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Causal integration of multi-omics data with prior knowledge to generate mechanistic hypotheses.
Dugourd A, Kuppe C, Sciacovelli M, Gjerga E, Gabor A, Emdal KB, Vieira V, Bekker-Jensen DB, Kranz J, Bindels EMJ, Costa ASH, Sousa A, Beltrao P, Rocha M, Olsen JV, Frezza C, Kramann R, Saez-Rodriguez J. Dugourd A, et al. Among authors: kranz j. Mol Syst Biol. 2021 Jan;17(1):e9730. doi: 10.15252/msb.20209730. Mol Syst Biol. 2021. PMID: 33502086 Free PMC article.
Decoding myofibroblast origins in human kidney fibrosis.
Kuppe C, Ibrahim MM, Kranz J, Zhang X, Ziegler S, Perales-Patón J, Jansen J, Reimer KC, Smith JR, Dobie R, Wilson-Kanamori JR, Halder M, Xu Y, Kabgani N, Kaesler N, Klaus M, Gernhold L, Puelles VG, Huber TB, Boor P, Menzel S, Hoogenboezem RM, Bindels EMJ, Steffens J, Floege J, Schneider RK, Saez-Rodriguez J, Henderson NC, Kramann R. Kuppe C, et al. Among authors: kranz j. Nature. 2021 Jan;589(7841):281-286. doi: 10.1038/s41586-020-2941-1. Epub 2020 Nov 11. Nature. 2021. PMID: 33176333 Free PMC article.
Deep learning-based molecular morphometrics for kidney biopsies.
Zimmermann M, Klaus M, Wong MN, Thebille AK, Gernhold L, Kuppe C, Halder M, Kranz J, Wanner N, Braun F, Wulf S, Wiech T, Panzer U, Krebs CF, Hoxha E, Kramann R, Huber TB, Bonn S, Puelles VG. Zimmermann M, et al. Among authors: kranz j. JCI Insight. 2021 Apr 8;6(7):e144779. doi: 10.1172/jci.insight.144779. JCI Insight. 2021. PMID: 33705360 Free PMC article.
[Urosepsis-targeted diagnostics and effective therapy].
Kranz J, Stangl F, Kuppe C, Wagenlehner F, Saar M, Schneidewind L. Kranz J, et al. Urologie. 2022 Jun;61(6):596-601. doi: 10.1007/s00120-022-01832-5. Epub 2022 May 6. Urologie. 2022. PMID: 35522262 Review. German.
Adult human kidney organoids originate from CD24+ cells and represent an advanced model for adult polycystic kidney disease.
Xu Y, Kuppe C, Perales-Patón J, Hayat S, Kranz J, Abdallah AT, Nagai J, Li Z, Peisker F, Saritas T, Halder M, Menzel S, Hoeft K, Kenter A, Kim H, van Roeyen CRC, Lehrke M, Moellmann J, Speer T, Buhl EM, Hoogenboezem R, Boor P, Jansen J, Knopp C, Kurth I, Smeets B, Bindels E, Reinders MEJ, Baan C, Gribnau J, Hoorn EJ, Steffens J, Huber TB, Costa I, Floege J, Schneider RK, Saez-Rodriguez J, Freedman BS, Kramann R. Xu Y, et al. Among authors: kranz j. Nat Genet. 2022 Nov;54(11):1690-1701. doi: 10.1038/s41588-022-01202-z. Epub 2022 Oct 27. Nat Genet. 2022. PMID: 36303074 Free PMC article.
[Urological dermatosis].
Kranz J, Anheuser P, Lichtenstein H, Steffens J. Kranz J, et al. Urologe A. 2013 Oct;52(10):1392-405. doi: 10.1007/s00120-013-3172-y. Urologe A. 2013. PMID: 24068322 Review. German.
257 results