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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
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2002 3
2003 1
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2008 3
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2010 4
2011 6
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34 results

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Page 1
APOE in the bullseye of neurodegenerative diseases: impact of the APOE genotype in Alzheimer's disease pathology and brain diseases.
Fernández-Calle R, Konings SC, Frontiñán-Rubio J, García-Revilla J, Camprubí-Ferrer L, Svensson M, Martinson I, Boza-Serrano A, Venero JL, Nielsen HM, Gouras GK, Deierborg T. Fernández-Calle R, et al. Mol Neurodegener. 2022 Sep 24;17(1):62. doi: 10.1186/s13024-022-00566-4. Mol Neurodegener. 2022. PMID: 36153580 Free PMC article. Review.
ApoE is the major lipid and cholesterol carrier in the CNS. There are three major human polymorphisms, apoE2, apoE3, and apoE4, and the genetic expression of APOE4 is one of the most influential risk factors for the development of late-onset Alzheimer's di
ApoE is the major lipid and cholesterol carrier in the CNS. There are three major human polymorphisms, apoE2, apoE3, and apoE4, and t …
Nutrients in Alzheimer's Disease: The Interaction of Diet, Drugs and Disease.
Liyanage SI, Vilekar P, Weaver DF. Liyanage SI, et al. Can J Neurol Sci. 2019 Jan;46(1):23-34. doi: 10.1017/cjn.2018.353. Can J Neurol Sci. 2019. PMID: 30688198 Review.
In recent decades, clinical trials in Alzheimer's disease (AD) have failed at an unprecedented rate. The etiology of AD has since come under renewed scrutiny, both to elucidate the underlying pathologies and to identify novel therapeutic strategies. .. …
In recent decades, clinical trials in Alzheimer's disease (AD) have failed at an unprecedented rate. The etiology
Dietary lipids in the aetiology of Alzheimer's disease: implications for therapy.
Cooper JL. Cooper JL. Drugs Aging. 2003;20(6):399-418. doi: 10.2165/00002512-200320060-00001. Drugs Aging. 2003. PMID: 12710861 Review.
Amyloid plaques and neurofibrillary tangles are the neuropathological hallmarks of Alzheimer's disease (AD), but no conclusive evidence has emerged showing that these hallmarks are the cause and not a product of the disease. ...Interventions involving …
Amyloid plaques and neurofibrillary tangles are the neuropathological hallmarks of Alzheimer's disease (AD), but no con …
Fatty acids as biomodulators of Piezo1 mediated glial mechanosensitivity in Alzheimer's disease.
Ivkovic S, Major T, Mitic M, Loncarevic-Vasiljkovic N, Jovic M, Adzic M. Ivkovic S, et al. Life Sci. 2022 May 15;297:120470. doi: 10.1016/j.lfs.2022.120470. Epub 2022 Mar 10. Life Sci. 2022. PMID: 35283177 Review.
Amyloid plaques, one of the main pathological features of Alzheimer's disease (AD), are substantially harder than the surrounding brain tissue and can activate astrocytes and microglia resulting in the glial engulfment of plaques. ...On the other hand, PUFAs …
Amyloid plaques, one of the main pathological features of Alzheimer's disease (AD), are substantially harder than the s …
Dietary lipids and their oxidized products in Alzheimer's disease.
Corsinovi L, Biasi F, Poli G, Leonarduzzi G, Isaia G. Corsinovi L, et al. Mol Nutr Food Res. 2011 Sep;55 Suppl 2:S161-72. doi: 10.1002/mnfr.201100208. Epub 2011 Aug 31. Mol Nutr Food Res. 2011. PMID: 21954186 Free article. Review.
Alzheimer's disease (AD) is the commonest form of dementia in the elderly, characterized by memory dysfunction, loss of lexical access, spatial and temporal disorientation, and impaired judgment. A growing body of scientific literature addresses the implic
Alzheimer's disease (AD) is the commonest form of dementia in the elderly, characterized by memory dysfunction, loss of
Evaluation of dietary and lifestyle changes as modifiers of S100beta levels in Alzheimer's disease.
D'Cunha NM, McKune AJ, Panagiotakos DB, Georgousopoulou EN, Thomas J, Mellor DD, Naumovski N. D'Cunha NM, et al. Nutr Neurosci. 2019 Jan;22(1):1-18. doi: 10.1080/1028415X.2017.1349032. Epub 2017 Jul 11. Nutr Neurosci. 2019. PMID: 28696163 Review.
There is a significant body of research undertaken in order to elucidate the mechanisms underlying the pathology of Alzheimer's disease (AD), as well as to discover early detection biomarkers and potential therapeutic strategies. ...This review describes the …
There is a significant body of research undertaken in order to elucidate the mechanisms underlying the pathology of Alzheimer's
Copper and iron in Alzheimer's disease: a systematic review and its dietary implications.
Loef M, Walach H. Loef M, et al. Br J Nutr. 2012 Jan;107(1):7-19. doi: 10.1017/S000711451100376X. Epub 2011 Jul 18. Br J Nutr. 2012. PMID: 21767446 Review.
Fe and Cu could represent dietary risk factors for Alzheimer's disease (AD), which has become a global health concern. ...Basic studies and, building on this, clinical investigations are needed to further elucidate in which dietary patterns and …
Fe and Cu could represent dietary risk factors for Alzheimer's disease (AD), which has become a global health co …
Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment.
Halliwell B. Halliwell B. Drugs Aging. 2001;18(9):685-716. doi: 10.2165/00002512-200118090-00004. Drugs Aging. 2001. PMID: 11599635 Review.
Increased levels of oxidative damage to DNA, lipids and proteins have been detected by a range of assays in post-mortem tissues from patients with Parkinson's disease, Alzheimer's disease and amyotrophic lateral sclerosis, and at least some of t …
Increased levels of oxidative damage to DNA, lipids and proteins have been detected by a range of assays in post-mortem tissues from …
[Oxidative stress hypothesis for Alzheimer's disease and its potential therapeutic implications].
Nunomura A. Nunomura A. Rinsho Shinkeigaku. 2013;53(11):1043-5. doi: 10.5692/clinicalneurol.53.1043. Rinsho Shinkeigaku. 2013. PMID: 24291874 Review. Japanese.
Significantly increased levels of oxidized nucleic acids, proteins, and lipids have been described in the brains of subjects with Alzheimer disease (AD) and mild cognitive impairment (MCI) as well as young adults with Down syndrome, compared to age-matched co …
Significantly increased levels of oxidized nucleic acids, proteins, and lipids have been described in the brains of subjects with …
The significance of environmental factors in the etiology of Alzheimer's disease.
Grant WB, Campbell A, Itzhaki RF, Savory J. Grant WB, et al. J Alzheimers Dis. 2002 Jun;4(3):179-89. doi: 10.3233/jad-2002-4308. J Alzheimers Dis. 2002. PMID: 12226537
The proposition that environmental agents, such as diet, aluminum, and viruses, are as important as genetic factors in the etiology of Alzheimer's disease (AD) was advanced by the authors at the Challenging Views of Alzheimer's
The proposition that environmental agents, such as diet, aluminum, and viruses, are as important as genetic factors in the etiolog
34 results