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Page 1
Pediatric pulmonary hypertension: insulin-like growth factor-binding protein 2 is a novel marker associated with disease severity and survival.
Griffiths M, Yang J, Nies M, Vaidya D, Brandal S, Williams M, Matsui EC, Grant T, Damico R, Ivy D, Austin ED, Nichols WC, Pauciulo MW, Lutz K, Rosenzweig EB, Hirsch R, Yung D, Everett AD. Griffiths M, et al. Among authors: yung d. Pediatr Res. 2020 Dec;88(6):850-856. doi: 10.1038/s41390-020-01113-x. Epub 2020 Sep 14. Pediatr Res. 2020. PMID: 32927467 Free PMC article.
Building a dedicated pediatric pulmonary hypertension program: A consensus statement from the pediatric pulmonary hypertension network.
Handler SS, Varghese NP, Rosenzweig EB, Yung D, Krishnan U, Whalen E, Bates A, Avitabile CM, Jackson EO, Hirsch R, Fineman J, Abman SH; Pediatric Pulmonary Hypertension Network (PPHNet). Handler SS, et al. Among authors: yung d. Pulm Circ. 2022 Feb 15;12(1):e12031. doi: 10.1002/pul2.12031. eCollection 2022 Jan. Pulm Circ. 2022. PMID: 35506071 Free PMC article.
Effects of long-term bosentan in children with pulmonary arterial hypertension.
Rosenzweig EB, Ivy DD, Widlitz A, Doran A, Claussen LR, Yung D, Abman SH, Morganti A, Nguyen N, Barst RJ. Rosenzweig EB, et al. Among authors: yung d. J Am Coll Cardiol. 2005 Aug 16;46(4):697-704. doi: 10.1016/j.jacc.2005.01.066. J Am Coll Cardiol. 2005. PMID: 16098438 Free article.
Haemodynamic characterisation and heart catheterisation complications in children with pulmonary hypertension: Insights from the Global TOPP Registry (tracking outcomes and practice in paediatric pulmonary hypertension).
Beghetti M, Schulze-Neick I, Berger RM, Ivy DD, Bonnet D, Weintraub RG, Saji T, Yung D, Mallory GB, Geiger R, Berger JT, Barst RJ, Humpl T; TOPP Investigators. Beghetti M, et al. Among authors: yung d. Int J Cardiol. 2016 Jan 15;203:325-30. doi: 10.1016/j.ijcard.2015.10.087. Epub 2015 Oct 23. Int J Cardiol. 2016. PMID: 26583838
Age-related differences in hemodynamics and functional status in pulmonary arterial hypertension: Baseline results from the Pulmonary Hypertension Association Registry.
DesJardin JT, Kolaitis NA, Kime N, Kronmal RA, Benza RL, Elwing JM, Lammi MR, McConnell JW, Presberg KW, Sager JS, Shlobin OA, De Marco T; PHAR Investigators. DesJardin JT, et al. J Heart Lung Transplant. 2020 Sep;39(9):945-953. doi: 10.1016/j.healun.2020.05.005. Epub 2020 May 16. J Heart Lung Transplant. 2020. PMID: 32507341
Pulmonary-to-Systemic Arterial Shunt to Treat Children With Severe Pulmonary Hypertension.
Grady RM, Canter MW, Wan F, Shmalts AA, Coleman RD, Beghetti M, Berger RMF, Del Cerro Marin MJ, Fletcher SE, Hirsch R, Humpl T, Ivy DD, Kirkpatrick EC, Kulik TJ, Levy M, Moledina S, Yung D, Eghtesady P, Bonnet D; International Registry Potts Shunt. Grady RM, et al. Among authors: yung d. J Am Coll Cardiol. 2021 Aug 3;78(5):468-477. doi: 10.1016/j.jacc.2021.05.039. J Am Coll Cardiol. 2021. PMID: 34325836 Free PMC article.
Angiostatic Peptide, Endostatin, Predicts Severity in Pediatric Congenital Heart Disease-Associated Pulmonary Hypertension.
Daly CM, Griffiths M, Simpson CE, Yang J, Damico RL, Vaidya RD, Williams M, Brandal S, Jone PN, Polsen C, Ivy DD, Austin ED, Nichols WC, Pauciulo MW, Lutz K, Nies MK, Rosenzweig EB, Hirsch R, Yung D, Everett AD. Daly CM, et al. Among authors: yung d. J Am Heart Assoc. 2021 Oct 19;10(20):e021409. doi: 10.1161/JAHA.120.021409. Epub 2021 Oct 8. J Am Heart Assoc. 2021. PMID: 34622662 Free PMC article.
Cardiac Catheterization and Hemodynamics in a Multicenter Cohort of Children with Pulmonary Hypertension.
Rosenzweig EB, Bates A, Mullen MP, Abman SH, Austin ED, Everett A, Fineman J, Feinstein J, Hopper RK, Kinsella JP, Krishnan US, Lu M, Mandl KD, Raj JU, Varghese N, Yung D, Handler SS, Sleeper LA. Rosenzweig EB, et al. Among authors: yung d. Ann Am Thorac Soc. 2022 Jun;19(6):1000-1012. doi: 10.1513/AnnalsATS.202108-998OC. Ann Am Thorac Soc. 2022. PMID: 35049414 Free PMC article.
Biomarkers of Pulmonary Hypertension Are Altered in Children with Down Syndrome and Pulmonary Hypertension.
Griffiths M, Yang J, Vaidya D, Nies M, Brandal S, Ivy DD, Hickey F, Wolter-Warmerdam K, Austin ED, Mullen M, Pauciulo MW, Lutz KA, Rosenzweig EB, Hirsch R, Yung D, Nichols WC, Everett AD. Griffiths M, et al. Among authors: yung d. J Pediatr. 2022 Feb;241:68-76.e3. doi: 10.1016/j.jpeds.2021.10.017. Epub 2021 Oct 21. J Pediatr. 2022. PMID: 34687693 Free PMC article.
Pulmonary Hypertension in Children with Down Syndrome: Results from the Pediatric Pulmonary Hypertension Network Registry.
Hopper RK, Abman SH, Elia EG, Avitabile CM, Yung D, Mullen MP, Austin ED, Bates A, Handler SS, Feinstein JA, Ivy DD, Kinsella JP, Mandl KD, Raj JU, Sleeper LA; Pediatric Pulmonary Hypertension Network Investigators. Hopper RK, et al. Among authors: yung d. J Pediatr. 2023 Jan;252:131-140.e3. doi: 10.1016/j.jpeds.2022.08.027. Epub 2022 Aug 24. J Pediatr. 2023. PMID: 36027975 Free PMC article.
Impact of the COVID-19 pandemic on chronic disease management and patient reported outcomes in patients with pulmonary hypertension: The Pulmonary Hypertension Association Registry.
Mayer M, Badesch DB, Nielsen KH, Kawut S, Bull T, Ryan JJ, Sager J, Mazimba S, Hemnes A, Klinger J, Runo J, McConnell JW, De Marco T, Chakinala MM, Yung D, Elwing J, Kaplan A, Argula R, Pomponio R, Peterson R, Hountras P. Mayer M, et al. Among authors: yung d. Pulm Circ. 2023 Apr 1;13(2):e12233. doi: 10.1002/pul2.12233. eCollection 2023 Apr. Pulm Circ. 2023. PMID: 37159803 Free PMC article.
The Fontan Udenafil Exercise Longitudinal Trial: Subgroup Analysis.
Goldberg DJ, Hu C, Lubert AM, Rathod RH, Penny DJ, Petit CJ, Schumacher KR, Ginde S, Williams RV, Yoon JK, Kim GB, Nowlen TT, DiMaria MV, Frischhertz BP, Wagner JB, McHugh KE, McCrindle BW, Cartoski MJ, Detterich JA, Yetman AT, John AS, Richmond ME, Yung D, Payne RM, Mackie AS, Davis CK, Shahanavaz S, Hill KD, Almaguer M, Zak V, McBride MG, Goldstein BH, Pearson GD, Paridon SM; Pediatric Heart Network Investigators. Goldberg DJ, et al. Among authors: yung d. Pediatr Cardiol. 2023 Dec;44(8):1691-1701. doi: 10.1007/s00246-023-03204-y. Epub 2023 Jun 29. Pediatr Cardiol. 2023. PMID: 37382636 Clinical Trial.
Mining the Plasma Proteome for Insights into the Molecular Pathology of Pulmonary Arterial Hypertension.
Harbaum L, Rhodes CJ, Wharton J, Lawrie A, Karnes JH, Desai AA, Nichols WC, Humbert M, Montani D, Girerd B, Sitbon O, Boehm M, Novoyatleva T, Schermuly RT, Ghofrani HA, Toshner M, Kiely DG, Howard LS, Swietlik EM, Gräf S, Pietzner M, Morrell NW, Wilkins MR; U.K. National Institute for Health Research BioResource Rare Diseases Consortium, U.K. Pulmonary Arterial Hypertension Cohort Study Consortium, and U.S. Pulmonary Arterial Hypertension Biobank Consortium. Harbaum L, et al. Am J Respir Crit Care Med. 2022 Jun 15;205(12):1449-1460. doi: 10.1164/rccm.202109-2106OC. Am J Respir Crit Care Med. 2022. PMID: 35394406 Free PMC article.
Prediction of Health-related Quality of Life and Hospitalization in Pulmonary Arterial Hypertension: The Pulmonary Hypertension Association Registry.
Min J, Badesch D, Chakinala M, Elwing J, Frantz R, Horn E, Klinger J, Lammi M, Mazimba S, Sager J, Shlobin O, Simon M, Thenappan T, Grinnan D, Ventetuolo C, Al-Naamani N; PHAR Investigators. Min J, et al. Am J Respir Crit Care Med. 2021 Mar 15;203(6):761-764. doi: 10.1164/rccm.202010-3967LE. Am J Respir Crit Care Med. 2021. PMID: 33211974 Free PMC article. No abstract available.
Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.
Rhodes CJ, Batai K, Bleda M, Haimel M, Southgate L, Germain M, Pauciulo MW, Hadinnapola C, Aman J, Girerd B, Arora A, Knight J, Hanscombe KB, Karnes JH, Kaakinen M, Gall H, Ulrich A, Harbaum L, Cebola I, Ferrer J, Lutz K, Swietlik EM, Ahmad F, Amouyel P, Archer SL, Argula R, Austin ED, Badesch D, Bakshi S, Barnett C, Benza R, Bhatt N, Bogaard HJ, Burger CD, Chakinala M, Church C, Coghlan JG, Condliffe R, Corris PA, Danesino C, Debette S, Elliott CG, Elwing J, Eyries M, Fortin T, Franke A, Frantz RP, Frost A, Garcia JGN, Ghio S, Ghofrani HA, Gibbs JSR, Harley J, He H, Hill NS, Hirsch R, Houweling AC, Howard LS, Ivy D, Kiely DG, Klinger J, Kovacs G, Lahm T, Laudes M, Machado RD, MacKenzie Ross RV, Marsolo K, Martin LJ, Moledina S, Montani D, Nathan SD, Newnham M, Olschewski A, Olschewski H, Oudiz RJ, Ouwehand WH, Peacock AJ, Pepke-Zaba J, Rehman Z, Robbins I, Roden DM, Rosenzweig EB, Saydain G, Scelsi L, Schilz R, Seeger W, Shaffer CM, Simms RW, Simon M, Sitbon O, Suntharalingam J, Tang H, Tchourbanov AY, Thenappan T, Torres F, Toshner MR, Treacy CM, Vonk Noordegraaf A, Waisfisz Q, Walsworth AK, Walter RE, Wharton J, White RJ, Wilt J, Wort SJ, Yung D, Lawrie A, Humbert M, Sou… See abstract for full author list ➔ Rhodes CJ, et al. Among authors: yung d. Lancet Respir Med. 2019 Mar;7(3):227-238. doi: 10.1016/S2213-2600(18)30409-0. Epub 2018 Dec 5. Lancet Respir Med. 2019. PMID: 30527956 Free PMC article.
Rare variant analysis of 4241 pulmonary arterial hypertension cases from an international consortium implicates FBLN2, PDGFD, and rare de novo variants in PAH.
Zhu N, Swietlik EM, Welch CL, Pauciulo MW, Hagen JJ, Zhou X, Guo Y, Karten J, Pandya D, Tilly T, Lutz KA, Martin JM, Treacy CM, Rosenzweig EB, Krishnan U, Coleman AW, Gonzaga-Jauregui C, Lawrie A, Trembath RC, Wilkins MR; Regeneron Genetics Center; PAH Biobank Enrolling Centers’ Investigators; NIHR BioResource for Translational Research - Rare Diseases; National Cohort Study of Idiopathic and Heritable PAH; Morrell NW, Shen Y, Gräf S, Nichols WC, Chung WK. Zhu N, et al. Genome Med. 2021 May 10;13(1):80. doi: 10.1186/s13073-021-00891-1. Genome Med. 2021. PMID: 33971972 Free PMC article.
A study of aspirin and clopidogrel in idiopathic pulmonary arterial hypertension.
Robbins IM, Kawut SM, Yung D, Reilly MP, Lloyd W, Cunningham G, Loscalzo J, Kimmel SE, Christman BW, Barst RJ. Robbins IM, et al. Among authors: yung d. Eur Respir J. 2006 Mar;27(3):578-84. doi: 10.1183/09031936.06.00095705. Eur Respir J. 2006. PMID: 16507859 Free article. Clinical Trial.
Outcomes of children with cardiomyopathy listed for transplant: a multi-institutional study.
Dipchand AI, Naftel DC, Feingold B, Spicer R, Yung D, Kaufman B, Kirklin JK, Allain-Rooney T, Hsu D; Pediatric Heart Transplant Study Investigators. Dipchand AI, et al. Among authors: yung d. J Heart Lung Transplant. 2009 Dec;28(12):1312-21. doi: 10.1016/j.healun.2009.05.019. Epub 2009 Sep 26. J Heart Lung Transplant. 2009. PMID: 19782592
The impact of heart failure severity at time of listing for cardiac transplantation on survival in pediatric cardiomyopathy.
Larsen RL, Canter CE, Naftel DC, Tressler M, Rosenthal DN, Blume ED, Mahle WT, Yung D, Morrow WR, Orav EJ, Wilkinson JD, Towbin JA, Lipshultz SE. Larsen RL, et al. Among authors: yung d. J Heart Lung Transplant. 2011 Jul;30(7):755-60. doi: 10.1016/j.healun.2011.01.718. Epub 2011 Mar 17. J Heart Lung Transplant. 2011. PMID: 21419658 Free PMC article.
Kids Mod PAH trial: A multicenter trial comparing mono- versus duo-therapy for initial treatment of pediatric pulmonary hypertension.
Collaco JM, Abman SH, Austin ED, Avitabile CM, Bates A, Fineman JR, Freire GA, Handler SS, Ivy DD, Krishnan US, Mullen MP, Varghese NP, Yung D, Nies MK, Everett AD, Zimmerman KO, Simmons W, Chakraborty H, Yenokyan G, Newell-Sturdivant A, Christensen E, Eyzaguirre LM, Hanley DF, Rosenzweig EB, Romer LH. Collaco JM, et al. Among authors: yung d. Pulm Circ. 2023 Oct 31;13(4):e12305. doi: 10.1002/pul2.12305. eCollection 2023 Oct. Pulm Circ. 2023. PMID: 37915400 Free PMC article.
Actigraphy methodology in the Kids Mod PAH trial: Physical activity as a functional endpoint in pediatric clinical trials.
Avitabile CM, Krishnan US, Yung D, Handler SS, Varghese N, Bates A, Fineman J, Sullivan R, Friere G, Austin E, Mullen MP, Pereira C, Christensen EJ, Yenokyan G, Collaco JM, Abman SH, Romer L, Dunbar Ivy D, Rosenzweig EB. Avitabile CM, et al. Among authors: yung d. Pulm Circ. 2024 Mar 8;14(1):e12339. doi: 10.1002/pul2.12339. eCollection 2024 Jan. Pulm Circ. 2024. PMID: 38464344 Free PMC article.
Apixaban for Stroke Prevention in Subclinical Atrial Fibrillation.
Healey JS, Lopes RD, Granger CB, Alings M, Rivard L, McIntyre WF, Atar D, Birnie DH, Boriani G, Camm AJ, Conen D, Erath JW, Gold MR, Hohnloser SH, Ip J, Kautzner J, Kutyifa V, Linde C, Mabo P, Mairesse G, Benezet Mazuecos J, Cosedis Nielsen J, Philippon F, Proietti M, Sticherling C, Wong JA, Wright DJ, Zarraga IG, Coutts SB, Kaplan A, Pombo M, Ayala-Paredes F, Xu L, Simek K, Nevills S, Mian R, Connolly SJ; ARTESIA Investigators. Healey JS, et al. N Engl J Med. 2024 Jan 11;390(2):107-117. doi: 10.1056/NEJMoa2310234. Epub 2023 Nov 12. N Engl J Med. 2024. PMID: 37952132 Clinical Trial.
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