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Stem-like intestinal Th17 cells give rise to pathogenic effector T cells during autoimmunity.
Schnell A, Huang L, Singer M, Singaraju A, Barilla RM, Regan BML, Bollhagen A, Thakore PI, Dionne D, Delorey TM, Pawlak M, Meyer Zu Horste G, Rozenblatt-Rosen O, Irizarry RA, Regev A, Kuchroo VK. Schnell A, et al. Among authors: regan bml. Cell. 2021 Dec 22;184(26):6281-6298.e23. doi: 10.1016/j.cell.2021.11.018. Epub 2021 Dec 6. Cell. 2021. PMID: 34875227 Free PMC article.
Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling.
Pawlak M, DeTomaso D, Schnell A, Meyer Zu Horste G, Lee Y, Nyman J, Dionne D, Regan BML, Singh V, Delorey T, Schramm MA, Wang C, Wallrapp A, Burkett PR, Riesenfeld SJ, Anderson AC, Regev A, Xavier RJ, Yosef N, Kuchroo VK. Pawlak M, et al. Among authors: regan bml. Immunity. 2022 Sep 13;55(9):1663-1679.e6. doi: 10.1016/j.immuni.2022.08.007. Epub 2022 Sep 6. Immunity. 2022. PMID: 36070768 Free PMC article.
Targeting PGLYRP1 promotes antitumor immunity while inhibiting autoimmune neuroinflammation.
Schnell A, Huang L, Regan BML, Singh V, Vonficht D, Bollhagen A, Wang M, Hou Y, Bod L, Sobel RA, Chihara N, Madi A, Anderson AC, Regev A, Kuchroo VK. Schnell A, et al. Among authors: regan bml. Nat Immunol. 2023 Nov;24(11):1908-1920. doi: 10.1038/s41590-023-01645-4. Epub 2023 Oct 12. Nat Immunol. 2023. PMID: 37828379 Free PMC article.