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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1954 1
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1997 5
1998 3
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2004 23
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2007 15
2008 14
2009 17
2010 18
2011 12
2012 11
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369 results

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Page 1
ImPyβImPyβImβ-C3-18F.
Zhang H. Zhang H. 2008 Nov 4 [updated 2008 Dec 1]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2008 Nov 4 [updated 2008 Dec 1]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 20641251 Free Books & Documents. Review.
Polyamides (PAM) constructed from N-methylpyrrole (Py), N-methylimidazole (Im), 3-chlorothiophene (Ct), and N-methylhydroxypyrrole (Hp) amino acids comprise a class of synthetic oligomeric ligands that bind to the minor groove of DNA (1, 2). ...
Polyamides (PAM) constructed from N-methylpyrrole (Py), N-methylimidazole (Im), 3-chlorothiophene (Ct), and N-methylhydroxypyr …
CtPyPyIm-(R)H2Nγ-PyImPyPy-C3-18F.
Zhang H. Zhang H. 2008 Nov 4 [updated 2008 Dec 1]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2008 Nov 4 [updated 2008 Dec 1]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 20641478 Free Books & Documents. Review.
Polyamides (PAM) constructed from N-methylpyrrole (Py), N-methylimidazole (Im), 3-chlorothiophene (Ct), and N-methylhydroxypyrrole (Hp) amino acids comprise a class of synthetic oligomeric ligands that bind to the minor groove of DNA (1, 2). ...
Polyamides (PAM) constructed from N-methylpyrrole (Py), N-methylimidazole (Im), 3-chlorothiophene (Ct), and N-methylhydroxypyr …
Biology of N-methylpyrrole-N-methylimidazole hairpin polyamide.
Murty MS, Sugiyama H. Murty MS, et al. Biol Pharm Bull. 2004 Apr;27(4):468-74. doi: 10.1248/bpb.27.468. Biol Pharm Bull. 2004. PMID: 15056849 Free article. Review.
When covalently linked, hairpin polyamides made up of N-methylpyrrole (Py) and N-methylimidazole (Im) can bind to DNA in a sequence-specific manner. ...
When covalently linked, hairpin polyamides made up of N-methylpyrrole (Py) and N-methylimidazole (Im) can bind to DNA in a seq …
11-Methyl-2,3-benzodipyrrin-1-one.
Bonnett R, Motevalli M, Swanson FJ, Vallés MA. Bonnett R, et al. Acta Crystallogr C. 2004 Dec;60(Pt 12):o890-2. doi: 10.1107/S0108270104026708. Epub 2004 Nov 23. Acta Crystallogr C. 2004. PMID: 15579975
The title compound {alternative names: 11-methyl-2,3-benzopyrromethenone and 3-[(1-methylpyrrol-2-yl)methylidene]-2,3-dihydro-1H-isoindol-1-one}, C(14)H(12)N(2)O, was prepared by the base-catalysed condensation of phthalimidine with 2-formyl-1-methylpyrrole; yellow …
The title compound {alternative names: 11-methyl-2,3-benzopyrromethenone and 3-[(1-methylpyrrol-2-yl)methylidene]-2,3-dihydro-1H-isoindol-1- …
Cellular uptake of N-methylpyrrole/N-methylimidazole polyamide-dye conjugates.
Belitsky JM, Leslie SJ, Arora PS, Beerman TA, Dervan PB. Belitsky JM, et al. Bioorg Med Chem. 2002 Oct;10(10):3313-8. doi: 10.1016/s0968-0896(02)00204-3. Bioorg Med Chem. 2002. PMID: 12150878
The cellular uptake and localization properties of DNA binding N-methylpyrrole/N-methylimidazole polyamide-dye conjugates in a variety of living cells have been examined by confocal laser scanning microscopy. ...
The cellular uptake and localization properties of DNA binding N-methylpyrrole/N-methylimidazole polyamide-dye conjugat …
Alternative heterocycles for DNA recognition: an N-methylpyrazole/N-methylpyrrole pair specifies for A.T/T.A base pairs.
Nguyen DH, Szewczyk JW, Baird EE, Dervan PB. Nguyen DH, et al. Bioorg Med Chem. 2001 Jan;9(1):7-17. doi: 10.1016/s0968-0896(00)00219-4. Bioorg Med Chem. 2001. PMID: 11197348
Side-by-side pairs of three five-membered rings, N-methylpyrrole (Py), N-methylimidazole (Im), and N-methylhydroxy-pyrrole (Hp), have been demonstrated to distinguish each of the four Watson Crick base pairs in the minor groove of DNA. ...
Side-by-side pairs of three five-membered rings, N-methylpyrrole (Py), N-methylimidazole (Im), and N-methylhydroxy-pyrrole (Hp …
Cytotoxicity, crosslinking and biological activity of three mitomycins.
Cheng SY, Delgado-Cruzata L, Clement CC, Zacarias O, Concheiro-Guisan M, Towler N, Snyder T, Zheng M, Almodovar N, Gonzalez C, Romaine M, Sapse AM, Champeil E. Cheng SY, et al. Bioorg Chem. 2022 Jun;123:105744. doi: 10.1016/j.bioorg.2022.105744. Epub 2022 Mar 22. Bioorg Chem. 2022. PMID: 35349830 Free PMC article.
The drugs are: mitomycin C (1), decarbamoylmitomycin C (2), and a mitomycin-conjugate (3) whose mitosane moiety is linked to a N-methylpyrrole carboxamide. We found that, overall, both MC and compound 3 show strong similarities regarding their alkylation of DNA, whi …
The drugs are: mitomycin C (1), decarbamoylmitomycin C (2), and a mitomycin-conjugate (3) whose mitosane moiety is linked to a N-m …
DNA-Binding Properties of New Fluorescent AzaHx Amides: Methoxypyridylazabenzimidazolepyrroleimidazole/pyrrole.
Liu B, Pett L, Kiakos K, Patil PC, Satam V, Hartley JA, Lee M, Wilson WD. Liu B, et al. Chembiochem. 2018 Sep 17;19(18):1979-1987. doi: 10.1002/cbic.201800273. Epub 2018 Aug 15. Chembiochem. 2018. PMID: 29974647 Free PMC article.
Because of the 2:1 antiparallel stacking homodimer binding mode of these molecules to DNA, modification of Hx amides to 2-(p-anisyl)-4-azabenzimidazole (AzaHx) amides has successfully extended the DNA-recognition repertoire from central CG [recognized by Hx-I (I=N-methylimidazole …
Because of the 2:1 antiparallel stacking homodimer binding mode of these molecules to DNA, modification of Hx amides to 2-(p-anisyl)-4-azabe …
Carbocyclic Analogues of Distamycin and Netropsin.
Arciszewska K, Pućkowska A, Wróbel A, Drozdowska D. Arciszewska K, et al. Mini Rev Med Chem. 2019;19(2):98-113. doi: 10.2174/1389557518666181009143203. Mini Rev Med Chem. 2019. PMID: 30626311 Review.
The discovery of the details of minor groove binding drugs, such as netropsin and distamycin A, oligoamides built of 4-amino-1-methylpyrrole-2-carboxylic acid residues, allowed to develop various DNA sequence-reading molecules, named lexitropsins, capable of interac …
The discovery of the details of minor groove binding drugs, such as netropsin and distamycin A, oligoamides built of 4-amino-1-met …
369 results