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915 results

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Page 1
Integration of network toxicology and transcriptomics reveals the novel neurotoxic mechanisms of 2, 2', 4, 4'-tetrabromodiphenyl ether.
Qu T, Sun Q, Tan B, Wei H, Qiu X, Xu X, Gao H, Zhang S. Qu T, et al. J Hazard Mater. 2025 Mar 15;486:136999. doi: 10.1016/j.jhazmat.2024.136999. Epub 2024 Dec 24. J Hazard Mater. 2025. PMID: 39740552
The brominated flame retardant 2, 2', 4, 4'-tetrabromodiphenyl ether (PBDE-47) is known as a developmental neurotoxicant, yet the underlying mechanisms remain unclear. ...
The brominated flame retardant 2, 2', 4, 4'-tetrabromodiphenyl ether (PBDE-47) is known as a devel …
2,2',4,4'-Tetrabromodiphenyl ether exposure disrupts blood-testis barrier integrity through CMA-mediated ferroptosis.
Huang X, Fu Y, Wang S, Guo Q, Wu Y, Zheng X, Wang J, Wu S, Shen L, Wei G. Huang X, et al. Sci Total Environ. 2024 Oct 20;948:174738. doi: 10.1016/j.scitotenv.2024.174738. Epub 2024 Jul 14. Sci Total Environ. 2024. PMID: 39009145
2,2',4,4'-Tetrabromodiphenyl ether (PBDE-47), being the most prevalent congener of polybrominated diphenyl ethers (PBDEs), has been found to accumulate greatly in the environment and induce spermatogenesis dysfunction. ...
2,2',4,4'-Tetrabromodiphenyl ether (PBDE-47), being the most prevalent congener of polybrominated …
2,2',4,4'-Tetrabromodiphenyl ether disrupts spermatogenesis in mice by interfering with the ER-Nrf1-Tfam-mitochondria pathway.
Huang S, Xia J, Zhang X, Zhou T, Wang J, Liu T, Xu S, Liang G. Huang S, et al. Toxicol Ind Health. 2022 Mar;38(3):182-191. doi: 10.1177/07482337221081206. Epub 2022 Mar 3. Toxicol Ind Health. 2022. PMID: 35238255
2,2',4,4' -tetrabromodiphenyl ether (BDE47), a well-known endocrine disruptor of the estrogen receptor (ER) is toxic to the mitochondria and spermatogenesis. ...
2,2',4,4' -tetrabromodiphenyl ether (BDE47), a well-known endocrine disruptor of the estrogen rece …
Characterization of 2,2',4,4'-tetrabromodiphenyl ether (BDE47)-induced testicular toxicity via single-cell RNA-sequencing.
Zhang W, Xia S, Zhong X, Gao G, Yang J, Wang S, Cao M, Liang Z, Yang C, Wang J. Zhang W, et al. Precis Clin Med. 2022 Jun 20;5(3):pbac016. doi: 10.1093/pcmedi/pbac016. eCollection 2022 Sep. Precis Clin Med. 2022. PMID: 35875604 Free PMC article.
BACKGROUND: The growing male reproductive diseases have been linked to higher exposure to certain environmental compounds such as 2,2',4,4'-tetrabromodiphenyl ether (BDE47) that are widely distributed in the food chain. ...
BACKGROUND: The growing male reproductive diseases have been linked to higher exposure to certain environmental compounds such as 2, …
Effects of 2,2',4,4'-tetrabromodiphenyl ether on the development of mouse embryonic stem cells.
Xu Q, Yu M, Zhou Y, Huang Z, Huang X, Xu B, Zhou K, Chen X, Xia Y, Wang X, Lu C, Han X. Xu Q, et al. Reprod Toxicol. 2021 Dec;106:18-24. doi: 10.1016/j.reprotox.2021.09.008. Epub 2021 Sep 20. Reprod Toxicol. 2021. PMID: 34547414
2,2',4,4'-Tetrabromodiphenyl ether (BDE47) poses potential risks to reproduction and development, but the mechanism of its toxicity has not yet been elucidated. ...
2,2',4,4'-Tetrabromodiphenyl ether (BDE47) poses potential risks to reproduction and development, …
Degradation of 2,2',4,4'-tetrabromodiphenyl ether by Pycnoporus sanguineus in the presence of copper ions.
Wang M, Yin H, Peng H, Feng M, Lu G, Dang Z. Wang M, et al. J Environ Sci (China). 2019 Sep;83:133-143. doi: 10.1016/j.jes.2019.03.020. Epub 2019 Apr 2. J Environ Sci (China). 2019. PMID: 31221376
The degradation of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) by Pycnoporus sanguineus was investigated in order to explore the impact of the heavy metal Cu(2+) on BDE-47 decomposition and the subsequent formation of metabolites, as well …
The degradation of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) by Pycnoporus sanguineus was invest …
Effects of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) on reproductive and endocrine function in female zebrafish (Danio rerio).
Shi X, Wu R, Wang X, Huang W, Zheng S, Zhang Q, Peng J, Tan W, Wu K. Shi X, et al. Ecotoxicol Environ Saf. 2022 Dec 15;248:114326. doi: 10.1016/j.ecoenv.2022.114326. Epub 2022 Nov 23. Ecotoxicol Environ Saf. 2022. PMID: 36435001 Free article.
In this study, the adult female zebrafish were used to investigate the effects of 2, 2', 4, 4'-tetrabromodiphenyl ether (BDE-47) on the reproductive endocrine system and its mechanism. ...
In this study, the adult female zebrafish were used to investigate the effects of 2, 2', 4, 4'-tetrabromodiph …
2,2',4,4'-Tetrabromodiphenyl Ether (PBDE 47) Selectively Stimulates Proatherogenic PPARgamma Signatures in Human THP-1 Macrophages to Contribute to Foam Cell Formation.
Ren Q, Xie X, Zhao C, Wen Q, Pan R, Du Y. Ren Q, et al. Chem Res Toxicol. 2022 Jun 20;35(6):1023-1035. doi: 10.1021/acs.chemrestox.2c00043. Epub 2022 May 16. Chem Res Toxicol. 2022. PMID: 35575305
2,2',4,4'-Tetrabromodiphenyl ether (PBDE 47) is one of the most prominent PBDE congeners detected in the human body, suggesting that the potential health risks of PBDE 47 should be thoroughly considered. ...
2,2',4,4'-Tetrabromodiphenyl ether (PBDE 47) is one of the most prominent PBDE congeners detected …
2, 2', 4, 4'-tetrabromodiphenyl ether induces placental toxicity via activation of p38 MAPK signaling pathway in vivo and in vitro.
Liu W, Li S, Zhou Q, Fu Z, Liu P, Cao X, Xi S. Liu W, et al. Ecotoxicol Environ Saf. 2022 Oct 1;244:114034. doi: 10.1016/j.ecoenv.2022.114034. Epub 2022 Sep 2. Ecotoxicol Environ Saf. 2022. PMID: 36063615 Free article.
2, 2', 4, 4'-tetrabromodiphenyl ether (BDE-47) is one of the most important polybrominated diphenyl ethers (PBDEs) congeners, and epidemiological studies have shown that it can cause adverse pregnancy outcomes. ...
2, 2', 4, 4'-tetrabromodiphenyl ether (BDE-47) is one of the most important polybrominated dipheny …
915 results