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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1781 1
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1797 1
1799 1
1805 1
1806 2
1822 1
1826 1
1827 4
1828 1
1829 1
1832 1
1835 2
1836 1
1838 1
1839 4
1840 2
1841 9
1843 2
1844 5
1845 5
1846 14
1847 6
1848 5
1849 2
1850 1
1851 3
1852 2
1853 4
1854 3
1855 6
1856 1
1857 5
1858 4
1859 3
1860 2
1861 7
1862 1
1863 1
1864 4
1865 2
1866 5
1867 9
1868 9
1869 5
1870 11
1871 8
1872 20
1873 9
1874 3
1875 6
1876 6
1877 10
1878 9
1879 9
1880 4
1881 13
1882 8
1883 3
1884 5
1885 16
1886 5
1887 12
1888 3
1889 7
1890 6
1891 10
1892 13
1893 12
1894 6
1895 2
1896 9
1897 10
1898 10
1899 3
1900 6
1901 6
1902 9
1903 16
1904 14
1905 14
1906 9
1907 10
1908 14
1909 76
1910 13
1911 20
1912 22
1913 28
1914 20
1915 23
1916 13
1917 15
1918 6
1919 16
1920 14
1921 5
1922 16
1923 23
1924 16
1925 25
1926 30
1927 23
1928 24
1929 30
1930 38
1931 22
1932 37
1933 34
1934 34
1935 33
1936 40
1937 45
1938 36
1939 37
1940 20
1941 24
1942 23
1943 18
1944 19
1945 88
1946 310
1947 938
1948 958
1949 939
1950 1143
1951 1362
1952 1199
1953 1337
1954 1227
1955 1311
1956 1326
1957 1308
1958 1295
1959 1069
1960 374
1961 448
1962 477
1963 689
1964 901
1965 1433
1966 2673
1967 3325
1968 3640
1969 4037
1970 4541
1971 4724
1972 5415
1973 5752
1974 6438
1975 10054
1976 10207
1977 9826
1978 10372
1979 11572
1980 12657
1981 13448
1982 14589
1983 16507
1984 17962
1985 18267
1986 19296
1987 20905
1988 24195
1989 27602
1990 28448
1991 28795
1992 30377
1993 32078
1994 33446
1995 34796
1996 36536
1997 37684
1998 39017
1999 40929
2000 44292
2001 45457
2002 47625
2003 51012
2004 55401
2005 59403
2006 63111
2007 67026
2008 71176
2009 74687
2010 81982
2011 89247
2012 96371
2013 101260
2014 107512
2015 112850
2016 113938
2017 118422
2018 123852
2019 130042
2020 150078
2021 160458
2022 154445
2023 143931
2024 146495
2025 159031
2026 81145
2027 5

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2,941,397 results

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Quoted phrases not found in phrase index: "2,4-dichloro-6-phenylphenol", "steoroids"
Page 1
Endocrine Disruptors and Breast Cancer: A Comprehensive Review.
Czaczkowska L, Jabłońska E, Ratajczak-Wrona W. Czaczkowska L, et al. Biomedicines. 2025 Nov 13;13(11):2774. doi: 10.3390/biomedicines13112774. Biomedicines. 2025. PMID: 41301867 Free PMC article. Review.
Breast cancer is one of the most prevalent malignancies affecting women worldwide. Among environmental risk factors, increasing attention has been given to endocrine-disrupting chemicals (EDCs), which can interfere with hormonal signaling pathways. ...They ca …
Breast cancer is one of the most prevalent malignancies affecting women worldwide. Among environmental risk factors, increasing atten …
Assays to measure estrogen and androgen agonists and antagonists.
Soto AM, Michaelson CL, Prechtl NV, Weill BC, Sonnenschein C, Olea-Serrano F, Olea N. Soto AM, et al. Adv Exp Med Biol. 1998;444:9-23; discussion 23-8. doi: 10.1007/978-1-4899-0089-0_3. Adv Exp Med Biol. 1998. PMID: 10026930 Review.
The endocrine and reproductive effects of xenobiotics are believed to be due to their 1) mimicking the effects of endogenous hormones such as estrogens and androgens, 2) antagonizing the effects of normal, endogenous hormones, 3) altering the pattern of synth …
The endocrine and reproductive effects of xenobiotics are believed to be due to their 1) mimicking the effects of endogenous h …
Endocrinology of male infertility.
de Kretser DM. de Kretser DM. Br Med Bull. 1979 May;35(2):187-92. doi: 10.1093/oxfordjournals.bmb.a071568. Br Med Bull. 1979. PMID: 387166 Review.
For example, replacement therapy for gonadotropin deficiency is successful. Androgen injections of testosterone esters will suppress spermatogenesis, so when treatment is stopped, sperm counts will rebound to concentrations greater than pretreatment le …
For example, replacement therapy for gonadotropin deficiency is successful. Androgen injections of testosterone esters will su …
Benzophenone-2 exerts reproductive toxicity in male rats.
Broniowska Ż, Tomczyk I, Grzmil P, Bystrowska B, Skórkowska A, Maciejska A, Kazek G, Budziszewska B. Broniowska Ż, et al. Reprod Toxicol. 2023 Sep;120:108450. doi: 10.1016/j.reprotox.2023.108450. Epub 2023 Aug 4. Reprod Toxicol. 2023. PMID: 37543253
Benzophenone derivatives such as benzophenone-2 (BP-2) belong to the group of endocrine disrupting compounds (EDCs). Increased exposure to EDCs is considered to be an important factor behind the decline of human fertility. ...It was shown …
Benzophenone derivatives such as benzophenone-2 (BP-2) belong to the group of endocrine disrupting compounds (EDCs …
Epigenetics, spermatogenesis and male infertility.
Rajender S, Avery K, Agarwal A. Rajender S, et al. Mutat Res. 2011 May-Jun;727(3):62-71. doi: 10.1016/j.mrrev.2011.04.002. Epub 2011 Apr 16. Mutat Res. 2011. PMID: 21540125 Review.
Environmental toxins/drugs may affect fertility via epigenetic modifications. For example, 5-aza-2'-deoxycytidine, an anticancer agent, causes a decrease in global DNA methylation that leads to altered sperm morphology, decreased sperm motility, decrea …
Environmental toxins/drugs may affect fertility via epigenetic modifications. For example, 5-aza-2'-deoxycytidine, an anticanc …
Impact of gender-affirming hormone therapy on spermatogenesis: analysis of testicular histological specimens.
Wilk Goldsher Y, Al-Hadi H, Mullen B, Potter E, MacLeod E, Lajkosz K, Karavani G, Krakowsky Y, Grober ED, Millman AL. Wilk Goldsher Y, et al. Hum Reprod. 2026 Jan 1;41(1):78-85. doi: 10.1093/humrep/deaf216. Hum Reprod. 2026. PMID: 41206903
SUMMARY ANSWER: Cyproterone acetate (CPA) and progesterone significantly impair spermatogenesis, whereas spironolactone does not, compared to no use of anti-androgen. ...GAHT included estrogen (n = 287, 100%), progesterone (n = 73, 25.4%), and a …
SUMMARY ANSWER: Cyproterone acetate (CPA) and progesterone significantly impair spermatogenesis, whereas spironolactone does n …
Strengths and weaknesses of in vitro assays for estrogenic and androgenic activity.
Soto AM, Maffini MV, Schaeberle CM, Sonnenschein C. Soto AM, et al. Best Pract Res Clin Endocrinol Metab. 2006 Mar;20(1):15-33. doi: 10.1016/j.beem.2005.09.001. Best Pract Res Clin Endocrinol Metab. 2006. PMID: 16522517 Review.
The endocrine and reproductive effects of xenobiotics are believed to be due to (1) their mimicking the effects of endogenous hormones; (2) their antagonizing the effects of endogenous hormones; (3) their altering the pattern of synthesis and metabolism of na …
The endocrine and reproductive effects of xenobiotics are believed to be due to (1) their mimicking the effects of endogenous …
The pharmacology of nomegestrol acetate.
Ruan X, Seeger H, Mueck AO. Ruan X, et al. Maturitas. 2012 Apr;71(4):345-53. doi: 10.1016/j.maturitas.2012.01.007. Epub 2012 Feb 24. Maturitas. 2012. PMID: 22364709 Review.
Nomegestrol acetate (NOMAC) is a 19-norprogesterone derivative with high biological activity at the progesterone receptor, a weak anti-androgenic effect, but with no binding to estrogen, glucocorticoid or mineralocorticoid receptors. ...While there has …
Nomegestrol acetate (NOMAC) is a 19-norprogesterone derivative with high biological activity at the progesterone receptor, a weak ant …
Synthesis and anticancer properties of a hybrid molecule with the testosterone and estradiol head-groups.
Paquin A, Nolin F, Bouzriba C, Fortin S, Sevrioukova IF, Bérubé G. Paquin A, et al. Steroids. 2024 Sep;209:109469. doi: 10.1016/j.steroids.2024.109469. Epub 2024 Jul 9. Steroids. 2024. PMID: 38992454 Free PMC article.
This is the first report on a unique hybrid molecule made of estradiol and testosterone (TS). This distinctive hybrid molecule (1) was designed to interact with both the estrogen receptor (ER) and the androgen receptor (AR) found in hormone-depe …
This is the first report on a unique hybrid molecule made of estradiol and testosterone (TS). This distinctive hybrid molecule …
Pharmacology of vorozole.
Wouters W, Van Ginckel R, Krekels M, Bowden C, De Coster R. Wouters W, et al. J Steroid Biochem Mol Biol. 1993 Mar;44(4-6):617-21. doi: 10.1016/0960-0760(93)90268-2. J Steroid Biochem Mol Biol. 1993. PMID: 8386540
In ovariectomized nude mice, bearing an estrogen-producing JEG-3 choriocarcinoma, 5 days treatment with vorozole, dose-dependently reduced uterus weight and completely inhibited tumor aromatase, measured ex vivo. ...In LHRH/ACTH-injected male rats and …
In ovariectomized nude mice, bearing an estrogen-producing JEG-3 choriocarcinoma, 5 days treatment with vorozole, dose-dependently re …
2,941,397 results
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