Bettini M - Search Results

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107 results

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A Hybrid Insulin Epitope Maintains High 2D Affinity for Diabetogenic T Cells in the Periphery.

Liu B, Hood JD, Kolawole EM, Woodruff DM, Vignali DA, Bettini M, Evavold BD. Liu B, et al. Among authors: bettini m. Diabetes. 2020 Mar;69(3):381-391. doi: 10.2337/db19-0399. Epub 2019 Dec 5. Diabetes. 2020. PMID: 31806623 Free PMC article.

Pathogenic MOG-reactive CD8+ T cells require MOG-reactive CD4+ T cells for sustained CNS inflammation during chronic EAE.

Bettini M, Rosenthal K, Evavold BD. Bettini M, et al. J Neuroimmunol. 2009 Aug 18;213(1-2):60-8. doi: 10.1016/j.jneuroim.2009.05.017. Epub 2009 Jun 21. J Neuroimmunol. 2009. PMID: 19540601 Free PMC article.

TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential.

Bettini M, Blanchfield L, Castellaw A, Zhang Q, Nakayama M, Smeltzer MP, Zhang H, Hogquist KA, Evavold BD, Vignali DA. Bettini M, et al. J Immunol. 2014 Jul 15;193(2):571-9. doi: 10.4049/jimmunol.1400043. Epub 2014 Jun 18. J Immunol. 2014. PMID: 24943217 Free PMC article.

A Critical Insulin TCR Contact Residue Selects High-Affinity and Pathogenic Insulin-Specific T Cells.

Bettini M, Scavuzzo MA, Liu B, Kolawole E, Guo L, Evavold BD, Borowiak M, Bettini ML. Bettini M, et al. Among authors: bettini ml. Diabetes. 2020 Mar;69(3):392-400. doi: 10.2337/db19-0821. Epub 2019 Dec 13. Diabetes. 2020. PMID: 31836691 Free PMC article.

T-Cell Receptor/HLA Humanized Mice Reveal Reduced Tolerance and Increased Immunogenicity of Posttranslationally Modified GAD65 Epitope.

Jing Y, Kong Y, McGinty J, Blahnik-Fagan G, Lee T, Orozco-Figueroa S, Bettini ML, James EA, Bettini M. Jing Y, et al. Among authors: bettini m, bettini ml. Diabetes. 2022 May 1;71(5):1012-1022. doi: 10.2337/db21-0993. Diabetes. 2022. PMID: 35179565 Free PMC article.

A dormant T-cell population with autoimmune potential exhibits low self-reactivity and infiltrates islets in type 1 diabetes.

Kong Y, Jing Y, Allard D, Scavuzzo MA, Sprouse ML, Borowiak M, Bettini ML, Bettini M. Kong Y, et al. Among authors: bettini m, bettini ml. Eur J Immunol. 2022 Jul;52(7):1158-1170. doi: 10.1002/eji.202149690. Epub 2022 Apr 22. Eur J Immunol. 2022. PMID: 35389516 Free PMC article.

Antibody-Mediated Targeting of a Hybrid Insulin Peptide Toward Neonatal Thymic Langerin-Positive Cells Enhances T-Cell Central Tolerance and Delays Autoimmune Diabetes.

Lin Y, Perovanovic J, Kong Y, Igyarto BZ, Zurawski S, Tantin D, Zurawski G, Bettini M, Bettini ML. Lin Y, et al. Among authors: bettini m, bettini ml. Diabetes. 2022 Aug 1;71(8):1735-1745. doi: 10.2337/db21-1069. Diabetes. 2022. PMID: 35622068 Free PMC article.

Increased TCR signaling in regulatory T cells is disengaged from TCR affinity.

Jing Y, Kong Y, Allard D, Liu B, Kolawole E, Sprouse M, Evavold B, Bettini M, Bettini M. Jing Y, et al. Among authors: bettini m. bioRxiv [Preprint]. 2023 Jan 24:2023.01.17.523999. doi: 10.1101/2023.01.17.523999. bioRxiv. 2023. PMID: 36711832 Free PMC article. Preprint.

Immunogen-Specific Strengths and Limitations of the Activation-Induced Marker Assay for Assessing Murine Antigen-Specific CD4+ T Cell Responses.

Nguyen NX, Richens AW, Sircy LM, Allard DE, Kolawole EM, Evavold BD, Bettini M, Hale JS. Nguyen NX, et al. Among authors: bettini m. J Immunol. 2023 Apr 1;210(7):916-925. doi: 10.4049/jimmunol.2200638. J Immunol. 2023. PMID: 36883856 Free PMC article.

The amphiregulin/EGFR axis has limited contribution in controlling autoimmune diabetes.

Raugh A, Jing Y, Bettini ML, Bettini M. Raugh A, et al. Among authors: bettini m, bettini ml. Sci Rep. 2023 Oct 30;13(1):18653. doi: 10.1038/s41598-023-45738-4. Sci Rep. 2023. PMID: 37903947 Free PMC article.

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