Neuroadaptations involved in amphetamine and cocaine addiction.
Drug Alcohol Depend. 1998.
PMID: 9716936
Review.
No abstract available.
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Neuroadaptations involved in amphetamine and cocaine addiction.
Drug Alcohol Depend. 1998 Jun-Jul;51(1-2):141-53. doi: 10.1016/s0376-8716(98)00072-6.
Drug Alcohol Depend. 1998.
PMID: 9716936
Review.
No abstract available.
The role of serotonin in drug use and addiction.
Behav Brain Res. 2015 Jan 15;277:146-92. doi: 10.1016/j.bbr.2014.04.007. Epub 2014 Apr 25.
Behav Brain Res. 2015.
PMID: 24769172
Review.
Here we review the role of the serotonergic (5-HT) system in the establishment of drug use-associated behaviours on the one hand and the transition and maintenance of addiction on the other hand for the drugs: cocaine, amphetamine, methamphetamine, MDMA (ecst …
Here we review the role of the serotonergic (5-HT) system in the establishment of drug use-associated behaviours on the one hand and the tra …
Periadolescent mice show enhanced DeltaFosB upregulation in response to cocaine and amphetamine.
J Neurosci. 2002 Nov 1;22(21):9155-9. doi: 10.1523/JNEUROSCI.22-21-09155.2002.
J Neurosci. 2002.
PMID: 12417638
Free PMC article.
Despite the widespread use of psychomotor stimulants in younger age groups, little is known regarding the chronic molecular neuroadaptive responses to these agents in the immature brain. Here we demonstrate that, after chronic administration of the psychostimulants coca …
Despite the widespread use of psychomotor stimulants in younger age groups, little is known regarding the chronic molecular neuroadaptive …
The role of fibroblast growth factor 2 in drug addiction.
Eur J Neurosci. 2019 Aug;50(3):2552-2561. doi: 10.1111/ejn.14133. Epub 2018 Sep 12.
Eur J Neurosci. 2019.
PMID: 30144335
Review.
Over the past decade, FGF2 has been implicated in learning and memory, as well as in several neuropsychiatric disorders, including anxiety, stress, depression and drug addiction. In this review, we present accumulating evidence indicating the involvement of F …
Over the past decade, FGF2 has been implicated in learning and memory, as well as in several neuropsychiatric disorders, including an …
The neurobiology of drug addiction.
J Neuropsychiatry Clin Neurosci. 1997 Summer;9(3):482-97. doi: 10.1176/jnp.9.3.482.
J Neuropsychiatry Clin Neurosci. 1997.
PMID: 9276849
Review.
Animals models have begun to provide insights into the neurobiological basis of reinforcement in drug addiction. The reinforcing effects of indirect sympathomimetics such as cocaine and amphetamine appear to depend on release of dopamine in the terminal field …
Animals models have begun to provide insights into the neurobiological basis of reinforcement in drug addiction. The reinforcing effe …
Cannabidiol Treatment Might Promote Resilience to Cocaine and Methamphetamine Use Disorders: A Review of Possible Mechanisms.
Molecules. 2019 Jul 16;24(14):2583. doi: 10.3390/molecules24142583.
Molecules. 2019.
PMID: 31315244
Free PMC article.
Review.
Currently, there are no approved pharmacotherapies for addiction to cocaine and other psychostimulant drugs. Several studies have proposed that cannabidiol (CBD) could be a promising treatment for substance use disorders. ...Observational studies suggest that …
Currently, there are no approved pharmacotherapies for addiction to cocaine and other psychostimulant drugs. Several studies h …
Alterations in dopaminergic and glutamatergic transmission in the induction and expression of behavioral sensitization: a critical review of preclinical studies.
Psychopharmacology (Berl). 2000 Aug;151(2-3):99-120. doi: 10.1007/s002130000493.
Psychopharmacology (Berl). 2000.
PMID: 10972458
Review.
This phenomenon, termed behavioral sensitization, is thought to underlie certain aspects of drug addiction. Behavioral sensitization is the consequence of drug-induced neuroadaptive changes in a circuit involving dopaminergic and glutamatergic interconnection …
This phenomenon, termed behavioral sensitization, is thought to underlie certain aspects of drug addiction. Behavioral sensitization …
Group III metabotropic glutamate receptors and drug addiction.
Front Med. 2013 Dec;7(4):445-51. doi: 10.1007/s11684-013-0291-1.
Front Med. 2013.
PMID: 24078068
Free PMC article.
Review.
Neuroadaptations of glutamatergic transmission in the limbic reward circuitry are linked to persistent drug addiction. ...In response to operant administration of common addictive drugs, such as psychostimulants (cocaine and amphetamine), alcohol and o …
Neuroadaptations of glutamatergic transmission in the limbic reward circuitry are linked to persistent drug addiction. ...In r …
New insights into the roles of microRNAs in drug addiction and neuroplasticity.
Genome Med. 2010 Dec 23;2(12):92. doi: 10.1186/gm213.
Genome Med. 2010.
PMID: 21205279
Free PMC article.
Psychostimulants (such as cocaine, heroin and amphetamines) induce strong and persistent neuroadaptive changes through a surfeit of gene regulatory mechanisms leading to addiction. ...They also act as key spatiotemporal regulators during dendritic morp …
Psychostimulants (such as cocaine, heroin and amphetamines) induce strong and persistent neuroadaptive changes through …
Role of oxytocin in the neuroadaptation to drugs of abuse.
Psychoneuroendocrinology. 1994;19(1):85-117. doi: 10.1016/0306-4530(94)90062-0.
Psychoneuroendocrinology. 1994.
PMID: 9210215
Review.
Behavioral tolerance to cocaine was also attenuated by OXT. On the contrary, OXT stimulated the development of behavioral sensitization to cocaine. ...Both morphine tolerance and dependence, and cocaine administration, increased dopamine utilization in the me …
Behavioral tolerance to cocaine was also attenuated by OXT. On the contrary, OXT stimulated the development of behavioral sensitizati …
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