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599 results

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Quoted phrases not found in phrase index: "2,2',6-tribromodiphenyl ether", "steoroids"
Page 1
Recent use of consumer and personal care products and exposures to select endocrine disrupting chemicals among urban children with asthma.
Fandiño-Del-Rio M, Matsui EC, Calafat AM, Koehl R, Botelho JC, Woo H, Boyle M, Hansel NN, McCormack M, Quirós-Alcalá L. Fandiño-Del-Rio M, et al. J Expo Sci Environ Epidemiol. 2024 Jul;34(4):637-646. doi: 10.1038/s41370-024-00693-8. Epub 2024 Jun 18. J Expo Sci Environ Epidemiol. 2024. PMID: 38890543 Free PMC article.
BACKGROUND: Emerging studies suggest that endocrine disrupting chemicals (EDCs) in personal care and other consumer products are linked with various adverse health effects, including respiratory and reproductive effects. ...RESULTS: Increased concentrations t …
BACKGROUND: Emerging studies suggest that endocrine disrupting chemicals (EDCs) in personal care and other consumer products a …
2,2',4,4'-Tetrabromodiphenyl ether exposure disrupts blood-testis barrier integrity through CMA-mediated ferroptosis.
Huang X, Fu Y, Wang S, Guo Q, Wu Y, Zheng X, Wang J, Wu S, Shen L, Wei G. Huang X, et al. Sci Total Environ. 2024 Oct 20;948:174738. doi: 10.1016/j.scitotenv.2024.174738. Epub 2024 Jul 14. Sci Total Environ. 2024. PMID: 39009145
2,2',4,4'-Tetrabromodiphenyl ether (PBDE-47), being the most prevalent congener of polybrominated diphenyl ethers (PBDEs), has been found to accumulate greatly in the environment and induce spermatogenesis dysfunction. ...These collective findin …
2,2',4,4'-Tetrabromodiphenyl ether (PBDE-47), being the most prevalent congener of polybrominated diphenyl ethers …
Low level exposure to BDE-47 facilitates the development of prostate cancer through TOP2A/LDHA/lactylation positive feedback circuit.
Tian L, Zhou N, Zhao N, Qiao M, He M, Mao Z, Xu W, Xu D, Wang Y, Xu Y, Chen T. Tian L, et al. Environ Res. 2024 Dec 15;263(Pt 2):120094. doi: 10.1016/j.envres.2024.120094. Epub 2024 Oct 2. Environ Res. 2024. PMID: 39362459
2,2',4,4'-tetra brominated diphenyl ether (BDE-47) is one of the most widely distributed congeners of polybrominated diphenyl ethers. While the relationships between BDE-47 exposure and other hormone-dependent cancers (such as breast cancer …
2,2',4,4'-tetra brominated diphenyl ether (BDE-47) is one of the most widely distributed congeners of polybrominated di …
2,2',4,4'-Tetrabromodiphenyl ether disrupts spermatogenesis in mice by interfering with the ER-Nrf1-Tfam-mitochondria pathway.
Huang S, Xia J, Zhang X, Zhou T, Wang J, Liu T, Xu S, Liang G. Huang S, et al. Toxicol Ind Health. 2022 Mar;38(3):182-191. doi: 10.1177/07482337221081206. Epub 2022 Mar 3. Toxicol Ind Health. 2022. PMID: 35238255
2,2',4,4' -tetrabromodiphenyl ether (BDE47), a well-known endocrine disruptor of the estrogen receptor (ER) is toxic to the mitochondria and spermatogenesis. This study aimed to explore the mechanism of BDE47 on spermatogenesis in …
2,2',4,4' -tetrabromodiphenyl ether (BDE47), a well-known endocrine disruptor of the estrogen receptor (E …
Human CYP enzyme-activated genotoxicity of 2,2',4,4'-tetrabromobiphenyl ether in mammalian cells.
Song M, Wang Y, Chen Z, Gao H, Yang Z, Yu H, Liu Y. Song M, et al. Chemosphere. 2022 Mar;291(Pt 1):132784. doi: 10.1016/j.chemosphere.2021.132784. Epub 2021 Nov 3. Chemosphere. 2022. PMID: 34742755
Polybrominated biphenyl ethers (PBDEs) are a group of persistent organic pollutants with endocrine-disrupting, neurotoxic, tumorigenic and DNA-damaging activities. They are hydroxylated by human liver microsomal CYP enzymes, however, their mutagenicity remains unkno …
Polybrominated biphenyl ethers (PBDEs) are a group of persistent organic pollutants with endocrine-disrupting, neurotoxic, tum …
Modulating tumor-associated macrophages through CSF1R inhibition: a potential therapeutic strategy for HNSCC.
Chen K, Li X, Dong S, Guo Y, Luo Z, Zhuang SM, Liu J, Liu T, Liao J, Wen W. Chen K, et al. J Transl Med. 2025 Jan 8;23(1):27. doi: 10.1186/s12967-024-06036-3. J Transl Med. 2025. PMID: 39780232 Free PMC article.
PURPOSE: Tumor-associated macrophages (TAMs) are pivotal immune cells within the tumor microenvironment (TME), exhibiting dual roles across various cancer types. Depending on the context, TAMs can either suppress tumor progression and weaken drug sensi …
PURPOSE: Tumor-associated macrophages (TAMs) are pivotal immune cells within the tumor microenvironment (TME), exhibiting dual …
Organophosphate Esters Disrupt Steroidogenesis in KGN Human Ovarian Granulosa Cells.
Wang X, Lee E, Hales BF, Robaire B. Wang X, et al. Endocrinology. 2023 Jun 6;164(7):bqad089. doi: 10.1210/endocr/bqad089. Endocrinology. 2023. PMID: 37288667 Free PMC article.
KGN cells were exposed for 48 hours to 1 of 5 OPEs (1-50muM): triphenyl phosphate (TPHP), tris(methylphenyl) phosphate (TMPP), isopropylated triphenyl phosphate (IPPP), tert-butylphenyl diphenyl phosphate (BPDP), and tributoxyethyl phosphate (TBOEP), or to a polybrominated diphen …
KGN cells were exposed for 48 hours to 1 of 5 OPEs (1-50muM): triphenyl phosphate (TPHP), tris(methylphenyl) phosphate (TMPP), isopropylated …
Perinatal exposure to 2,2',4'4' -Tetrabromodiphenyl ether induces testicular toxicity in adult rats.
Khalil A, Parker M, Brown SE, Cevik SE, Guo LW, Jensen J, Olmsted A, Portman D, Wu H, Suvorov A. Khalil A, et al. Toxicology. 2017 Aug 15;389:21-30. doi: 10.1016/j.tox.2017.07.006. Epub 2017 Jul 13. Toxicology. 2017. PMID: 28712647
Since 1965, polybrominated diphenyl ethers (PBDEs) have been used internationally as flame-retardant additives. PBDEs were recently withdrawn from commerce in North America and Europe due to their environmental persistence, bioaccumulative properties and endocrine-d …
Since 1965, polybrominated diphenyl ethers (PBDEs) have been used internationally as flame-retardant additives. PBDEs were recently w …
MiR-24-3p/Dio3 axis is essential for BDE47 to induce local thyroid hormone disorder and neurotoxicity.
Liu M, Yu Z, Zhao Z, Yang F, Zhou M, Wang C, Tian X, Zhang B, Liang G, Liu X, Shao J. Liu M, et al. Toxicology. 2023 Jun 1;491:153527. doi: 10.1016/j.tox.2023.153527. Epub 2023 Apr 26. Toxicology. 2023. PMID: 37116683
BDE47 (2,2,4,4-tetrabromodiphenyl ether) is a member of the most important congeners of polybrominated diphenyl ethers (PBDEs) and has been identified as a developmental, reproductive and nervous system toxicant and endocrine system disru …
BDE47 (2,2,4,4-tetrabromodiphenyl ether) is a member of the most important congeners of polybrominated diphenyl ethe …
Impact of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) exposure on reproductive development in adolescent offspring.
Tan W, Wu K, Shao C, Zhou Y, Zheng S, Ma Y, Peng J, Cao K, Shi X, Liu C. Tan W, et al. Toxicol Appl Pharmacol. 2025 Nov;504:117535. doi: 10.1016/j.taap.2025.117535. Epub 2025 Aug 30. Toxicol Appl Pharmacol. 2025. PMID: 40889560
However, the long-term reproductive toxicity of PBDEs following perinatal exposure remains poorly understood. This study investigated the effects of perinatal exposure to 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) on reproductive development in …
However, the long-term reproductive toxicity of PBDEs following perinatal exposure remains poorly understood. This study investigated …
599 results