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383 results

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Quoted phrase not found in phrase index: "1,7-dimethyl-3H-purine-2,6-dione"
Page 1
The associations of coffee consumption, coffee types, and caffeine metabolites with periodontitis: Results from NHANES 2009-2014.
Chen Q, Ge R, Wu Y, Wu Y, Yang H, Yu Y, Deng Q, Qiu Y, He B, Yan F, Li Y, Chen F. Chen Q, et al. J Periodontol. 2024 Aug;95(8):778-788. doi: 10.1002/JPER.23-0322. Epub 2023 Oct 10. J Periodontol. 2024. PMID: 37815812
Additionally, for urinary caffeine metabolites, there was a significant positive association between 1-methyluric acid (1-MU), 1,3-dimethyluric acid (1,3-DMU), 3,7-dimethyluric acid (3,7-DMU), 1,7-dimethylxanthine (1,7-DMX), or 5-actlyamino-6-amino-3-methylur …
Additionally, for urinary caffeine metabolites, there was a significant positive association between 1-methyluric acid (1-MU), 1,3-dimethylu …
Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior.
Cornelis MC, Kacprowski T, Menni C, Gustafsson S, Pivin E, Adamski J, Artati A, Eap CB, Ehret G, Friedrich N, Ganna A, Guessous I, Homuth G, Lind L, Magnusson PK, Mangino M, Pedersen NL, Pietzner M, Suhre K, Völzke H; Swiss Kidney Project on Genes in Hypertension (SKIPOGH) team; Bochud M, Spector TD, Grabe HJ, Ingelsson E. Cornelis MC, et al. Hum Mol Genet. 2016 Dec 15;25(24):5472-5482. doi: 10.1093/hmg/ddw334. Hum Mol Genet. 2016. PMID: 27702941 Free article.
Association between caffeine metabolites in urine and muscle strength in young and older adults: A cross-sectional study from NHANES 2011-2012.
Batista-da-Silva B, Limirio LS, de Oliveira EP. Batista-da-Silva B, et al. Clin Nutr. 2024 Jun;43(6):1584-1592. doi: 10.1016/j.clnu.2024.05.004. Epub 2024 May 7. Clin Nutr. 2024. PMID: 38759491
Caffeine and its metabolites in urine were quantified using ultra-high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry (1-methyluric acid, 3-methyluric acid, 7-methyluric acid, 1,3-dimethyluric acid, 1,7-dimethyluric acid, 3,7-dimethyluric acid, …
Caffeine and its metabolites in urine were quantified using ultra-high-performance liquid chromatography-electrospray ionization-tandem mass …
Caffeine--filtering the facts.
Eskenazi B. Eskenazi B. N Engl J Med. 1999 Nov 25;341(22):1688-9. doi: 10.1056/NEJM199911253412210. N Engl J Med. 1999. PMID: 10572159 No abstract available.
Oral application of 1,7-dimethylxanthine (paraxanthine) attenuates the formation of experimental cholestatic liver fibrosis.
Klemmer I, Yagi S, Gressner OA. Klemmer I, et al. Hepatol Res. 2011 Nov;41(11):1094-109. doi: 10.1111/j.1872-034X.2011.00856.x. Hepatol Res. 2011. PMID: 22032678
Recent data now point to a modulation of transforming growth factor-beta (TGF-beta) signaling by paraxanthine (1,7-dimethylxanthine [1,7-DMX]), the demethylated primary metabolite of caffeine METHODS: Twenty adult Sprague-Dawley rats were bile duct ligated (B …
Recent data now point to a modulation of transforming growth factor-beta (TGF-beta) signaling by paraxanthine (1,7-dimethyl …
Paraxanthine safety and comparison to caffeine.
Szlapinski SK, Charrette A, Guthrie N, Hilmas CJ. Szlapinski SK, et al. Front Toxicol. 2023 Feb 2;5:1117729. doi: 10.3389/ftox.2023.1117729. eCollection 2023. Front Toxicol. 2023. PMID: 36818692 Free PMC article.
Thus, investigation into an alternate stimulant with similar pharmacology but improved safety is warranted. Paraxanthine (1,7-dimethylxanthine) is the predominant metabolite of caffeine in humans with similar stimulant properties. ...
Thus, investigation into an alternate stimulant with similar pharmacology but improved safety is warranted. Paraxanthine (1,7- …
Fluvoxamine is a potent inhibitor of the metabolism of caffeine in vitro.
Rasmussen BB, Nielsen TL, Brøsen K. Rasmussen BB, et al. Pharmacol Toxicol. 1998 Dec;83(6):240-5. doi: 10.1111/j.1600-0773.1998.tb01476.x. Pharmacol Toxicol. 1998. PMID: 9868741
A high-performance liquid chromatography method was developed in order to assay 1,3-dimethylxanthine, 1,7-dimethylxanthine, 3,7-dimethylxanthine and 1,3,7-trimethyluric acid formed from caffeine by human liver microsomes. ...As expected, fluvoxamine was a ver …
A high-performance liquid chromatography method was developed in order to assay 1,3-dimethylxanthine, 1,7-dimethylxanthine …
Inhibition of acute pulmonary and systemic inflammation by 1,7-dimethylxanthine.
Geraets L, Haegens A, Weseler AR, Brauers K, Vernooy JH, Wouters EF, Bast A, Hageman GJ. Geraets L, et al. Eur J Pharmacol. 2010 Mar 10;629(1-3):132-9. doi: 10.1016/j.ejphar.2009.11.064. Epub 2009 Dec 4. Eur J Pharmacol. 2010. PMID: 19962977
Serum amyloid P component and plasma IL-6 were also lowered in 1,7-dimethylxanthine treated mice, indicating a reduced systemic inflammatory response. ...In the second model, in blood of COPD-patients and healthy controls ex vivo pre-incubated with a physiolo …
Serum amyloid P component and plasma IL-6 were also lowered in 1,7-dimethylxanthine treated mice, indicating a reduced …
An assessment of mutagenicity, genotoxicity, acute-, subacute and subchronic oral toxicity of paraxanthine (1,7-dimethylxanthine).
Purpura M, Jäger R, Falk M. Purpura M, et al. Food Chem Toxicol. 2021 Dec;158:112579. doi: 10.1016/j.fct.2021.112579. Epub 2021 Sep 28. Food Chem Toxicol. 2021. PMID: 34597720
Paraxanthine or 1,7-dimethylxanthine is a natural dietary component and the main metabolite of caffeine in humans. ...
Paraxanthine or 1,7-dimethylxanthine is a natural dietary component and the main metabolite of caffeine in humans. ...
383 results