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Page 1
Theoretical calculation studies on the rearrangement mechanisms of arenesulfenanilides to generate o- and p-aminodiphenyl sulfides.
Liu G, Hou S, Xu J. Liu G, et al. Org Biomol Chem. 2019 Dec 4;17(47):10088-10096. doi: 10.1039/c9ob02202c. Org Biomol Chem. 2019. PMID: 31754666
The thermal and acid-catalyzed rearrangement mechanisms of arenesulfenanilides were investigated theoretically via density functional theory (DFT) calculations. The results indicate that the o-aminodiphenyl sulfide rearrangement involves a novel S[1,3]-sigmatropic s …
The thermal and acid-catalyzed rearrangement mechanisms of arenesulfenanilides were investigated theoretically via density functional theory …
Total Synthesis of Carbazomycins E and F.
Shima Y, Feng Y, Mori A, Okano K. Shima Y, et al. J Org Chem. 2024 Jun 7;89(11):8185-8191. doi: 10.1021/acs.joc.4c01004. Epub 2024 May 29. J Org Chem. 2024. PMID: 38809152
Total synthesis of carbazomycins E and F was achieved by double functionalization of an aryne intermediate generated from a 2-aminobiphenyl derivative. The tethered amino group underwent nucleophilic addition to the aryne intermediate to construct the carbazole skel …
Total synthesis of carbazomycins E and F was achieved by double functionalization of an aryne intermediate generated from a 2-amin …
Discovery of o-aminodiphenyl-based USP7 inhibitor for immune activation and antitumor response in colorectal cancer.
Jia G, Wang Y, Zhou W, Huang X, Song Z. Jia G, et al. Int Immunopharmacol. 2025 Dec 10;167:115732. doi: 10.1016/j.intimp.2025.115732. Epub 2025 Oct 30. Int Immunopharmacol. 2025. PMID: 41172816
METHODS: Through screening, synthesis, and optimization, we identified an o-aminodiphenyl derivative, U-20, as a potent USP7 inhibitor (IC50 = 83 nM). USP7 inhibition, PD-L1 modulation, and immune activation were evaluated using in vitro enzymatic and cellular assay …
METHODS: Through screening, synthesis, and optimization, we identified an o-aminodiphenyl derivative, U-20, as a potent USP7 i …
Purification and characterization of 2'aminobiphenyl-2,3-diol 1,2-dioxygenase from Pseudomonas sp. LD2.
Gibbs PR, Riddle RR, Marchal L, Benedik MJ, Willson RC. Gibbs PR, et al. Protein Expr Purif. 2003 Nov;32(1):35-43. doi: 10.1016/S1046-5928(03)00096-2. Protein Expr Purif. 2003. PMID: 14680937
Carbazole is a nitrogen-containing heteroaromatic compound that occurs as a widespread and mutagenic environmental pollutant. The 2'aminobiphenyl-2,3-diol 1,2-dioxygenase involved in carbazole degradation was purified to near electrophoretic homogeneity from …
Carbazole is a nitrogen-containing heteroaromatic compound that occurs as a widespread and mutagenic environmental pollutant. The 2' …
t-Bu(3)P-Coordinated 2-Phenylaniline-Based Palladacycle Complex as a Precatalyst for the Suzuki Cross-coupling Polymerization of Aryl Dibromides with Aryldiboronic Acids.
Zhang HH, Xing CH, Tsemo GB, Hu QS. Zhang HH, et al. ACS Macro Lett. 2013 Jan 15;2(1):10-13. doi: 10.1021/mz300479b. ACS Macro Lett. 2013. PMID: 23687619 Free PMC article.
t -Bu(3)P-Coordinated 2-phenylaniline-based palladacycle complex, [2'-(amino-kN)[1,1'-biphenyl]-2-yl-kC]chloro(tri-t-butylphosphine)palladium, as a general, highly efficient precatalyst for the Suzuki cross-coupling polymerization of aryl dibromides with aryldiboron …
t -Bu(3)P-Coordinated 2-phenylaniline-based palladacycle complex, [2'-(amino-kN)[1,1'-biphenyl]-2-yl-kC]chloro(tri-t-butylphos …
Reversible Chromism of Tethered Ruthenium(II) Complexes in the Solid State.
Martínez-Peña F, Infante-Tadeo S, Sánchez Costa J, Pizarro AM. Martínez-Peña F, et al. Inorg Chem. 2023 May 1;62(17):6779-6785. doi: 10.1021/acs.inorgchem.3c00517. Epub 2023 Apr 20. Inorg Chem. 2023. PMID: 37079909
Tethered ruthenium(II) complexes [Ru(eta(6):kappa(1)-arene:N)Cl(2)] (where arene:N is 2-aminobiphenyl (1) and 2-benzylpyridine (2)) can convert into their open-tethered chlorido counterparts [Ru(eta(6)-arene:NH)Cl(3)], 1.HCl and 2.HCl, at room temperature via solid- …
Tethered ruthenium(II) complexes [Ru(eta(6):kappa(1)-arene:N)Cl(2)] (where arene:N is 2-aminobiphenyl (1) and 2-benzylpyridine …
tBu(3)P-Coordinated 2-Phenylaniline-Based Palladacycle Complex As Precatalyst for Pd-Catalyzed Coupling Reactions of Aryl Halides with Polyfluoroarenes via C-H Activation Strategy.
Zhang HH, Dong J, Hu QS. Zhang HH, et al. European J Org Chem. 2014 Feb 1;2014(6):1327-1332. doi: 10.1002/ejoc.201301272. European J Org Chem. 2014. PMID: 24778575 Free PMC article.
tBu(3)P-Coordinated 2-phenylaniline-based palladacycle complex was demonstrated to be an efficient precatalyst for Pd-catalyzed coupling reactions of aryl halides with polyfluoroarenes via C-H activation strategy. The readily accessibility and easy handling nature o …
tBu(3)P-Coordinated 2-phenylaniline-based palladacycle complex was demonstrated to be an efficient precatalyst for Pd-catalyze …
Cyclooxygenase-2 expression is up-regulated by 2-aminobiphenyl in a ROS and MAPK-dependent signaling pathway in a bladder cancer cell line.
Chen CC, Cheng YY, Chen SC, Tuan YF, Chen YJ, Chen CY, Chen LC. Chen CC, et al. Chem Res Toxicol. 2012 Mar 19;25(3):695-705. doi: 10.1021/tx2004689. Epub 2012 Feb 15. Chem Res Toxicol. 2012. PMID: 22288910
In this study, we have demonstrated that 2-aminobiphenyl (2-ABP) up-regulated the expression of COX-2 in a dose- and time-dependent manner in TSGH-8301 bladder cancer cells. ...
In this study, we have demonstrated that 2-aminobiphenyl (2-ABP) up-regulated the expression of COX-2 in a dose- and ti …
94 results