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3,170 results

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Page 1
A Review of Alprazolam Use, Misuse, and Withdrawal.
Ait-Daoud N, Hamby AS, Sharma S, Blevins D. Ait-Daoud N, et al. J Addict Med. 2018 Jan/Feb;12(1):4-10. doi: 10.1097/ADM.0000000000000350. J Addict Med. 2018. PMID: 28777203 Free PMC article. Review.
: Alprazolam is one of the most widely prescribed benzodiazepines for the treatment of generalized anxiety disorder and panic disorder. ...We have replaced it in our manuscript with "misuse liability" as it reflects a more updated terminology consistent with the Diagnostic …
: Alprazolam is one of the most widely prescribed benzodiazepines for the treatment of generalized anxiety disorder and panic disorde …
Alprazolam: Good for Some, Not Good for All!
Mamtani H, Chaturvedi SK. Mamtani H, et al. J Clin Psychopharmacol. 2023 May-Jun 01;43(3):204-208. doi: 10.1097/JCP.0000000000001669. J Clin Psychopharmacol. 2023. PMID: 37040158 Review.
Also, the withdrawal triggered by use of alprazolam is challenging to treat. Alternate pharmacological and non-pharmacological strategies for use in anxiety and insomnia are available, which might be safer than alprazolam. Also, policy changes can serve as an answer …
Also, the withdrawal triggered by use of alprazolam is challenging to treat. Alternate pharmacological and non-pharmacological strate …
Alprazolam and diazepam: addiction potential.
Juergens S. Juergens S. J Subst Abuse Treat. 1991;8(1-2):43-51. doi: 10.1016/0740-5472(91)90026-7. J Subst Abuse Treat. 1991. PMID: 2051498 Review.
Alprazolam and diazepam, the two most prescribed benzodiazepine anxiolytics in the United States, have potential for addictive use. ...Both drugs are rapidly absorbed and enter the brain tissue rapidly, leading to reinforcement. Alprazolam has a shorter half-life, w
Alprazolam and diazepam, the two most prescribed benzodiazepine anxiolytics in the United States, have potential for addictive use. .
Alprazolam is relatively more toxic than other benzodiazepines in overdose.
Isbister GK, O'Regan L, Sibbritt D, Whyte IM. Isbister GK, et al. Br J Clin Pharmacol. 2004 Jul;58(1):88-95. doi: 10.1111/j.1365-2125.2004.02089.x. Br J Clin Pharmacol. 2004. PMID: 15206998 Free PMC article. Review.

AIMS: To describe alprazolam poisoning and the relative toxicity of alprazolam compared with other benzodiazepines. ...Twelve percent of alprazolam overdoses had a GCS < 9 compared with 10% for other benzodiazepines. From benzodiazepine prescription data,

AIMS: To describe alprazolam poisoning and the relative toxicity of alprazolam compared with other benzodiazepines. ...Twelve …
Alprazolam pharmacokinetics, metabolism, and plasma levels: clinical implications.
Greenblatt DJ, von Moltke LL, Harmatz JS, Ciraulo DA, Shader RI. Greenblatt DJ, et al. J Clin Psychiatry. 1993 Oct;54 Suppl:4-11; discussion 12-4. J Clin Psychiatry. 1993. PMID: 8262889 Review.
The triazolobenzodiazepine alprazolam is biotransformed by hepatic microsomal oxidation, yielding two hydroxylated metabolites (4-hydroxy- and a-hydroxy-alprazolam) as the principal metabolic products. Both metabolites have lower benzodiazepine receptor affinity tha …
The triazolobenzodiazepine alprazolam is biotransformed by hepatic microsomal oxidation, yielding two hydroxylated metabolites (4-hyd …
Alprazolam as an antidepressant.
Warner MD, Peabody CA, Whiteford HA, Hollister LE. Warner MD, et al. J Clin Psychiatry. 1988 Apr;49(4):148-50. J Clin Psychiatry. 1988. PMID: 3281931 Review.
Alprazolam appears to be an effective antidepressant in the treatment of outpatients who have a diagnosis of major depressive disorder. ...No satisfactory explanation exists for the mechanism of alprazolam's proposed antidepressant action....
Alprazolam appears to be an effective antidepressant in the treatment of outpatients who have a diagnosis of major depressive disorde
Alprazolam for tinnitus.
Huynh L, Fields S. Huynh L, et al. Ann Pharmacother. 1995 Mar;29(3):311-2. doi: 10.1177/106002809502900313. Ann Pharmacother. 1995. PMID: 7606078 Review.
There is insufficient evidence to support the use of alprazolam in the treatment of tinnitus. The Johnson trial is the only study to date assessing the role of alprazolam, and at best it is an open-label trial demonstrating activity. ...Furthermore, once efficacy is …
There is insufficient evidence to support the use of alprazolam in the treatment of tinnitus. The Johnson trial is the only study to …
Alprazolam-induced hypomania.
Reddy J, Khanna S, Anand U, Banerjee A. Reddy J, et al. Aust N Z J Psychiatry. 1996 Aug;30(4):550-2. doi: 10.3109/00048679609065031. Aust N Z J Psychiatry. 1996. PMID: 8887708
OBJECTIVE: There are reports of alprazolam-induced hypomania/mania. Here is a case report of a patient who developed hypomania during treatment with alprazolam, but not with diazepam, another benzodiazepine derivative. ...Clinicians have to be alert to the possibili …
OBJECTIVE: There are reports of alprazolam-induced hypomania/mania. Here is a case report of a patient who developed hypomania during …
Interaction Risk: Green Tea Consumption in Patients Taking Alprazolam.
Srinivasa DGB, Kadiri SK. Srinivasa DGB, et al. Drug Metab Bioanal Lett. 2024;17(3):104-113. doi: 10.2174/0118723128366248250206081121. Drug Metab Bioanal Lett. 2024. PMID: 40296492 Review.
Numerous bioactive components included in green tea, such as caffeine and catechins, may alter the pharmacokinetics of alprazolam by altering its metabolism, excretion, or absorption. It has been shown that green tea affects the activity of cytochrome P450 enzymes, particu …
Numerous bioactive components included in green tea, such as caffeine and catechins, may alter the pharmacokinetics of alprazolam by …
Alprazolam and benzodiazepine dependence.
Sellers EM, Ciraulo DA, DuPont RL, Griffiths RR, Kosten TR, Romach MK, Woody GE. Sellers EM, et al. J Clin Psychiatry. 1993 Oct;54 Suppl:64-75; discussion 76-7. J Clin Psychiatry. 1993. PMID: 8262891 Review.
In the interim, caution but not prohibition to use should prevail in prescribing alprazolam to such patients. To the extent that nonmedical alprazolam use exists, evidence suggests that the vast majority of such use is the consequence of the inappropriate prescribin …
In the interim, caution but not prohibition to use should prevail in prescribing alprazolam to such patients. To the extent that nonm …
3,170 results