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Page 1
Influence of enzyme levels on the toxicity and in vitro metabolism of 2,2',5-trichlorobiphenyl in houseflies.
Saghir SA, Hansen LG. Saghir SA, et al. Ecotoxicol Environ Saf. 1994 Jul;28(2):111-20. doi: 10.1006/eesa.1994.1039. Ecotoxicol Environ Saf. 1994. PMID: 7525209
Adult female houseflies (Musca domestica) were topically dosed with 10, 15, and 20 micrograms of 2,2',5-trichlorobiphenyl (PCB-18) in acetone at 1, 5, and 15 days following emergence. ...
Adult female houseflies (Musca domestica) were topically dosed with 10, 15, and 20 micrograms of 2,2',5-trichlorobip …
Short-term distribution, metabolism, and excretion of 2,2',5-tri-, 2, 2',4,4'-tetra-, and 3,3',4,4'-tetrachlorobiphenyls in prepubertal rats.
Saghir SA, Koritz GD, Hansen LG. Saghir SA, et al. Arch Environ Contam Toxicol. 1999 Feb;36(2):213-20. doi: 10.1007/s002449900463. Arch Environ Contam Toxicol. 1999. PMID: 9888968
After 72 h, different organs were removed and extracted in acetone:hexane (1:1, v/v) to determine radioactivity. Within the first 10 h after dosing, 2,2', 5-trichlorobiphenyl (PCB 18) was rapidly excreted in urine (8-18% of the administered dose), wher …
After 72 h, different organs were removed and extracted in acetone:hexane (1:1, v/v) to determine radioactivity. Within the first 10 h after …
Disadvantaged induction of gene mutations by lower chlorinated biphenyls in V79-derived cells co-expressing mouse relative to human CYP2E1, molecular docking/dynamics studies suggesting unfavored metabolic activation by the mouse enzyme.
Luo Y, Hu K, Tu H, Xu K, Zhu S, Wang L, Liu Y. Luo Y, et al. Ecotoxicol Environ Saf. 2025 Oct 15;305:119204. doi: 10.1016/j.ecoenv.2025.119204. Epub 2025 Oct 13. Ecotoxicol Environ Saf. 2025. PMID: 41086692 Free article.
The other test compounds included 2-monochlorobiphenyl, 2,3-dichlorobiphenyl, 2,5-dichlorobiphenyl, 2,2',5-trichlorobiphenyl, and 2,4,4'-trichlorobiphenyl, which showed substrate potentials for both enzymes; indeed, all except 2,4,4'-trichlorobi …
The other test compounds included 2-monochlorobiphenyl, 2,3-dichlorobiphenyl, 2,5-dichlorobiphenyl, 2,2',5-trichloro …
Alteration of regiospecificity in biphenyl dioxygenase by active-site engineering.
Suenaga H, Watanabe T, Sato M, Ngadiman, Furukawa K. Suenaga H, et al. J Bacteriol. 2002 Jul;184(13):3682-8. doi: 10.1128/JB.184.13.3682-3688.2002. J Bacteriol. 2002. PMID: 12057964 Free PMC article.
In particular, the Ile335Phe mutant acquired the ability to degrade 2,5,2',5'-tetrachlorobiphenyl by 3,4-dioxygenation and showed bifunctional 2,3-dioxygenase and 3,4-dioxygenase activities for 2,5,2'-trichlorobiphenyl and 2,5,4'-trich …
In particular, the Ile335Phe mutant acquired the ability to degrade 2,5,2',5'-tetrachlorobiphenyl by 3,4-dioxygenation and showed bifunction …
Capillary Gas Chromatographic Separation Performances of a Tetraphenyl Porphyrin Stationary Phase.
Yan Y, Wang Z, Zhang Z, He Z, Luo L, Fan J. Yan Y, et al. Front Chem. 2022 Feb 23;10:800922. doi: 10.3389/fchem.2022.800922. eCollection 2022. Front Chem. 2022. PMID: 35281565 Free PMC article.
The unique mechanisms through which the TPP column retained polychlorinated biphenyls allowed the peak pair of 2,2',5-trichlorobiphenyl and 4,4'-dichlorobiphenyl to be resolved better on the TPP column than the HP-5MS column. ...
The unique mechanisms through which the TPP column retained polychlorinated biphenyls allowed the peak pair of 2,2',5- …
Dihydroxylation and dechlorination of chlorinated biphenyls by purified biphenyl 2,3-dioxygenase from Pseudomonas sp. strain LB400.
Haddock JD, Horton JR, Gibson DT. Haddock JD, et al. J Bacteriol. 1995 Jan;177(1):20-6. doi: 10.1128/jb.177.1.20-26.1995. J Bacteriol. 1995. PMID: 8002618 Free PMC article.
Compounds resulting from both types of reaction were produced during oxidation of 2,5,2'-trichlorobiphenyl. The broad substrate specificity and the ability to oxidize at different ring positions suggest that the biphenyl 2,3-dioxygenase is responsible …
Compounds resulting from both types of reaction were produced during oxidation of 2,5,2'-trichlorobiphenyl. The …
Biomass-derived porous material synthesized by one-step calcination method for the magnetic solid-phase extraction of polychlorinated biphenyls in water.
Lv S, Gao Y, Zhao M, Jiang X, Li X, Yang J, Chen S, Cui S. Lv S, et al. J Sep Sci. 2022 May;45(10):1693-1701. doi: 10.1002/jssc.202100884. Epub 2022 Apr 4. J Sep Sci. 2022. PMID: 35304811
The material was used in magnetic solid-phase extraction of three polychlorinated biphenyls: 2-chlorobiphenyl, 4-chlorobiphenyl, and 2,2,5-trichlorobiphenyl. Several factors were investigated, such as material amount, eluents, adsorption time, solution …
The material was used in magnetic solid-phase extraction of three polychlorinated biphenyls: 2-chlorobiphenyl, 4-chlorobiphenyl, and 2 …
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