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103 results

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A Path to Improved Alzheimer's Care: Simulating Long-Term Health Outcomes of Lecanemab in Early Alzheimer's Disease from the CLARITY AD Trial.
Tahami Monfared AA, Ye W, Sardesai A, Folse H, Chavan A, Aruffo E, Zhang Q. Tahami Monfared AA, et al. Neurol Ther. 2023 Jun;12(3):863-881. doi: 10.1007/s40120-023-00473-w. Epub 2023 Apr 2. Neurol Ther. 2023. PMID: 37009976 Free PMC article.
INTRODUCTION: Alzheimer's disease (AD), a progressive neurodegenerative disease, is the main cause of dementia and one of the leading causes of death for elderly people in the USA. ...CONCLUSION: The study findings demonstrate the potential clinical …
INTRODUCTION: Alzheimer's disease (AD), a progressive neurodegenerative disease, is the main cause of dementia a …
The Value of Delaying Alzheimer's Disease Onset.
Zissimopoulos J, Crimmins E, St Clair P. Zissimopoulos J, et al. Forum Health Econ Policy. 2014 Nov;18(1):25-39. doi: 10.1515/fhep-2014-0013. Epub 2014 Nov 4. Forum Health Econ Policy. 2014. PMID: 27134606 Free PMC article.
Alzheimer's disease (AD) extracts a heavy societal toll. The value of medical advances that delay onset of AD could be significant. ...We find Medical advances delaying onset of AD generate significant economic and longevity
Alzheimer's disease (AD) extracts a heavy societal toll. The value of medical advances that delay onse
Modelling the Pan-European Economic Burden of Alzheimer's Disease.
Martins R, Urbich M, Brännvall K, Gianinazzi M, Ching JE, Khoury CP, El-Hayek YH. Martins R, et al. JAR Life. 2022 Nov 15;11:38-46. doi: 10.14283/jarlife.2022.7. eCollection 2022. JAR Life. 2022. PMID: 36923231 Free PMC article.
BACKGROUND: Recent advances open the opportunity of altering the course of Alzheimer's disease (AD) through lifestyle-based modifications and novel therapies. Ensuring that society is investing limited budgets in the interventions that have the greatest poten …
BACKGROUND: Recent advances open the opportunity of altering the course of Alzheimer's disease (AD) through lifestyle-b …
Something Is Better Than Nothing: The Value of Active Intervention in Stated Preferences for Treatments to Delay Onset of Alzheimer's Disease Symptoms.
Johnson FR, DiSantostefano RL, Yang JC, Reed SD, Streffer J, Levitan B. Johnson FR, et al. Value Health. 2019 Sep;22(9):1063-1069. doi: 10.1016/j.jval.2019.03.022. Epub 2019 Jul 20. Value Health. 2019. PMID: 31511183 Free article.
BACKGROUND: The objective of the study was to understand respondents' willingness to accept hypothetical treatment-related risks in return for the benefit of additional time with normal memory from potential Alzheimer's disease interception therapies. METHODS …
BACKGROUND: The objective of the study was to understand respondents' willingness to accept hypothetical treatment-related risks in return f …
Amla Therapy as a Potential Modulator of Alzheimer's Disease Risk Factors and Physiological Change.
Teimouri E, Rainey-Smith SR, Bharadwaj P, Verdile G, Martins RN. Teimouri E, et al. J Alzheimers Dis. 2020;74(3):713-733. doi: 10.3233/JAD-191033. J Alzheimers Dis. 2020. PMID: 32083581 Review.
There is currently no effective treatment for Alzheimer's disease (AD), the most common form of dementia. It has been proposed, however, that a modest delay in onset can significantly reduce the number of cases. ...Collectively, this evidence su …
There is currently no effective treatment for Alzheimer's disease (AD), the most common form of dementia. It has been p …
gamma-Secretase activity, clinical features, and biomarkers of autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analysis of the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS).
Schultz SA, Liu L, Schultz AP, Fitzpatrick CD, Levin R, Bellier JP, Shirzadi Z, Joseph-Mathurin N, Chen CD, Benzinger TLS, Day GS, Farlow MR, Gordon BA, Hassenstab JJ, Jack CR Jr, Jucker M, Karch CM, Lee JH, Levin J, Perrin RJ, Schofield PR, Xiong C, Johnson KA, McDade E, Bateman RJ, Sperling RA, Selkoe DJ, Chhatwal JP; Dominantly Inherited Alzheimer Network. Schultz SA, et al. Lancet Neurol. 2024 Sep;23(9):913-924. doi: 10.1016/S1474-4422(24)00236-9. Epub 2024 Jul 26. Lancet Neurol. 2024. PMID: 39074479
BACKGROUND: Genetic variants that cause autosomal dominant Alzheimer's disease are highly penetrant but vary substantially regarding age at symptom onset (AAO), rates of cognitive decline, and biomarker changes. Most pathogenic variants that cau …
BACKGROUND: Genetic variants that cause autosomal dominant Alzheimer's disease are highly penetrant but vary substantia …
The Comparison of Oropharyngeal Dysphagia in Alzheimer's Disease versus Older Adults with Presbyphagia.
Tanrıverdi M, Osmanoğlu E, Gelişin Ö, Çalım ÖF, Soysal P. Tanrıverdi M, et al. Dysphagia. 2024 Oct 30. doi: 10.1007/s00455-024-10777-0. Online ahead of print. Dysphagia. 2024. PMID: 39476095
Aging is a well-known risk factor for Alzheimer's disease (AD), and oropharyngeal dysphagia (OD) is a common condition in AD. ...Evaluation of swallowing disorders after diagnosis is essential for both AD and OAwP. Early-stage management of disease wit …
Aging is a well-known risk factor for Alzheimer's disease (AD), and oropharyngeal dysphagia (OD) is a common condition …
Correlation of Alzheimer's disease death rates with historical per capita personal income in the USA.
Stępkowski D, Woźniak G, Studnicki M. Stępkowski D, et al. PLoS One. 2015 May 11;10(5):e0126139. doi: 10.1371/journal.pone.0126139. eCollection 2015. PLoS One. 2015. PMID: 25961738 Free PMC article.
Alzheimer's disease (AD) is a progressive degenerating disease of complex etiology. A variety of risk factors contribute to the chance of developing AD. ...From 1929 to 2005 the R value varies in an oscillatory manner, with the strongest correla
Alzheimer's disease (AD) is a progressive degenerating disease of complex etiology. A variety of risk factors co
Integrating amyloid imaging and genetics for early risk stratification of Alzheimer's disease.
He B, Wu R, Sangani N, Pugalenthi PV, Patania A, Risacher SL, Nho K, Apostolova LG, Shen L, Saykin AJ, Yan J; Alzheimer's Disease Neuroimaging Initiative. He B, et al. Alzheimers Dement. 2024 Nov;20(11):7819-7830. doi: 10.1002/alz.14244. Epub 2024 Sep 17. Alzheimers Dement. 2024. PMID: 39285750 Free PMC article.
INTRODUCTION: Alzheimer's disease (AD) initiates years prior to symptoms, underscoring the importance of early detection. ...RESULTS: Our risk score outperformed amyloid composite standardized uptake value ratio in correlation with cognitive scores. MC …
INTRODUCTION: Alzheimer's disease (AD) initiates years prior to symptoms, underscoring the importance of early detectio …
Biomarkers in Alzheimer's disease drug development.
Cummings JL. Cummings JL. Alzheimers Dement. 2011 May;7(3):e13-44. doi: 10.1016/j.jalz.2010.06.004. Epub 2011 May 6. Alzheimers Dement. 2011. PMID: 21550318 Review.
Developing new therapies for Alzheimer's disease (AD) is critically important to avoid the impending public health disaster imposed by this common disorder. Means must be found to prevent, delay the onset, or slow the progression of AD. These go …
Developing new therapies for Alzheimer's disease (AD) is critically important to avoid the impending public health disa …
103 results