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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1955 1
1964 1
1965 1
1966 1
1969 1
1972 1
1975 3
1976 1
1977 2
1978 1
1979 2
1980 1
1981 3
1982 2
1984 3
1985 5
1986 3
1987 7
1988 5
1989 6
1990 5
1991 7
1992 10
1993 21
1994 15
1995 23
1996 11
1997 30
1998 20
1999 18
2000 18
2001 25
2002 19
2003 26
2004 14
2005 27
2006 19
2007 34
2008 23
2009 27
2010 28
2011 28
2012 37
2013 44
2014 29
2015 49
2016 48
2017 46
2018 44
2019 74
2020 71
2021 86
2022 101
2023 102
2024 43

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1,138 results

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Page 1
Attenuating CD3 affinity in a PSMAxCD3 bispecific antibody enables killing of prostate tumor cells with reduced cytokine release.
Dang K, Castello G, Clarke SC, Li Y, Balasubramani A, Boudreau A, Davison L, Harris KE, Pham D, Sankaran P, Ugamraj HS, Deng R, Kwek S, Starzinski A, Iyer S, van Schooten W, Schellenberger U, Sun W, Trinklein ND, Buelow R, Buelow B, Fong L, Dalvi P. Dang K, et al. J Immunother Cancer. 2021 Jun;9(6):e002488. doi: 10.1136/jitc-2021-002488. J Immunother Cancer. 2021. PMID: 34088740 Free PMC article.
Cytokines were measured in culture supernatants to assess the ability of TNB-585 to induce tumor killing with low cytokine release. TNB-585-mediated T cell activation, proliferation, and cytotoxic granule formation were measured to investigate the mechanism of actio …
Cytokines were measured in culture supernatants to assess the ability of TNB-585 to induce tumor killing with low cytokine release. …
Persistence of 2,4,6-triamino-1,3,5-trinitrobenzene in the environment.
Christian O, Spencer M, Ladyman M, Persico F, Gutierrez-Carazo E, Kadansky E, Temple T. Christian O, et al. Environ Res. 2023 Dec 15;239(Pt 1):117378. doi: 10.1016/j.envres.2023.117378. Epub 2023 Oct 11. Environ Res. 2023. PMID: 37832768 Free article.
2,4,6-triamino-1,3,5-trinitrobenzene (TATB) is an Insensitive High Explosive (IHE) that is increasingly being used as a safer alternative to traditional energetic materials. ...
2,4,6-triamino-1,3,5-trinitrobenzene (TATB) is an Insensitive High Explosive (IHE) that is increasingly being us …
Neurotoxicity of 1,3,5-trinitrobenzene (TNB): immunohistochemical study of cerebrovascular permeability.
Chandra AM, Campbell GA, Reddy G, Qualls CW Jr. Chandra AM, et al. Vet Pathol. 1999 May;36(3):212-20. doi: 10.1354/vp.36-3-212. Vet Pathol. 1999. PMID: 10332829
1,3,5-Trinitrobenzene (TNB) is a soil and water contaminant at certain military installations. ...The presence of vacuolation and associated extravasated serum proteins in TNB-treated rats is an indication of vasogenic brain edema, which
1,3,5-Trinitrobenzene (TNB) is a soil and water contaminant at certain military installations. ...The pre
Hematological effects of 1,3,5-trinitrobenzene (TNB) in rats in vivo and in vitro.
Chandra AM, Qualls CW Jr, Reddy G, Meinkoth JH. Chandra AM, et al. J Toxicol Environ Health. 1995 Sep;46(1):57-72. doi: 10.1080/15287399509532018. J Toxicol Environ Health. 1995. PMID: 7666494
We studied the hematological effects of single and repeated exposure to 1,3,5-trinitrobenzene (TNB) in rats. Male F-344 rats were gavaged with TNB at 35.5 and 71 mg/kg in corn oil. ...A highly significant dose-dependent anemia with reduce …
We studied the hematological effects of single and repeated exposure to 1,3,5-trinitrobenzene (TNB) in ra …
1,3,5-Trinitrobenzene-induced alpha-2u-globulin nephropathy.
Kim S, Qualls CW Jr, Reddy G, Stair EL. Kim S, et al. Toxicol Pathol. 1997 Mar-Apr;25(2):195-201. doi: 10.1177/019262339702500209. Toxicol Pathol. 1997. PMID: 9125778
Male and female Fischer-344 (F-344) and male NCI-Black-Reiter (NBR) rats were dosed with 0, 35.5, or 71 mg 1,3,5-trinitrobenzene (TNB)/kg/day for 10 days. Male F-344 rats were dosed with TNB (0 and 35.5 mg/kg) for 20 and 30 days. ...Renal …
Male and female Fischer-344 (F-344) and male NCI-Black-Reiter (NBR) rats were dosed with 0, 35.5, or 71 mg 1,3,5-tri
Testicular effects of 1,3,5-trinitrobenzene (TNB). I. Dose response and reversibility studies.
Chandra AM, Qualls CW Jr, Reddy G. Chandra AM, et al. J Toxicol Environ Health. 1997 Mar;50(4):365-78. doi: 10.1080/009841097160401. J Toxicol Environ Health. 1997. PMID: 9120873
Testicular effects of TNB were characterized after single and multiple oral doses of TNB at 0, 35.5, and 71 mg/kg. Male Fischer 344 (F344) rats were killed after a single dose or after 4 and 10 daily doses of TNB. Testicular effects were not evident at the li …
Testicular effects of TNB were characterized after single and multiple oral doses of TNB at 0, 35.5, and 71 mg/kg. Male Fische …
TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity.
Ugamraj HS, Dang K, Ouisse LH, Buelow B, Chini EN, Castello G, Allison J, Clarke SC, Davison LM, Buelow R, Deng R, Iyer S, Schellenberger U, Manika SN, Bijpuria S, Musnier A, Poupon A, Cuturi MC, van Schooten W, Dalvi P. Ugamraj HS, et al. MAbs. 2022 Jan-Dec;14(1):2095949. doi: 10.1080/19420862.2022.2095949. MAbs. 2022. PMID: 35867844 Free PMC article.
By simultaneously binding two distinct epitopes on CD38, TNB-738 potently inhibited its enzymatic activity, which in turn boosted intracellular NAD+ levels and SIRT activities. Due to its silenced IgG4 Fc, TNB-738 did not deplete CD38-expressing cells, in contrast t …
By simultaneously binding two distinct epitopes on CD38, TNB-738 potently inhibited its enzymatic activity, which in turn boosted int …
Testicular effects of 1,3,5-trinitrobenzene (TNB). II. Immunolocalization of germ cells using proliferating cell nuclear antigen (PCNA) as an endogenous marker.
Chandra AM, Qualls CW Jr, Campbell GA, Reddy G. Chandra AM, et al. J Toxicol Environ Health. 1997 Mar;50(4):379-87. J Toxicol Environ Health. 1997. PMID: 9120874
The applicability of PCNA as a tool for the analysis of germ cells in rats treated with 1,3,5-trinitrobenzene (TNB), a potent testicular toxicant, was evaluated. ...Conventional (hematoxylin and eosin) staining of testes from rats treated with …
The applicability of PCNA as a tool for the analysis of germ cells in rats treated with 1,3,5-trinitrobenzene ( …
Pressure, directional dependent mechanical anisotropies and phase transition studies ofbeta-5-nitro-2,4-dihydro-3H-1,2,4-triazol-3-one (NTO) and 2,4,6-triamino-1,3,5-trinitrobenzene (TATB).
Rao EN, Rao VK. Rao EN, et al. J Phys Condens Matter. 2022 Dec 14;35(6). doi: 10.1088/1361-648X/aca199. J Phys Condens Matter. 2022. PMID: 36351301
This work highlights the effect of pressure ranging from 0 to 9 GPa on structural, directional dependent mechanical properties and unravel the previously unknown phase transitions of two important high energy molecular solids namely monoclinic-beta-Nitrotriazole (NTO) and 2,4,6-t …
This work highlights the effect of pressure ranging from 0 to 9 GPa on structural, directional dependent mechanical properties and unravel t …
Ex vivo efficacy of BCMA-bispecific antibody TNB-383B in relapsed/refractory multiple myeloma.
Foureau DM, Bhutani M, Robinson M, Guo F, Pham D, Buelow B, Steuerwald N, Rigby K, Tjaden E, Leonidas M, Paul BA, Atrash S, Ndiaye A, Symanowski JT, Voorhees PM, Usmani SZ. Foureau DM, et al. EJHaem. 2020 Aug 1;1(1):113-121. doi: 10.1002/jha2.69. eCollection 2020 Jul. EJHaem. 2020. PMID: 35847733 Free PMC article.
TNB-383B is a fully human BCMA-targeting T-cell engaging bispecific monoclonal antibody (T-BsAb). ...Cytokine response to TNB-383B was quantified by multiplex protein assay. Dose-dependent PC lysis was triggered in all cases by TNB-383B at doses as low as 0.0
TNB-383B is a fully human BCMA-targeting T-cell engaging bispecific monoclonal antibody (T-BsAb). ...Cytokine response to TNB-
1,138 results