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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1826 1
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1891 2
1908 1
1937 1
1943 2
1945 1
1946 1
1948 1
1949 1
1951 1
1952 2
1953 2
1954 3
1955 2
1956 3
1957 2
1958 1
1959 2
1961 2
1962 1
1964 3
1965 8
1966 2
1967 6
1968 4
1969 8
1970 9
1971 3
1972 1
1973 5
1974 2
1975 7
1976 3
1977 4
1978 7
1979 3
1980 7
1981 7
1982 10
1983 4
1984 5
1985 3
1986 6
1987 12
1988 1
1989 7
1990 5
1991 13
1992 7
1993 7
1994 12
1995 9
1996 7
1997 8
1998 14
1999 16
2000 12
2001 10
2002 12
2003 10
2004 7
2005 16
2006 17
2007 11
2008 14
2009 14
2010 15
2011 13
2012 18
2013 10
2014 15
2015 13
2016 17
2017 15
2018 24
2019 16
2020 17
2021 19
2022 16
2023 20
2024 6

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Quoted phrase not found in phrase index: "(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) (2S)-3-hydroxy-2-phenylpropanoate"
Page 1
Antiemetic Agents.
[No authors listed] [No authors listed] 2018 Jan 15. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2018 Jan 15. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31643401 Free Books & Documents. Review.
Nevertheless, some anticholinergics are used alone or in combination with other agents for mild nausea and vomiting, including scopolamine and hyoscyamine. Phenothiazines, which are typically used as antipsychotic medications, also have antiemetic effects and several minor …
Nevertheless, some anticholinergics are used alone or in combination with other agents for mild nausea and vomiting, including scopolamine a …
Hyoscyamine.
[No authors listed] [No authors listed] 2017 Jul 7. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2017 Jul 7. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31644177 Free Books & Documents. Review.
Hyoscyamine as a natural plant alkaloid derivative and anticholinergic that is used to treat mild to moderate nausea, motion sickness, hyperactive bladder and allergic rhinitis. Hyoscyamine has not been implicated in causing liver enzyme elevations or clinically app
Hyoscyamine as a natural plant alkaloid derivative and anticholinergic that is used to treat mild to moderate nausea, motion sickness
Nightshade Vegetables: A Dietary Trigger for Worsening Inflammatory Bowel Disease and Irritable Bowel Syndrome?
Kuang R, Levinthal DJ, Ghaffari AA, Del Aguila de Rivers CR, Tansel A, Binion DG. Kuang R, et al. Dig Dis Sci. 2023 Jul;68(7):2853-2860. doi: 10.1007/s10620-023-07955-9. Epub 2023 May 19. Dig Dis Sci. 2023. PMID: 37202602 Review.
Many pharmacologically active compounds used in traditional medicine, including atropine and hyoscyamine, are derived from Nightshades. In addition to these beneficial pharmacologic agents, Nightshade-derived glycoalkaloid compounds, a key defense mechanism against predati …
Many pharmacologically active compounds used in traditional medicine, including atropine and hyoscyamine, are derived from Nightshade …
Nocturnal enuresis.
Kiddoo D. Kiddoo D. BMJ Clin Evid. 2011 Jan 31;2011:0305. BMJ Clin Evid. 2011. PMID: 21477399 Free PMC article. Review.
CONCLUSIONS: In this systematic review we present information relating to the effectiveness and safety of the following interventions: acupuncture, anticholinergics (oxybutynin, tolterodine, hyoscyamine), desmopressin, dry bed training, enuresis alarm, hypnotherapy, standa …
CONCLUSIONS: In this systematic review we present information relating to the effectiveness and safety of the following interventions: acupu …
Nocturnal enuresis.
Kiddoo D. Kiddoo D. BMJ Clin Evid. 2007 Oct 1;2007:0305. BMJ Clin Evid. 2007. PMID: 19450363 Free PMC article. Review.
CONCLUSIONS: In this systematic review we present information relating to the effectiveness and safety of the following interventions: acupuncture, anticholinergics (oxybutynin, tolterodine, hyoscyamine), desmopression, dry bed training, enuresis alarm, hypnotherapy, stand …
CONCLUSIONS: In this systematic review we present information relating to the effectiveness and safety of the following interventions: acupu …
Tropane alkaloid biosynthesis: a centennial review.
Huang JP, Wang YJ, Tian T, Wang L, Yan Y, Huang SX. Huang JP, et al. Nat Prod Rep. 2021 Sep 23;38(9):1634-1658. doi: 10.1039/d0np00076k. Nat Prod Rep. 2021. PMID: 33533391 Review.
Covering: 1917 to 2020Tropane alkaloids (TAs) are a remarkable class of plant secondary metabolites, which are characterized by an 8-azabicyclo[3.2.1]octane (nortropane) ring. Members of this class, such as hyoscyamine, scopolamine, and cocaine, are well known for their lo …
Covering: 1917 to 2020Tropane alkaloids (TAs) are a remarkable class of plant secondary metabolites, which are characterized by an 8-azabicy …
Engineered Microbes for Producing Anticholinergics.
Courdavault V, Cassereau J, Papon N. Courdavault V, et al. Chembiochem. 2021 Apr 16;22(8):1368-1370. doi: 10.1002/cbic.202000757. Epub 2020 Dec 17. Chembiochem. 2021. PMID: 33215811 Review.
The tropane alkaloids (TAs) hyoscyamine and scopolamine function as acetylcholine receptor antagonists and are used clinically as parasympatholytics to treat neuromuscular disorders in humans. ...Based on the landmark microbial production of the antimalarial semi-synthetic …
The tropane alkaloids (TAs) hyoscyamine and scopolamine function as acetylcholine receptor antagonists and are used clinically as par …
Tropane Alkaloids: Chemistry, Pharmacology, Biosynthesis and Production.
Kohnen-Johannsen KL, Kayser O. Kohnen-Johannsen KL, et al. Molecules. 2019 Feb 22;24(4):796. doi: 10.3390/molecules24040796. Molecules. 2019. PMID: 30813289 Free PMC article. Review.
The TAs, which are characterized by their unique bicyclic tropane ring system, can be divided into three major groups: hyoscyamine and scopolamine, cocaine and calystegines. Although all TAs have the same basic structure, they differ immensely in their biological, chemical …
The TAs, which are characterized by their unique bicyclic tropane ring system, can be divided into three major groups: hyoscyamine an …
Elicitation of Hyoscyamine Production in Datura stramonium L. Plants Using Tobamoviruses.
Mihálik D, Hančinský R, Kaňuková Š, Mrkvová M, Kraic J. Mihálik D, et al. Plants (Basel). 2022 Dec 1;11(23):3319. doi: 10.3390/plants11233319. Plants (Basel). 2022. PMID: 36501358 Free PMC article.
Datura stramonium L. produces tropane alkaloids, and the hyoscyamine is dominant among them. Hyoscyamine is produced by hairy root cultures in vitro derived from native plants or plants with the genetically modified biosynthetic pathway for hyoscyamine. ...Th …
Datura stramonium L. produces tropane alkaloids, and the hyoscyamine is dominant among them. Hyoscyamine is produced by hairy …
MIL-53(Fe)-derived ant nest structured porous carbon nanospheres CuFeS(2) /C for the determination of atropine enantiomeric impurity L-hyoscyamine.
Zhu J, Li K. Zhu J, et al. Chirality. 2022 Dec;34(12):1526-1537. doi: 10.1002/chir.23500. Epub 2022 Oct 3. Chirality. 2022. PMID: 36190759
In this work, an ant nest structured porous carbon nanosphere had been developed for the recognition detection of the atropine (ATP) enantiomers D-hyoscyamine (D-HSM) and L-hyoscyamine (L-HSM). Firstly, Fe-based organic framework was used as the substrate, an …
In this work, an ant nest structured porous carbon nanosphere had been developed for the recognition detection of the atropine (ATP) enantio …
586 results