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Year Number of Results
1875 2
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1947 1
1949 2
1951 1
1952 1
1953 2
1955 1
1956 2
1957 2
1958 1
1959 2
1960 2
1961 1
1962 3
1963 1
1964 1
1965 2
1966 2
1968 1
1970 1
1973 1
1977 2
1981 1
1983 1
1984 1
1985 1
1986 1
1987 2
1988 4
1989 1
1990 1
1991 3
1992 2
1993 4
1994 3
1995 2
1996 4
1997 5
1998 1
1999 1
2000 4
2001 3
2002 7
2003 10
2004 4
2005 4
2006 5
2007 10
2008 8
2009 7
2010 6
2011 10
2012 8
2013 11
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Quoted phrases not found in phrase index: "(10S)-10-glucopyranosyl-1,8-dihydroxy- 3-(hydroxymethyl)-9(10H)-anthracenone", "(1S)-1,5-anhydro-1-[(9R)-4,5-dihydroxy-2-(hydroxymethyl)-10-oxo-9,10-dihydroanthracen-9-yl]-D-glucitol"
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Pharmacological Update Properties of Aloe Vera and its Major Active Constituents.
Sánchez M, González-Burgos E, Iglesias I, Gómez-Serranillos MP. Sánchez M, et al. Molecules. 2020 Mar 13;25(6):1324. doi: 10.3390/molecules25061324. Molecules. 2020. PMID: 32183224 Free PMC article. Review.
Research on this medicinal plant has been aimed at validating traditional uses and deepening the mechanism of action, identifying the compounds responsible for these activities. The most investigated active compounds are aloe-emodin, aloin, aloesin, emodin, and acemannan. …
Research on this medicinal plant has been aimed at validating traditional uses and deepening the mechanism of action, identifying the compou …
Non-pharmacologic approach to pediatric constipation.
Santucci NR, Chogle A, Leiby A, Mascarenhas M, Borlack RE, Lee A, Perez M, Russell A, Yeh AM. Santucci NR, et al. Complement Ther Med. 2021 Jun;59:102711. doi: 10.1016/j.ctim.2021.102711. Epub 2021 Mar 15. Complement Ther Med. 2021. PMID: 33737146 Free article. Review.
Other than senna, studies of botanicals indicate significant safety concerns (in particular with Aloe vera with aloin and Cascara sagrada) and insufficient evidence. For patients with a significant behavioral or anxiety component to their FC and exhibit dyssynergia, mind-b …
Other than senna, studies of botanicals indicate significant safety concerns (in particular with Aloe vera with aloin and Cascara sag …
Aloin suppresses lipopolysaccharide-induced inflammation by inhibiting JAK1-STAT1/3 activation and ROS production in RAW264.7 cells.
Ma Y, Tang T, Sheng L, Wang Z, Tao H, Zhang Q, Zhang Y, Qi Z. Ma Y, et al. Int J Mol Med. 2018 Oct;42(4):1925-1934. doi: 10.3892/ijmm.2018.3796. Epub 2018 Jul 31. Int J Mol Med. 2018. PMID: 30066904 Free PMC article.
The anti-inflammatory effects of aloin, a bioactive ingredient extracted from Aloe vera, have been described previously. ...Mechanistically, aloin suppressed LPS-induced JAK1-STAT1/3 activation and STAT1/3 nuclear translocation. ...
The anti-inflammatory effects of aloin, a bioactive ingredient extracted from Aloe vera, have been described previously. ...Mechanist …
Integrating Network Pharmacology and Experimental Verification to Explore the Pharmacological Mechanisms of Aloin Against Gastric Cancer.
Gao J, Yang S, Xie G, Pan J, Zhu F. Gao J, et al. Drug Des Devel Ther. 2022 Jun 20;16:1947-1961. doi: 10.2147/DDDT.S360790. eCollection 2022. Drug Des Devel Ther. 2022. PMID: 35757520 Free PMC article.
The results also showed that Aloin could decrease the mRNA and protein expressions of PI3K and AKT, suggesting that Aloin can treat GC by inducing cell apoptosis and regulating the PI3K-AKT signaling pathway. CONCLUSION: This study identified the potential targets o …
The results also showed that Aloin could decrease the mRNA and protein expressions of PI3K and AKT, suggesting that Aloin can …
Barbaloin attenuates pulmonary fibrosis through TGF-beta1/Smads/p38 pathway.
Zhang G, Bai R, Huang J, Gao Y, Yun X, Haji AA. Zhang G, et al. J Pharm Pharmacol. 2022 Aug 19;74(8):1160-1169. doi: 10.1093/jpp/rgac023. J Pharm Pharmacol. 2022. PMID: 35666278
OBJECTIVES: Barbaloin is one of the main bioactive ingredients extracted from Aloe vera, which has the property of protecting the lung from LPS-induced acute injury; however, the anti-pulmonary fibrosis effect of barbaloin is still unknown. ...CONCLUSIONS: Our findi …
OBJECTIVES: Barbaloin is one of the main bioactive ingredients extracted from Aloe vera, which has the property of protecting the lun …
Can aloin develop to medicines or healthcare products?
Yang Y, Wu JJ, Xia J, Wan Y, Xu JF, Zhang L, Liu D, Chen L, Tang F, Ao H, Peng C. Yang Y, et al. Biomed Pharmacother. 2022 Sep;153:113421. doi: 10.1016/j.biopha.2022.113421. Epub 2022 Aug 6. Biomed Pharmacother. 2022. PMID: 36076485 Free article. Review.
Therefore, developing related products of the active ingredients derived from Aloe is of great medical value. Aloin is a quality standard compound based on the Chinese Pharmacopoeia (CHP). ...Moreover, significant attention had been paid to the development of aloin- …
Therefore, developing related products of the active ingredients derived from Aloe is of great medical value. Aloin is a quality stan …
Barbaloin inhibits ventricular arrhythmias in rabbits by modulating voltage-gated ion channels.
Cao ZZ, Tian YJ, Hao J, Zhang PH, Liu ZP, Jiang WZ, Zeng ML, Zhang PP, Ma JH. Cao ZZ, et al. Acta Pharmacol Sin. 2018 Mar;39(3):357-370. doi: 10.1038/aps.2017.93. Epub 2017 Oct 26. Acta Pharmacol Sin. 2018. PMID: 29072259 Free PMC article.
Here, we investigated the effects of barbaloin on cardiac electrophysiology, which has not been reported thus far. ...These results demonstrate that barbaloin has potential as an antiarrhythmic drug....
Here, we investigated the effects of barbaloin on cardiac electrophysiology, which has not been reported thus far. ...These results d …
Barbaloin: a concise report of its pharmacological and analytical aspects.
Patel DK, Patel K, Tahilyani V. Patel DK, et al. Asian Pac J Trop Biomed. 2012 Oct;2(10):835-8. doi: 10.1016/S2221-1691(12)60239-1. Asian Pac J Trop Biomed. 2012. PMID: 23569857 Free PMC article. Review.
The peak amount of barbaloin was reached about 3 h after oral administration. Concentration of barbaloin in Aloe vera leaves was shown to depend on the leaf part, age, and position of the leaf. Young leaves contain more barbaloin compared to old one. Various …
The peak amount of barbaloin was reached about 3 h after oral administration. Concentration of barbaloin in Aloe vera leaves w …
Self-assembled 4-(1,2-diphenylbut-1-en-1-yl)aniline based nanoparticles: podophyllotoxin and aloin as building blocks.
Fumagalli G, Christodoulou MS, Riva B, Revuelta I, Marucci C, Collico V, Prosperi D, Riva S, Perdicchia D, Bassanini I, García-Argáez A, Via LD, Passarella D. Fumagalli G, et al. Org Biomol Chem. 2017 Feb 1;15(5):1106-1109. doi: 10.1039/c6ob02591a. Org Biomol Chem. 2017. PMID: 28093593
The ability of 4-(1,2-diphenylbut-1-en-1-yl)aniline as a self-assembly inducer is reported. The conjugation of this moiety with aloin or podophyllotoxin resulted in spherical nanoparticles that were characterized by Dynamic Light Scattering (DLS), Transmission Electron Mic …
The ability of 4-(1,2-diphenylbut-1-en-1-yl)aniline as a self-assembly inducer is reported. The conjugation of this moiety with aloin
The potential health benefits of aloin from genus Aloe.
Xiao J, Chen S, Chen Y, Su J. Xiao J, et al. Phytother Res. 2022 Feb;36(2):873-890. doi: 10.1002/ptr.7371. Epub 2022 Jan 17. Phytother Res. 2022. PMID: 35040198 Review.
Aloin has attracted considerable interest for its antiinflammatory, anticancer, antibacterial, and antioxidant activities. ...Herein, we summarized the sources and potential health benefits of aloin from a clinical application perspective to guide for further studie
Aloin has attracted considerable interest for its antiinflammatory, anticancer, antibacterial, and antioxidant activities. ...Herein,
371 results