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68,273 results

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Targeting regulatory T cells in tumors.
Liu C, Workman CJ, Vignali DA. Liu C, et al. FEBS J. 2016 Jul;283(14):2731-48. doi: 10.1111/febs.13656. Epub 2016 Mar 1. FEBS J. 2016. PMID: 26787424 Free article. Review.
Neuropilin-1 is a T cell memory checkpoint limiting long-term antitumor immunity.
Liu C, Somasundaram A, Manne S, Gocher AM, Szymczak-Workman AL, Vignali KM, Scott EN, Normolle DP, John Wherry E, Lipson EJ, Ferris RL, Bruno TC, Workman CJ, Vignali DAA. Liu C, et al. Nat Immunol. 2020 Sep;21(9):1010-1021. doi: 10.1038/s41590-020-0733-2. Epub 2020 Jul 13. Nat Immunol. 2020. PMID: 32661362 Free PMC article.
Adaptive plasticity of IL-10+ and IL-35+ Treg cells cooperatively promotes tumor T cell exhaustion.
Sawant DV, Yano H, Chikina M, Zhang Q, Liao M, Liu C, Callahan DJ, Sun Z, Sun T, Tabib T, Pennathur A, Corry DB, Luketich JD, Lafyatis R, Chen W, Poholek AC, Bruno TC, Workman CJ, Vignali DAA. Sawant DV, et al. Among authors: liu c. Nat Immunol. 2019 Jun;20(6):724-735. doi: 10.1038/s41590-019-0346-9. Epub 2019 Apr 1. Nat Immunol. 2019. PMID: 30936494 Free PMC article.
Treg Cells Promote the SREBP1-Dependent Metabolic Fitness of Tumor-Promoting Macrophages via Repression of CD8+ T Cell-Derived Interferon-γ.
Liu C, Chikina M, Deshpande R, Menk AV, Wang T, Tabib T, Brunazzi EA, Vignali KM, Sun M, Stolz DB, Lafyatis RA, Chen W, Delgoffe GM, Workman CJ, Wendell SG, Vignali DAA. Liu C, et al. Immunity. 2019 Aug 20;51(2):381-397.e6. doi: 10.1016/j.immuni.2019.06.017. Epub 2019 Jul 23. Immunity. 2019. PMID: 31350177 Free PMC article.
Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding.
Andrews LP, Somasundaram A, Moskovitz JM, Szymczak-Workman AL, Liu C, Cillo AR, Lin H, Normolle DP, Moynihan KD, Taniuchi I, Irvine DJ, Kirkwood JM, Lipson EJ, Ferris RL, Bruno TC, Workman CJ, Vignali DAA. Andrews LP, et al. Among authors: liu c. Sci Immunol. 2020 Jul 17;5(49):eabc2728. doi: 10.1126/sciimmunol.abc2728. Sci Immunol. 2020. PMID: 32680952 Free PMC article.
People critically ill with COVID-19 exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 lung viral burden.
Cillo AR, Somasundaram A, Shan F, Cardello C, Workman CJ, Kitsios GD, Ruffin AT, Kunning S, Lampenfeld C, Onkar S, Grebinoski S, Deshmukh G, Methe B, Liu C, Nambulli S, Andrews LP, Duprex WP, Joglekar AV, Benos PV, Ray P, Ray A, McVerry BJ, Zhang Y, Lee JS, Das J, Singh H, Morris A, Bruno TC, Vignali DAA. Cillo AR, et al. Among authors: liu c. Cell Rep Med. 2021 Dec 21;2(12):100476. doi: 10.1016/j.xcrm.2021.100476. Epub 2021 Dec 2. Cell Rep Med. 2021. PMID: 34873589 Free PMC article.
Neuronally expressed PDL1, not PD1, suppresses acute nociception.
Meerschaert KA, Edwards BS, Epouhe AY, Jefferson B, Friedman R, Babyok OL, Moy JK, Kehinde F, Liu C, Workman CJ, Vignali DAA, Albers KM, Koerber HR, Gold MS, Davis BM, Scheff NN, Saloman JL. Meerschaert KA, et al. Among authors: liu c. Brain Behav Immun. 2022 Nov;106:233-246. doi: 10.1016/j.bbi.2022.09.001. Epub 2022 Sep 8. Brain Behav Immun. 2022. PMID: 36089217
Bifurcated monocyte states are predictive of mortality in severe COVID-19.
Cillo AR, Somasundaram A, Shan F, Cardello C, Workman CJ, Kitsios GD, Ruffin A, Kunning S, Lampenfeld C, Onkar S, Grebinoski S, Deshmukh G, Methe B, Liu C, Nambulli S, Andrews L, Duprex WP, Joglekar AV, Benos PV, Ray P, Ray A, McVerry BJ, Zhang Y, Lee JS, Das J, Singh H, Morris A, Bruno TC, Vignali DAA. Cillo AR, et al. Among authors: liu c. bioRxiv. 2021 Feb 10:2021.02.10.430499. doi: 10.1101/2021.02.10.430499. Preprint. bioRxiv. 2021. PMID: 33594364 Free PMC article.
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