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Page 1
Prognostic impact and causality of age on oncological outcomes in women with endometrial cancer: a multimethod analysis of the randomised PORTEC-1, PORTEC-2, and PORTEC-3 trials.
Wakkerman FC, Wu J, Putter H, Jürgenliemk-Schulz IM, Jobsen JJ, Lutgens LCHW, Haverkort MAD, de Jong MA, Mens JWM, Wortman BG, Nout RA, Léon-Castillo A, Powell ME, Mileshkin LR, Katsaros D, Alfieri J, Leary A, Singh N, de Boer SM, Nijman HW, Smit VTHBM, Bosse T, Koelzer VH, Creutzberg CL, Horeweg N. Wakkerman FC, et al. Among authors: koelzer vh. Lancet Oncol. 2024 Jun;25(6):779-789. doi: 10.1016/S1470-2045(24)00142-6. Epub 2024 Apr 30. Lancet Oncol. 2024. PMID: 38701815
Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia.
Gil Vazquez E, Nasreddin N, Valbuena GN, Mulholland EJ, Belnoue-Davis HL, Eggington HR, Schenck RO, Wouters VM, Wirapati P, Gilroy K, Lannagan TRM, Flanagan DJ, Najumudeen AK, Omwenga S, McCorry AMB, Easton A, Koelzer VH, East JE, Morton D, Trusolino L, Maughan T, Campbell AD, Loughrey MB, Dunne PD, Tsantoulis P, Huels DJ, Tejpar S, Sansom OJ, Leedham SJ. Gil Vazquez E, et al. Among authors: koelzer vh. Cell Stem Cell. 2022 Nov 3;29(11):1612. doi: 10.1016/j.stem.2022.09.005. Cell Stem Cell. 2022. PMID: 36332574 Free PMC article. No abstract available.
Multiplex analysis of intratumoural immune infiltrate and prognosis in patients with stage II-III colorectal cancer from the SCOT and QUASAR 2 trials: a retrospective analysis.
Frei AL, McGuigan A, Sinha RRAK, Jabbar F, Gneo L, Tomasevic T, Harkin A, Iveson T, Saunders MP, Oien KA, Maka N, Pezzella F, Campo L, Browne M, Glaire M, Kildal W, Danielsen HE, Hay J, Edwards J, Sansom O, Kelly C, Tomlinson I, Kerr R, Kerr D, Domingo E; TransSCOT consortium; Church DN, Koelzer VH. Frei AL, et al. Among authors: koelzer vh. Lancet Oncol. 2024 Feb;25(2):198-211. doi: 10.1016/S1470-2045(23)00560-0. Lancet Oncol. 2024. PMID: 38301689 Free article.
Tumour purity assessment with deep learning in colorectal cancer and impact on molecular analysis.
Schoenpflug LA, Chatzipli A, Sirinukunwattana K, Richman S, Blake A, Robineau J, Mertz KD, Verrill C, Leedham SJ, Hardy C, Whalley C, Redmond K, Dunne P, Walker S, Beggs AD, McDermott U, Murray GI, Samuel LM, Seymour M, Tomlinson I, Quirke P; S:CORT consortium; Rittscher J, Maughan T, Domingo E, Koelzer VH. Schoenpflug LA, et al. Among authors: koelzer vh. J Pathol. 2025 Feb;265(2):184-197. doi: 10.1002/path.6376. Epub 2024 Dec 22. J Pathol. 2025. PMID: 39710952 Free PMC article.
Identification and validation of a machine learning model of complete response to radiation in rectal cancer reveals immune infiltrate and TGFβ as key predictors.
Domingo E, Rathee S, Blake A, Samuel L, Murray G, Sebag-Montefiore D, Gollins S, West N, Begum R, Richman S, Quirke P, Redmond K, Chatzipli A, Barberis A, Hassanieh S, Mahmood U, Youdell M, McDermott U, Koelzer V, Leedham S, Tomlinson I, Dunne P; S:CORT consortium; Buffa FM, Maughan TS. Domingo E, et al. EBioMedicine. 2024 Aug;106:105228. doi: 10.1016/j.ebiom.2024.105228. Epub 2024 Jul 16. EBioMedicine. 2024. PMID: 39013324 Free PMC article.
Transformer-based biomarker prediction from colorectal cancer histology: A large-scale multicentric study.
Wagner SJ, Reisenbüchler D, West NP, Niehues JM, Zhu J, Foersch S, Veldhuizen GP, Quirke P, Grabsch HI, van den Brandt PA, Hutchins GGA, Richman SD, Yuan T, Langer R, Jenniskens JCA, Offermans K, Mueller W, Gray R, Gruber SB, Greenson JK, Rennert G, Bonner JD, Schmolze D, Jonnagaddala J, Hawkins NJ, Ward RL, Morton D, Seymour M, Magill L, Nowak M, Hay J, Koelzer VH, Church DN; TransSCOT consortium; Matek C, Geppert C, Peng C, Zhi C, Ouyang X, James JA, Loughrey MB, Salto-Tellez M, Brenner H, Hoffmeister M, Truhn D, Schnabel JA, Boxberg M, Peng T, Kather JN. Wagner SJ, et al. Among authors: koelzer vh. Cancer Cell. 2023 Sep 11;41(9):1650-1661.e4. doi: 10.1016/j.ccell.2023.08.002. Epub 2023 Aug 30. Cancer Cell. 2023. PMID: 37652006 Free PMC article.
Poor Diagnostic Reproducibility in the Identification of Nonconventional Dysplasia in Colitis Impacts the Application of Histologic Stratification Tools.
Nasreddin N, Jansen M, Loughrey MB, Wang LM, Koelzer VH, Rodriguez-Justo M, Novelli M, Fisher J, Brown MW, Al Bakir I, Hart AL, Dunne P, Graham TA, Leedham SJ. Nasreddin N, et al. Among authors: koelzer vh. Mod Pathol. 2024 Mar;37(3):100419. doi: 10.1016/j.modpat.2023.100419. Epub 2023 Dec 27. Mod Pathol. 2024. PMID: 38158125 Free article.
A review on federated learning in computational pathology.
Schoenpflug LA, Nie Y, Sheikhzadeh F, Koelzer VH. Schoenpflug LA, et al. Among authors: koelzer vh. Comput Struct Biotechnol J. 2024 Oct 29;23:3938-3945. doi: 10.1016/j.csbj.2024.10.037. eCollection 2024 Dec. Comput Struct Biotechnol J. 2024. PMID: 39582895 Free PMC article. Review.
Tumor immune dynamics and long-term clinical outcome of stage IIIA NSCLC patients treated with neoadjuvant chemoimmunotherapy.
Schmid D, Sobottka B, Manzo M, Trüb M, Leonards K, Herzig P, Oyewole OR, Jermann P, Hayoz S, Savic Prince S, Tochtermann G, Natoli M, Pless M, Bettini A, Früh M, Mauti LA, Britschgi C, Peters S, Mark M, Ochsenbein AF, Janthur WD, Waibel C, Mach N, Froesch P, Buess M, Bohanes P, Gonzalez M, Alborelli I, Rothschild SI, Koelzer VH, Zippelius A. Schmid D, et al. Among authors: koelzer vh. Nat Commun. 2025 Sep 30;16(1):8673. doi: 10.1038/s41467-025-63696-5. Nat Commun. 2025. PMID: 41027867 Free PMC article.
136 results