Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 2
1949 1
1951 1
1953 1
1956 1
1958 1
1959 1
1961 1
1964 2
1965 14
1966 42
1967 57
1968 96
1969 79
1970 103
1971 80
1972 91
1973 108
1974 134
1975 83
1976 87
1977 106
1978 90
1979 95
1980 100
1981 95
1982 122
1983 96
1984 123
1985 125
1986 142
1987 155
1988 158
1989 214
1990 251
1991 292
1992 260
1993 346
1994 304
1995 279
1996 284
1997 244
1998 218
1999 202
2000 209
2001 193
2002 207
2003 199
2004 208
2005 226
2006 245
2007 224
2008 265
2009 273
2010 290
2011 303
2012 313
2013 319
2014 363
2015 332
2016 338
2017 346
2018 360
2019 356
2020 374
2021 337
2022 363
2023 260
2024 149

Text availability

Article attribute

Article type

Publication date

Search Results

11,561 results

Results by year

Filters applied: . Clear all
Quoted phrase not found in phrase index: "1,2-dihydropyrazolo[4,3-e]pyrimidin-4-one"
Page 1
Febuxostat compared with allopurinol in patients with hyperuricemia and gout.
Becker MA, Schumacher HR Jr, Wortmann RL, MacDonald PA, Eustace D, Palo WA, Streit J, Joseph-Ridge N. Becker MA, et al. N Engl J Med. 2005 Dec 8;353(23):2450-61. doi: 10.1056/NEJMoa050373. N Engl J Med. 2005. PMID: 16339094 Free article. Clinical Trial.
Although the incidence of gout flares diminished with continued treatment, the overall incidence during weeks 9 through 52 was similar in all groups: 64 percent of patients receiving 80 mg of febuxostat, 70 percent of those receiving 120 mg of febuxostat, and 64 percent of those …
Although the incidence of gout flares diminished with continued treatment, the overall incidence during weeks 9 through 52 was similar in al …
Allopurinol kinetics.
Hande K, Reed E, Chabner B. Hande K, et al. Clin Pharmacol Ther. 1978 May;23(5):598-605. doi: 10.1002/cpt1978235598. Clin Pharmacol Ther. 1978. PMID: 639435
With this assay, serum disappearance characteristics of intravenous and orally administered allopurinol have been investigated in man. Serum concentrations of both allopurinol and oxipurinol reach levels above 1 X 10(-5) M within minutes of intravenous administratio …
With this assay, serum disappearance characteristics of intravenous and orally administered allopurinol have been investigated in man …
Allopurinol hypersensitivity: Pathogenesis and prevention.
Stamp LK, Chapman PT. Stamp LK, et al. Best Pract Res Clin Rheumatol. 2020 Aug;34(4):101501. doi: 10.1016/j.berh.2020.101501. Epub 2020 Apr 4. Best Pract Res Clin Rheumatol. 2020. PMID: 32265121 Review.
Allopurinol, a first line urate-lowering therapy, has been associated with serious cutaneous reactions that have a high mortality. A number of risk factors for these serious adverse reactions have been identified including ethnicity, HLA-B5801 genotype, kidney impairment,
Allopurinol, a first line urate-lowering therapy, has been associated with serious cutaneous reactions that have a high mortality. A
Allopurinol.
[No authors listed] [No authors listed] Br Med J. 1967 Feb 25;1(5538):483. Br Med J. 1967. PMID: 6017531 Free PMC article. No abstract available.
How to prevent allopurinol hypersensitivity reactions?
Stamp LK, Barclay ML. Stamp LK, et al. Rheumatology (Oxford). 2018 Jan 1;57(suppl_1):i35-i41. doi: 10.1093/rheumatology/kex422. Rheumatology (Oxford). 2018. PMID: 29272508 Review.
Allopurinol hypersensitivity syndrome (AHS) is a severe and sometimes life-threatening adverse drug reaction. ...A low starting allopurinol dose may reduce AHS risk, but the relationship between maintenance dose and AHS is more controversial. ...
Allopurinol hypersensitivity syndrome (AHS) is a severe and sometimes life-threatening adverse drug reaction. ...A low starting al
Allopurinol in dermatology.
Tsai TF, Yeh TY. Tsai TF, et al. Am J Clin Dermatol. 2010;11(4):225-32. doi: 10.2165/11533190-000000000-00000. Am J Clin Dermatol. 2010. PMID: 20509717 Review.
In dermatology, allopurinol is best known for its severe cutaneous adverse reactions. ...Allopurinol may express its therapeutic effects via its antioxidation or anti-inflammatory properties, or its ability to improve vascular function....
In dermatology, allopurinol is best known for its severe cutaneous adverse reactions. ...Allopurinol may express its therapeut …
Allopurinol-induced DRESS syndrome.
Markel A. Markel A. Isr Med Assoc J. 2005 Oct;7(10):656-60. Isr Med Assoc J. 2005. PMID: 16259349 Free article. Review.
Complications, including renal calculi, uric acid nephropathy and gout, occur in a small proportion of patients. Allopurinol, an analog of hypoxanthine, has been widely used in clinical practice for over 30 years for the treatment of hyperuricemia and gout. ...A syndrome c …
Complications, including renal calculi, uric acid nephropathy and gout, occur in a small proportion of patients. Allopurinol, an anal …
Incidence of allopurinol-induced severe cutaneous adverse drug reaction in Malaysia.
Ng WL, Lim KS, Hariraj V, Lee SC, Wo WK, Ramli A, Lai PSM, Fong SL, Lim JR. Ng WL, et al. Br J Clin Pharmacol. 2022 Aug;88(8):3782-3788. doi: 10.1111/bcp.15327. Epub 2022 Apr 4. Br J Clin Pharmacol. 2022. PMID: 35318720 Free article.
AIMS: Allopurinol is known to cause severe cutaneous adverse drug reactions (SCAR) in Malaysia. However, the incidence of allopurinol-induced SCAR is unknown. Therefore, we aimed to determine the incidence of allopurinol-induced SCAR in Malaysia over 5 years …
AIMS: Allopurinol is known to cause severe cutaneous adverse drug reactions (SCAR) in Malaysia. However, the incidence of allopuri
Allopurinol induced erythroderma.
Sharma G, Govil DC. Sharma G, et al. Indian J Pharmacol. 2013 Nov-Dec;45(6):627-8. doi: 10.4103/0253-7613.121381. Indian J Pharmacol. 2013. PMID: 24347776 Free PMC article.
Allopurinol, a widely prescribed urate lowering agent is responsible for various adverse drug reactions, including erythroderma. ...Skin biopsy was consistent with drug induced erythroderma. Allopurinol was stopped and steroids were started. Patient improved over a
Allopurinol, a widely prescribed urate lowering agent is responsible for various adverse drug reactions, including erythroderma. ...S
11,561 results
You have reached the last available page of results. Please see the User Guide for more information.