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The following term was not found in PubMed: HOX3I
Page 1
HOXC10 promotes proliferation and invasion and induces immunosuppressive gene expression in glioma.
Li S, Zhang W, Wu C, Gao H, Yu J, Wang X, Li B, Jun Z, Zhang W, Zhou P, Shi J, Wang L, Gao Y, Li S, Tao B. Li S, et al. FEBS J. 2018 Jun;285(12):2278-2291. doi: 10.1111/febs.14476. Epub 2018 May 25. FEBS J. 2018. PMID: 29676849 Free article.
In addition, HOXC10 knock-down suppressed the expression of genes that are involved in tumor immunosuppression, including those for transforming growth factor-beta 2, PD-L2, CCL2 and TDO2. A ChIP assay showed that HOXC10 directly bound to the PD-L2 and TDO2 p …
In addition, HOXC10 knock-down suppressed the expression of genes that are involved in tumor immunosuppression, including thos …
[The effect of HOXC10 gene on biological behaviors of glioma cells and mechanism in tumor microenvironment].
Jiang WY, Lei QY, Liu SS, Yang L, Yang B, Zhang Y. Jiang WY, et al. Zhonghua Zhong Liu Za Zhi. 2022 Mar 23;44(3):228-237. doi: 10.3760/cma.j.cn112152-20200326-00266. Zhonghua Zhong Liu Za Zhi. 2022. PMID: 35316872 Chinese.
Objective: To study the effects of Homeobox C10 (HOXC10) on biological characteristics such as migration, invasion and proliferation of glioma cancer cells and to explore the role of HOXC10 gene in glioma microenvironment. ...The expressions level of M1-relat …
Objective: To study the effects of Homeobox C10 (HOXC10) on biological characteristics such as migration, invasion and proliferation …
Pan-cancer analysis of homeodomain-containing gene C10 and its carcinogenesis in lung adenocarcinoma.
Tan X, Li Z, Xie H, Chen J, Xiao J, Zhi Y, Mo H, Huang Y, Liu A. Tan X, et al. Aging (Albany NY). 2023 Dec 27;15(24):15243-15266. doi: 10.18632/aging.205348. Epub 2023 Dec 27. Aging (Albany NY). 2023. PMID: 38154103 Free PMC article.
We found elevated homeodomain-containing gene C10 (HOXC10) showed dual roles in cancers' prognosis. Some signal pathways associated with tumor were totally positively enriched in HOXC10 for whole cancers. ...The correlations of HOXC10 with immune-relat …
We found elevated homeodomain-containing gene C10 (HOXC10) showed dual roles in cancers' prognosis. Some signal pathways assoc …
HOXC10 overexpression promotes cell proliferation and migration in gastric cancer.
Kim J, Bae DH, Kim JH, Song KS, Kim YS, Kim SY. Kim J, et al. Oncol Rep. 2019 Jul;42(1):202-212. doi: 10.3892/or.2019.7164. Epub 2019 May 17. Oncol Rep. 2019. PMID: 31115563 Free PMC article.
By RNA-sequencing of AGS cells with ectopic HOXC10 expression, it was revealed that many genes were upregulated by HOXC10 overexpression. Among them, CST1 was predicted to be a HOXC10 direct target gene via prediction of HOXC10 binding si …
By RNA-sequencing of AGS cells with ectopic HOXC10 expression, it was revealed that many genes were upregulated by HOXC10 …
HOXC10 promotes gastric cancer cell invasion and migration via regulation of the NF-kappaB pathway.
Yao S, He L, Zhang Y, Ye L, Lai Y, Huang L, Wu L, Wu G, Zhu S. Yao S, et al. Biochem Biophys Res Commun. 2018 Jun 27;501(3):628-635. doi: 10.1016/j.bbrc.2018.05.019. Biochem Biophys Res Commun. 2018. PMID: 29753747
Homeobox gene C10 (HOXC10), known to regulate cell differentiation and proliferation, is upregulated in gastric cancer (GC). The mechanism underlying HOXC10 involvement in GC metastasis is unclear. Herein, we found that HOXC10 is overexpressed in GC re …
Homeobox gene C10 (HOXC10), known to regulate cell differentiation and proliferation, is upregulated in gastric cancer (GC). T …
Gene expression analysis of preinvasive and invasive cervical squamous cell carcinomas identifies HOXC10 as a key mediator of invasion.
Zhai Y, Kuick R, Nan B, Ota I, Weiss SJ, Trimble CL, Fearon ER, Cho KR. Zhai Y, et al. Cancer Res. 2007 Nov 1;67(21):10163-72. doi: 10.1158/0008-5472.CAN-07-2056. Cancer Res. 2007. PMID: 17974957
One of the genes up-regulated during progression, HOXC10, was selected for functional studies aimed at assessing its role in mediating invasive behavior of neoplastic squamous epithelial cells. ...Cervical cancer cells with high endogenous levels of HOXC10 we …
One of the genes up-regulated during progression, HOXC10, was selected for functional studies aimed at assessing its role in m …
G-quadruplex structures at the promoter of HOXC10 regulate its expression.
Zhang X, Zhao B, Yan T, Hao A, Gao Y, Li D, Sui G. Zhang X, et al. Biochim Biophys Acta Gene Regul Mech. 2018 Nov;1861(11):1018-1028. doi: 10.1016/j.bbagrm.2018.09.004. Epub 2018 Sep 13. Biochim Biophys Acta Gene Regul Mech. 2018. PMID: 30343692
As a member of the homeobox gene family, HOXC10 plays an important role in cell differentiation and embryonic development of mammals. Increasing evidence also suggests a regulatory role of HOXC10 in oncogenesis, but the regulation of HOXC10 gene …
As a member of the homeobox gene family, HOXC10 plays an important role in cell differentiation and embryonic development of m …
Homeodomain-containing gene 10 inhibits cell apoptosis and promotes cell invasion and migration in osteosarcoma cell lines.
Xiong W, Zhou Q, Liu G, Liu XS, Li XY. Xiong W, et al. Tumour Biol. 2017 May;39(5):1010428317697566. doi: 10.1177/1010428317697566. Tumour Biol. 2017. PMID: 28474998 Free article.
Homeodomain-containing gene 10 (HOXC10) belongs to the homeobox family, which encodes a highly conserved family of transcription factors that plays an important role in morphogenesis in all multicellular organisms. Altered expressions of HOXC10 have been repo …
Homeodomain-containing gene 10 (HOXC10) belongs to the homeobox family, which encodes a highly conserved family of transcripti …
Interleukin 1beta-mediated HOXC10 Overexpression Promotes Hepatocellular Carcinoma Metastasis by Upregulating PDPK1 and VASP.
Dang Y, Chen J, Feng W, Qiao C, Han W, Nie Y, Wu K, Fan D, Xia L. Dang Y, et al. Theranostics. 2020 Feb 19;10(8):3833-3848. doi: 10.7150/thno.41712. eCollection 2020. Theranostics. 2020. PMID: 32206125 Free PMC article.
Luciferase reporter and chromatin immunoprecipitation assays were used to measure the transcriptional regulation of target genes by HOXC10. The effect of HOXC10-mediated invasion and metastasis were analyzed by Transwell assays and by an orthotopic metastasis …
Luciferase reporter and chromatin immunoprecipitation assays were used to measure the transcriptional regulation of target genes by …
Identification of cis-HOX-HOXC10 axis as a therapeutic target for colorectal tumor-initiating cells without APC mutations.
Chen Z, Wu J, Liu B, Zhang G, Wang Z, Zhang L, Wang K, Fan Z, Zhu P. Chen Z, et al. Cell Rep. 2021 Jul 27;36(4):109431. doi: 10.1016/j.celrep.2021.109431. Cell Rep. 2021. PMID: 34320348 Free article.
Mechanistically, cis-HOX binds to HOXC10 mRNA to attenuate its decay through blocking the K-homology splicing regulatory protein (KSRP)-binding sequence of HOXC10 3' UTR. HOXC10 is highly expressed in colorectal tumors and TICs and triggers Wnt/beta-catenin a …
Mechanistically, cis-HOX binds to HOXC10 mRNA to attenuate its decay through blocking the K-homology splicing regulatory protein (KSR …
54 results