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Page 1
Microbial Routes to (2R,3R)-2,3-Butanediol: Recent Advances and Future Prospects.
Xie NZ, Chen XR, Wang QY, Chen D, Du QS, Zhou GP, Huang RB. Xie NZ, et al. Curr Top Med Chem. 2017;17(21):2433-2439. doi: 10.2174/1568026617666170504101646. Curr Top Med Chem. 2017. PMID: 28474550 Review.
(2R,3R)-2,3-Butanediol has many industrial applications, such as it is used as an antifreeze agent and low freezing point fuel. ...In recent years, this valuable bio-based chemical has attracted increasing attention, and significant progress has …
(2R,3R)-2,3-Butanediol has many industrial applications, such as it is used as an antifreeze agent and lo …
2,3-Butanediol catabolism in Pseudomonas aeruginosa PAO1.
Liu Q, Liu Y, Kang Z, Xiao D, Gao C, Xu P, Ma C. Liu Q, et al. Environ Microbiol. 2018 Nov;20(11):3927-3940. doi: 10.1111/1462-2920.14332. Epub 2018 Sep 24. Environ Microbiol. 2018. PMID: 30058099
In this study, we investigated whether and how P. aeruginosa PAO1 utilizes these 2,3-BD stereoisomers and showed that all three stereoisomers were transformed into acetoin by (2R,3R)-2,3-butanediol dehydrogenase (BDH) or (2S,3S)-2,3-BDH. Acetoin …
In this study, we investigated whether and how P. aeruginosa PAO1 utilizes these 2,3-BD stereoisomers and showed that all three stereoisomer …
Characterization of a (2R,3R)-2,3-Butanediol Dehydrogenase from Rhodococcus erythropolis WZ010.
Yu M, Huang M, Song Q, Shao J, Ying X. Yu M, et al. Molecules. 2015 Apr 20;20(4):7156-73. doi: 10.3390/molecules20047156. Molecules. 2015. PMID: 25903366 Free PMC article.
Kinetic parameters of the enzyme showed lower Km values and higher catalytic efficiency for diacetyl and NADH in comparison to those for (2R,3R)-2,3-butanediol and NAD+. The activity of acetoin reduction was 7.7 times higher than that of (2R …
Kinetic parameters of the enzyme showed lower Km values and higher catalytic efficiency for diacetyl and NADH in comparison to those for ( …
Metabolic engineering of Corynebacterium glutamicum for efficient production of optically pure (2R,3R)-2,3-butanediol.
Kou M, Cui Z, Fu J, Dai W, Wang Z, Chen T. Kou M, et al. Microb Cell Fact. 2022 Jul 25;21(1):150. doi: 10.1186/s12934-022-01875-5. Microb Cell Fact. 2022. PMID: 35879766 Free PMC article.
However, some (2R,3R)-2,3-butanediol overproducing strains are pathogenic such as Enterobacter cloacae and Klebsiella oxytoca. ...The optical purity of the resulting (2R,3R)-2,3-butanediol surpassed 98%. CONCLU …
However, some (2R,3R)-2,3-butanediol overproducing strains are pathogenic such as Enterobacter cloacae an …
Engineered Serratia marcescens for efficient (3R)-acetoin and (2R,3R)-2,3-butanediol production.
Bai F, Dai L, Fan J, Truong N, Rao B, Zhang L, Shen Y. Bai F, et al. J Ind Microbiol Biotechnol. 2015 May;42(5):779-86. doi: 10.1007/s10295-015-1598-5. Epub 2015 Feb 10. J Ind Microbiol Biotechnol. 2015. PMID: 25663525 Free article.
Excess (2R,3R)-2,3-butanediol dehydrogenase could accelerate the reaction from (3R)-acetoin to (2R,3R)-2,3-butanediol and lead to (2R,3R)-2,3-butanediol accumulation. In fed-b …
Excess (2R,3R)-2,3-butanediol dehydrogenase could accelerate the reaction from (3R)-acetoin to (2R …
Identification and characterization of a mycobacterial (2R,3R)-2,3-butanediol dehydrogenase.
Takeda M, Muranushi T, Inagaki S, Nakao T, Motomatsu S, Suzuki I, Koizumi J. Takeda M, et al. Biosci Biotechnol Biochem. 2011;75(12):2384-9. doi: 10.1271/bbb.110607. Epub 2011 Dec 7. Biosci Biotechnol Biochem. 2011. PMID: 22146728 Free article.
Hydroxyacetone was produced from R-PD by an enzymatic reaction, indicating that position 2 of the substrate was oxidized. The enzyme activity was highest for (2R,3R)-2,3-butanediol (R,R-BD), enabling the enzyme to be identified as (2R …
Hydroxyacetone was produced from R-PD by an enzymatic reaction, indicating that position 2 of the substrate was oxidized. The enzyme activit …
85 results