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Quoted phrases not found in phrase index: "(E)-3-phenylpropenenitrile", "3-phenyl-2-propenenitrile", "b-cyanostyrene"
Page 1
On the mechanism of Ni(ii)-promoted Michael-type hydroamination of acrylonitrile and its substituted derivatives.
Lapointe S, Zargarian D. Lapointe S, et al. Dalton Trans. 2016 Oct 12;45(40):15800-15810. doi: 10.1039/c6dt02105k. Dalton Trans. 2016. PMID: 27410777
The catalytic activities for the addition of primary amines to crotonitrile, methacrylonitrile, and cinnamonitrile were found to depend on the precursor and the amine used, as well as on the reaction time. ...We have also prepared and characterized the cationic acrylonitri …
The catalytic activities for the addition of primary amines to crotonitrile, methacrylonitrile, and cinnamonitrile were found to depe …
Characterization of the Nit6803 nitrilase homolog from the cyanotroph Pseudomonas fluorescens NCIMB 11764.
Jones LB, Wang X, Gullapalli JS, Kunz DA. Jones LB, et al. Biochem Biophys Rep. 2021 Jan 16;25:100893. doi: 10.1016/j.bbrep.2020.100893. eCollection 2021 Mar. Biochem Biophys Rep. 2021. PMID: 33506113 Free PMC article.
The two enzymes exhibit a similar substrate profile, however, for Nit11764, cinnamonitrile, was found to be an even better substrate than fumaronitrile the best substrate previously identified for Nit6803. A higher affinity for cinnamonitrile (Km 1.27 mM) compared t …
The two enzymes exhibit a similar substrate profile, however, for Nit11764, cinnamonitrile, was found to be an even better substrate …
Cinnamonitrile Adjuvants Restore Susceptibility to beta-Lactams against Methicillin-Resistant Staphylococcus aureus.
Speri E, Kim C, De Benedetti S, Qian Y, Lastochkin E, Fishovitz J, Fisher JF, Mobashery S. Speri E, et al. ACS Med Chem Lett. 2019 Jul 1;10(8):1148-1153. doi: 10.1021/acsmedchemlett.9b00169. eCollection 2019 Aug 8. ACS Med Chem Lett. 2019. PMID: 31413798 Free PMC article.
However, the emergence of methicillin-resistant S. aureus (MRSA) renders them clinically precarious. We describe a class of cinnamonitrile adjuvants that restore the activity of oxacillin (a penicillin member of the beta-lactams) against MRSA. ...
However, the emergence of methicillin-resistant S. aureus (MRSA) renders them clinically precarious. We describe a class of cinnamonitril …
Distribution of enzymes that catalyse reactions of glutathione with alpha beta-unsaturated compounds.
Chasseaud LF. Chasseaud LF. Biochem J. 1973 Apr;131(4):765-9. doi: 10.1042/bj1310765. Biochem J. 1973. PMID: 4722451 Free PMC article.
A study of the distribution of glutathione S-alkenetransferases in the livers of vertebrate species suggests that different enzymes may catalyse reactions of GSH with (i) trans-benzylideneacetone, (ii) 2,3-dimethyl-4(2-methylenebutyryl)phenoxyacetic acid, (iii) cinnamonitrile …
A study of the distribution of glutathione S-alkenetransferases in the livers of vertebrate species suggests that different enzymes may cata …
Activity-dependent fluorescent labeling of bacteria that degrade toluene via toluene 2,3-dioxygenase.
Keener WK, Watwood ME, Apel WA. Keener WK, et al. Appl Microbiol Biotechnol. 1998 Apr;49(4):455-62. doi: 10.1007/s002530051198. Appl Microbiol Biotechnol. 1998. PMID: 9615486
Alternative substrates for the toluene 2,3-dioxygenase pathway of several pseudomonads served as enzyme-activity-dependent fluorescent probes for the bacteria. Phenylacetylene and cinnamonitrile were transformed to fluorescent and brightly colored products by Pseudomonas p …
Alternative substrates for the toluene 2,3-dioxygenase pathway of several pseudomonads served as enzyme-activity-dependent fluorescent probe …
Influence of the electronic characteristics of N-donor ligands in the excited state of heteronuclear gold(I)-copper(I) systems.
López-de-Luzuriaga JM, Monge M, Olmos ME, Pascual D, Rodríguez-Castillo M. López-de-Luzuriaga JM, et al. Inorg Chem. 2011 Aug 1;50(15):6910-21. doi: 10.1021/ic102550z. Epub 2011 Jun 30. Inorg Chem. 2011. PMID: 21718064
By reaction of the heterometallic gold-silver complexes [{AuAg(C(6)F(5))(2)(NC-Me)}(2)](n) or [{AuAg(C(6)Cl(5))(2)(NC-Me)}(2)](n) and CuCl in the presence of pyrimidine and different nitrile ligands (acetonitrile, benzonitrile, and cinnamonitrile), the heteronuclear comple …
By reaction of the heterometallic gold-silver complexes [{AuAg(C(6)F(5))(2)(NC-Me)}(2)](n) or [{AuAg(C(6)Cl(5))(2)(NC-Me)}(2)](n) and CuCl i …
Nitriles in heterocyclic synthesis. Part III: New sulpha drugs related to cyanopyridine derivatives.
Abdel Hafez AA, Awad IM, Abdel Monem MI. Abdel Hafez AA, et al. J Chem Technol Biotechnol. 1992;55(4):333-8. doi: 10.1002/jctb.280550405. J Chem Technol Biotechnol. 1992. PMID: 1369050
4-Hydroxyacetophenone (1) was reacted with cinnamonitrile derivatives (2-6) to give 3-cyano-4-(substituted phenyl)-6-(p-hydroxyphenyl)-pyridines (7-11). ...
4-Hydroxyacetophenone (1) was reacted with cinnamonitrile derivatives (2-6) to give 3-cyano-4-(substituted phenyl)-6-(p-hydroxyphenyl …
Regulation of lipopolysaccharide-induced inducible nitric-oxide synthase expression through the nuclear factor-kappaB pathway and interferon-beta/tyrosine kinase 2/Janus tyrosine kinase 2-signal transducer and activator of transcription-1 signaling cascades by 2-naphthylethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (THI 53), a new synthetic isoquinoline alkaloid.
Kim HJ, Tsoyi K, Heo JM, Kang YJ, Park MK, Lee YS, Lee JH, Seo HG, Yun-Choi HS, Chang KC. Kim HJ, et al. J Pharmacol Exp Ther. 2007 Feb;320(2):782-9. doi: 10.1124/jpet.106.112052. Epub 2006 Nov 15. J Pharmacol Exp Ther. 2007. PMID: 17108235
LPS-mediated iNOS protein induction was inhibited significantly by the specific tyrosine kinase inhibitor alpha-cyano-(3-hydroxy-4-nitro)cinnamonitrile (AG126) as well as by THI 53. In addition, a c-Jun NH(2)-terminal kinase (JNK) inhibitor anthra[1,9-cd]pyrazole-6 (2H)-on …
LPS-mediated iNOS protein induction was inhibited significantly by the specific tyrosine kinase inhibitor alpha-cyano-(3-hydroxy-4-nitro) …
A Catecholaldimine-Based NiII-Complex as an Effective Catalyst for the Direct Conversion of Alcohols to trans-Cinnamonitriles and Aldehydes.
Sharma V, Chavan KA, Mali G, Sarkar D, Lama P, Majumder M, Erande RD, Metre RK. Sharma V, et al. J Org Chem. 2023 Jun 2;88(11):7448-7453. doi: 10.1021/acs.joc.2c03067. Epub 2023 May 8. J Org Chem. 2023. PMID: 37155715
Complex 1 showed excellent catalytic activity where aromatic and heterocyclic alcohols were rapidly converted into trans-cinnamonitrile in a one-pot manner via oxidative olefination in the presence of KOH. The potential of the disclosed catalyst and the results obta …
Complex 1 showed excellent catalytic activity where aromatic and heterocyclic alcohols were rapidly converted into trans-cinnamoni …
Controlled microwave-assisted reactions: A facile synthesis of polyfunctionally substituted phthalazines as dual EGFR and PI3K inhibitors in CNS SNB-75 cell line.
Hassan Nazmy M, Ahmed Mekheimer R, Shoman ME, Abo-Elsebaa M, Abd-Elmonem M, Usef Sadek K. Hassan Nazmy M, et al. Bioorg Chem. 2022 May;122:105740. doi: 10.1016/j.bioorg.2022.105740. Epub 2022 Mar 12. Bioorg Chem. 2022. PMID: 35298961
An efficient one-pot synthesis of polyfunctionalized phthalazines derivatives was developed by reacting ethyl 1-aryl-5-cyano-1,6-dihydro-4-methyl-6-oxo-3-pyridazine-carboxylates with cinnamonitrile derivatives and the cycloaddition reaction of thieno[3,4-d]pyridazines with …
An efficient one-pot synthesis of polyfunctionalized phthalazines derivatives was developed by reacting ethyl 1-aryl-5-cyano-1,6-dihydro-4-m …
41 results