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71 results

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Page 1
Recent advancements in iodide/phosphine-mediated photoredox radical reactions.
Liu T, Zhou Y, Tang J, Wang C. Liu T, et al. Beilstein J Org Chem. 2023 Nov 22;19:1785-1803. doi: 10.3762/bjoc.19.131. eCollection 2023. Beilstein J Org Chem. 2023. PMID: 38033449 Free PMC article. Review.
In this review, we primarily focus on summarizing the recent advancements in inexpensive and readily available iodide/phosphine-mediated photoredox radical transformations....
In this review, we primarily focus on summarizing the recent advancements in inexpensive and readily available iodide/phosphine-media …
Synthesis of (-)-halichonic acid and (-)-halichonic acid B.
Reber KP, Niner EL. Reber KP, et al. Beilstein J Org Chem. 2022 Dec 1;18:1629-1635. doi: 10.3762/bjoc.18.174. eCollection 2022. Beilstein J Org Chem. 2022. PMID: 36530535 Free PMC article.
The first syntheses of the amino acids (-)-halichonic acid and (-)-halichonic acid B have been achieved in ten steps starting from commercially available (-)-alpha-bisabolol. The optimized synthetic route includes a new purification method for isolating (-)-7-amino-7,8-dih …
The first syntheses of the amino acids (-)-halichonic acid and (-)-halichonic acid B have been achieved in ten steps starting from commercia …
Morpholine-mediated defluorinative cycloaddition of gem-difluoroalkenes and organic azides.
Huang TY, Djugovski M, Adhikari S, Manning DL, Roy S. Huang TY, et al. Beilstein J Org Chem. 2023 Oct 5;19:1545-1554. doi: 10.3762/bjoc.19.111. eCollection 2023. Beilstein J Org Chem. 2023. PMID: 37822920 Free PMC article.
Attractive elements include the regioselective and straightforward direct synthesis of fully substituted 1,2,3-triazoles, which are otherwise difficult to access, from readily available starting materials....
Attractive elements include the regioselective and straightforward direct synthesis of fully substituted 1,2,3-triazoles, which are otherwis …
C-H Trifluoromethylthiolation of aldehyde hydrazones.
Levet V, Ramesh B, Wang C, Besset T. Levet V, et al. Beilstein J Org Chem. 2024 Nov 12;20:2883-2890. doi: 10.3762/bjoc.20.242. eCollection 2024. Beilstein J Org Chem. 2024. PMID: 39559444 Free PMC article.
The selective C-H trifluoromethylthiolation of aldehyde hydrazones afforded interesting fluorinated building blocks, which could be used as a synthetic platform. Starting from readily available (hetero)aromatic and aliphatic hydrazones, the formation of a C-SCF(3) bond was …
The selective C-H trifluoromethylthiolation of aldehyde hydrazones afforded interesting fluorinated building blocks, which could be used as …
CuAAC-inspired synthesis of 1,2,3-triazole-bridged porphyrin conjugates: an overview.
Singh DK. Singh DK. Beilstein J Org Chem. 2023 Mar 22;19:349-379. doi: 10.3762/bjoc.19.29. eCollection 2023. Beilstein J Org Chem. 2023. PMID: 36998309 Free PMC article. Review.
Among all the available approaches in organic synthesis, the "click chemistry" protocol is very common nowadays to covalently connect two diverse moieties in a single framework. ...
Among all the available approaches in organic synthesis, the "click chemistry" protocol is very common nowadays to covalently connect …
Photoredox catalysis harvesting multiple photon or electrochemical energies.
Lepori M, Schmid S, Barham JP. Lepori M, et al. Beilstein J Org Chem. 2023 Jul 28;19:1055-1145. doi: 10.3762/bjoc.19.81. eCollection 2023. Beilstein J Org Chem. 2023. PMID: 37533877 Free PMC article. Review.
Nowadays, excellent alternative conditions are available to overcome these limitations, harvesting two different but correlated concepts: the use of multi-photon processes such as consecutive photoinduced electron transfer (conPET) and the combination of photo- and electro …
Nowadays, excellent alternative conditions are available to overcome these limitations, harvesting two different but correlated conce …
New synthesis of a late-stage tetracyclic key intermediate of lumateperone.
Milen M, Nyulasi B, Nagy T, Simig G, Volk B. Milen M, et al. Beilstein J Org Chem. 2022 Jun 10;18:653-659. doi: 10.3762/bjoc.18.66. eCollection 2022. Beilstein J Org Chem. 2022. PMID: 35800146 Free PMC article.
As a result of these efforts, a novel synthesis of the late-stage tetracyclic key intermediate of lumateperone starting from the commercially available quinoxaline is described. The tetracyclic skeleton was constructed by the reaction of 1-trifluoroacetyl-4-aminoquinoxalin …
As a result of these efforts, a novel synthesis of the late-stage tetracyclic key intermediate of lumateperone starting from the commerciall …
Asterics: a simple tool for the ExploRation and Integration of omiCS data.
Maigné É, Noirot C, Henry J, Adu Kesewaah Y, Badin L, Déjean S, Guilmineau C, Krebs A, Mathevet F, Segalini A, Thomassin L, Colongo D, Gaspin C, Liaubet L, Vialaneix N. Maigné É, et al. BMC Bioinformatics. 2023 Oct 18;24(1):391. doi: 10.1186/s12859-023-05504-9. BMC Bioinformatics. 2023. PMID: 37853347 Free PMC article.
Here, we present ASTERICS (version 2.5), a publicly available web interface for the analyses of omics datasets. RESULTS: ASTERICS is designed to make both standard and complex exploratory and integration analysis workflows easily available to biologists and to provi …
Here, we present ASTERICS (version 2.5), a publicly available web interface for the analyses of omics datasets. RESULTS: ASTERICS is …
Nanomedicines against Chagas disease: a critical review.
Morilla MJ, Ghosal K, Romero EL. Morilla MJ, et al. Beilstein J Nanotechnol. 2024 Mar 27;15:333-349. doi: 10.3762/bjnano.15.30. eCollection 2024. Beilstein J Nanotechnol. 2024. PMID: 38590427 Free PMC article. Review.
Chagas disease (CD) is the most important endemic parasitosis in South America and represents a great socioeconomic burden for the chronically ill and their families. The only currently available treatment against CD is based on the oral administration of benznidazole, an …
Chagas disease (CD) is the most important endemic parasitosis in South America and represents a great socioeconomic burden for the chronical …
71 results