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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
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2000 2
2001 1
2002 6
2003 5
2005 5
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2007 9
2008 7
2009 7
2010 4
2011 4
2012 4
2013 10
2014 8
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120 results

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Page 1
Genetics of chronic respiratory disease.
Sayers I, John C, Chen J, Hall IP. Sayers I, et al. Nat Rev Genet. 2024 Aug;25(8):534-547. doi: 10.1038/s41576-024-00695-0. Epub 2024 Mar 6. Nat Rev Genet. 2024. PMID: 38448562 Free PMC article. Review.
Chronic respiratory diseases, such as chronic obstructive pulmonary disease (COPD), asthma and interstitial lung diseases are frequently occurring disorders with a polygenic basis that account for a large global burden of morbidity and mortality. ...Th …
Chronic respiratory diseases, such as chronic obstructive pulmonary disease (COPD), asthma and interstitial lung dis …
Gene-environment interactions in asthma and other respiratory diseases.
Kleeberger SR, Peden D. Kleeberger SR, et al. Annu Rev Med. 2005;56:383-400. doi: 10.1146/annurev.med.56.062904.144908. Annu Rev Med. 2005. PMID: 15660518 Review.
We discuss experimental approaches and challenges that must be overcome to identify disease genes for asthma, COPD and chronic bronchitis, and occupational lung diseases. In particular, common polymorphisms in CD14, glutathione S-transferase, and tumor necrosis fact …
We discuss experimental approaches and challenges that must be overcome to identify disease genes for asthma, COPD and chronic bronch …
Genetic and environmental risk factors for asthma: towards prevention.
Koppelman GH, Pino-Yanes M, Melén E, Powell P, Bracke KR, Celedón JC, Brusselle GG. Koppelman GH, et al. Lancet Respir Med. 2025 Nov;13(11):1011-1025. doi: 10.1016/S2213-2600(25)00256-5. Epub 2025 Sep 29. Lancet Respir Med. 2025. PMID: 41038211 Review.
Asthma is caused by multiple genetic and environmental factors, and possibly their interaction, across the life course. Genetic studies have provided important insights into the pathogenesis, biology, and immunology of asthma, fostering drug discovery. The ro …
Asthma is caused by multiple genetic and environmental factors, and possibly their interaction, across the life course. Geneti …
Gene-environment interactions in childhood asthma revisited; expanding the interaction concept.
Hernandez-Pacheco N, Kere M, Melén E. Hernandez-Pacheco N, et al. Pediatr Allergy Immunol. 2022 May;33(5):e13780. doi: 10.1111/pai.13780. Pediatr Allergy Immunol. 2022. PMID: 35616899 Free PMC article. Review.
Investigation of gene-environment interactions (GxE) may provide important insights into the gene regulatory framework in response to environmental factors of relevance for childhood asthma. Over the years, different methodological strategies ha …
Investigation of gene-environment interactions (GxE) may provide important insights into the gene regulatory fra …
Glutathione S-Transferase Gene Associations and Gene-Environment Interactions for Asthma.
Dai X, Bui DS, Lodge C. Dai X, et al. Curr Allergy Asthma Rep. 2021 May 10;21(5):31. doi: 10.1007/s11882-021-01005-y. Curr Allergy Asthma Rep. 2021. PMID: 33970355 Review.
The GST-environment interaction may depend on exposure type, asthma phenotype or endotype, ethnics, and other complex gene-gene interaction. Future studies could be improved by defining precise asthma endotypes, involving multiple …
The GST-environment interaction may depend on exposure type, asthma phenotype or endotype, ethnics, and other complex …
Precision/Personalized Medicine in Allergic Diseases and Asthma.
Kucuksezer UC, Ozdemir C, Akdis M, Akdis CA. Kucuksezer UC, et al. Arch Immunol Ther Exp (Warsz). 2018 Dec;66(6):431-442. doi: 10.1007/s00005-018-0526-6. Epub 2018 Sep 24. Arch Immunol Ther Exp (Warsz). 2018. PMID: 30251122 Review.
Like many other chronic diseases, every allergic patient has different characteristics based on clinical course, treatment responsiveness and disease outcomes, which are associated with the genetic and epigenetic control of molecular mechanisms and environment. ...I …
Like many other chronic diseases, every allergic patient has different characteristics based on clinical course, treatment responsive …
Differences in asthma genetics between Chinese and other populations.
Leung TF, Ko FW, Sy HY, Tsui SK, Wong GW. Leung TF, et al. J Allergy Clin Immunol. 2014 Jan;133(1):42-8. doi: 10.1016/j.jaci.2013.09.018. Epub 2013 Nov 1. J Allergy Clin Immunol. 2014. PMID: 24188974 Review.
Asthma is caused by complex gene-gene and gene-environment interactions. Most asthma genes are not replicable across populations, which is possibly because of differences in the epidemiology of these genes. ...In conclusion, differ …
Asthma is caused by complex gene-gene and gene-environment interactions. Most asthma genes …
Epigenetics and the Environment in Airway Disease: Asthma and Allergic Rhinitis.
Long A, Bunning B, Sampath V, DeKruyff RH, Nadeau KC. Long A, et al. Adv Exp Med Biol. 2020;1253:153-181. doi: 10.1007/978-981-15-3449-2_6. Adv Exp Med Biol. 2020. PMID: 32445095 Review.
Asthma and rhinitis are complex, heterogeneous diseases characterized by chronic inflammation of the upper and lower airways. ...In allergic airway and other complex diseases, it is thought that epigenetic modifications, including DNA methylation, histone mod …
Asthma and rhinitis are complex, heterogeneous diseases characterized by chronic inflammation of the upper and lower airways. …
Gene by environment interaction in asthma.
London SJ, Romieu I. London SJ, et al. Annu Rev Public Health. 2009;30:55-80. doi: 10.1146/annurev.publhealth.031308.100151. Annu Rev Public Health. 2009. PMID: 18980546 Review.
Marked international differences in rates of asthma and allergies and the importance of family history highlight the primacy of interactions between genetic variation and the environment in asthma etiology. ...Strategies to increase power include coope …
Marked international differences in rates of asthma and allergies and the importance of family history highlight the primacy of in …
Gene-environment interactions in the study of asthma in the postgenomewide association studies era.
Rava M, Smit LA, Nadif R. Rava M, et al. Curr Opin Allergy Clin Immunol. 2015 Feb;15(1):70-8. doi: 10.1097/ACI.0000000000000131. Curr Opin Allergy Clin Immunol. 2015. PMID: 25479314 Free article. Review.
Understanding the mechanisms through which genes and environment interact represents one of the major challenges for pulmonary researchers. This review provides an overview of the recently published literature on gene-environment (G E) interactions i …
Understanding the mechanisms through which genes and environment interact represents one of the major challenges for pulmonary resear …
120 results