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1,302 results

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An integrated single-cell RNA-seq map of human neuroblastoma tumors and preclinical models uncovers divergent mesenchymal-like gene expression programs.
Chapple RH, Liu X, Natarajan S, Alexander MIM, Kim Y, Patel AG, LaFlamme CW, Pan M, Wright WC, Lee HM, Zhang Y, Lu M, Koo SC, Long C, Harper J, Savage C, Johnson MD, Confer T, Akers WJ, Dyer MA, Sheppard H, Easton J, Geeleher P. Chapple RH, et al. Among authors: johnson md. Genome Biol. 2024 Jun 19;25(1):161. doi: 10.1186/s13059-024-03309-4. Genome Biol. 2024. PMID: 38898465 Free PMC article.
Preclinical models for neuroblastoma: establishing a baseline for treatment.
Teitz T, Stanke JJ, Federico S, Bradley CL, Brennan R, Zhang J, Johnson MD, Sedlacik J, Inoue M, Zhang ZM, Frase S, Rehg JE, Hillenbrand CM, Finkelstein D, Calabrese C, Dyer MA, Lahti JM. Teitz T, et al. Among authors: johnson md. PLoS One. 2011 Apr 29;6(4):e19133. doi: 10.1371/journal.pone.0019133. PLoS One. 2011. PMID: 21559450 Free PMC article.
Targeting the spliceosome through RBM39 degradation results in exceptional responses in high-risk neuroblastoma models.
Singh S, Quarni W, Goralski M, Wan S, Jin H, Van de Velde LA, Fang J, Wu Q, Abu-Zaid A, Wang T, Singh R, Craft D, Fan Y, Confer T, Johnson M, Akers WJ, Wang R, Murray PJ, Thomas PG, Nijhawan D, Davidoff AM, Yang J. Singh S, et al. Sci Adv. 2021 Nov 19;7(47):eabj5405. doi: 10.1126/sciadv.abj5405. Epub 2021 Nov 17. Sci Adv. 2021. PMID: 34788094 Free PMC article.
Conditional Activation of c-MYC in Distinct Catecholaminergic Cells Drives Development of Neuroblastoma or Somatostatinoma.
Wang T, Liu L, Fang J, Jin H, Natarajan S, Sheppard H, Lu M, Turner G, Confer T, Johnson M, Steinberg J, Ha L, Yadak N, Jain R, Picketts DJ, Ma X, Murphy A, Davidoff AM, Glazer ES, Easton J, Chen X, Wang R, Yang J. Wang T, et al. Cancer Res. 2025 Feb 1;85(3):424-441. doi: 10.1158/0008-5472.CAN-24-1142. Cancer Res. 2025. PMID: 39531507 Free PMC article.
Venetoclax plus gilteritinib is effective in preclinical models of FLT3-mutant BCL11B-a lineage-ambiguous leukemia.
Montefiori LE, Iacobucci I, Gao Q, Moore J, Wright WC, Wei H, Baviskar P, Sona S, Jin H, Budhraja A, Lott J, Tatarata QZ, Cheng Z, Khan T, Backhaus Wagner EA, Johnson M, Mehr CM, Freeman B, Janke L, Haferlach T, Geeleher P, Mead PE, Konopleva M, Opferman JT, Mullighan CG. Montefiori LE, et al. Blood. 2025 Nov 6;146(19):2350-2356. doi: 10.1182/blood.2025028985. Blood. 2025. PMID: 40811853 Free PMC article.
RBM39 degrader invigorates innate immunity to eradicate neuroblastoma despite cancer cell plasticity.
Singh S, Fang J, Jin H, Van De Velde LA, Cortes A, Chen J, Natarajan S, Poon E, Wu Q, Morton CL, Woolard MA, Quarni W, Steele JA, Connelly JP, He L, Thorne R, Turner G, Confer T, Johnson M, Caufield WV, Freeman BB 3rd, Lockey T, Murphy AJ, Murray PJ, Owa T, Pruett-Miller SM, Wang R, Chesler L, Park JR, Davidoff AM, Easton J, Chen X, Thomas PG, Yang J. Singh S, et al. Nat Commun. 2025 Sep 17;16(1):8287. doi: 10.1038/s41467-025-63979-x. Nat Commun. 2025. PMID: 40962798 Free PMC article.
1,302 results