Ginkgo biloba for prevention of dementia: a randomized controlled trial.
JAMA. 2008.
PMID: 19017911
Free PMC article.
Clinical Trial.
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Ginkgo biloba for prevention of dementia: a randomized controlled trial.
JAMA. 2008 Nov 19;300(19):2253-62. doi: 10.1001/jama.2008.683.
JAMA. 2008.
PMID: 19017911
Free PMC article.
Clinical Trial.
CONTEXT: Ginkgo biloba is widely used for its potential effects on memory and cognition. To date, adequately powered clinical trials testing the effect of G. biloba on dementia incidence are lacking. ...G. biloba also had no effect on the rate o …
CONTEXT: Ginkgo biloba is widely used for its potential effects on memory and cognition. To date, adequately powered clinical …
A randomized placebo-controlled trial of Ginkgo biloba for the prevention of cognitive decline.
Neurology. 2008 May 6;70(19 Pt 2):1809-17. doi: 10.1212/01.wnl.0000303814.13509.db. Epub 2008 Feb 27.
Neurology. 2008.
PMID: 18305231
Free PMC article.
Clinical Trial.
OBJECTIVE: To assess the feasibility, safety, and efficacy of Ginkgo biloba extract (GBE) on delaying the progression to cognitive impairment in normal elderly aged 85 and older. ...There were more ischemic strokes and TIAs in the GBE group (p = 0.01). CONCLU …
OBJECTIVE: To assess the feasibility, safety, and efficacy of Ginkgo biloba extract (GBE) on delaying the progression t …
Dementia prevention: methodological explanations for inconsistent results.
Epidemiol Rev. 2008;30:35-66. doi: 10.1093/epirev/mxn010. Epub 2008 Sep 8.
Epidemiol Rev. 2008.
PMID: 18779228
Review.
The prevention of neurodegenerative dementias, such as Alzheimer disease, is a growing public health concern, because of a lack of effective curative treatment options and a rising global prevalence. Various potential risk or preventive factors have been sugg …
The prevention of neurodegenerative dementias, such as Alzheimer disease, is a growing public health concern, because of a lac …
The GuidAge study: methodological issues. A 5-year double-blind randomized trial of the efficacy of EGb 761 for prevention of Alzheimer disease in patients over 70 with a memory complaint.
Neurology. 2006 Nov 14;67(9 Suppl 3):S6-11. doi: 10.1212/wnl.67.9_suppl_3.s6.
Neurology. 2006.
PMID: 17101932
Review.
BACKGROUND: Preventive approaches in the field of Alzheimer disease (AD) is important but these trials raise many questions. ...In the past, several studies suggest that Ginkgo biloba could have a potential benefit effect on cognitive function. The aim of the …
BACKGROUND: Preventive approaches in the field of Alzheimer disease (AD) is important but these trials raise many questions. ...In th …
Long-term use of standardised Ginkgo biloba extract for the prevention of Alzheimer's disease (GuidAge): a randomised placebo-controlled trial.
Lancet Neurol. 2012 Oct;11(10):851-9. doi: 10.1016/S1474-4422(12)70206-5. Epub 2012 Sep 6.
Lancet Neurol. 2012.
PMID: 22959217
Review.
We aimed to assess efficacy of long-term use of standardised ginkgo biloba extract for the reduction of incidence of Alzheimer's disease in elderly adults with memory complaints. ...INTERPRETATION: Long-term use of standardised ginkgo biloba …
We aimed to assess efficacy of long-term use of standardised ginkgo biloba extract for the reduction of incidence of Al …
Ginkgo biloba leaf extract: review of biological actions and clinical applications.
Antioxid Redox Signal. 1999 Winter;1(4):469-80. doi: 10.1089/ars.1999.1.4-469.
Antioxid Redox Signal. 1999.
PMID: 11233145
Review.
The number of studies on Ginkgo biloba leaves is rapidly increasing. A variety of effects of Ginkgo biloba leaf extract (GBLE) have been identified. ...GBLE inhibited the increase in the products of the oxidative decomposition low-density lipoprotein ( …
The number of studies on Ginkgo biloba leaves is rapidly increasing. A variety of effects of Ginkgo biloba leaf …
The pharmacologic treatment of Alzheimer's disease: a guide for the general psychiatrist.
Can J Psychiatry. 1998 Sep;43(7):689-97. doi: 10.1177/070674379804300703.
Can J Psychiatry. 1998.
PMID: 9773218
Review.
Key words used in the search were 'randomized controlled trials,' with 'dementia' and with 'Alzheimer's disease'. RESULTS: Agents that are currently available in Canada to treat the cognitive deficits of AD include donepezil, ginkgo biloba, selegiline, and er …
Key words used in the search were 'randomized controlled trials,' with 'dementia' and with 'Alzheimer's disease'. RESULTS: Agents tha …
Drug development for Alzheimer's disease: where are we now and where are we headed?
Am J Geriatr Pharmacother. 2009 Jun;7(3):167-85. doi: 10.1016/j.amjopharm.2009.06.003.
Am J Geriatr Pharmacother. 2009.
PMID: 19616185
Free PMC article.
Review.
METHODS: A search of PubMed to identify pertinent English-language literature was conducted using the terms Alzheimer's disease AND clinical trials (2003-2008), dementia AND prevention AND clinical trials (2003-2008), and the chemical names of all compounds mentione …
METHODS: A search of PubMed to identify pertinent English-language literature was conducted using the terms Alzheimer's disease AND clinical …
The Ginkgo Evaluation of Memory (GEM) study: design and baseline data of a randomized trial of Ginkgo biloba extract in prevention of dementia.
Contemp Clin Trials. 2006 Jun;27(3):238-53. doi: 10.1016/j.cct.2006.02.007. Epub 2006 Apr 19.
Contemp Clin Trials. 2006.
PMID: 16627007
The epidemic of late life dementia, prominence of use of alternative medications and supplements, and initiation of efforts to determine how to prevent dementia have led to efforts to conduct studies aimed at prevention of dementia. The GEM ( …
The epidemic of late life dementia, prominence of use of alternative medications and supplements, and initiation of efforts to determ …
[Ginkgo biloba extract EGb 761 in the treatment of dementia: evidence of efficacy and tolerability].
Fortschr Neurol Psychiatr. 2009 Sep;77(9):494-506. doi: 10.1055/s-0028-1109504. Epub 2009 Jul 20.
Fortschr Neurol Psychiatr. 2009.
PMID: 19621278
Review.
German.
The Ginkgo biloba extract EGb 761 interferes with pathomechanisms relevant to dementia, such as Abeta aggregation, mitochondrial dysfunction, insulin resistance, and hypoperfusion. ...Hence, EGb 761 has its place in the treatment of dementia....
The Ginkgo biloba extract EGb 761 interferes with pathomechanisms relevant to dementia, such as Abeta aggregatio …
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