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1,278 results

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Page 1
Persistence of 2,4,6-triamino-1,3,5-trinitrobenzene in the environment.
Christian O, Spencer M, Ladyman M, Persico F, Gutierrez-Carazo E, Kadansky E, Temple T. Christian O, et al. Environ Res. 2023 Dec 15;239(Pt 1):117378. doi: 10.1016/j.envres.2023.117378. Epub 2023 Oct 11. Environ Res. 2023. PMID: 37832768 Free article.
2,4,6-triamino-1,3,5-trinitrobenzene (TATB) is an Insensitive High Explosive (IHE) that is increasingly being used as a safer alternative to traditional energetic materials. ...
2,4,6-triamino-1,3,5-trinitrobenzene (TATB) is an Insensitive High Explosive (IHE) that is increasingly being us …
1,3,5-Trinitrobenzene-induced alpha-2u-globulin nephropathy.
Kim S, Qualls CW Jr, Reddy G, Stair EL. Kim S, et al. Toxicol Pathol. 1997 Mar-Apr;25(2):195-201. doi: 10.1177/019262339702500209. Toxicol Pathol. 1997. PMID: 9125778
Male and female Fischer-344 (F-344) and male NCI-Black-Reiter (NBR) rats were dosed with 0, 35.5, or 71 mg 1,3,5-trinitrobenzene (TNB)/kg/day for 10 days. Male F-344 rats were dosed with TNB (0 and 35.5 mg/kg) for 20 and 30 days. ...Renal …
Male and female Fischer-344 (F-344) and male NCI-Black-Reiter (NBR) rats were dosed with 0, 35.5, or 71 mg 1,3,5-tri …
Attenuating CD3 affinity in a PSMAxCD3 bispecific antibody enables killing of prostate tumor cells with reduced cytokine release.
Dang K, Castello G, Clarke SC, Li Y, Balasubramani A, Boudreau A, Davison L, Harris KE, Pham D, Sankaran P, Ugamraj HS, Deng R, Kwek S, Starzinski A, Iyer S, van Schooten W, Schellenberger U, Sun W, Trinklein ND, Buelow R, Buelow B, Fong L, Dalvi P. Dang K, et al. J Immunother Cancer. 2021 Jun;9(6):e002488. doi: 10.1136/jitc-2021-002488. J Immunother Cancer. 2021. PMID: 34088740 Free PMC article.
METHODS: Using genetically engineered transgenic rats (UniRat and OmniFlic) that express fully human IgG antibodies together with an NGS-based antibody discovery pipeline, we developed TNB-585, an anti-CD3xPSMA TCE for the treatment of mCRPC. TNB-585 pairs a tumor-t …
METHODS: Using genetically engineered transgenic rats (UniRat and OmniFlic) that express fully human IgG antibodies together with an NGS-bas …
Neurotoxicity of 1,3,5-trinitrobenzene (TNB): immunohistochemical study of cerebrovascular permeability.
Chandra AM, Campbell GA, Reddy G, Qualls CW Jr. Chandra AM, et al. Vet Pathol. 1999 May;36(3):212-20. doi: 10.1354/vp.36-3-212. Vet Pathol. 1999. PMID: 10332829
1,3,5-Trinitrobenzene (TNB) is a soil and water contaminant at certain military installations. ...In rats allowed to recover for 30 days, immunoreactivity to albumin was not seen. This study demonstrates that TNB-mediated tissue damage is …
1,3,5-Trinitrobenzene (TNB) is a soil and water contaminant at certain military installations. ...In rats …
Hematological effects of 1,3,5-trinitrobenzene (TNB) in rats in vivo and in vitro.
Chandra AM, Qualls CW Jr, Reddy G, Meinkoth JH. Chandra AM, et al. J Toxicol Environ Health. 1995 Sep;46(1):57-72. doi: 10.1080/15287399509532018. J Toxicol Environ Health. 1995. PMID: 7666494
We studied the hematological effects of single and repeated exposure to 1,3,5-trinitrobenzene (TNB) in rats. Male F-344 rats were gavaged with TNB at 35.5 and 71 mg/kg in corn oil. ...A highly significant dose-dependent anemia with reduce …
We studied the hematological effects of single and repeated exposure to 1,3,5-trinitrobenzene (TNB) in ra …
Testicular effects of 1,3,5-trinitrobenzene (TNB). I. Dose response and reversibility studies.
Chandra AM, Qualls CW Jr, Reddy G. Chandra AM, et al. J Toxicol Environ Health. 1997 Mar;50(4):365-78. doi: 10.1080/009841097160401. J Toxicol Environ Health. 1997. PMID: 9120873
Testicular effects of TNB were characterized after single and multiple oral doses of TNB at 0, 35.5, and 71 mg/kg. Male Fischer 344 (F344) rats were killed after a single dose or after 4 and 10 daily doses of TNB. Testicular effects were not evident at the li …
Testicular effects of TNB were characterized after single and multiple oral doses of TNB at 0, 35.5, and 71 mg/kg. Male Fische …
Pressure, directional dependent mechanical anisotropies and phase transition studies ofbeta-5-nitro-2,4-dihydro-3H-1,2,4-triazol-3-one (NTO) and 2,4,6-triamino-1,3,5-trinitrobenzene (TATB).
Rao EN, Rao VK. Rao EN, et al. J Phys Condens Matter. 2022 Dec 14;35(6). doi: 10.1088/1361-648X/aca199. J Phys Condens Matter. 2022. PMID: 36351301
This work highlights the effect of pressure ranging from 0 to 9 GPa on structural, directional dependent mechanical properties and unravel the previously unknown phase transitions of two important high energy molecular solids namely monoclinic-beta-Nitrotriazole (NTO) and 2,4,6-t …
This work highlights the effect of pressure ranging from 0 to 9 GPa on structural, directional dependent mechanical properties and unravel t …
cis- and trans-2-(4-tert-Butylcyclohexyloxy)-1,3,5-trinitrobenzene.
Spiniello M, White JM. Spiniello M, et al. Acta Crystallogr C. 2002 Feb;58(Pt 2):o94-6. doi: 10.1107/s0108270101019400. Epub 2002 Jan 23. Acta Crystallogr C. 2002. PMID: 11828120
The structures of cis- and trans-2-(4-tert-butylcyclohexyloxy)-1,3,5-trinitrobenzene, C(16)H(21)N(3)O(7), (I) and (II), respectively, were determined at low temperature in order to obtain accurate structural parameters for comparison purposes. ...
The structures of cis- and trans-2-(4-tert-butylcyclohexyloxy)-1,3,5-trinitrobenzene, C(16)H(21)N(3)O(7), (I) an …
1,3,5-Trinitrobenzene-induced encephalopathy in male Fischer-344 rats.
Chandra AM, Qualls CW Jr, Reddy G. Chandra AM, et al. Toxicol Pathol. 1995 Jul-Aug;23(4):527-32. doi: 10.1177/019262339502300410. Toxicol Pathol. 1995. PMID: 7501965
Administration of 1,3,5-trinitrobenzene (TNB) to male Fischer-344 rats produced ataxia after 6 or 7 oral doses (71 mg/kg). ...Rats administered daily oral doses of 35.5 mg/kg of TNB for 10 days and 35.5 and 71 mg/kg of TNB for 1 or …
Administration of 1,3,5-trinitrobenzene (TNB) to male Fischer-344 rats produced ataxia after 6 or 7 oral …
Testicular effects of 1,3,5-trinitrobenzene (TNB). II. Immunolocalization of germ cells using proliferating cell nuclear antigen (PCNA) as an endogenous marker.
Chandra AM, Qualls CW Jr, Campbell GA, Reddy G. Chandra AM, et al. J Toxicol Environ Health. 1997 Mar;50(4):379-87. J Toxicol Environ Health. 1997. PMID: 9120874
The applicability of PCNA as a tool for the analysis of germ cells in rats treated with 1,3,5-trinitrobenzene (TNB), a potent testicular toxicant, was evaluated. Male Fischer 344 (F344) rats were gavaged with TNB at 71 mg/kg or with corn …
The applicability of PCNA as a tool for the analysis of germ cells in rats treated with 1,3,5-trinitrobenzene ( …
1,278 results