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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 2
1995 2
1997 2
1999 3
2002 1
2003 1
2004 5
2005 3
2006 3
2007 4
2008 3
2009 9
2010 4
2011 3
2012 7
2013 4
2014 7
2015 18
2016 11
2017 20
2018 16
2019 9
2020 11
2021 16
2022 14
2023 9
2024 12

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175 results

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Page 1
Epidemiology of Parkinson's disease.
Tysnes OB, Storstein A. Tysnes OB, et al. J Neural Transm (Vienna). 2017 Aug;124(8):901-905. doi: 10.1007/s00702-017-1686-y. Epub 2017 Feb 1. J Neural Transm (Vienna). 2017. PMID: 28150045 Review.
Non-motor symptoms in PD have gained increasing attention and both motor and non-motor signs are now included among the supportive criteria. The cause of PD is unknown in most cases. ...
Non-motor symptoms in PD have gained increasing attention and both motor and non-motor signs are now included among the …
Premotor parkinsonism models.
Bezard E, Fernagut PO. Bezard E, et al. Parkinsonism Relat Disord. 2014 Jan;20 Suppl 1:S17-9. doi: 10.1016/S1353-8020(13)70007-5. Parkinsonism Relat Disord. 2014. PMID: 24262174 Review.
Several studies in toxin- or gene-based models have specifically investigated these non-motor signs in a premotor context. Altered olfactory discrimination has been reproduced both in toxin- and in gene-based models, and genetic models may also reproduce the …
Several studies in toxin- or gene-based models have specifically investigated these non-motor signs in a premotor conte …
Parkinson's disease.
Béné R, Antić S, Budisić M, Lisak M, Trkanjec Z, Demarin V, Podobnik-Sarkanji S. Béné R, et al. Acta Clin Croat. 2009 Sep;48(3):377-80. Acta Clin Croat. 2009. PMID: 20055267 Review.
The most characteristic motor symptoms for Parkinson's disease include bradykinesia, rigidity, resting tremor and postural instability, while many patients also have non-motor signs and symptoms. The key therapeutic agent in the treatment of Parkinson's disea …
The most characteristic motor symptoms for Parkinson's disease include bradykinesia, rigidity, resting tremor and postural instability, whil …
Synaptojanin1 deficiency upregulates basal autophagosome formation in astrocytes.
Pan PY, Zhu J, Rizvi A, Zhu X, Tanaka H, Dreyfus CF. Pan PY, et al. J Biol Chem. 2021 Jul;297(1):100873. doi: 10.1016/j.jbc.2021.100873. Epub 2021 Jun 11. J Biol Chem. 2021. PMID: 34126070 Free PMC article.
While autophagy pathways are heavily researched in heterologous cells and neurons, regulation of autophagy in the astrocyte, the most abundant cell type in the mammalian brain, is less well understood. Missense mutations in the Synj1 gene encoding Synaptojanin1 (Syn …
While autophagy pathways are heavily researched in heterologous cells and neurons, regulation of autophagy in the astrocyte, the most abunda …
Lateralisation in Parkinson disease.
Riederer P, Jellinger KA, Kolber P, Hipp G, Sian-Hülsmann J, Krüger R. Riederer P, et al. Cell Tissue Res. 2018 Jul;373(1):297-312. doi: 10.1007/s00441-018-2832-z. Epub 2018 Apr 14. Cell Tissue Res. 2018. PMID: 29656343 Review.
As a consequence, not only the obvious lateralisation of motor symptoms occurs but also patterns of associated non-motor signs are defined, which include cognitive functions, sleep behaviour or olfaction. ...
As a consequence, not only the obvious lateralisation of motor symptoms occurs but also patterns of associated non-motor si …
Mini-review: Synaptojanin 1 and its implications in membrane trafficking.
Choudhry H, Aggarwal M, Pan PY. Choudhry H, et al. Neurosci Lett. 2021 Nov 20;765:136288. doi: 10.1016/j.neulet.2021.136288. Epub 2021 Oct 9. Neurosci Lett. 2021. PMID: 34637856 Free PMC article. Review.
This mini-review aims to summarize a growing body of literature on synaptojanin 1 (Synj1), a phosphoinositide phosphatase that was initially known to have a prominent role in synaptic vesicle recycling. Synj1 is coded by the SYNJ1 gene, whose mutations and variants …
This mini-review aims to summarize a growing body of literature on synaptojanin 1 (Synj1), a phosphoinositide phosphatase that was initially …
Is there a paraneoplastic ALS?
Corcia P, Gordon PH, Camdessanche JP. Corcia P, et al. Amyotroph Lateral Scler Frontotemporal Degener. 2015 Jun;16(3-4):252-7. doi: 10.3109/21678421.2014.965178. Epub 2014 Oct 6. Amyotroph Lateral Scler Frontotemporal Degener. 2015. PMID: 25285651 Review.
Clinical features that warrant evaluation of neoplasm include upper motor neuron disease in elderly females, rapid progression, non-motor signs, and young onset. In conclusion, most examples of ALS and neoplasm do not constitute a classically established PNS. …
Clinical features that warrant evaluation of neoplasm include upper motor neuron disease in elderly females, rapid progression, non- …
Modeling Parkinson's disease in LRRK2 rodents.
Domenicale C, Magnabosco S, Morari M. Domenicale C, et al. Neuronal Signal. 2023 Aug 16;7(3):NS20220040. doi: 10.1042/NS20220040. eCollection 2023 Sep. Neuronal Signal. 2023. PMID: 37601008 Free PMC article. Review.
Disappointingly, however, LRRK2 rodents did not consistently phenocopy hypokinesia and nigro-striatal degeneration, or showed Lewy body-like aggregates. Instead, LRRK2 rodents manifested non-motor signs and dysregulated transmission at dopaminergic and non-do …
Disappointingly, however, LRRK2 rodents did not consistently phenocopy hypokinesia and nigro-striatal degeneration, or showed Lewy body-like …
175 results