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Page 1
Interferon-γ Drives Treg Fragility to Promote Anti-tumor Immunity.
Overacre-Delgoffe AE, Chikina M, Dadey RE, Yano H, Brunazzi EA, Shayan G, Horne W, Moskovitz JM, Kolls JK, Sander C, Shuai Y, Normolle DP, Kirkwood JM, Ferris RL, Delgoffe GM, Bruno TC, Workman CJ, Vignali DAA. Overacre-Delgoffe AE, et al. Among authors: bruno tc. Cell. 2017 Jun 1;169(6):1130-1141.e11. doi: 10.1016/j.cell.2017.05.005. Epub 2017 May 25. Cell. 2017. PMID: 28552348 Free PMC article.
Adaptive plasticity of IL-10+ and IL-35+ Treg cells cooperatively promotes tumor T cell exhaustion.
Sawant DV, Yano H, Chikina M, Zhang Q, Liao M, Liu C, Callahan DJ, Sun Z, Sun T, Tabib T, Pennathur A, Corry DB, Luketich JD, Lafyatis R, Chen W, Poholek AC, Bruno TC, Workman CJ, Vignali DAA. Sawant DV, et al. Among authors: bruno tc. Nat Immunol. 2019 Jun;20(6):724-735. doi: 10.1038/s41590-019-0346-9. Epub 2019 Apr 1. Nat Immunol. 2019. PMID: 30936494 Free PMC article.
Neuropilin-1 is a T cell memory checkpoint limiting long-term antitumor immunity.
Liu C, Somasundaram A, Manne S, Gocher AM, Szymczak-Workman AL, Vignali KM, Scott EN, Normolle DP, John Wherry E, Lipson EJ, Ferris RL, Bruno TC, Workman CJ, Vignali DAA. Liu C, et al. Among authors: bruno tc. Nat Immunol. 2020 Sep;21(9):1010-1021. doi: 10.1038/s41590-020-0733-2. Epub 2020 Jul 13. Nat Immunol. 2020. PMID: 32661362 Free PMC article.
Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding.
Andrews LP, Somasundaram A, Moskovitz JM, Szymczak-Workman AL, Liu C, Cillo AR, Lin H, Normolle DP, Moynihan KD, Taniuchi I, Irvine DJ, Kirkwood JM, Lipson EJ, Ferris RL, Bruno TC, Workman CJ, Vignali DAA. Andrews LP, et al. Among authors: bruno tc. Sci Immunol. 2020 Jul 17;5(49):eabc2728. doi: 10.1126/sciimmunol.abc2728. Sci Immunol. 2020. PMID: 32680952 Free PMC article.
Intractable Coronavirus Disease 2019 (COVID-19) and Prolonged Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Replication in a Chimeric Antigen Receptor-Modified T-Cell Therapy Recipient: A Case Study.
Hensley MK, Bain WG, Jacobs J, Nambulli S, Parikh U, Cillo A, Staines B, Heaps A, Sobolewski MD, Rennick LJ, Macatangay BJC, Klamar-Blain C, Kitsios GD, Methé B, Somasundaram A, Bruno TC, Cardello C, Shan F, Workman C, Ray P, Ray A, Lee J, Sethi R, Schwarzmann WE, Ladinsky MS, Bjorkman PJ, Vignali DA, Duprex WP, Agha ME, Mellors JW, McCormick KD, Morris A, Haidar G. Hensley MK, et al. Among authors: bruno tc. Clin Infect Dis. 2021 Aug 2;73(3):e815-e821. doi: 10.1093/cid/ciab072. Clin Infect Dis. 2021. PMID: 33507235 Free PMC article.
COVID-19 versus Non-COVID-19 Acute Respiratory Distress Syndrome: Comparison of Demographics, Physiologic Parameters, Inflammatory Biomarkers, and Clinical Outcomes.
Bain W, Yang H, Shah FA, Suber T, Drohan C, Al-Yousif N, DeSensi RS, Bensen N, Schaefer C, Rosborough BR, Somasundaram A, Workman CJ, Lampenfeld C, Cillo AR, Cardello C, Shan F, Bruno TC, Vignali DAA, Ray P, Ray A, Zhang Y, Lee JS, Methé B, McVerry BJ, Morris A, Kitsios GD. Bain W, et al. Among authors: bruno tc. Ann Am Thorac Soc. 2021 Jul;18(7):1202-1210. doi: 10.1513/AnnalsATS.202008-1026OC. Ann Am Thorac Soc. 2021. PMID: 33544045 Free PMC article.
Bifurcated monocyte states are predictive of mortality in severe COVID-19.
Cillo AR, Somasundaram A, Shan F, Cardello C, Workman CJ, Kitsios GD, Ruffin A, Kunning S, Lampenfeld C, Onkar S, Grebinoski S, Deshmukh G, Methe B, Liu C, Nambulli S, Andrews L, Duprex WP, Joglekar AV, Benos PV, Ray P, Ray A, McVerry BJ, Zhang Y, Lee JS, Das J, Singh H, Morris A, Bruno TC, Vignali DAA. Cillo AR, et al. Among authors: bruno tc. bioRxiv [Preprint]. 2021 Feb 10:2021.02.10.430499. doi: 10.1101/2021.02.10.430499. bioRxiv. 2021. PMID: 33594364 Free PMC article. Preprint.
108 results