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Best clinical practice in botulinum toxin treatment for children with cerebral palsy.
Strobl W, Theologis T, Brunner R, Kocer S, Viehweger E, Pascual-Pascual I, Placzek R. Strobl W, et al. Toxins (Basel). 2015 May 11;7(5):1629-48. doi: 10.3390/toxins7051629. Toxins (Basel). 2015. PMID: 25969944 Free PMC article. Review.
Botulinum toxin A (BoNT-A) is considered a safe and effective therapy for children with cerebral palsy (CP), especially in the hands of experienced injectors and for the majority of children. ...BoNT-A is an important part of multimodal management, to support …
Botulinum toxin A (BoNT-A) is considered a safe and effective therapy for children with cerebral palsy (CP), especially …
The Short-Term Impact of Botulinum Neurotoxin-A on Muscle Morphology and Gait in Children with Spastic Cerebral Palsy.
Peeters N, Papageorgiou E, Hanssen B, De Beukelaer N, Staut L, Degelaen M, Van den Broeck C, Calders P, Feys H, Van Campenhout A, Desloovere K. Peeters N, et al. Toxins (Basel). 2022 Sep 29;14(10):676. doi: 10.3390/toxins14100676. Toxins (Basel). 2022. PMID: 36287944 Free PMC article.
Children with spastic cerebral palsy (SCP) are often treated with intramuscular Botulinum Neurotoxin type-A (BoNT-A). ...Additionally, the effects on gait and spasticity were assessed in all treated children and a subgroup (n = 14), respectively. BoNT-A treatment …
Children with spastic cerebral palsy (SCP) are often treated with intramuscular Botulinum Neurotoxin type-A (BoNT-A). ...Addit …
Effectiveness of Multilevel Botulinum Toxin A Injection with Integrated Treatment Program on Spasticity Reduction in Non-Ambulatory Young Children with Cerebral Palsy.
Aydil S, Akpinar FM, Akpinar E, Beng K, Yagmurlu MF. Aydil S, et al. Med Princ Pract. 2019;28(4):309-314. doi: 10.1159/000499369. Epub 2019 Mar 6. Med Princ Pract. 2019. PMID: 30840957 Free PMC article. Clinical Trial.
OBJECTIVE: The aim of the present study was to evaluate the effectiveness of multilevel Botulinum Toxin A (BTX-A) injection, as part of an integrated approach, for the treatment of spasticity in non-ambulatory young children with diplegic cerebral p …
OBJECTIVE: The aim of the present study was to evaluate the effectiveness of multilevel Botulinum Toxin A (BTX-A) injection, as part of an …
GMFCS level improvement in children with cerebral palsy treated with repeat botulinum toxin injections and intensive rehabilitation: A retrospective study.
Dursun N, Akyuz M, Gokbel T, Akarsu M, Yilmaz E, Karacan C, Dursun E. Dursun N, et al. J Pediatr Rehabil Med. 2022;15(1):107-112. doi: 10.3233/PRM-210013. J Pediatr Rehabil Med. 2022. PMID: 35275571 Free article.
PURPOSE: The Gross Motor Functional Classification System (GMFCS) provides a standardized classification of motor disability in children with cerebral palsy (CP) that is typically considered longitudinally stable. Here, changes in GMFCS levels of children with CP wh …
PURPOSE: The Gross Motor Functional Classification System (GMFCS) provides a standardized classification of motor disability in children wit …
Single event multilevel botulinum toxin type A treatment and surgery: similarities and differences.
Molenaers G, Desloovere K, De Cat J, Jonkers I, De Borre L, Pauwels P, Nijs J, Fabry G, De Cock P. Molenaers G, et al. Eur J Neurol. 2001 Nov;8 Suppl 5:88-97. doi: 10.1046/j.1468-1331.2001.00041.x. Eur J Neurol. 2001. PMID: 11851737
The present study attempts to provide objective evidence of two treatment options for children with cerebral palsy (CP): multilevel botulinum toxin type A (BTX-A) injections and multilevel surgery. ...In conclusion, these treatm …
The present study attempts to provide objective evidence of two treatment options for children with cerebral palsy (CP) …
Mobile digital gait analysis captures effects of botulinum toxin in hereditary spastic paraplegia.
Ibrahim AA, Ollenschläger M, Klebe S, Schüle R, Jeschonneck N, Kellner M, Loris E, Greinwalder T, Eskofier BM, Winkler J, Gaßner H, Regensburger M. Ibrahim AA, et al. Eur J Neurol. 2024 Aug;31(8):e16367. doi: 10.1111/ene.16367. Epub 2024 Jun 10. Eur J Neurol. 2024. PMID: 38859620 Free PMC article.
Botulinum toxin has been approved for lower limb spasticity following stroke and cerebral palsy, but its effects in HSPs remain underexplored. We aimed to characterize the effects of botulinum toxin on clinical, gait, and patient-reported outcomes in HSP patients an …
Botulinum toxin has been approved for lower limb spasticity following stroke and cerebral palsy, but its effects in HSPs remai …
[High doses of botulinum toxin type A in children: efficacy and safety in clinical practice].
Filipetti P, Chantraine F. Filipetti P, et al. Ann Readapt Med Phys. 2007 Jan;50 Suppl 1:S7-S11. doi: 10.1016/s0168-6054(07)80003-1. Ann Readapt Med Phys. 2007. PMID: 17550812 Review. French.
The purpose of this article is to examine the current state of administering high doses botulinum toxin type A for the treatment of childhood spasticity, particularly Cerebral Palsy. ...High doses of botulinum toxin …
The purpose of this article is to examine the current state of administering high doses botulinum toxin type A f …
[Botulinum toxin A in the treatment of infantile cerebral palsy. Taking into account multilevel, integrated treatment].
Molenaers G, Desloovere K, De Cat J. Molenaers G, et al. Orthopade. 2004 Oct;33(10):1119-28. doi: 10.1007/s00132-004-0688-2. Orthopade. 2004. PMID: 15278274 German.
Botulinum toxin A represents a significant development in the management of children and adolescents with spastic cerebral palsy. Prerequisites for an adequate result are a correct indication, an exact injection technique and an intensive post-treatment progr …
Botulinum toxin A represents a significant development in the management of children and adolescents with spastic cerebral palsy …
Functional outcomes of botulinum neurotoxin-A injection followed by reciprocal electrical stimulation in children with cerebral palsy: A randomized controlled trial.
Elnaggar RK, Alqahtani BA, Elbanna MF. Elnaggar RK, et al. Restor Neurol Neurosci. 2020;38(6):431-441. doi: 10.3233/RNN-201088. Restor Neurol Neurosci. 2020. PMID: 33252102 Clinical Trial.
BACKGROUND: The integration of therapeutic approaches is increasingly recommended for children with cerebral palsy, to enhance outcomes. ...Unilateral upper-limb function, bimanual hand function, and real-time arm-hand function were assessed using Melb …
BACKGROUND: The integration of therapeutic approaches is increasingly recommended for children with cerebral palsy …
The evaluation and treatment of elbow dysfunction secondary to spasticity and paralysis.
Barus D, Kozin SH. Barus D, et al. J Hand Ther. 2006 Apr-Jun;19(2):192-205. doi: 10.1197/j.jht.2006.02.012. J Hand Ther. 2006. PMID: 16713867 Review.
An integrated pharmaceutical, surgical, and therapeutic approach is described for the management of patients with spasticity and paralysis of the elbow due to central nervous system injury. The patient populations considered in this article include those with cer …
An integrated pharmaceutical, surgical, and therapeutic approach is described for the management of patients with spasticity a …