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45 results

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Guidelines for pharmacotherapy in Alzheimer's disease - A primer on FDA-approved drugs.
Varadharajan A, Davis AD, Ghosh A, Jagtap T, Xavier A, Menon AJ, Roy D, Gandhi S, Gregor T. Varadharajan A, et al. J Neurosci Rural Pract. 2023 Oct-Dec;14(4):566-573. doi: 10.25259/JNRP_356_2023. Epub 2023 Oct 7. J Neurosci Rural Pract. 2023. PMID: 38059250 Free PMC article. Review.
The growing prevalence of dementia makes it important for us to better understand its pathophysiology and treatment modalities, to improve the quality of life of patients and caregivers. Alzheimer's disease (AD), a neurodegenerative disease, is …
The growing prevalence of dementia makes it important for us to better understand its pathophysiology and treatment modalities, to im …
A practical algorithm for managing Alzheimer's disease: what, when, and why?
Cummings JL, Isaacson RS, Schmitt FA, Velting DM. Cummings JL, et al. Ann Clin Transl Neurol. 2015 Mar;2(3):307-23. doi: 10.1002/acn3.166. Epub 2015 Jan 23. Ann Clin Transl Neurol. 2015. PMID: 25815358 Free PMC article. Review.
Alzheimer's disease (AD) is the most common form of dementia and its prevalence is increasing. ...Pharmacologic therapy for AD should be initiated upon diagnosis. All of the currently available cholinesterase inhibitors (ChEIs; don
Alzheimer's disease (AD) is the most common form of dementia and its prevalence is increasing. ...Pharmacologic ther
Diagnosis, management, and treatment of Alzheimer disease: a guide for the internist.
Richards SS, Hendrie HC. Richards SS, et al. Arch Intern Med. 1999 Apr 26;159(8):789-98. doi: 10.1001/archinte.159.8.789. Arch Intern Med. 1999. PMID: 10219924 Review.
Alzheimer disease (AD) is a diagnosis of inclusion based on patient history, physical examination, neuropsychological testing, and laboratory studies; however, there is no definitive diagnostic test for AD. ...Other cholinesterase inhibitors are in dev
Alzheimer disease (AD) is a diagnosis of inclusion based on patient history, physical examination, neuropsychological testing,
Primary Palliative Care in Dementia.
Weisbrod N. Weisbrod N. Neurotherapeutics. 2022 Jan;19(1):143-151. doi: 10.1007/s13311-021-01171-x. Epub 2022 Jan 26. Neurotherapeutics. 2022. PMID: 35080735 Free PMC article. Review.
Excellent primary palliative care also involves discussion of deprescribing medications of uncertain benefit such as long term use of cholinesterase inhibitors and memantine and being vigilant in the monitoring of pain with its relationship to behavioral dist …
Excellent primary palliative care also involves discussion of deprescribing medications of uncertain benefit such as long term use of cho
Psychiatric Adverse Events of Acetylcholinesterase Inhibitors in Alzheimer's Disease and Parkinson's Dementia: Systematic Review and Meta-Analysis.
Bittner N, Funk CSM, Schmidt A, Bermpohl F, Brandl EJ, Algharably EEA, Kreutz R, Riemer TG. Bittner N, et al. Drugs Aging. 2023 Nov;40(11):953-964. doi: 10.1007/s40266-023-01065-x. Epub 2023 Sep 8. Drugs Aging. 2023. PMID: 37682445 Free PMC article.
METHODS: We sought to determine the risk of psychiatric adverse events associated with the use of AChEIs through a systematic review and meta-analysis of double-blind randomized controlled trials involving patients with Alzheimer's dementia and Parkinson's dementia. …
METHODS: We sought to determine the risk of psychiatric adverse events associated with the use of AChEIs through a systematic review and met …
Initiating and monitoring cholinesterase inhibitor treatment for Alzheimer's disease.
Swanwick GR, Lawlor BA. Swanwick GR, et al. Int J Geriatr Psychiatry. 1999 Apr;14(4):244-8. doi: 10.1002/(sici)1099-1166(199904)14:4<244::aid-gps917>3.0.co;2-o. Int J Geriatr Psychiatry. 1999. PMID: 10340182
The availability of acetylcholinesterase inhibitors for the treatment of Alzheimer's disease raises a number of clinical and ethical questions. ...Instead the primary care physician should refer potentially suitable patients for specialist asses …
The availability of acetylcholinesterase inhibitors for the treatment of Alzheimer's disease raises a num …
Assessment of treatment-associated changes in behavior and cholinergic therapy of neuropsychiatric symptoms in Alzheimer's disease.
Cummings JL, Masterman DL. Cummings JL, et al. J Clin Psychiatry. 1998;59 Suppl 13:23-30. J Clin Psychiatry. 1998. PMID: 9771827 Review.
Alzheimer's disease affects multiple domains of human brain function and has neuropsychological, neuropsychiatric, and neurologic manifestations. ...Cholinergic therapies ameliorate behavioral alteration in Alzheimer's disease, and change
Alzheimer's disease affects multiple domains of human brain function and has neuropsychological, neuropsychiatric, and
Effective pharmacologic management of Alzheimer's disease.
Farlow MR, Cummings JL. Farlow MR, et al. Am J Med. 2007 May;120(5):388-97. doi: 10.1016/j.amjmed.2006.08.036. Am J Med. 2007. PMID: 17466645 Review.
Cholinesterase inhibitor therapy with rivastigmine, donepezil, or galantamine is endorsed as standard first-line therapy in patients with mild-to-moderate Alzheimer's disease. The N-methyl-D-aspartate receptor-antagonist, memantine
Cholinesterase inhibitor therapy with rivastigmine, donepezil, or galantamine is endorsed as standard first-line the
The Use of Cholinesterase Inhibitors Across All Stages of Alzheimer's Disease.
Deardorff WJ, Feen E, Grossberg GT. Deardorff WJ, et al. Drugs Aging. 2015 Jul;32(7):537-47. doi: 10.1007/s40266-015-0273-x. Drugs Aging. 2015. PMID: 26033268 Review.
Current pharmacological therapy for Alzheimer's disease (AD) includes the cholinesterase inhibitors (ChEIs) donepezil, rivastigmine, and galantamine and the N-methyl D-aspartate receptor antagonist memantine. ...While side effects are gen …
Current pharmacological therapy for Alzheimer's disease (AD) includes the cholinesterase inhibitors
Plasma Myeloperoxidase as a Potential Biomarker of Patient Response to Anti-Dementia Treatment in Alzheimer's Disease.
Wright JR, Deen QFE, Stevenson A, Telford-Cooke LL, Parker C, Martin-Ruiz C, Steinert JR, Kalaria RN, Mukaetova-Ladinska EB. Wright JR, et al. J Alzheimers Dis. 2022;89(4):1483-1492. doi: 10.3233/JAD-220642. J Alzheimers Dis. 2022. PMID: 36057826
BACKGROUND: Myeloperoxidase (MPO), a neutrophil-derived pro-inflammatory protein, co-localizes with amyloid-beta (Abeta) plaques in Alzheimer's disease (AD). Anti-dementia treatment may facilitate efflux of Abeta and associated plaque proteins from the …
BACKGROUND: Myeloperoxidase (MPO), a neutrophil-derived pro-inflammatory protein, co-localizes with amyloid-beta (Abeta) plaques in Alzhe
45 results