Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1959 1
1960 1
1961 4
1968 1
1969 1
1972 1
1973 3
1974 4
1975 9
1976 5
1977 8
1978 6
1979 7
1980 8
1981 8
1982 4
1983 3
1984 1
1985 3
1986 2
1987 1
1988 3
1989 1
1991 3
1992 3
1993 3
1994 2
1995 3
1996 1
2000 1
2002 2
2003 4
2004 3
2005 4
2006 2
2007 5
2008 4
2009 2
2010 2
2011 2
2012 5
2013 2
2014 1
2015 5
2016 4
2017 3
2018 1
2019 4
2021 3
2022 1
2023 4
2024 4
2025 1
2026 3

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

162 results

Results by year

Filters applied: . Clear all
Page 1
Diphenoxylate and Atropine.
Jain M, Wylie WP. Jain M, et al. 2024 May 1. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–. 2024 May 1. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–. PMID: 32644726 Free Books & Documents.
Diphenoxylate and atropine, a medication combination for managing diarrhea, present a valuable therapeutic option for healthcare professionals. ...This continuing medical education (CME) activity centers on elucidating the indications, action, and contraindications …
Diphenoxylate and atropine, a medication combination for managing diarrhea, present a valuable therapeutic option for healthca …
Diphenoxylate-atropine (Lomotil) overdose in children: an update (report of eight cases and review of the literature).
McCarron MM, Challoner KR, Thompson GA. McCarron MM, et al. Pediatrics. 1991 May;87(5):694-700. Pediatrics. 1991. PMID: 2020516 Review.
Eight pediatric accidental overdoses of diphenoxylate-atropine (Lomotil) are reported, and 28 literature cases are reviewed. This overdose is primarily an opioid intoxication, occasionally associated with atropine toxicity. ...Contrary to popular belief, a …
Eight pediatric accidental overdoses of diphenoxylate-atropine (Lomotil) are reported, and 28 literature cases are reviewed. T …
Determination of diphenoxylate hydrochloride and atropine sulfate in solutions and tablets.
Ballbach RL, Brown DJ, Walters SM. Ballbach RL, et al. J Pharm Sci. 1977 Nov;66(11):1553-6. doi: 10.1002/jps.2600661113. J Pharm Sci. 1977. PMID: 915730
Methods for the determination of diphenoxylate hydrochloride and atropine sulfate combinations in solutions and powdered tablet composites are presented. A semiautomated assay for diphenoxylate hydrochloride in individual tablets (content uniformity) also is …
Methods for the determination of diphenoxylate hydrochloride and atropine sulfate combinations in solutions and powdered table …
Acute effect of diphenoxylate with atropine (Lomotil) in patients with chronic diarrhea and fecal incontinence.
Harford WV, Krejs GJ, Santa Ana CA, Fordtran JS. Harford WV, et al. Gastroenterology. 1980 Mar;78(3):440-3. Gastroenterology. 1980. PMID: 7351282 Clinical Trial.
Fifteen patients with chronic diarrhea and fecal incontinence were admitted to a clinical research center and treated for 3 days with either placebo or diphenoxylate with atropine (Lomotil). The patients were then crossed over to the alternate medication. ...
Fifteen patients with chronic diarrhea and fecal incontinence were admitted to a clinical research center and treated for 3 days with either …
Effect of liquid diphenoxylate hydrochloride and atropine sulfate (Lomotil) instillations on dynamics and function of continent cecal urinary reservoirs.
Fowler JE Jr, Clayton M, Mouli K, Reagan G. Fowler JE Jr, et al. J Urol. 1987 Oct;138(4):735-8. doi: 10.1016/s0022-5347(17)43356-8. J Urol. 1987. PMID: 3656522
We assessed the impact of twice daily instillations of 10 ml. liquid diphenoxylate hydrochloride and atropine sulfate (Lomotil) on the dynamics and function of continent urinary reservoirs constructed from intact cecum and ascending colon. ...No systemic side effect …
We assessed the impact of twice daily instillations of 10 ml. liquid diphenoxylate hydrochloride and atropine sulfate (Lomotil …
Diphenoxylate and pancreatitis.
McCormick PA, O'Donoghue D, Brennan N. McCormick PA, et al. Lancet. 1985 Mar 30;1(8431):752. doi: 10.1016/s0140-6736(85)91287-5. Lancet. 1985. PMID: 2858015 No abstract available.
Determination of diphenoxylate hydrochloride and atropine sulfate in combination drug formulations by liquid chromatography.
Lehr GJ. Lehr GJ. J AOAC Int. 1996 Nov-Dec;79(6):1288-93. J AOAC Int. 1996. PMID: 8946706
An isocratic, reversed-phase liquid chromatographic (LC) method was developed for simultaneous determination of diphenoxylate hydrochloride (I) and atropine sulfate (II) in pharmaceutical products. Analysis is conducted on a Spherisorb CN column (5 microns), with a …
An isocratic, reversed-phase liquid chromatographic (LC) method was developed for simultaneous determination of diphenoxylate hydroch …
Use of atropine-diphenoxylate compared with hyoscyamine to decrease rates of irinotecan-related cholinergic syndrome.
Cheng C, Lau JE, Earl MA. Cheng C, et al. J Community Support Oncol. 2015 Jan;13(1):3-7. doi: 10.12788/jcso.0099. J Community Support Oncol. 2015. PMID: 25839059
OBJECTIVES: To compare the incidence of cholinergic syndrome with irinotecan using atropine-diphenoxylate or hyoscyamine as premedication. METHODS: We conducted a retrospective, single-center, nonrandomized, cohort study of adult patients treated with atro …
OBJECTIVES: To compare the incidence of cholinergic syndrome with irinotecan using atropine-diphenoxylate or hyoscyamine …
Pretreatment with diphenoxylate hydrochloride/atropine sulfate (Lomotil) does not decrease physiologic bowel FDG activity on PET/CT scans of the abdomen and pelvis.
Murphy R, Doerger KM, Nathan MA, Lowe VJ. Murphy R, et al. Mol Imaging Biol. 2009 Mar-Apr;11(2):114-7. doi: 10.1007/s11307-008-0178-8. Epub 2008 Nov 27. Mol Imaging Biol. 2009. PMID: 19037613 Clinical Trial.
We wished to determine if oral administration of the antimotility agent, Lomotil (5 mg diphenoxylate hydrochloride/0.05 mg atropine sulfate; G.D. Searle and Company, a division of Pfizer), prior to PET/CT scanning would reduce physiologic uptake of FDG by the small …
We wished to determine if oral administration of the antimotility agent, Lomotil (5 mg diphenoxylate hydrochloride/0.05 mg atropin …
162 results