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Hit-to-Lead Optimization of Mouse Trace Amine Associated Receptor 1 (mTAAR1) Agonists with a Diphenylmethane-Scaffold: Design, Synthesis, and Biological Study.
Chiellini G, Nesi G, Sestito S, Chiarugi S, Runfola M, Espinoza S, Sabatini M, Bellusci L, Laurino A, Cichero E, Gainetdinov RR, Fossa P, Raimondi L, Zucchi R, Rapposelli S. Chiellini G, et al. Among authors: runfola m. J Med Chem. 2016 Nov 10;59(21):9825-9836. doi: 10.1021/acs.jmedchem.6b01092. Epub 2016 Oct 21. J Med Chem. 2016. PMID: 27731647
Collecting data through high throughput in vitro early toxicity and off-target liability assays to rapidly identify limitations of novel thyromimetics.
Runfola M, Sestito S, Gul S, Chiellini G, Rapposelli S. Runfola M, et al. Data Brief. 2020 Jan 31;29:105206. doi: 10.1016/j.dib.2020.105206. eCollection 2020 Apr. Data Brief. 2020. PMID: 32071982 Free PMC article.
The data reported herein support our research article entitled "Design, synthesis and biological evaluation of novel TRbeta selective agonists sustained by ADME-Toxicity analysis" by Runfola M., Sestito S., et al. [1]....
The data reported herein support our research article entitled "Design, synthesis and biological evaluation of novel TRbeta selective agonis …
42 results