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660 results

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Quoted phrase not found in phrase index: "dihydrocoumarone"
Page 1
2,3-Dihydrobenzofuran analogues of hallucinogenic phenethylamines.
Nichols DE, Snyder SE, Oberlender R, Johnson MP, Huang XM. Nichols DE, et al. J Med Chem. 1991 Jan;34(1):276-81. doi: 10.1021/jm00105a043. J Med Chem. 1991. PMID: 1992127
Two 2,3-dihydrobenzofuran analogues of hallucinogenic amphetamines were prepared and evaluated for activity in the two-lever drug-discrimination paradigm in rats trained to discriminate saline from LSD tartrate (0.08 mg/kg) and for the ability to displace [12 …
Two 2,3-dihydrobenzofuran analogues of hallucinogenic amphetamines were prepared and evaluated for activity in the two- …
Phytochemicals Approach for Developing Cancer Immunotherapeutics.
Yin SY, Yang NS, Lin TJ. Yin SY, et al. Front Pharmacol. 2017 Jun 19;8:386. doi: 10.3389/fphar.2017.00386. eCollection 2017. Front Pharmacol. 2017. PMID: 28674499 Free PMC article. Review.
On the other hand, some derivatives of phytochemicals, such as dihydrobenzofuran lignan (Q2-3) have been found to induce the secretion of an endogenous anticancer factor, namely IL-25, from non-malignant cells. ...
On the other hand, some derivatives of phytochemicals, such as dihydrobenzofuran lignan (Q2-3) have been found to induce the secretio …
Synthetic approaches to natural products containing 2,3-dihydrobenzofuran skeleton.
Chen Z, Pitchakuntla M, Jia Y. Chen Z, et al. Nat Prod Rep. 2019 Apr 17;36(4):666-690. doi: 10.1039/c8np00072g. Nat Prod Rep. 2019. PMID: 30488047 Review.
Covering: 2000 to 2018 Natural products containing the 2,3-dihydrobenzofuran (2,3-DHB) skeleton have been the focus of a substantial number of synthetic studies since 2000. ...
Covering: 2000 to 2018 Natural products containing the 2,3-dihydrobenzofuran (2,3-DHB) skeleton have been …
Mixed lignan-neolignans from Tarenna attenuata.
Yang XW, Zhao PJ, Ma YL, Xiao HT, Zuo YQ, He HP, Li L, Hao XJ. Yang XW, et al. J Nat Prod. 2007 Apr;70(4):521-5. doi: 10.1021/np0603931. Epub 2007 Mar 8. J Nat Prod. 2007. PMID: 17343407
By analysis of physical and spectroscopic data, the structures of the new compounds were elucidated as (1R,5R,6R)-6-{4-O-[2-(1-(4-hydroxy-3-methoxyphenyl))glycerol]-3,5-dimethoxyphenyl}-3,7-dioxabicyclo[3.3.0]octan-2-one (1), 5' '-methoxyhedyotisol A (2), 4' '-O-(8-guaiacylglycer …
By analysis of physical and spectroscopic data, the structures of the new compounds were elucidated as (1R,5R,6R)-6-{4-O-[2-(1-(4-hydroxy-3- …
Electrorearranged Difunctionalization of 4-Hydroxy-α-benzopyrones.
Karmakar I, Brahmachari G. Karmakar I, et al. J Org Chem. 2024 Aug 2;89(15):10524-10537. doi: 10.1021/acs.joc.4c00734. Epub 2024 Jul 19. J Org Chem. 2024. PMID: 39028998
We herein report the exploration of an electrosynthetic strategy as a highly efficient and straightforward alternative protocol for accessing diversely substituted and biologically promising alkyl 2-hydroxy-3-oxo-2,3-dihydrobenzofuran-2-carboxylates th …
We herein report the exploration of an electrosynthetic strategy as a highly efficient and straightforward alternative protocol for accessin …
Tactics for preclinical validation of receptor-binding radiotracers.
Lever SZ, Fan KH, Lever JR. Lever SZ, et al. Nucl Med Biol. 2017 Jan;44:4-30. doi: 10.1016/j.nucmedbio.2016.08.015. Epub 2016 Sep 3. Nucl Med Biol. 2017. PMID: 27755986 Free PMC article. Review.
INTRODUCTION: Aspects of radiopharmaceutical development are illustrated through preclinical studies of [(125)I]-(E)-1-(2-(2,3-dihydrobenzofuran-5-yl)ethyl)-4-(iodoallyl)piperazine ([(125)I]-E-IA-BF-PE-PIPZE), a radioligand for sigma-1 (sigma(1)) receptors, c …
INTRODUCTION: Aspects of radiopharmaceutical development are illustrated through preclinical studies of [(125)I]-(E)-1-(2-(2,3 …
In Vitro Effects of the Neolignan 2,3-Dihydrobenzofuran Against Leishmania Amazonensis.
de Castro Oliveira LG, Brito LM, de Moraes Alves MM, Amorim LV, Sobrinho-Júnior EP, de Carvalho CE, da Franca Rodrigues KA, Arcanjo DD, das Graças Lopes Citó AM, de Amorim Carvalho FA. de Castro Oliveira LG, et al. Basic Clin Pharmacol Toxicol. 2017 Jan;120(1):52-58. doi: 10.1111/bcpt.12639. Epub 2016 Sep 16. Basic Clin Pharmacol Toxicol. 2017. PMID: 27398818
The capability in vitro of the neolignan 2,3-dihydrobenzofuran (2,3-DBF), a commonly found constituent of propolis and other plants, to inhibit the growth of promastigote and macrophage-internalized amastigote forms of Leishmania amazonensis was …
The capability in vitro of the neolignan 2,3-dihydrobenzofuran (2,3-DBF), a commonly found constituent of …
Identification of Salt-Enhancing Compounds in Cumin.
Wang N, Tello E, Peterson DG. Wang N, et al. J Agric Food Chem. 2025 Aug 6;73(31):19652-19662. doi: 10.1021/acs.jafc.5c05398. Epub 2025 Jul 27. J Agric Food Chem. 2025. PMID: 40765361
Sensory-guided fractionation of cumin seed ethanolic extracts revealed two novel salt-enhancing compounds that were identified as 3-hydroxy-1-(4-isopropylbenzyl)piperidine-2,6-dione (compound 1, cuminodione) and (2S,3S)-5-((E)-2-carboxyvinyl)-2-((4-beta-d-glucopyranosyloxy)phenyl …
Sensory-guided fractionation of cumin seed ethanolic extracts revealed two novel salt-enhancing compounds that were identified as 3-hydroxy- …
Photoreactions of trans-1-o-Hydroxyphenyl-2-phenylcyclopropane.
Delgado J, Espinós A, Jiménez MC, Miranda MA, Roth HD, Tormos R. Delgado J, et al. J Org Chem. 1999 Sep 3;64(18):6541-6546. doi: 10.1021/jo981558g. J Org Chem. 1999. PMID: 11674655
Direct irradiation through quartz in cyclohexane gave rise mainly to ring-expanded products, 2-phenyl-3,4-dihydro-2H-benzopyran, 2, 2-benzyl-2,3-dihydrobenzofuran, 3, and 1-o-hydroxyphenylindan, 4. The major products, 2 and 3, are rationalized by intramolecul …
Direct irradiation through quartz in cyclohexane gave rise mainly to ring-expanded products, 2-phenyl-3,4-dihydro-2H-benzopyran, 2, 2-benzyl …
660 results