Hemolytic anemia following succimer administration in a glucose-6-phosphate dehydrogenase deficient patient

J Toxicol Clin Toxicol. 1994;32(5):569-75. doi: 10.3109/15563659409011061.

Abstract

Because of its favorable side effects profile, the oral chelating agent dimercaptosuccinic acid is often used for treatment of lead intoxication. We report a case of a 45-year-old black male with glucose-6-phosphate dehydrogenase deficiency and a 17 year history of occupational lead exposure who developed hemolysis during treatment with dimercaptosuccinic acid for symptomatic lead intoxication.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Anemia, Hemolytic / chemically induced*
  • Chelation Therapy*
  • Glucosephosphate Dehydrogenase Deficiency*
  • Humans
  • Lead Poisoning / therapy*
  • Male
  • Middle Aged
  • Occupational Diseases / therapy*
  • Succimer / adverse effects*

Substances

  • Succimer