlih M, Matz RL, Bruban V, Coudane F, Foppolo S, El Asmar Z, Chollet ME, Ninio E, Bednarczyk A, Thiersé D, Schaeffer C, Van Dorsselaer A, Boudier C, Wahli W, Chambon P, Metzger D, Herz J, Boucher P. Woldt E, et al. Among authors: wahli w. Nat Commun. 2012;3:1077. doi: 10.1038/ncomms2087. Nat Commun. 2012. PMID: 23011131 Free PMC article.

41

The G0/G1 switch gene 2 is a novel PPAR target gene.

Zandbergen F, Mandard S, Escher P, Tan NS, Patsouris D, Jatkoe T, Rojas-Caro S, Madore S, Wahli W, Tafuri S, Müller M, Kersten S. Zandbergen F, et al. Among authors: wahli w. Biochem J. 2005 Dec 1;392(Pt 2):313-24. doi: 10.1042/BJ20050636. Biochem J. 2005. PMID: 16086669 Free PMC article.

42

PPARalpha governs glycerol metabolism.

Patsouris D, Mandard S, Voshol PJ, Escher P, Tan NS, Havekes LM, Koenig W, März W, Tafuri S, Wahli W, Müller M, Kersten S. Patsouris D, et al. Among authors: wahli w. J Clin Invest. 2004 Jul;114(1):94-103. doi: 10.1172/JCI20468. J Clin Invest. 2004. PMID: 15232616 Free PMC article.

43

Role of Dietary Supplements and Probiotics in Modulating Microbiota and Bone Health: The Gut-Bone Axis.

de Sire A, de Sire R, Curci C, Castiglione F, Wahli W. de Sire A, et al. Among authors: wahli w. Cells. 2022 Feb 21;11(4):743. doi: 10.3390/cells11040743. Cells. 2022. PMID: 35203401 Free PMC article. Review.

44

The PPARalpha-leukotriene B4 pathway to inflammation control.

Devchand PR, Keller H, Peters JM, Vazquez M, Gonzalez FJ, Wahli W. Devchand PR, et al. Among authors: wahli w. Nature. 1996 Nov 7;384(6604):39-43. doi: 10.1038/384039a0. Nature. 1996. PMID: 8900274

45

The gut microbiota influences skeletal muscle mass and function in mice.

Lahiri S, Kim H, Garcia-Perez I, Reza MM, Martin KA, Kundu P, Cox LM, Selkrig J, Posma JM, Zhang H, Padmanabhan P, Moret C, Gulyás B, Blaser MJ, Auwerx J, Holmes E, Nicholson J, Wahli W, Pettersson S. Lahiri S, et al. Among authors: wahli w. Sci Transl Med. 2019 Jul 24;11(502):eaan5662. doi: 10.1126/scitranslmed.aan5662. Sci Transl Med. 2019. PMID: 31341063 Free PMC article.

46

The pregnane X receptor drives sexually dimorphic hepatic changes in lipid and xenobiotic metabolism in response to gut microbiota in mice.

Barretto SA, Lasserre F, Huillet M, Régnier M, Polizzi A, Lippi Y, Fougerat A, Person E, Bruel S, Bétoulières C, Naylies C, Lukowicz C, Smati S, Guzylack L, Olier M, Théodorou V, Mselli-Lakhal L, Zalko D, Wahli W, Loiseau N, Gamet-Payrastre L, Guillou H, Ellero-Simatos S. Barretto SA, et al. Among authors: wahli w. Microbiome. 2021 Apr 20;9(1):93. doi: 10.1186/s40168-021-01050-9. Microbiome. 2021. PMID: 33879258 Free PMC article.

47

Roles of PPARs in health and disease.

Kersten S, Desvergne B, Wahli W. Kersten S, et al. Among authors: wahli w. Nature. 2000 May 25;405(6785):421-4. doi: 10.1038/35013000. Nature. 2000. PMID: 10839530 Review.

48

The peroxisomal enzyme L-PBE is required to prevent the dietary toxicity of medium-chain fatty acids.

Ding J, Loizides-Mangold U, Rando G, Zoete V, Michielin O, Reddy JK, Wahli W, Riezman H, Thorens B. Ding J, et al. Among authors: wahli w. Cell Rep. 2013 Oct 17;5(1):248-58. doi: 10.1016/j.celrep.2013.08.032. Epub 2013 Sep 26. Cell Rep. 2013. PMID: 24075987 Free article.

49

Liver gene expression and its rewiring in hepatic steatosis are controlled by PI3Kα-dependent hepatocyte signaling.

Régnier M, Polizzi A, Fougeray T, Fougerat A, Perrier P, Anderson K, Lippi Y, Smati S, Lukowicz C, Lasserre F, Fouche E, Huillet M, Rives C, Tramunt B, Naylies C, Garcia G, Rousseau-Bacquié E, Bertrand-Michel J, Canlet C, Chevolleau-Mege S, Debrauwer L, Heymes C, Burcelin R, Levade T, Gourdy P, Wahli W, Blum Y, Gamet-Payrastre L, Ellero-Simatos S, Guillermet-Guibert J, Hawkins P, Stephens L, Postic C, Montagner A, Loiseau N, Guillou H. Régnier M, et al. Among authors: wahli w. PLoS Biol. 2025 Apr 14;23(4):e3003112. doi: 10.1371/journal.pbio.3003112. eCollection 2025 Apr. PLoS Biol. 2025. PMID: 40228209 Free PMC article.

50

The PPAR-microbiota-metabolic organ trilogy to fine-tune physiology.

Oh HYP, Visvalingam V, Wahli W. Oh HYP, et al. Among authors: wahli w. FASEB J. 2019 Sep;33(9):9706-9730. doi: 10.1096/fj.201802681RR. Epub 2019 Jun 25. FASEB J. 2019. PMID: 31237779 Review.

Knowing that the gut microbiota impacts metabolism and is altered in individuals with metabolic diseases might allow treatment of these patients using noninvasive procedures such as gut microbiota manipulation.-Oh, H. Y. P., Visvalingam, V., Wahli, W. The PPAR-micro …

Knowing that the gut microbiota impacts metabolism and is altered in individuals with metabolic diseases might allow treatment of these pati …

51

Reciprocal regulation of brain and muscle Arnt-like protein 1 and peroxisome proliferator-activated receptor alpha defines a novel positive feedback loop in the rodent liver circadian clock.

Canaple L, Rambaud J, Dkhissi-Benyahya O, Rayet B, Tan NS, Michalik L, Delaunay F, Wahli W, Laudet V. Canaple L, et al. Among authors: wahli w. Mol Endocrinol. 2006 Aug;20(8):1715-27. doi: 10.1210/me.2006-0052. Epub 2006 Mar 23. Mol Endocrinol. 2006. PMID: 16556735

52

Complementary intestinal mucosa and microbiota responses to caloric restriction.

Duszka K, Ellero-Simatos S, Ow GS, Defernez M, Paramalingam E, Tett A, Ying S, König J, Narbad A, Kuznetsov VA, Guillou H, Wahli W. Duszka K, et al. Among authors: wahli w. Sci Rep. 2018 Jul 27;8(1):11338. doi: 10.1038/s41598-018-29815-7. Sci Rep. 2018. PMID: 30054525 Free PMC article.

53

PPARs and Microbiota in Skeletal Muscle Health and Wasting.

Manickam R, Duszka K, Wahli W. Manickam R, et al. Among authors: wahli w. Int J Mol Sci. 2020 Oct 29;21(21):8056. doi: 10.3390/ijms21218056. Int J Mol Sci. 2020. PMID: 33137899 Free PMC article. Review.

54

Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target.

Smati S, Polizzi A, Fougerat A, Ellero-Simatos S, Blum Y, Lippi Y, Régnier M, Laroyenne A, Huillet M, Arif M, Zhang C, Lasserre F, Marrot A, Al Saati T, Wan J, Sommer C, Naylies C, Batut A, Lukowicz C, Fougeray T, Tramunt B, Dubot P, Smith L, Bertrand-Michel J, Hennuyer N, Pradere JP, Staels B, Burcelin R, Lenfant F, Arnal JF, Levade T, Gamet-Payrastre L, Lagarrigue S, Loiseau N, Lotersztajn S, Postic C, Wahli W, Bureau C, Guillaume M, Mardinoglu A, Montagner A, Gourdy P, Guillou H. Smati S, et al. Among authors: wahli w. Gut. 2022 Apr;71(4):807-821. doi: 10.1136/gutjnl-2020-323323. Epub 2021 Apr 26. Gut. 2022. PMID: 33903148 Free article.

55

Peroxisome Proliferator-Activated Receptors and Their Novel Ligands as Candidates for the Treatment of Non-Alcoholic Fatty Liver Disease.

Fougerat A, Montagner A, Loiseau N, Guillou H, Wahli W. Fougerat A, et al. Among authors: wahli w. Cells. 2020 Jul 8;9(7):1638. doi: 10.3390/cells9071638. Cells. 2020. PMID: 32650421 Free PMC article. Review.

56

Oxidative Stress in NAFLD: Role of Nutrients and Food Contaminants.

Rives C, Fougerat A, Ellero-Simatos S, Loiseau N, Guillou H, Gamet-Payrastre L, Wahli W. Rives C, et al. Among authors: wahli w. Biomolecules. 2020 Dec 21;10(12):1702. doi: 10.3390/biom10121702. Biomolecules. 2020. PMID: 33371482 Free PMC article. Review.

57

Peroxisome Proliferator-Activated Receptors and Caloric Restriction-Common Pathways Affecting Metabolism, Health, and Longevity.

Duszka K, Gregor A, Guillou H, König J, Wahli W. Duszka K, et al. Among authors: wahli w. Cells. 2020 Jul 16;9(7):1708. doi: 10.3390/cells9071708. Cells. 2020. PMID: 32708786 Free PMC article. Review.

58

Pharmacological PPARβ/δ activation upregulates VLDLR in hepatocytes.

Zarei M, Barroso E, Palomer X, Escolà-Gil JC, Cedó L, Wahli W, Vázquez-Carrera M. Zarei M, et al. Among authors: wahli w. Clin Investig Arterioscler. 2019 May-Jun;31(3):111-118. doi: 10.1016/j.arteri.2019.01.004. Epub 2019 Apr 13. Clin Investig Arterioscler. 2019. PMID: 30987865 English, Spanish.

59

Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant mice.

Michalik L, Desvergne B, Tan NS, Basu-Modak S, Escher P, Rieusset J, Peters JM, Kaya G, Gonzalez FJ, Zakany J, Metzger D, Chambon P, Duboule D, Wahli W. Michalik L, et al. Among authors: wahli w. J Cell Biol. 2001 Aug 20;154(4):799-814. doi: 10.1083/jcb.200011148. J Cell Biol. 2001. PMID: 11514592 Free PMC article.

60

Roles of Peroxisome Proliferator-Activated Receptor β/δ in skeletal muscle physiology.

Manickam R, Wahli W. Manickam R, et al. Among authors: wahli w. Biochimie. 2017 May;136:42-48. doi: 10.1016/j.biochi.2016.11.010. Epub 2016 Dec 2. Biochimie. 2017. PMID: 27916646 Review.

61

Insights into the role of hepatocyte PPARα activity in response to fasting.

Régnier M, Polizzi A, Lippi Y, Fouché E, Michel G, Lukowicz C, Smati S, Marrot A, Lasserre F, Naylies C, Batut A, Viars F, Bertrand-Michel J, Postic C, Loiseau N, Wahli W, Guillou H, Montagner A. Régnier M, et al. Among authors: wahli w. Mol Cell Endocrinol. 2018 Aug 15;471:75-88. doi: 10.1016/j.mce.2017.07.035. Epub 2017 Jul 31. Mol Cell Endocrinol. 2018. PMID: 28774777

62

The PPARβ/δ-AMPK Connection in the Treatment of Insulin Resistance.

Aguilar-Recarte D, Palomer X, Wahli W, Vázquez-Carrera M. Aguilar-Recarte D, et al. Among authors: wahli w. Int J Mol Sci. 2021 Aug 9;22(16):8555. doi: 10.3390/ijms22168555. Int J Mol Sci. 2021. PMID: 34445261 Free PMC article. Review.

63

Regulation of hepatokine gene expression in response to fasting and feeding: Influence of PPAR-α and insulin-dependent signalling in hepatocytes.

Smati S, Régnier M, Fougeray T, Polizzi A, Fougerat A, Lasserre F, Lukowicz C, Tramunt B, Guillaume M, Burnol AF, Postic C, Wahli W, Montagner A, Gourdy P, Guillou H. Smati S, et al. Among authors: wahli w. Diabetes Metab. 2020 Apr;46(2):129-136. doi: 10.1016/j.diabet.2019.05.005. Epub 2019 Jun 1. Diabetes Metab. 2020. PMID: 31163275

64

Hepatic regulation of VLDL receptor by PPARβ/δ and FGF21 modulates non-alcoholic fatty liver disease.

Zarei M, Barroso E, Palomer X, Dai J, Rada P, Quesada-López T, Escolà-Gil JC, Cedó L, Zali MR, Molaei M, Dabiri R, Vázquez S, Pujol E, Valverde ÁM, Villarroya F, Liu Y, Wahli W, Vázquez-Carrera M. Zarei M, et al. Among authors: wahli w. Mol Metab. 2018 Feb;8:117-131. doi: 10.1016/j.molmet.2017.12.008. Epub 2017 Dec 19. Mol Metab. 2018. PMID: 29289645 Free PMC article.

65

Metronidazole Causes Skeletal Muscle Atrophy and Modulates Muscle Chronometabolism.

Manickam R, Oh HYP, Tan CK, Paramalingam E, Wahli W. Manickam R, et al. Among authors: wahli w. Int J Mol Sci. 2018 Aug 16;19(8):2418. doi: 10.3390/ijms19082418. Int J Mol Sci. 2018. PMID: 30115857 Free PMC article.

66

Hepatocyte-specific deletion of Pparα promotes NAFLD in the context of obesity.

Régnier M, Polizzi A, Smati S, Lukowicz C, Fougerat A, Lippi Y, Fouché E, Lasserre F, Naylies C, Bétoulières C, Barquissau V, Mouisel E, Bertrand-Michel J, Batut A, Saati TA, Canlet C, Tremblay-Franco M, Ellero-Simatos S, Langin D, Postic C, Wahli W, Loiseau N, Guillou H, Montagner A. Régnier M, et al. Among authors: wahli w. Sci Rep. 2020 Apr 16;10(1):6489. doi: 10.1038/s41598-020-63579-3. Sci Rep. 2020. PMID: 32300166 Free PMC article.

67

Peroxisome proliferator-activated receptor beta/delta as a therapeutic target for metabolic diseases.

Bedu E, Wahli W, Desvergne B. Bedu E, et al. Among authors: wahli w. Expert Opin Ther Targets. 2005 Aug;9(4):861-73. doi: 10.1517/14728222.9.4.861. Expert Opin Ther Targets. 2005. PMID: 16083348 Review.

68

Adipose-Specific PPARα Knockout Mice Have Increased Lipogenesis by PASK-SREBP1 Signaling and a Polarity Shift to Inflammatory Macrophages in White Adipose Tissue.

Hinds TD Jr, Kipp ZA, Xu M, Yiannikouris FB, Morris AJ, Stec DF, Wahli W, Stec DE. Hinds TD Jr, et al. Among authors: wahli w. Cells. 2021 Dec 21;11(1):4. doi: 10.3390/cells11010004. Cells. 2021. PMID: 35011564 Free PMC article.

69

Dual PPARα/γ agonist saroglitazar improves liver histopathology and biochemistry in experimental NASH models.

Jain MR, Giri SR, Bhoi B, Trivedi C, Rath A, Rathod R, Ranvir R, Kadam S, Patel H, Swain P, Roy SS, Das N, Karmakar E, Wahli W, Patel PR. Jain MR, et al. Among authors: wahli w. Liver Int. 2018 Jun;38(6):1084-1094. doi: 10.1111/liv.13634. Epub 2017 Dec 14. Liver Int. 2018. PMID: 29164820 Free PMC article.

70

Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD.

Montagner A, Polizzi A, Fouché E, Ducheix S, Lippi Y, Lasserre F, Barquissau V, Régnier M, Lukowicz C, Benhamed F, Iroz A, Bertrand-Michel J, Al Saati T, Cano P, Mselli-Lakhal L, Mithieux G, Rajas F, Lagarrigue S, Pineau T, Loiseau N, Postic C, Langin D, Wahli W, Guillou H. Montagner A, et al. Among authors: wahli w. Gut. 2016 Jul;65(7):1202-14. doi: 10.1136/gutjnl-2015-310798. Epub 2016 Feb 1. Gut. 2016. PMID: 26838599 Free PMC article.

71

Hepatic Fasting-Induced PPARα Activity Does Not Depend on Essential Fatty Acids.

Polizzi A, Fouché E, Ducheix S, Lasserre F, Marmugi AP, Mselli-Lakhal L, Loiseau N, Wahli W, Guillou H, Montagner A. Polizzi A, et al. Among authors: wahli w. Int J Mol Sci. 2016 Sep 24;17(10):1624. doi: 10.3390/ijms17101624. Int J Mol Sci. 2016. PMID: 27669233 Free PMC article.

72

Exploring Extracellular Vesicles Biogenesis in Hypothalamic Cells through a Heavy Isotope Pulse/Trace Proteomic Approach.

Tan CF, Teo HS, Park JE, Dutta B, Tse SW, Leow MK, Wahli W, Sze SK. Tan CF, et al. Among authors: wahli w. Cells. 2020 May 25;9(5):1320. doi: 10.3390/cells9051320. Cells. 2020. PMID: 32466345 Free PMC article.

73

Peroxisome Proliferator-Activated Receptors as Molecular Links between Caloric Restriction and Circadian Rhythm.

Duszka K, Wahli W. Duszka K, et al. Among authors: wahli w. Nutrients. 2020 Nov 12;12(11):3476. doi: 10.3390/nu12113476. Nutrients. 2020. PMID: 33198317 Free PMC article. Review.

74

Nuclear HMGB1 protects from nonalcoholic fatty liver disease through negative regulation of liver X receptor.

Personnaz J, Piccolo E, Dortignac A, Iacovoni JS, Mariette J, Rocher V, Polizzi A, Batut A, Deleruyelle S, Bourdens L, Delos O, Combes-Soia L, Paccoud R, Moreau E, Martins F, Clouaire T, Benhamed F, Montagner A, Wahli W, Schwabe RF, Yart A, Castan-Laurell I, Bertrand-Michel J, Burlet-Schiltz O, Postic C, Denechaud PD, Moro C, Legube G, Lee CH, Guillou H, Valet P, Dray C, Pradère JP. Personnaz J, et al. Among authors: wahli w. Sci Adv. 2022 Mar 25;8(12):eabg9055. doi: 10.1126/sciadv.abg9055. Epub 2022 Mar 25. Sci Adv. 2022. PMID: 35333579 Free PMC article.

75

Hepatic PPARα is critical in the metabolic adaptation to sepsis.

Paumelle R, Haas JT, Hennuyer N, Baugé E, Deleye Y, Mesotten D, Langouche L, Vanhoutte J, Cudejko C, Wouters K, Hannou SA, Legry V, Lancel S, Lalloyer F, Polizzi A, Smati S, Gourdy P, Vallez E, Bouchaert E, Derudas B, Dehondt H, Gheeraert C, Fleury S, Tailleux A, Montagner A, Wahli W, Van Den Berghe G, Guillou H, Dombrowicz D, Staels B. Paumelle R, et al. Among authors: wahli w. J Hepatol. 2019 May;70(5):963-973. doi: 10.1016/j.jhep.2018.12.037. Epub 2019 Jan 21. J Hepatol. 2019. PMID: 30677458 Free PMC article.

76

GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPK.

Aguilar-Recarte D, Barroso E, Gumà A, Pizarro-Delgado J, Peña L, Ruart M, Palomer X, Wahli W, Vázquez-Carrera M. Aguilar-Recarte D, et al. Among authors: wahli w. Cell Rep. 2021 Aug 10;36(6):109501. doi: 10.1016/j.celrep.2021.109501. Cell Rep. 2021. PMID: 34380027 Free article.

77

Enteric Microbiota⁻Gut⁻Brain Axis from the Perspective of Nuclear Receptors.

Duszka K, Wahli W. Duszka K, et al. Among authors: wahli w. Int J Mol Sci. 2018 Jul 28;19(8):2210. doi: 10.3390/ijms19082210. Int J Mol Sci. 2018. PMID: 30060580 Free PMC article. Review.

78

PPARγ Modulates Long Chain Fatty Acid Processing in the Intestinal Epithelium.

Duszka K, Oresic M, Le May C, König J, Wahli W. Duszka K, et al. Among authors: wahli w. Int J Mol Sci. 2017 Nov 28;18(12):2559. doi: 10.3390/ijms18122559. Int J Mol Sci. 2017. PMID: 29182565 Free PMC article.

79

Glucocorticoid receptor-PPARα axis in fetal mouse liver prepares neonates for milk lipid catabolism.

Rando G, Tan CK, Khaled N, Montagner A, Leuenberger N, Bertrand-Michel J, Paramalingam E, Guillou H, Wahli W. Rando G, et al. Among authors: wahli w. Elife. 2016 Jul 1;5:e11853. doi: 10.7554/eLife.11853. Elife. 2016. PMID: 27367842 Free PMC article.

80

Heme-Regulated eIF2α Kinase Modulates Hepatic FGF21 and Is Activated by PPARβ/δ Deficiency.

Zarei M, Barroso E, Leiva R, Barniol-Xicota M, Pujol E, Escolano C, Vázquez S, Palomer X, Pardo V, González-Rodríguez Á, Valverde ÁM, Quesada-López T, Villarroya F, Wahli W, Vázquez-Carrera M. Zarei M, et al. Among authors: wahli w. Diabetes. 2016 Oct;65(10):3185-99. doi: 10.2337/db16-0155. Epub 2016 Aug 2. Diabetes. 2016. PMID: 27486236

81

The OEA effect on food intake is independent from the presence of PPARα in the intestine and the nodose ganglion, while the impact of OEA on energy expenditure requires the presence of PPARα in mice.

Caillon A, Duszka K, Wahli W, Rohner-Jeanrenaud F, Altirriba J. Caillon A, et al. Among authors: wahli w. Metabolism. 2018 Oct;87:13-17. doi: 10.1016/j.metabol.2018.06.005. Epub 2018 Jun 21. Metabolism. 2018. PMID: 29936173

82

Synthetic and natural Peroxisome Proliferator-Activated Receptor (PPAR) agonists as candidates for the therapy of the metabolic syndrome.

Tan CK, Zhuang Y, Wahli W. Tan CK, et al. Among authors: wahli w. Expert Opin Ther Targets. 2017 Mar;21(3):333-348. doi: 10.1080/14728222.2017.1280467. Epub 2017 Jan 25. Expert Opin Ther Targets. 2017. PMID: 28092722 Review.

83

Hepatic circadian clock oscillators and nuclear receptors integrate microbiome-derived signals.

Montagner A, Korecka A, Polizzi A, Lippi Y, Blum Y, Canlet C, Tremblay-Franco M, Gautier-Stein A, Burcelin R, Yen YC, Je HS, Al-Asmakh M, Mithieux G, Arulampalam V, Lagarrigue S, Guillou H, Pettersson S, Wahli W. Montagner A, et al. Among authors: wahli w. Sci Rep. 2016 Feb 16;6:20127. doi: 10.1038/srep20127. Sci Rep. 2016. PMID: 26879573 Free PMC article.

84

Adipose tissue integrity as a prerequisite for systemic energy balance: a critical role for peroxisome proliferator-activated receptor gamma.

Anghel SI, Bedu E, Vivier CD, Descombes P, Desvergne B, Wahli W. Anghel SI, et al. Among authors: wahli w. J Biol Chem. 2007 Oct 12;282(41):29946-57. doi: 10.1074/jbc.M702490200. Epub 2007 Aug 14. J Biol Chem. 2007. PMID: 17699161 Free article.

85

PPARbeta/delta regulates paneth cell differentiation via controlling the hedgehog signaling pathway.

Varnat F, Heggeler BB, Grisel P, Boucard N, Corthésy-Theulaz I, Wahli W, Desvergne B. Varnat F, et al. Among authors: wahli w. Gastroenterology. 2006 Aug;131(2):538-53. doi: 10.1053/j.gastro.2006.05.004. Gastroenterology. 2006. PMID: 16890607

86

Glycogen synthase 2 is a novel target gene of peroxisome proliferator-activated receptors.

Mandard S, Stienstra R, Escher P, Tan NS, Kim I, Gonzalez FJ, Wahli W, Desvergne B, Müller M, Kersten S. Mandard S, et al. Among authors: wahli w. Cell Mol Life Sci. 2007 May;64(9):1145-57. doi: 10.1007/s00018-007-7006-1. Cell Mol Life Sci. 2007. PMID: 17437057 Free PMC article.

87

Absence of intestinal PPARγ aggravates acute infectious colitis in mice through a lipocalin-2-dependent pathway.

Kundu P, Ling TW, Korecka A, Li Y, D'Arienzo R, Bunte RM, Berger T, Arulampalam V, Chambon P, Mak TW, Wahli W, Pettersson S. Kundu P, et al. Among authors: wahli w. PLoS Pathog. 2014 Jan;10(1):e1003887. doi: 10.1371/journal.ppat.1003887. Epub 2014 Jan 23. PLoS Pathog. 2014. PMID: 24465207 Free PMC article.

88

Peroxisome Proliferator Activated Receptor Gamma Controls Mature Brown Adipocyte Inducibility through Glycerol Kinase.

Lasar D, Rosenwald M, Kiehlmann E, Balaz M, Tall B, Opitz L, Lidell ME, Zamboni N, Krznar P, Sun W, Varga L, Stefanicka P, Ukropec J, Nuutila P, Virtanen K, Amri EZ, Enerbäck S, Wahli W, Wolfrum C. Lasar D, et al. Among authors: wahli w. Cell Rep. 2018 Jan 16;22(3):760-773. doi: 10.1016/j.celrep.2017.12.067. Cell Rep. 2018. PMID: 29346772 Free article.

89

The Role of PPARβ/δ in Melanoma Metastasis.

Lim JCW, Kwan YP, Tan MS, Teo MHY, Chiba S, Wahli W, Wang X. Lim JCW, et al. Among authors: wahli w. Int J Mol Sci. 2018 Sep 20;19(10):2860. doi: 10.3390/ijms19102860. Int J Mol Sci. 2018. PMID: 30241392 Free PMC article.

90

Invalidation of the Transcriptional Modulator of Lipid Metabolism PPARβ/δ in T Cells Prevents Age-Related Alteration of Body Composition and Loss of Endurance Capacity.

Rousseau AS, Murdaca J, Le Menn G, Sibille B, Wahli W, Le Garf S, Chinetti G, Neels JG, Mothe-Satney I. Rousseau AS, et al. Among authors: wahli w. Front Physiol. 2021 Mar 17;12:587753. doi: 10.3389/fphys.2021.587753. eCollection 2021. Front Physiol. 2021. PMID: 33815130 Free PMC article.

91

Peroxisome Proliferator-Activated Receptor β/δ: A Link Between Metabolism, Inflammation, and Fibrosis in Metabolic Dysfunction-Associated Steatotic Liver Disease.

Palomer X, Wang JR, Tang X, Wu S, Rodríguez-Calvo R, Wahli W, Vázquez-Carrera M. Palomer X, et al. Among authors: wahli w. Cells. 2026 Mar 5;15(5):464. doi: 10.3390/cells15050464. Cells. 2026. PMID: 41827897 Free PMC article. Review.

92

Lack of Smad3 signaling leads to impaired skeletal muscle regeneration.

Ge X, Vajjala A, McFarlane C, Wahli W, Sharma M, Kambadur R. Ge X, et al. Among authors: wahli w. Am J Physiol Endocrinol Metab. 2012 Jul 1;303(1):E90-102. doi: 10.1152/ajpendo.00113.2012. Epub 2012 Apr 24. Am J Physiol Endocrinol Metab. 2012. PMID: 22535746 Free article.

93

A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 Response.

Iroz A, Montagner A, Benhamed F, Levavasseur F, Polizzi A, Anthony E, Régnier M, Fouché E, Lukowicz C, Cauzac M, Tournier E, Do-Cruzeiro M, Daujat-Chavanieu M, Gerbal-Chalouin S, Fauveau V, Marmier S, Burnol AF, Guilmeau S, Lippi Y, Girard J, Wahli W, Dentin R, Guillou H, Postic C. Iroz A, et al. Among authors: wahli w. Cell Rep. 2017 Oct 10;21(2):403-416. doi: 10.1016/j.celrep.2017.09.065. Cell Rep. 2017. PMID: 29020627 Free PMC article.

94

Functions of the peroxisome proliferator-activated receptor (PPAR) alpha and beta in skin homeostasis, epithelial repair, and morphogenesis.

Icre G, Wahli W, Michalik L. Icre G, et al. Among authors: wahli w. J Investig Dermatol Symp Proc. 2006 Sep;11(1):30-5. doi: 10.1038/sj.jidsymp.5650007. J Investig Dermatol Symp Proc. 2006. PMID: 17069008 Free article. Review.

95

Knocking on GDF15's door for the treatment of type 2 diabetes mellitus.

Aguilar-Recarte D, Barroso E, Palomer X, Wahli W, Vázquez-Carrera M. Aguilar-Recarte D, et al. Among authors: wahli w. Trends Endocrinol Metab. 2022 Nov;33(11):741-754. doi: 10.1016/j.tem.2022.08.004. Epub 2022 Sep 20. Trends Endocrinol Metab. 2022. PMID: 36151002 Review.

96

PPARs as Key Transcription Regulators at the Crossroads of Metabolism and Inflammation.

Vázquez-Carrera M, Wahli W. Vázquez-Carrera M, et al. Among authors: wahli w. Int J Mol Sci. 2024 Apr 18;25(8):4467. doi: 10.3390/ijms25084467. Int J Mol Sci. 2024. PMID: 38674052 Free PMC article.

97

Hepatic FGF21 is not required for fasting metabolism but guides protein appetite post energy depletion.

Bruse J, Marbach C, Polizzi A, Landre T, Salvi J, Alquier-Bacquie V, Chen SP, Huillet M, Rives C, Martin CMP, Perrier P, Benhamed F, Régnier M, Weger S, Naylies C, Lippi Y, Sommer C, Albin M, Lasserre F, Levade T, Schupp M, Gamet-Payrastre L, Kautz L, Loiseau N, Wahli W, Ellero-Simatos S, Cruciani-Guglielmacci C, Montagner A, Benani A, Postic C, Guillou H, Fougerat A. Bruse J, et al. Among authors: wahli w. EMBO Rep. 2026 Apr 27. doi: 10.1038/s44319-026-00790-9. Online ahead of print. EMBO Rep. 2026. PMID: 42045447 Free article.

98

ATGL-dependent white adipose tissue lipolysis controls hepatocyte PPARα activity.

Fougerat A, Schoiswohl G, Polizzi A, Régnier M, Wagner C, Smati S, Fougeray T, Lippi Y, Lasserre F, Raho I, Melin V, Tramunt B, Métivier R, Sommer C, Benhamed F, Alkhoury C, Greulich F, Jouffe C, Emile A, Schupp M, Gourdy P, Dubot P, Levade T, Meynard D, Ellero-Simatos S, Gamet-Payrastre L, Panasyuk G, Uhlenhaut H, Amri EZ, Cruciani-Guglielmacci C, Postic C, Wahli W, Loiseau N, Montagner A, Langin D, Lass A, Guillou H. Fougerat A, et al. Among authors: wahli w. Cell Rep. 2022 Jun 7;39(10):110910. doi: 10.1016/j.celrep.2022.110910. Cell Rep. 2022. PMID: 35675775 Free article.

99

PPARs at the crossroads of lipid signaling and inflammation.

Wahli W, Michalik L. Wahli W, et al. Trends Endocrinol Metab. 2012 Jul;23(7):351-63. doi: 10.1016/j.tem.2012.05.001. Epub 2012 Jun 14. Trends Endocrinol Metab. 2012. PMID: 22704720 Review.

100

PPARs as Key Mediators in the Regulation of Metabolism and Inflammation.

Vázquez-Carrera M, Wahli W. Vázquez-Carrera M, et al. Among authors: wahli w. Int J Mol Sci. 2022 Apr 30;23(9):5025. doi: 10.3390/ijms23095025. Int J Mol Sci. 2022. PMID: 35563416 Free PMC article.

101

The Opioid Receptor Influences Circadian Rhythms in Human Keratinocytes through the β-Arrestin Pathway.

Bigliardi P, Junnarkar S, Markale C, Lo S, Bigliardi E, Kalyuzhny A, Ong S, Dunn R, Wahli W, Bigliardi-Qi M. Bigliardi P, et al. Among authors: wahli w. Cells. 2024 Jan 25;13(3):232. doi: 10.3390/cells13030232. Cells. 2024. PMID: 38334624 Free PMC article.

102

Beneficial effects of combinatorial micronutrition on body fat and atherosclerosis in mice.

El Kochairi I, Montagner A, Rando G, Lohmann C, Matter CM, Wahli W. El Kochairi I, et al. Among authors: wahli w. Cardiovasc Res. 2011 Sep 1;91(4):732-41. doi: 10.1093/cvr/cvr146. Epub 2011 May 28. Cardiovasc Res. 2011. PMID: 21622975 Free PMC article.

103

Peroxisome proliferator-activated receptor β/δ induces myogenesis by modulating myostatin activity.

Bonala S, Lokireddy S, Arigela H, Teng S, Wahli W, Sharma M, McFarlane C, Kambadur R. Bonala S, et al. Among authors: wahli w. J Biol Chem. 2012 Apr 13;287(16):12935-51. doi: 10.1074/jbc.M111.319145. Epub 2012 Feb 23. J Biol Chem. 2012. Retraction in: J Biol Chem. 2016 Jul 1;291(27):14391. doi: 10.1074/jbc.A111.319145. PMID: 22362769 Free PMC article. Retracted.

104

PPARβ interprets a chromatin signature of pluripotency to promote embryonic differentiation at gastrulation.

Rotman N, Guex N, Gouranton E, Wahli W. Rotman N, et al. Among authors: wahli w. PLoS One. 2013 Dec 18;8(12):e83300. doi: 10.1371/journal.pone.0083300. eCollection 2013. PLoS One. 2013. PMID: 24367589 Free PMC article.

105

PPARα Is Required for PPARδ Action in Regulation of Body Weight and Hepatic Steatosis in Mice.

Garbacz WG, Huang JT, Higgins LG, Wahli W, Palmer CN. Garbacz WG, et al. Among authors: wahli w. PPAR Res. 2015;2015:927057. doi: 10.1155/2015/927057. Epub 2015 Oct 29. PPAR Res. 2015. PMID: 26604919 Free PMC article.

106

A trilogy of glucocorticoid receptor actions.

Tan CK, Wahli W. Tan CK, et al. Among authors: wahli w. Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1115-7. doi: 10.1073/pnas.1524215113. Epub 2016 Jan 20. Proc Natl Acad Sci U S A. 2016. PMID: 26792523 Free PMC article. No abstract available.

107

Cyclooxygenase-2 Selectively Controls Renal Blood Flow Through a Novel PPARβ/δ-Dependent Vasodilator Pathway.

Kirkby NS, Sampaio W, Etelvino G, Alves DT, Anders KL, Temponi R, Shala F, Nair AS, Ahmetaj-Shala B, Jiao J, Herschman HR, Wang X, Wahli W, Santos RA, Mitchell JA. Kirkby NS, et al. Among authors: wahli w. Hypertension. 2018 Feb;71(2):297-305. doi: 10.1161/HYPERTENSIONAHA.117.09906. Epub 2018 Jan 2. Hypertension. 2018. PMID: 29295852 Free PMC article.

108

LRG1 Promotes Metastatic Dissemination of Melanoma through Regulating EGFR/STAT3 Signalling.

Kwan YP, Teo MHY, Lim JCW, Tan MS, Rosellinny G, Wahli W, Wang X. Kwan YP, et al. Among authors: wahli w. Cancers (Basel). 2021 Jun 30;13(13):3279. doi: 10.3390/cancers13133279. Cancers (Basel). 2021. PMID: 34208965 Free PMC article.

109

Peroxisomal Proliferator-Activated Receptor β/δ Deficiency Induces Cognitive Alterations.

Espinosa-Jiménez T, Busquets O, Cano A, Sánchez-López E, Verdaguer E, Parcerisas A, Olloquequi J, Auladell C, Folch J, Wahli W, Vázquez-Carrera M, Camins A, Ettcheto M. Espinosa-Jiménez T, et al. Among authors: wahli w. Front Pharmacol. 2022 Jul 11;13:902047. doi: 10.3389/fphar.2022.902047. eCollection 2022. Front Pharmacol. 2022. PMID: 35899125 Free PMC article.

110

PPARβ/δ attenuates palmitate-induced endoplasmic reticulum stress and induces autophagic markers in human cardiac cells.

Palomer X, Capdevila-Busquets E, Botteri G, Salvadó L, Barroso E, Davidson MM, Michalik L, Wahli W, Vázquez-Carrera M. Palomer X, et al. Among authors: wahli w. Int J Cardiol. 2014 Jun 1;174(1):110-8. doi: 10.1016/j.ijcard.2014.03.176. Epub 2014 Apr 8. Int J Cardiol. 2014. PMID: 24767130

111

PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice.

Iglesias J, Barg S, Vallois D, Lahiri S, Roger C, Yessoufou A, Pradevand S, McDonald A, Bonal C, Reimann F, Gribble F, Debril MB, Metzger D, Chambon P, Herrera P, Rutter GA, Prentki M, Thorens B, Wahli W. Iglesias J, et al. Among authors: wahli w. J Clin Invest. 2012 Nov;122(11):4105-17. doi: 10.1172/JCI42127. Epub 2012 Oct 24. J Clin Invest. 2012. PMID: 23093780 Free PMC article.

112

Pancreatic islet adaptation to fasting is dependent on peroxisome proliferator-activated receptor alpha transcriptional up-regulation of fatty acid oxidation.

Gremlich S, Nolan C, Roduit R, Burcelin R, Peyot ML, Delghingaro-Augusto V, Desvergne B, Michalik L, Prentki M, Wahli W. Gremlich S, et al. Among authors: wahli w. Endocrinology. 2005 Jan;146(1):375-82. doi: 10.1210/en.2004-0667. Epub 2004 Sep 30. Endocrinology. 2005. PMID: 15459119

113

New insights into the role of PPARs.

Montagner A, Rando G, Degueurce G, Leuenberger N, Michalik L, Wahli W. Montagner A, et al. Among authors: wahli w. Prostaglandins Leukot Essent Fatty Acids. 2011 Nov;85(5):235-43. doi: 10.1016/j.plefa.2011.04.016. Epub 2011 Jul 20. Prostaglandins Leukot Essent Fatty Acids. 2011. PMID: 21778043 Review.

114

PPAR modulation of kinase-linked receptor signaling in physiology and disease.

Rotman N, Wahli W. Rotman N, et al. Among authors: wahli w. Physiology (Bethesda). 2010 Jun;25(3):176-85. doi: 10.1152/physiol.00018.2010. Physiology (Bethesda). 2010. PMID: 20551231 Free article. Review.

115

Peroxisome-proliferator-activated receptors and cancers: complex stories.

Michalik L, Desvergne B, Wahli W. Michalik L, et al. Among authors: wahli w. Nat Rev Cancer. 2004 Jan;4(1):61-70. doi: 10.1038/nrc1254. Nat Rev Cancer. 2004. PMID: 14708026 Review. No abstract available.

116

The hepatocyte insulin receptor is required to program the liver clock and rhythmic gene expression.

Fougeray T, Polizzi A, Régnier M, Fougerat A, Ellero-Simatos S, Lippi Y, Smati S, Lasserre F, Tramunt B, Huillet M, Dopavogui L, Salvi J, Nédélec E, Gigot V, Smith L, Naylies C, Sommer C, Haas JT, Wahli W, Duez H, Gourdy P, Gamet-Payrastre L, Benani A, Burnol AF, Loiseau N, Postic C, Montagner A, Guillou H. Fougeray T, et al. Among authors: wahli w. Cell Rep. 2022 Apr 12;39(2):110674. doi: 10.1016/j.celrep.2022.110674. Cell Rep. 2022. PMID: 35417722 Free article.

117

The endocrine disruptor monoethyl-hexyl-phthalate is a selective peroxisome proliferator-activated receptor gamma modulator that promotes adipogenesis.

Feige JN, Gelman L, Rossi D, Zoete V, Métivier R, Tudor C, Anghel SI, Grosdidier A, Lathion C, Engelborghs Y, Michielin O, Wahli W, Desvergne B. Feige JN, et al. Among authors: wahli w. J Biol Chem. 2007 Jun 29;282(26):19152-66. doi: 10.1074/jbc.M702724200. Epub 2007 Apr 27. J Biol Chem. 2007. PMID: 17468099 Free article.

118

Expression of the peroxisome proliferator-activated receptor alpha gene is stimulated by stress and follows a diurnal rhythm.

Lemberger T, Saladin R, Vázquez M, Assimacopoulos F, Staels B, Desvergne B, Wahli W, Auwerx J. Lemberger T, et al. Among authors: wahli w. J Biol Chem. 1996 Jan 19;271(3):1764-9. doi: 10.1074/jbc.271.3.1764. J Biol Chem. 1996. PMID: 8576180 Free article.

119

Integrating nuclear receptor mobility in models of gene regulation.

Gelman L, Feige JN, Tudor C, Engelborghs Y, Wahli W, Desvergne B. Gelman L, et al. Among authors: wahli w. Nucl Recept Signal. 2006;4:e010. doi: 10.1621/nrs.04010. Epub 2006 Apr 28. Nucl Recept Signal. 2006. PMID: 16741568 Free PMC article.

120

Sex differences in nuclear receptor-regulated liver metabolic pathways.

Rando G, Wahli W. Rando G, et al. Among authors: wahli w. Biochim Biophys Acta. 2011 Aug;1812(8):964-73. doi: 10.1016/j.bbadis.2010.12.023. Epub 2011 Jan 4. Biochim Biophys Acta. 2011. PMID: 21211563 Free article.

121

PPAR-β/δ activation promotes phospholipid transfer protein expression.

Chehaibi K, Cedó L, Metso J, Palomer X, Santos D, Quesada H, Naceur Slimane M, Wahli W, Julve J, Vázquez-Carrera M, Jauhiainen M, Blanco-Vaca F, Escolà-Gil JC. Chehaibi K, et al. Among authors: wahli w. Biochem Pharmacol. 2015 Mar 15;94(2):101-8. doi: 10.1016/j.bcp.2015.01.016. Epub 2015 Feb 7. Biochem Pharmacol. 2015. PMID: 25662586

122

The selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) paradigm: conceptual framework and therapeutic potential : A consensus statement from the International Atherosclerosis Society (IAS) and the Residual Risk Reduction Initiative (R3i) Foundation.

Fruchart JC, Santos RD, Aguilar-Salinas C, Aikawa M, Al Rasadi K, Amarenco P, Barter PJ, Ceska R, Corsini A, Després JP, Duriez P, Eckel RH, Ezhov MV, Farnier M, Ginsberg HN, Hermans MP, Ishibashi S, Karpe F, Kodama T, Koenig W, Krempf M, Lim S, Lorenzatti AJ, McPherson R, Nuñez-Cortes JM, Nordestgaard BG, Ogawa H, Packard CJ, Plutzky J, Ponte-Negretti CI, Pradhan A, Ray KK, Reiner Ž, Ridker PM, Ruscica M, Sadikot S, Shimano H, Sritara P, Stock JK, Su TC, Susekov AV, Tartar A, Taskinen MR, Tenenbaum A, Tokgözoğlu LS, Tomlinson B, Tybjærg-Hansen A, Valensi P, Vrablík M, Wahli W, Watts GF, Yamashita S, Yokote K, Zambon A, Libby P. Fruchart JC, et al. Among authors: wahli w. Cardiovasc Diabetol. 2019 Jun 4;18(1):71. doi: 10.1186/s12933-019-0864-7. Cardiovasc Diabetol. 2019. PMID: 31164165 Free PMC article. Review.

123

Inactivation of PPARβ/δ adversely affects satellite cells and reduces postnatal myogenesis.

Chandrashekar P, Manickam R, Ge X, Bonala S, McFarlane C, Sharma M, Wahli W, Kambadur R. Chandrashekar P, et al. Among authors: wahli w. Am J Physiol Endocrinol Metab. 2015 Jul 15;309(2):E122-31. doi: 10.1152/ajpendo.00586.2014. Epub 2015 Apr 28. Am J Physiol Endocrinol Metab. 2015. PMID: 25921579 Free article.

Recently, our laboratory showed (Bonala S, Lokireddy S, Arigela H, Teng S, Wahli W, Sharma M, McFarlane C, Kambadur R. J Biol Chem 287: 12935-12951, 2012) that PPARbeta/delta modulates myostatin activity to induce myogenesis in skeletal muscle. ...Previously, our la …

Recently, our laboratory showed (Bonala S, Lokireddy S, Arigela H, Teng S, Wahli W, Sharma M, McFarlane C, Kambadur R. J Biol …

124

From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions.

Feige JN, Gelman L, Michalik L, Desvergne B, Wahli W. Feige JN, et al. Among authors: wahli w. Prog Lipid Res. 2006 Mar;45(2):120-59. doi: 10.1016/j.plipres.2005.12.002. Epub 2006 Jan 25. Prog Lipid Res. 2006. PMID: 16476485 Review.

125

Fat poetry: a kingdom for PPAR gamma.

Anghel SI, Wahli W. Anghel SI, et al. Among authors: wahli w. Cell Res. 2007 Jun;17(6):486-511. doi: 10.1038/cr.2007.48. Cell Res. 2007. PMID: 17563755 Review.

126

Loss of egg yolk genes in mammals and the origin of lactation and placentation.

Brawand D, Wahli W, Kaessmann H. Brawand D, et al. Among authors: wahli w. PLoS Biol. 2008 Mar 18;6(3):e63. doi: 10.1371/journal.pbio.0060063. PLoS Biol. 2008. PMID: 18351802 Free PMC article.

127

PPAR expression and function during vertebrate development.

Michalik L, Desvergne B, Dreyer C, Gavillet M, Laurini RN, Wahli W. Michalik L, et al. Among authors: wahli w. Int J Dev Biol. 2002 Jan;46(1):105-14. Int J Dev Biol. 2002. PMID: 11902671 Review.

128

Intestinal PPARγ signalling is required for sympathetic nervous system activation in response to caloric restriction.

Duszka K, Picard A, Ellero-Simatos S, Chen J, Defernez M, Paramalingam E, Pigram A, Vanoaica L, Canlet C, Parini P, Narbad A, Guillou H, Thorens B, Wahli W. Duszka K, et al. Among authors: wahli w. Sci Rep. 2016 Nov 17;6:36937. doi: 10.1038/srep36937. Sci Rep. 2016. PMID: 27853235 Free PMC article.

129

A proline-rich TGF-beta-responsive transcriptional activator interacts with histone H3.

Alevizopoulos A, Dusserre Y, Tsai-Pflugfelder M, von der Weid T, Wahli W, Mermod N. Alevizopoulos A, et al. Among authors: wahli w. Genes Dev. 1995 Dec 15;9(24):3051-66. doi: 10.1101/gad.9.24.3051. Genes Dev. 1995. PMID: 8543151 Free article.

130

Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting.

Kersten S, Seydoux J, Peters JM, Gonzalez FJ, Desvergne B, Wahli W. Kersten S, et al. Among authors: wahli w. J Clin Invest. 1999 Jun;103(11):1489-98. doi: 10.1172/JCI6223. J Clin Invest. 1999. PMID: 10359558 Free PMC article.

131

Peroxisome proliferator-activated receptors: nuclear control of metabolism.

Desvergne B, Wahli W. Desvergne B, et al. Among authors: wahli w. Endocr Rev. 1999 Oct;20(5):649-88. doi: 10.1210/edrv.20.5.0380. Endocr Rev. 1999. PMID: 10529898 Review. No abstract available.

132

Peroxisome proliferator-activated receptors: three isotypes for a multitude of functions.

Michalik L, Wahli W. Michalik L, et al. Among authors: wahli w. Curr Opin Biotechnol. 1999 Dec;10(6):564-70. doi: 10.1016/s0958-1669(99)00030-0. Curr Opin Biotechnol. 1999. PMID: 10600688 Review.

133

Estrogenic activity assessment of environmental chemicals using in vitro assays: identification of two new estrogenic compounds.

Lascombe I, Beffa D, Rüegg U, Tarradellas J, Wahli W. Lascombe I, et al. Among authors: wahli w. Environ Health Perspect. 2000 Jul;108(7):621-9. doi: 10.1289/ehp.00108621. Environ Health Perspect. 2000. PMID: 10903615 Free PMC article.

134

PPARs: transcriptional effectors of fatty acids and their derivatives.

Hihi AK, Michalik L, Wahli W. Hihi AK, et al. Among authors: wahli w. Cell Mol Life Sci. 2002 May;59(5):790-8. doi: 10.1007/s00018-002-8467-x. Cell Mol Life Sci. 2002. PMID: 12088279 Free PMC article. Review.

135

Kinase signaling cascades that modulate peroxisome proliferator-activated receptors.

Gelman L, Michalik L, Desvergne B, Wahli W. Gelman L, et al. Among authors: wahli w. Curr Opin Cell Biol. 2005 Apr;17(2):216-22. doi: 10.1016/j.ceb.2005.02.002. Curr Opin Cell Biol. 2005. PMID: 15780600 Review.

136

International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors.

Michalik L, Auwerx J, Berger JP, Chatterjee VK, Glass CK, Gonzalez FJ, Grimaldi PA, Kadowaki T, Lazar MA, O'Rahilly S, Palmer CN, Plutzky J, Reddy JK, Spiegelman BM, Staels B, Wahli W. Michalik L, et al. Among authors: wahli w. Pharmacol Rev. 2006 Dec;58(4):726-41. doi: 10.1124/pr.58.4.5. Pharmacol Rev. 2006. PMID: 17132851 Review.

137

PPARs Mediate Lipid Signaling in Inflammation and Cancer.

Michalik L, Wahli W. Michalik L, et al. Among authors: wahli w. PPAR Res. 2008;2008:134059. doi: 10.1155/2008/134059. Epub 2008 Dec 21. PPAR Res. 2008. PMID: 19125181 Free PMC article.

138

Fatty acid synthesis and PPARalpha hand in hand.

Rotman N, Wahli W. Rotman N, et al. Among authors: wahli w. Chem Biol. 2009 Aug 28;16(8):801-2. doi: 10.1016/j.chembiol.2009.08.004. Chem Biol. 2009. PMID: 19716470

139

Role of the circadian clock gene Per2 in adaptation to cold temperature.

Chappuis S, Ripperger JA, Schnell A, Rando G, Jud C, Wahli W, Albrecht U. Chappuis S, et al. Among authors: wahli w. Mol Metab. 2013 May 10;2(3):184-93. doi: 10.1016/j.molmet.2013.05.002. eCollection 2013. Mol Metab. 2013. PMID: 24049733 Free PMC article.

140

High-fat diet modifies the PPAR-γ pathway leading to disruption of microbial and physiological ecosystem in murine small intestine.

Tomas J, Mulet C, Saffarian A, Cavin JB, Ducroc R, Regnault B, Kun Tan C, Duszka K, Burcelin R, Wahli W, Sansonetti PJ, Pédron T. Tomas J, et al. Among authors: wahli w. Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):E5934-E5943. doi: 10.1073/pnas.1612559113. Epub 2016 Sep 16. Proc Natl Acad Sci U S A. 2016. PMID: 27638207 Free PMC article.

141

Mechanistic definition of the cardiovascular mPGES-1/COX-2/ADMA axis.

Kirkby NS, Raouf J, Ahmetaj-Shala B, Liu B, Mazi SI, Edin ML, Chambers MG, Korotkova M, Wang X, Wahli W, Zeldin DC, Nüsing R, Zhou Y, Jakobsson PJ, Mitchell JA. Kirkby NS, et al. Among authors: wahli w. Cardiovasc Res. 2020 Oct 1;116(12):1972-1980. doi: 10.1093/cvr/cvz290. Cardiovasc Res. 2020. PMID: 31688905 Free PMC article.

142

PPARs: nuclear receptors for fatty acids, eicosanoids, and xenobiotics.

Devchand PR, Ijpenberg A, Devesvergne B, Wahli W. Devchand PR, et al. Among authors: wahli w. Adv Exp Med Biol. 1999;469:231-6. doi: 10.1007/978-1-4615-4793-8_34. Adv Exp Med Biol. 1999. PMID: 10667335

143

Transcriptional regulation of metabolism.

Desvergne B, Michalik L, Wahli W. Desvergne B, et al. Among authors: wahli w. Physiol Rev. 2006 Apr;86(2):465-514. doi: 10.1152/physrev.00025.2005. Physiol Rev. 2006. PMID: 16601267 Free article. Review.

144

PPARβ/δ ameliorates fructose-induced insulin resistance in adipocytes by preventing Nrf2 activation.

Barroso E, Rodríguez-Rodríguez R, Chacón MR, Maymó-Masip E, Ferrer L, Salvadó L, Salmerón E, Wabistch M, Palomer X, Vendrell J, Wahli W, Vázquez-Carrera M. Barroso E, et al. Among authors: wahli w. Biochim Biophys Acta. 2015 May;1852(5):1049-58. doi: 10.1016/j.bbadis.2015.02.010. Epub 2015 Feb 26. Biochim Biophys Acta. 2015. PMID: 25728706 Free article.

145

A new selective peroxisome proliferator-activated receptor gamma antagonist with antiobesity and antidiabetic activity.

Rieusset J, Touri F, Michalik L, Escher P, Desvergne B, Niesor E, Wahli W. Rieusset J, et al. Among authors: wahli w. Mol Endocrinol. 2002 Nov;16(11):2628-44. doi: 10.1210/me.2002-0036. Mol Endocrinol. 2002. PMID: 12403851

146

PixFRET, an ImageJ plug-in for FRET calculation that can accommodate variations in spectral bleed-throughs.

Feige JN, Sage D, Wahli W, Desvergne B, Gelman L. Feige JN, et al. Among authors: wahli w. Microsc Res Tech. 2005 Sep;68(1):51-8. doi: 10.1002/jemt.20215. Microsc Res Tech. 2005. PMID: 16208719 Free article.

147

PPARs as drug targets to modulate inflammatory responses?

Genolet R, Wahli W, Michalik L. Genolet R, et al. Among authors: wahli w. Curr Drug Targets Inflamm Allergy. 2004 Dec;3(4):361-75. doi: 10.2174/1568010042634578. Curr Drug Targets Inflamm Allergy. 2004. PMID: 15584886 Review.

148

A gut feeling of the PXR, PPAR and NF-kappaB connection.

Wahli W. Wahli W. J Intern Med. 2008 Jun;263(6):613-9. doi: 10.1111/j.1365-2796.2008.01951.x. J Intern Med. 2008. PMID: 18479261 Free article. Review.

149

Sumoylated PPARalpha mediates sex-specific gene repression and protects the liver from estrogen-induced toxicity in mice.

Leuenberger N, Pradervand S, Wahli W. Leuenberger N, et al. Among authors: wahli w. J Clin Invest. 2009 Oct;119(10):3138-48. doi: 10.1172/JCI39019. J Clin Invest. 2009. PMID: 19729835 Free PMC article.

150

Myostatin augments muscle-specific ring finger protein-1 expression through an NF-kB independent mechanism in SMAD3 null muscle.

Sriram S, Subramanian S, Juvvuna PK, Ge X, Lokireddy S, McFarlane CD, Wahli W, Kambadur R, Sharma M. Sriram S, et al. Among authors: wahli w. Mol Endocrinol. 2014 Mar;28(3):317-30. doi: 10.1210/me.2013-1179. Epub 2014 Jan 17. Mol Endocrinol. 2014. PMID: 24438338 Free PMC article.

151

Multifaceted roles of peroxisome proliferator-activated receptors (PPARs) at the cellular and whole organism levels.

Yessoufou A, Wahli W. Yessoufou A, et al. Among authors: wahli w. Swiss Med Wkly. 2010 Sep 15;140:w13071. doi: 10.4414/smw.2010.13071. eCollection 2010. Swiss Med Wkly. 2010. PMID: 20842602 Free article. Review.

152

GW501516-activated PPARβ/δ promotes liver fibrosis via p38-JNK MAPK-induced hepatic stellate cell proliferation.

Kostadinova R, Montagner A, Gouranton E, Fleury S, Guillou H, Dombrowicz D, Desreumaux P, Wahli W. Kostadinova R, et al. Among authors: wahli w. Cell Biosci. 2012 Oct 10;2(1):34. doi: 10.1186/2045-3701-2-34. Cell Biosci. 2012. PMID: 23046570 Free PMC article.

153

Guiding ligands to nuclear receptors.

Michalik L, Wahli W. Michalik L, et al. Among authors: wahli w. Cell. 2007 May 18;129(4):649-51. doi: 10.1016/j.cell.2007.05.001. Cell. 2007. PMID: 17512397 Free article. Review.

154

Differential expression of peroxisome proliferator-activated receptor-alpha, -beta, and -gamma during rat embryonic development.

Braissant O, Wahli W. Braissant O, et al. Among authors: wahli w. Endocrinology. 1998 Jun;139(6):2748-54. doi: 10.1210/endo.139.6.6049. Endocrinology. 1998. PMID: 9607781

155

PPAR alpha structure-function relationships derived from species-specific differences in responsiveness to hypolipidemic agents.

Keller H, Devchand PR, Perroud M, Wahli W. Keller H, et al. Among authors: wahli w. Biol Chem. 1997 Jul;378(7):651-5. doi: 10.1515/bchm.1997.378.7.651. Biol Chem. 1997. PMID: 9278144

156

Transcriptional repression of peroxisome proliferator-activated receptor beta/delta in murine keratinocytes by CCAAT/enhancer-binding proteins.

Di-Poï N, Desvergne B, Michalik L, Wahli W. Di-Poï N, et al. Among authors: wahli w. J Biol Chem. 2005 Nov 18;280(46):38700-10. doi: 10.1074/jbc.M507782200. Epub 2005 Sep 15. J Biol Chem. 2005. PMID: 16166081 Free article.

157

Mechanisms of the anti-obesity effects of oxytocin in diet-induced obese rats.

Deblon N, Veyrat-Durebex C, Bourgoin L, Caillon A, Bussier AL, Petrosino S, Piscitelli F, Legros JJ, Geenen V, Foti M, Wahli W, Di Marzo V, Rohner-Jeanrenaud F. Deblon N, et al. Among authors: wahli w. PLoS One. 2011;6(9):e25565. doi: 10.1371/journal.pone.0025565. Epub 2011 Sep 27. PLoS One. 2011. PMID: 21980491 Free PMC article.

158

Peroxisome proliferator activated receptor agonists.

Kersten S, Wahli W. Kersten S, et al. Among authors: wahli w. EXS. 2000;89:141-51. doi: 10.1007/978-3-0348-8393-1_9. EXS. 2000. PMID: 10997287 Review.

159

Regional variations in ABC transporter expression along the mouse intestinal tract.

Mutch DM, Anderle P, Fiaux M, Mansourian R, Vidal K, Wahli W, Williamson G, Roberts MA. Mutch DM, et al. Among authors: wahli w. Physiol Genomics. 2004 Mar 12;17(1):11-20. doi: 10.1152/physiolgenomics.00150.2003. Physiol Genomics. 2004. PMID: 14679303

160

Rat PPARs: quantitative analysis in adult rat tissues and regulation in fasting and refeeding.

Escher P, Braissant O, Basu-Modak S, Michalik L, Wahli W, Desvergne B. Escher P, et al. Among authors: wahli w. Endocrinology. 2001 Oct;142(10):4195-202. doi: 10.1210/endo.142.10.8458. Endocrinology. 2001. PMID: 11564675

161

Functional interactions of peroxisome proliferator-activated receptor, retinoid-X receptor, and Sp1 in the transcriptional regulation of the acyl-coenzyme-A oxidase promoter.

Krey G, Mahfoudi A, Wahli W. Krey G, et al. Among authors: wahli w. Mol Endocrinol. 1995 Feb;9(2):219-31. doi: 10.1210/mend.9.2.7776972. Mol Endocrinol. 1995. PMID: 7776972

162

Peroxisome proliferator-activated receptors and lipid metabolism.

Keller H, Mahfoudi A, Dreyer C, Hihi AK, Medin J, Ozato K, Wahli W. Keller H, et al. Among authors: wahli w. Ann N Y Acad Sci. 1993 Jun 11;684:157-73. doi: 10.1111/j.1749-6632.1993.tb32279.x. Ann N Y Acad Sci. 1993. PMID: 8391237 Review.

163

Involvement of PPAR nuclear receptors in tissue injury and wound repair.

Michalik L, Wahli W. Michalik L, et al. Among authors: wahli w. J Clin Invest. 2006 Mar;116(3):598-606. doi: 10.1172/JCI27958. J Clin Invest. 2006. PMID: 16511592 Free PMC article. Review.

164

The emerging role of PPARs in primary biliary cholangitis.

Palomer X, Rodríguez-Calvo R, García-Mateo S, Wahli W, Vázquez-Carrera M. Palomer X, et al. Among authors: wahli w. Trends Mol Med. 2026 Jun 13:S1471-4914(26)00133-4. doi: 10.1016/j.molmed.2026.05.008. Online ahead of print. Trends Mol Med. 2026. PMID: 42285879 Review.

165

Palmitic and oleic acids in type 2 diabetes mellitus.

Palomer X, Rodríguez-Calvo R, Tajes M, Wahli W, Vázquez-Carrera M. Palomer X, et al. Among authors: wahli w. Trends Endocrinol Metab. 2026 Mar 30:S1043-2760(26)00003-2. doi: 10.1016/j.tem.2026.01.003. Online ahead of print. Trends Endocrinol Metab. 2026. PMID: 41912364 Review.

166

PPARβ/δ contributes to the antidiabetic effect and the increase in GDF15 caused by metformin.

Jurado-Aguilar J, Barroso E, Rada P, Peyman M, Rostami A, Balsinde J, Valverde ÁM, Wahli W, Palomer X, Vázquez-Carrera M. Jurado-Aguilar J, et al. Among authors: wahli w. Acta Pharmacol Sin. 2026 May;47(5):1219-1232. doi: 10.1038/s41401-025-01705-5. Epub 2026 Jan 16. Acta Pharmacol Sin. 2026. PMID: 41545750

167

Targeting AMPK as a potential treatment for hepatic fibrosis in MASLD.

Palomer X, Wang JR, Escalona C, Wu S, Wahli W, Vázquez-Carrera M. Palomer X, et al. Among authors: wahli w. Trends Pharmacol Sci. 2025 Jun;46(6):551-566. doi: 10.1016/j.tips.2025.03.008. Epub 2025 Apr 28. Trends Pharmacol Sci. 2025. PMID: 40300935 Review.

168

Palmitate potentiates the SMAD3-PAI-1 pathway by reducing nuclear GDF15 levels.

Montori-Grau M, Barroso E, Jurado-Aguilar J, Peyman M, Wahli W, Palomer X, Vázquez-Carrera M. Montori-Grau M, et al. Among authors: wahli w. Cell Mol Life Sci. 2025 Jan 18;82(1):43. doi: 10.1007/s00018-024-05571-y. Cell Mol Life Sci. 2025. PMID: 39825925 Free PMC article.

169

PPARβ/δ upregulates the insulin receptor β subunit in skeletal muscle by reducing lysosomal activity and EphB4 levels.

Wang JR, Jurado-Aguilar J, Barroso E, Rodríguez-Calvo R, Camins A, Wahli W, Palomer X, Vázquez-Carrera M. Wang JR, et al. Among authors: wahli w. Cell Commun Signal. 2024 Dec 18;22(1):595. doi: 10.1186/s12964-024-01972-5. Cell Commun Signal. 2024. PMID: 39696437 Free PMC article.

170

PPARβ/δ prevents inflammation and fibrosis during diabetic cardiomyopathy.

Rostami A, Palomer X, Pizarro-Delgado J, Barroso E, Valenzuela-Alcaraz B, Crispi F, Nistal JF, Hurlé MA, García R, Wahli W, Vázquez-Carrera M. Rostami A, et al. Among authors: wahli w. Pharmacol Res. 2024 Dec;210:107515. doi: 10.1016/j.phrs.2024.107515. Epub 2024 Nov 20. Pharmacol Res. 2024. PMID: 39577755 Free article.

171

Lipid sensing by PPARα: Role in controlling hepatocyte gene regulatory networks and the metabolic response to fasting.

Fougerat A, Bruse J, Polizzi A, Montagner A, Guillou H, Wahli W. Fougerat A, et al. Among authors: wahli w. Prog Lipid Res. 2024 Nov;96:101303. doi: 10.1016/j.plipres.2024.101303. Epub 2024 Nov 7. Prog Lipid Res. 2024. PMID: 39521352 Free article. Review.

172

PPARβ/δ attenuates hepatic fibrosis by reducing SMAD3 phosphorylation and p300 levels via AMPK in hepatic stellate cells.

Zhang M, Barroso E, Peña L, Rada P, Valverde ÁM, Wahli W, Palomer X, Vázquez-Carrera M. Zhang M, et al. Among authors: wahli w. Biomed Pharmacother. 2024 Oct;179:117303. doi: 10.1016/j.biopha.2024.117303. Epub 2024 Aug 18. Biomed Pharmacother. 2024. PMID: 39153437 Free article.

173

The LIDPAD Mouse Model Captures the Multisystem Interactions and Extrahepatic Complications in MASLD.

Low ZS, Chua D, Cheng HS, Tee R, Tan WR, Ball C, Sahib NBE, Ng SS, Qu J, Liu Y, Hong H, Cai C, Rao NCL, Wee A, Muthiah MD, Bichler Z, Mickelson B, Kong MS, Tay VS, Yan Z, Chen J, Ng AS, Yip YS, Vos MIG, Tan NA, Lim DL, Lim DXE, Chittezhath M, Yaligar J, Verma SK, Poptani H, Guan XL, Velan SS, Ali Y, Li L, Tan NS, Wahli W. Low ZS, et al. Among authors: wahli w. Adv Sci (Weinh). 2024 Sep;11(35):e2404326. doi: 10.1002/advs.202404326. Epub 2024 Jul 1. Adv Sci (Weinh). 2024. PMID: 38952069 Free PMC article.

174

Increased hepatic gluconeogenesis and type 2 diabetes mellitus.

Barroso E, Jurado-Aguilar J, Wahli W, Palomer X, Vázquez-Carrera M. Barroso E, et al. Among authors: wahli w. Trends Endocrinol Metab. 2024 Dec;35(12):1062-1077. doi: 10.1016/j.tem.2024.05.006. Epub 2024 May 29. Trends Endocrinol Metab. 2024. PMID: 38816269 Review.

175

GDF15 activates AMPK and inhibits gluconeogenesis and fibrosis in the liver by attenuating the TGF-β1/SMAD3 pathway.

Jurado-Aguilar J, Barroso E, Bernard M, Zhang M, Peyman M, Rada P, Valverde ÁM, Wahli W, Palomer X, Vázquez-Carrera M. Jurado-Aguilar J, et al. Among authors: wahli w. Metabolism. 2024 Mar;152:155772. doi: 10.1016/j.metabol.2023.155772. Epub 2024 Jan 3. Metabolism. 2024. PMID: 38176644 Free article.

176

Elafibranor upregulates the EMT-inducer S100A4 via PPARβ/δ.

Zhang M, Barroso E, Ruart M, Peña L, Peyman M, Aguilar-Recarte D, Montori-Grau M, Rada P, Cugat C, Montironi C, Zarei M, Jurado-Aguilar J, Camins A, Balsinde J, Valverde ÁM, Wahli W, Palomer X, Vázquez-Carrera M. Zhang M, et al. Among authors: wahli w. Biomed Pharmacother. 2023 Nov;167:115623. doi: 10.1016/j.biopha.2023.115623. Epub 2023 Sep 30. Biomed Pharmacother. 2023. PMID: 37783154 Free article.

177

Striking a gut-liver balance for the antidiabetic effects of metformin.

Barroso E, Montori-Grau M, Wahli W, Palomer X, Vázquez-Carrera M. Barroso E, et al. Among authors: wahli w. Trends Pharmacol Sci. 2023 Jul;44(7):457-473. doi: 10.1016/j.tips.2023.04.004. Epub 2023 May 13. Trends Pharmacol Sci. 2023. PMID: 37188578 Review.

178

A positive feedback loop between AMPK and GDF15 promotes metformin antidiabetic effects.

Aguilar-Recarte D, Barroso E, Zhang M, Rada P, Pizarro-Delgado J, Peña L, Palomer X, Valverde ÁM, Wahli W, Vázquez-Carrera M. Aguilar-Recarte D, et al. Among authors: wahli w. Pharmacol Res. 2023 Jan;187:106578. doi: 10.1016/j.phrs.2022.106578. Epub 2022 Nov 23. Pharmacol Res. 2023. PMID: 36435271 Free article.

179

Author Correction: EMPReSS: standardized phenotype screens for functional annotation of the mouse genome.

Eumorphia Consortium. Eumorphia Consortium. Nat Genet. 2022 Mar;54(3):358-360. doi: 10.1038/s41588-022-01019-w. Nat Genet. 2022. PMID: 35169327 No abstract available.

180

Residual vascular risk in diabetes - Will the SPPARM alpha concept hold the key?

Fruchart JC, Santos RD, Yamashita S, Libby P; International Atherosclerosis Society/R3i Foundation Consensus Panel. Fruchart JC, et al. Diabetes Metab Syndr. 2019 Jul-Aug;13(4):2723-2725. doi: 10.1016/j.dsx.2019.05.034. Epub 2019 May 30. Diabetes Metab Syndr. 2019. PMID: 31405699 Free article. Review. No abstract available.

181

Peroxisome proliferator-activated receptor β/δ induces myogenesis by modulating myostatin activity.

Bonala S, Lokireddy S, Arigela H, Teng S, Wahli W, Sharma M, McFarlane C, Kambadur R. Bonala S, et al. Among authors: wahli w. J Biol Chem. 2016 Jul 1;291(27):14391. doi: 10.1074/jbc.A111.319145. J Biol Chem. 2016. PMID: 27371567 Free PMC article. No abstract available.

182

"Every day I dream ..." An interview with the Rwandan Health Minister.

Suter PM, Wahli W. Suter PM, et al. Among authors: wahli w. Swiss Med Wkly. 2016 May 6;146:w14316. doi: 10.4414/smw.2016.14316. eCollection 2016. Swiss Med Wkly. 2016. PMID: 27152723 Free article. No abstract available.

183

Erratum: Hepatic circadian clock oscillators and nuclear receptors integrate microbiome-derived signals.

Montagner A, Korecka A, Polizzi A, Lippi Y, Blum Y, Canlet C, Tremblay-Franco M, Gautier-Stein A, Burcelin R, Yen YC, Je HS, Al-Asmakh M, Mithieux G, Arulampalam V, Lagarrigue S, Guillou H, Pettersson S, Wahli W. Montagner A, et al. Among authors: wahli w. Sci Rep. 2016 Apr 20;6:23951. doi: 10.1038/srep23951. Sci Rep. 2016. PMID: 27094712 Free PMC article. No abstract available.

184

Authorship in scientific publications: analysis and recommendations.

Scientific Integrity Committee of Swiss Academies of Arts And Sciences; Hess CW, Brückner C, Kaiser T, Mauron A, Wahli W, Wenzel UJ, Salathé M. Scientific Integrity Committee of Swiss Academies of Arts And Sciences, et al. Among authors: wahli w. Swiss Med Wkly. 2015 Feb 21;145:w14108. doi: 10.4414/smw.2015.14108. eCollection 2015. Swiss Med Wkly. 2015. PMID: 25701667 Free article.

185

The coactivator PGC-1α regulates skeletal muscle oxidative metabolism independently of the nuclear receptor PPARβ/δ in sedentary mice fed a regular chow diet.

Pérez-Schindler J, Svensson K, Vargas-Fernández E, Santos G, Wahli W, Handschin C. Pérez-Schindler J, et al. Among authors: wahli w. Diabetologia. 2014 Nov;57(11):2405-12. doi: 10.1007/s00125-014-3352-3. Epub 2014 Aug 13. Diabetologia. 2014. PMID: 25116175 Free PMC article.

186

PPARβ/δ prevents endoplasmic reticulum stress-associated inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism.

Salvadó L, Barroso E, Gómez-Foix AM, Palomer X, Michalik L, Wahli W, Vázquez-Carrera M. Salvadó L, et al. Among authors: wahli w. Diabetologia. 2014 Oct;57(10):2126-35. doi: 10.1007/s00125-014-3331-8. Epub 2014 Jul 26. Diabetologia. 2014. PMID: 25063273

187

Src is activated by the nuclear receptor peroxisome proliferator-activated receptor β/δ in ultraviolet radiation-induced skin cancer.

Montagner A, Delgado MB, Tallichet-Blanc C, Chan JS, Sng MK, Mottaz H, Degueurce G, Lippi Y, Moret C, Baruchet M, Antsiferova M, Werner S, Hohl D, Saati TA, Farmer PJ, Tan NS, Michalik L, Wahli W. Montagner A, et al. Among authors: wahli w. EMBO Mol Med. 2014 Jan;6(1):80-98. doi: 10.1002/emmm.201302666. EMBO Mol Med. 2014. PMID: 24203162 Free PMC article.

188

Tau hyperphosphorylation and increased BACE1 and RAGE levels in the cortex of PPARβ/δ-null mice.

Barroso E, del Valle J, Porquet D, Vieira Santos AM, Salvadó L, Rodríguez-Rodríguez R, Gutiérrez P, Anglada-Huguet M, Alberch J, Camins A, Palomer X, Pallàs M, Michalik L, Wahli W, Vázquez-Carrera M. Barroso E, et al. Among authors: wahli w. Biochim Biophys Acta. 2013 Aug;1832(8):1241-8. doi: 10.1016/j.bbadis.2013.03.006. Epub 2013 Mar 16. Biochim Biophys Acta. 2013. PMID: 23507144 Free article.

189

Contributions of peroxisome proliferator-activated receptor β/δ to skin health and disease.

Montagner A, Wahli W. Montagner A, et al. Among authors: wahli w. Biomol Concepts. 2013 Feb;4(1):53-64. doi: 10.1515/bmc-2012-0035. Biomol Concepts. 2013. PMID: 25436565 Review.

190

The peroxisome proliferator-activated receptor (PPAR) β/δ agonist GW501516 inhibits IL-6-induced signal transducer and activator of transcription 3 (STAT3) activation and insulin resistance in human liver cells.

Serrano-Marco L, Barroso E, El Kochairi I, Palomer X, Michalik L, Wahli W, Vázquez-Carrera M. Serrano-Marco L, et al. Among authors: wahli w. Diabetologia. 2012 Mar;55(3):743-51. doi: 10.1007/s00125-011-2401-4. Epub 2011 Dec 17. Diabetologia. 2012. PMID: 22179221

191

The inhibition of fat cell proliferation by n-3 fatty acids in dietary obese mice.

Hensler M, Bardova K, Jilkova ZM, Wahli W, Meztger D, Chambon P, Kopecky J, Flachs P. Hensler M, et al. Among authors: wahli w. Lipids Health Dis. 2011 Aug 2;10:128. doi: 10.1186/1476-511X-10-128. Lipids Health Dis. 2011. PMID: 21810216 Free PMC article.

192

Activation of peroxisome proliferator-activated receptor-β/-δ (PPAR-β/-δ) ameliorates insulin signaling and reduces SOCS3 levels by inhibiting STAT3 in interleukin-6-stimulated adipocytes.

Serrano-Marco L, Rodríguez-Calvo R, El Kochairi I, Palomer X, Michalik L, Wahli W, Vázquez-Carrera M. Serrano-Marco L, et al. Among authors: wahli w. Diabetes. 2011 Jul;60(7):1990-9. doi: 10.2337/db10-0704. Epub 2011 May 26. Diabetes. 2011. PMID: 21617181 Free PMC article.

193

Hepatic deficiency in transcriptional cofactor TBL1 promotes liver steatosis and hypertriglyceridemia.

Kulozik P, Jones A, Mattijssen F, Rose AJ, Reimann A, Strzoda D, Kleinsorg S, Raupp C, Kleinschmidt J, Müller-Decker K, Wahli W, Sticht C, Gretz N, von Loeffelholz C, Stockmann M, Pfeiffer A, Stöhr S, Dallinga-Thie GM, Nawroth PP, Diaz MB, Herzig S. Kulozik P, et al. Among authors: wahli w. Cell Metab. 2011 Apr 6;13(4):389-400. doi: 10.1016/j.cmet.2011.02.011. Cell Metab. 2011. PMID: 21459324 Free article.

194

Proline- and acidic amino acid-rich basic leucine zipper proteins modulate peroxisome proliferator-activated receptor alpha (PPARalpha) activity.

Gachon F, Leuenberger N, Claudel T, Gos P, Jouffe C, Fleury Olela F, de Mollerat du Jeu X, Wahli W, Schibler U. Gachon F, et al. Among authors: wahli w. Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):4794-9. doi: 10.1073/pnas.1002862108. Epub 2011 Mar 7. Proc Natl Acad Sci U S A. 2011. PMID: 21383142 Free PMC article.

195

Peroxisome proliferator-activated receptor β/δ: a master regulator of metabolic pathways in skeletal muscle.

Lahiri S, Wahli W. Lahiri S, et al. Among authors: wahli w. Horm Mol Biol Clin Investig. 2010 Dec 1;4(2):565-73. doi: 10.1515/HMBCI.2010.076. Horm Mol Biol Clin Investig. 2010. PMID: 25961233

196

PPARβ/δ activation blocks lipid-induced inflammatory pathways in mouse heart and human cardiac cells.

Alvarez-Guardia D, Palomer X, Coll T, Serrano L, Rodríguez-Calvo R, Davidson MM, Merlos M, El Kochairi I, Michalik L, Wahli W, Vázquez-Carrera M. Alvarez-Guardia D, et al. Among authors: wahli w. Biochim Biophys Acta. 2011 Feb;1811(2):59-67. doi: 10.1016/j.bbalip.2010.11.002. Epub 2010 Nov 9. Biochim Biophys Acta. 2011. PMID: 21070867

197

Cyclooxygenase-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytes.

Vegiopoulos A, Müller-Decker K, Strzoda D, Schmitt I, Chichelnitskiy E, Ostertag A, Berriel Diaz M, Rozman J, Hrabe de Angelis M, Nüsing RM, Meyer CW, Wahli W, Klingenspor M, Herzig S. Vegiopoulos A, et al. Among authors: wahli w. Science. 2010 May 28;328(5982):1158-61. doi: 10.1126/science.1186034. Epub 2010 May 6. Science. 2010. PMID: 20448152

198

EuroPhenome: a repository for high-throughput mouse phenotyping data.

Morgan H, Beck T, Blake A, Gates H, Adams N, Debouzy G, Leblanc S, Lengger C, Maier H, Melvin D, Meziane H, Richardson D, Wells S, White J, Wood J; EUMODIC Consortium; de Angelis MH, Brown SD, Hancock JM, Mallon AM. Morgan H, et al. Nucleic Acids Res. 2010 Jan;38(Database issue):D577-85. doi: 10.1093/nar/gkp1007. Epub 2009 Nov 23. Nucleic Acids Res. 2010. PMID: 19933761 Free PMC article.

199

A concerted kinase interplay identifies PPARgamma as a molecular target of ghrelin signaling in macrophages.

Demers A, Caron V, Rodrigue-Way A, Wahli W, Ong H, Tremblay A. Demers A, et al. Among authors: wahli w. PLoS One. 2009 Nov 4;4(11):e7728. doi: 10.1371/journal.pone.0007728. PLoS One. 2009. PMID: 19888469 Free PMC article.

200

Atherosclerotic mice exhibit systemic inflammation in periadventitial and visceral adipose tissue, liver, and pancreatic islets.

Lohmann C, Schäfer N, von Lukowicz T, Sokrates Stein MA, Borén J, Rütti S, Wahli W, Donath MY, Lüscher TF, Matter CM. Lohmann C, et al. Among authors: wahli w. Atherosclerosis. 2009 Dec;207(2):360-7. doi: 10.1016/j.atherosclerosis.2009.05.004. Epub 2009 May 14. Atherosclerosis. 2009. PMID: 19481752

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