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139 results

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Page 1
Distribution of 2,2',5,5'-Tetrachlorobiphenyl (PCB52) Metabolites in Adolescent Rats after Acute Nose-Only Inhalation Exposure.
Bullert AJ, Li X, Gautam B, Wang H, Adamcakova-Dodd A, Wang K, Thorne PS, Lehmler HJ. Bullert AJ, et al. Environ Sci Technol. 2024 Apr 9;58(14):6105-6116. doi: 10.1021/acs.est.3c09527. Epub 2024 Mar 28. Environ Sci Technol. 2024. PMID: 38547313 Free PMC article.
Because limited information about the disposition of PCBs following inhalation exposure is available, this study investigated the disposition of 2,2',5,5'-tetrachlorobiphenyl (PCB52) and its metabolites in rats following acute, nose-only inhalation of …
Because limited information about the disposition of PCBs following inhalation exposure is available, this study investigated the dispositio …
Updating "Dataset of transcriptomic changes that occur in human preadipocytes over a 3-day course of exposure to 3,3',4,4',5-Pentachlorobiphenyl (PCB126)" with additional data on exposure to 2,2',5,5'-tetrachlorobiphenyl (PCB52) or its 4-hydroxy metabolite (4-OH-PCB52).
Gourronc FA, Chimenti MS, Lehmler HJ, Ankrum JA, Klingelhutz AJ. Gourronc FA, et al. Data Brief. 2023 Jul 14;49:109415. doi: 10.1016/j.dib.2023.109415. eCollection 2023 Aug. Data Brief. 2023. PMID: 37520642 Free PMC article.
The non-dioxin-like PCB congener, PCB52 (2,2',5,5'-tetrachlorobiphenyl), is found at one of the highest levels of any congener in school air. PCB52 is oxidized in the liver to hydroxylated forms, mainly 4-OH-PCB52 (2,2',5,5'-tet …
The non-dioxin-like PCB congener, PCB52 (2,2',5,5'-tetrachlorobiphenyl), is found at one of the highest levels o …
Subacute exposure of male adolescent rats to 2,2',5,5'-tetrachlorobiphenyl-4-ol via a polymeric implant causes gene expression changes in the brain and metabolomic disruption in serum.
Wang H, Bullert AJ, Linahon MJ, Dailey ME, Doorn JA, Klingelhutz AJ, Ankrum JA, Lehmler HJ. Wang H, et al. Toxicology. 2025 Jun;514:154120. doi: 10.1016/j.tox.2025.154120. Epub 2025 Mar 15. Toxicology. 2025. PMID: 40097135 Free PMC article.
Polychlorinated biphenyls (PCBs) remain an environmental health concern due to their persistence and ongoing release from legacy and emerging sources. 2,2',5,5'-Tetrachlorobiphenyl (PCB52), a PCB congener frequently detected in the environment and huma …
Polychlorinated biphenyls (PCBs) remain an environmental health concern due to their persistence and ongoing release from legacy and emergin …
Disposition and Metabolomic Effects of 2,2',5,5'-Tetrachlorobiphenyl in Female Rats Following Intraperitoneal Exposure.
Bullert A, Li X, Zhang C, Lee K, Pulliam CF, Cagle BS, Doorn JA, Klingelhutz AJ, Robertson LW, Lehmler HJ. Bullert A, et al. bioRxiv [Preprint]. 2023 Aug 9:2023.06.19.544952. doi: 10.1101/2023.06.19.544952. bioRxiv. 2023. Update in: Environ Toxicol Pharmacol. 2023 Sep;102:104245. doi: 10.1016/j.etap.2023.104245. PMID: 37609242 Free PMC article. Updated. Preprint.
Multiple effects of 2,2',5,5'-tetrachlorobiphenyl on oxidative phosphorylation in rat liver mitochondria.
Mildaziene V, Nauciene Z, Baniene R, Grigiene J. Mildaziene V, et al. Toxicol Sci. 2002 Feb;65(2):220-7. doi: 10.1093/toxsci/65.2.220. Toxicol Sci. 2002. PMID: 11812926
An experimental investigation of the response of the multicomponent oxidative phosphorylation system to the environmental pollutant 2,2',5,5'-tetrachlorobiphenyl (2,2',5,5'-TCB) was performed by modular kinetic analysis in rat live …
An experimental investigation of the response of the multicomponent oxidative phosphorylation system to the environmental pollutant 2 …
The activities of 2,2',5,5'-tetrachlorobiphenyl, its 3,4-oxide metabolite, and 2,2',4,4'-tetrachlorobiphenyl in tumor induction and promotion assays.
Preston BD, Miller EC, Miller JA. Preston BD, et al. Carcinogenesis. 1985 Mar;6(3):451-3. doi: 10.1093/carcin/6.3.451. Carcinogenesis. 1985. PMID: 2858273
Sensitive assays for the induction of lung adenomas in A/J mice or skin papillomas in SENCAR mice failed to show activity for either 2,2',5,5'-tetrachlorobiphenyl or 2,2',5,5'-tetrachlorobiphenyl 3,4-oxide. Injections …
Sensitive assays for the induction of lung adenomas in A/J mice or skin papillomas in SENCAR mice failed to show activity for either 2 …
139 results