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In vitro antiestrogenic effects of aryl methyl sulfone metabolites of polychlorinated biphenyls and 2,2-bis(4-chlorophenyl)-1,1-dichloroethene on 17beta-estradiol-induced gene expression in several bioassay systems.
Letcher RJ, Lemmen JG, van der Burg B, Brouwer A, Bergman A, Giesy JP, van den Berg M. Letcher RJ, et al. Toxicol Sci. 2002 Oct;69(2):362-72. doi: 10.1093/toxsci/69.2.362. Toxicol Sci. 2002. PMID: 12377985
Methylsulfonyl (MeSO(2)) metabolites of polychlorinated biphenyls (PCBs) and 2,2-bis(4-chlorophenyl)-1,1-dichloroethene (4,4'-DDE), itself a metabolite of the insecticide 4,4'-DDT, are emerging as a major class of contaminants in the tissues of wildlife and humans. We investigate …
Methylsulfonyl (MeSO(2)) metabolites of polychlorinated biphenyls (PCBs) and 2,2-bis(4-chlorophenyl)-1,1-dichloroethene (4,4'-DDE), itself a …
Effects of polychlorinated biphenyls in rat liver: quantitative analysis of enzyme-altered foci.
Luebeck EG, Moolgavkar SH, Buchmann A, Schwarz M. Luebeck EG, et al. Toxicol Appl Pharmacol. 1991 Dec;111(3):469-84. doi: 10.1016/0041-008x(91)90251-9. Toxicol Appl Pharmacol. 1991. PMID: 1684071
This analysis included 4-monochlorobiphenyl, 2,2',4,5'-tetrachlorobiphenyl, 3,3',4,4'-tetrachlorobiphenyl and 3-methylcholanthrene, all administered at 150 mumol/kg body wt, and phenobarbital which was administered continuously in the diet at 0. …
This analysis included 4-monochlorobiphenyl, 2,2',4,5'-tetrachlorobiphenyl, 3,3',4,4'-tetrachlorobiphenyl …
Effects of polychlorinated biphenyls in rat liver: correlation between primary subcellular effects and promoting activity.
Buchmann A, Ziegler S, Wolf A, Robertson LW, Durham SK, Schwarz M. Buchmann A, et al. Toxicol Appl Pharmacol. 1991 Dec;111(3):454-68. doi: 10.1016/0041-008x(91)90250-i. Toxicol Appl Pharmacol. 1991. PMID: 1684070
Out of the series of polyhalogenated biphenyls tested, promoting effects were seen with the following compounds: 2,2',4,5'-tetrachlorobiphenyl, 3,3',4,4'-tetrachlorobiphenyl, 2,3,4,4',5-pentachlorobiphenyl, and 3,3',4,4'-tetrabromobiphenyl, wher …
Out of the series of polyhalogenated biphenyls tested, promoting effects were seen with the following compounds: 2,2',4 …
Inhibition of cell-cell communication by methylsulfonyl metabolites of polychlorinated biphenyl congeners in rat liver epithelial IAR 20 cells.
Kato Y, Kenne K, Haraguchi K, Masuda Y, Kimura R, Wärngård L. Kato Y, et al. Arch Toxicol. 1998 Feb;72(3):178-82. doi: 10.1007/s002040050484. Arch Toxicol. 1998. PMID: 9520141
The results demonstrated that at non-cytotoxic concentrations 2,2',4',5-tetrachlorobiphenyl, 2,2',4',5,5'-pentachlorobiphenyl (2,2',4',5,5'-pentaCB), 2,2',4',5,5',6-hexachlorobiphenyl (2,2',4',5,5', 6-hexaCB), and their 3- a …
The results demonstrated that at non-cytotoxic concentrations 2,2',4',5-tetrachlorobiphenyl, 2,2', …