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Serial crystallography captures dynamic control of sequential electron and proton transfer events in a flavoenzyme.
Maestre-Reyna M, Yang CH, Nango E, Huang WC, Ngurah Putu EPG, Wu WJ, Wang PH, Franz-Badur S, Saft M, Emmerich HJ, Wu HY, Lee CC, Huang KF, Chang YK, Liao JH, Weng JH, Gad W, Chang CW, Pang AH, Sugahara M, Owada S, Hosokawa Y, Joti Y, Yamashita A, Tanaka R, Tanaka T, Luo F, Tono K, Hsu KC, Kiontke S, Schapiro I, Spadaccini R, Royant A, Yamamoto J, Iwata S, Essen LO, Bessho Y, Tsai MD. Maestre-Reyna M, et al. Among authors: wu hy, wu wj. Nat Chem. 2022 Jun;14(6):677-685. doi: 10.1038/s41557-022-00922-3. Epub 2022 Apr 7. Nat Chem. 2022. PMID: 35393554
An ATP-sensitive phosphoketolase regulates carbon fixation in cyanobacteria.
Lu KJ, Chang CW, Wang CH, Chen FY, Huang IY, Huang PH, Yang CH, Wu HY, Wu WJ, Hsu KC, Ho MC, Tsai MD, Liao JC. Lu KJ, et al. Among authors: wu hy, wu wj. Nat Metab. 2023 Jul;5(7):1111-1126. doi: 10.1038/s42255-023-00831-w. Epub 2023 Jun 22. Nat Metab. 2023. PMID: 37349485 Free PMC article.
Visualizing the DNA repair process by a photolyase at atomic resolution.
Maestre-Reyna M, Wang PH, Nango E, Hosokawa Y, Saft M, Furrer A, Yang CH, Gusti Ngurah Putu EP, Wu WJ, Emmerich HJ, Caramello N, Franz-Badur S, Yang C, Engilberge S, Wranik M, Glover HL, Weinert T, Wu HY, Lee CC, Huang WC, Huang KF, Chang YK, Liao JH, Weng JH, Gad W, Chang CW, Pang AH, Yang KC, Lin WT, Chang YC, Gashi D, Beale E, Ozerov D, Nass K, Knopp G, Johnson PJM, Cirelli C, Milne C, Bacellar C, Sugahara M, Owada S, Joti Y, Yamashita A, Tanaka R, Tanaka T, Luo F, Tono K, Zarzycka W, Müller P, Alahmad MA, Bezold F, Fuchs V, Gnau P, Kiontke S, Korf L, Reithofer V, Rosner CJ, Seiler EM, Watad M, Werel L, Spadaccini R, Yamamoto J, Iwata S, Zhong D, Standfuss J, Royant A, Bessho Y, Essen LO, Tsai MD. Maestre-Reyna M, et al. Among authors: wu hy, wu wj. Science. 2023 Dec;382(6674):eadd7795. doi: 10.1126/science.add7795. Epub 2023 Dec 1. Science. 2023. PMID: 38033054
Development of Novel Irreversible Pyruvate Kinase M2 Inhibitors.
Hsieh IS, Gopula B, Chou CC, Wu HY, Chang GD, Wu WJ, Chang CS, Chu PC, Chen CS. Hsieh IS, et al. Among authors: wu hy, wu wj. J Med Chem. 2019 Sep 26;62(18):8497-8510. doi: 10.1021/acs.jmedchem.9b00763. Epub 2019 Sep 16. J Med Chem. 2019. PMID: 31465224
Structural basis of antizyme-mediated regulation of polyamine homeostasis.
Wu HY, Chen SF, Hsieh JY, Chou F, Wang YH, Lin WT, Lee PY, Yu YJ, Lin LY, Lin TS, Lin CL, Liu GY, Tzeng SR, Hung HC, Chan NL. Wu HY, et al. Proc Natl Acad Sci U S A. 2015 Sep 8;112(36):11229-34. doi: 10.1073/pnas.1508187112. Epub 2015 Aug 24. Proc Natl Acad Sci U S A. 2015. PMID: 26305948 Free PMC article.
1,812 results