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Page 1
Detection of coding microsatellite frameshift mutations in DNA mismatch repair-deficient mouse intestinal tumors.
Woerner SM, Tosti E, Yuan YP, Kloor M, Bork P, Edelmann W, Gebert J. Woerner SM, et al. Mol Carcinog. 2015 Nov;54(11):1376-86. doi: 10.1002/mc.22213. Epub 2014 Sep 11. Mol Carcinog. 2015. PMID: 25213383
A proof-of-principle study was performed to identify mouse cMNR-harboring genes affected by insertion/deletion mutations in MSI murine intestinal tumors. Bioinformatic algorithms were developed to establish a database of mouse cMNR-harboring genes. A panel of five m …
A proof-of-principle study was performed to identify mouse cMNR-harboring genes affected by insertion/deletion mutations in MSI murin …
Standard treatments induce antigen-specific immune responses in prostate cancer.
Nesslinger NJ, Sahota RA, Stone B, Johnson K, Chima N, King C, Rasmussen D, Bishop D, Rennie PS, Gleave M, Blood P, Pai H, Ludgate C, Nelson BH. Nesslinger NJ, et al. Clin Cancer Res. 2007 Mar 1;13(5):1493-502. doi: 10.1158/1078-0432.CCR-06-1772. Clin Cancer Res. 2007. PMID: 17332294
In four patients, SEREX immunoscreening of a prostate cancer cDNA expression library identified several antigens recognized by treatment-associated autoantibodies, including PARP1, ZNF707 + PTMA, CEP78, SDCCAG1, and ODF2. CONCLUSION: We show for the first time that standar …
In four patients, SEREX immunoscreening of a prostate cancer cDNA expression library identified several antigens recognized by treatment-ass …
Drosophila caliban, a nuclear export mediator, can function as a tumor suppressor in human lung cancer cells.
Bi X, Jones T, Abbasi F, Lee H, Stultz B, Hursh DA, Mortin MA. Bi X, et al. Oncogene. 2005 Dec 15;24(56):8229-39. doi: 10.1038/sj.onc.1208962. Oncogene. 2005. PMID: 16103875
Finally, while non-cancerous lung cells have functional Sdccag1, five human lung carcinoma cell lines do not, even though Exportin still functions in these cells. Expression of fly Caliban in these human lung cancer cells restores EYFP-HDA nuclear export, reduces a cell's …
Finally, while non-cancerous lung cells have functional Sdccag1, five human lung carcinoma cell lines do not, even though Exportin st …
Hypomethylation of Alu repetitive elements in esophageal mucosa, and its potential contribution to the epigenetic field for cancerization.
Matsuda Y, Yamashita S, Lee YC, Niwa T, Yoshida T, Gyobu K, Igaki H, Kushima R, Lee S, Wu MS, Osugi H, Suehiro S, Ushijima T. Matsuda Y, et al. Cancer Causes Control. 2012 Jun;23(6):865-73. doi: 10.1007/s10552-012-9955-4. Epub 2012 Apr 19. Cancer Causes Control. 2012. PMID: 22527164
BACKGROUND: Aberrant hypermethylation of specific genes is present in esophageal squamous cell carcinomas (ESCCs). Such hypermethylation is also present in normal-appearing esophageal mucosae of ESCC patients and is considered to contribute to the formation of a field for …
BACKGROUND: Aberrant hypermethylation of specific genes is present in esophageal squamous cell carcinomas (ESCCs). Such hypermethylat …
Characterization of human colon cancer antigens recognized by autologous antibodies.
Scanlan MJ, Chen YT, Williamson B, Gure AO, Stockert E, Gordan JD, Türeci O, Sahin U, Pfreundschuh M, Old LJ. Scanlan MJ, et al. Int J Cancer. 1998 May 29;76(5):652-8. doi: 10.1002/(sici)1097-0215(19980529)76:5<652::aid-ijc7>3.0.co;2-p. Int J Cancer. 1998. PMID: 9610721
In the present study, 48 distinct antigens (NY-CO-1-NY-CO-48) reactive with autologous IgG were identified by SEREX analysis in 4 patients with colon cancer. ...The initial analysis showed NY-CO-13 to be a mutated version of the p53 tumor suppre …
In the present study, 48 distinct antigens (NY-CO-1-NY-CO-48) reactive with autologous IgG were identifie …
Up-regulation of a novel mRNA (NY-CO-1) involved in the methyl 4-methoxy-3-(3-methyl-2-butenoyl) benzoate (VT1)-induced proliferation arrest of a non-small-cell lung carcinoma cell line (NSCLC-N6).
Carbonnelle D, Jacquot C, Lanco X, Le Dez G, Tomasoni C, Briand G, Tsotinis A, Calogeropoulou T, Roussakis C. Carbonnelle D, et al. Int J Cancer. 2001 May 1;92(3):388-97. doi: 10.1002/ijc.1197. Int J Cancer. 2001. PMID: 11291076
Second, we use "differential display" strategy to clarify the genetic mechanisms involved in this proliferation arrest. A novel mRNA, NY-CO-1 (New-York Colon 1), of unknown function showed up-regulated expression after treatment. ...
Second, we use "differential display" strategy to clarify the genetic mechanisms involved in this proliferation arrest. A novel mRNA, NY …