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642 results

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Quoted phrase not found in phrase index: "(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) (2S)-3-hydroxy-2-phenylpropanoate"
Page 1
Atropine.
[No authors listed] [No authors listed] 2024 Nov 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2024 Nov 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000531 Free Books & Documents. Review.
Hyoscyamine.
[No authors listed] [No authors listed] 2017 Jul 7. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2017 Jul 7. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31644177 Free Books & Documents. Review.
Hyoscyamine as a natural plant alkaloid derivative and anticholinergic that is used to treat mild to moderate nausea, motion sickness, hyperactive bladder and allergic rhinitis. Hyoscyamine has not been implicated in causing liver enzyme elevations or clinically app …
Hyoscyamine as a natural plant alkaloid derivative and anticholinergic that is used to treat mild to moderate nausea, motion sickness …
Drugs for Irritable Bowel Syndrome.
[No authors listed] [No authors listed] Med Lett Drugs Ther. 2020 Mar 23;62(1594):25-32. Med Lett Drugs Ther. 2020. PMID: 32324172 No abstract available.
Complexation of tropane alkaloids by cyclodextrins.
Asztemborska M, Ceborska M, Pietrzak M. Asztemborska M, et al. Carbohydr Polym. 2019 Apr 1;209:74-81. doi: 10.1016/j.carbpol.2019.01.011. Epub 2019 Jan 4. Carbohydr Polym. 2019. PMID: 30732827
Moreover, the analysis of the obtained crystal structure of beta-cyclodextrin/(-)-hyoscyamine complex reveals that two molecules of (-)-hyoscyamine oriented in head-to-tail mode are tightly fitted inside head-to-head beta-cyclodextrin dimer. Conformation of (-)-h …
Moreover, the analysis of the obtained crystal structure of beta-cyclodextrin/(-)-hyoscyamine complex reveals that two molecules of ( …
Drugs for irritable bowel syndrome.
[No authors listed] [No authors listed] Med Lett Drugs Ther. 2025 Feb 3;67(1721):17-24. doi: 10.58347/tml.2025.1721a. Med Lett Drugs Ther. 2025. PMID: 39912839 No abstract available.
Ultrasound-assisted extraction of scopolamine and hyoscyamine from Hyoscyamus niger roots using central compost design.
Ahmadpour R, Zanjani BM, Garoosi GA, Farjaminezhad R, Haddad R. Ahmadpour R, et al. Heliyon. 2024 Oct 5;10(19):e38856. doi: 10.1016/j.heliyon.2024.e38856. eCollection 2024 Oct 15. Heliyon. 2024. PMID: 39435070 Free PMC article.
Hyoscyamus niger is an important medicinal plant used in medicine and contains tropane alkaloid compounds such as hyoscyamine and scopolamine. In this study, after the selection of the solvent for extracting hyoscyamine and scopolamine, the central composite design …
Hyoscyamus niger is an important medicinal plant used in medicine and contains tropane alkaloid compounds such as hyoscyamine and sco …
Modeling the functionalized genistein-hyoscyamine derivatives.
Abd-ElSalam R, Khaled NA, Ibrahim MA. Abd-ElSalam R, et al. Sci Rep. 2025 May 13;15(1):16662. doi: 10.1038/s41598-025-00371-1. Sci Rep. 2025. PMID: 40360535 Free PMC article.
Thus, in this study we aimed to validate and functionalize modeled composite of Genistein-Hyoscyamine as to further employ the best match in food processing sector as a novel food-additive for functional-foods serving enuretic patients. ...
Thus, in this study we aimed to validate and functionalize modeled composite of Genistein-Hyoscyamine as to further employ the best m …
Regioselectivity of hyoscyamine 6beta-hydroxylase-catalysed hydroxylation as revealed by high-resolution structural information and QM/MM calculations.
Kluza A, Wojdyla Z, Mrugala B, Kurpiewska K, Porebski PJ, Niedzialkowska E, Minor W, Weiss MS, Borowski T. Kluza A, et al. Dalton Trans. 2020 Apr 7;49(14):4454-4469. doi: 10.1039/d0dt00302f. Dalton Trans. 2020. PMID: 32182320 Free PMC article.
Hyoscyamine 6beta-hydroxylase (H6H) is a bifunctional non-heme 2-oxoglutarate/Fe2+-dependent dioxygenase that catalyzes the two final steps in the biosynthesis of scopolamine. ...In particular, the role of two prominent residues was revealed - Glu-116 that interacts with t …
Hyoscyamine 6beta-hydroxylase (H6H) is a bifunctional non-heme 2-oxoglutarate/Fe2+-dependent dioxygenase that catalyzes the two final …
Effect of saccharides on secondary compounds production from stem derived callus of Datura inoxia.
Twaij BM, Taha AJ, Bhuiyan FH, Hasan MN. Twaij BM, et al. Biotechnol Rep (Amst). 2022 Jan 25;33:e00701. doi: 10.1016/j.btre.2022.e00701. eCollection 2022 Mar. Biotechnol Rep (Amst). 2022. PMID: 35145885 Free PMC article.
Datura inoxia is a subshrub plant known for its toxicity which results from the presence of the tropane alkaloid scopolamine and hyoscyamine. Saccharides are one of the most important elicitors that can alter physiological and biochemical responses in plants. ...The additi …
Datura inoxia is a subshrub plant known for its toxicity which results from the presence of the tropane alkaloid scopolamine and hyoscyam …
Engineered Microbes for Producing Anticholinergics.
Courdavault V, Cassereau J, Papon N. Courdavault V, et al. Chembiochem. 2021 Apr 16;22(8):1368-1370. doi: 10.1002/cbic.202000757. Epub 2020 Dec 17. Chembiochem. 2021. PMID: 33215811 Review.
The tropane alkaloids (TAs) hyoscyamine and scopolamine function as acetylcholine receptor antagonists and are used clinically as parasympatholytics to treat neuromuscular disorders in humans. ...Based on the landmark microbial production of the antimalarial semi-synthetic …
The tropane alkaloids (TAs) hyoscyamine and scopolamine function as acetylcholine receptor antagonists and are used clinically as par …
642 results