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Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme.
Sestito S, Nesi G, Daniele S, Martelli A, Digiacomo M, Borghini A, Pietra D, Calderone V, Lapucci A, Falasca M, Parrella P, Notarangelo A, Breschi MC, Macchia M, Martini C, Rapposelli S. Sestito S, et al. Eur J Med Chem. 2015 Nov 13;105:274-88. doi: 10.1016/j.ejmech.2015.10.020. Epub 2015 Oct 22. Eur J Med Chem. 2015. PMID: 26498573
Memantine prodrug as a new agent for Alzheimer's Disease.
Sestito S, Daniele S, Pietrobono D, Citi V, Bellusci L, Chiellini G, Calderone V, Martini C, Rapposelli S. Sestito S, et al. Sci Rep. 2019 Mar 15;9(1):4612. doi: 10.1038/s41598-019-40925-8. Sci Rep. 2019. PMID: 30874573 Free PMC article.
113 results